Fixation time does not affect expression of HER2/neu: A pilot study

American Journal of Clinical Pathology

Volumn 134, Issue 4, 2010, Pages 594-596

  Ibarra, Julio A ^a   Rogers, Lowell W ^b  

^a Memorial Care   (United States)

^b LONG BEACH MEMORIAL MEDICAL CENTER   (United States)

Author keywords

Breast cancer; Fixation time; HER2 neu; Immunohistochemistry

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; FORMALDEHYDE; MONOCLONAL ANTIBODY; FIXATIVE;

ARTICLE; BREAST CANCER; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MOLECULAR CLONING; PRIORITY JOURNAL; PROTEIN EXPRESSION; TIME; ANIMAL; BREAST TUMOR; CHEMISTRY; DIAGNOSTIC USE; FEMALE; PILOT STUDY; PROCEDURES; RABBIT; STAINING;

ANIMALS; ANTIBODIES, MONOCLONAL; BREAST NEOPLASMS; FEMALE; FIXATIVES; FORMALDEHYDE; HUMANS; IMMUNOHISTOCHEMISTRY; PILOT PROJECTS; RABBITS; RECEPTOR, ERBB-2; STAINING AND LABELING; TIME FACTORS;

EID: 77957377568     PISSN: 00029173     EISSN: 19437722     Source Type: Journal    
DOI: 10.1309/AJCPAIJPSN4A9MJI     Document Type: Article

References (5)

1. American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer. Arch Pathol Lab Med. 2007;131:18-43.
2. CAP Commission on Laboratory Accreditation. Anatomic Pathology checklist. Revised June 15, 2009. http://www.cap.org. Accessed July 2010.
3. Ibarra JA, Rogers LW, Kyshtoobayeva A, et al. Fixation time does not affect the expression of estrogen receptor. Am J Clin Pathol. 2010;133:747-755.
4. Khoury T, Sait S, Hwang H, et al. Delay to formalin fixation effect on breast biomarkers. Mod Pathol. 2009;22:1457-1467.
5. Dintzis SM, Allison KH. Effect of formalin fixation time on Her2 expression by immunohistochemical technique [abstract]. Mod Pathol. 2010;23(suppl 1):44A. Abstract 186.