-
1
-
-
70349956433
-
Finding the missing heritability of complex diseases
-
Manolio TA, Collins FS, Cox NJ, et al. Finding the missing heritability of complex diseases. Nature 2009; 461:747-753.
-
(2009)
Nature
, vol.461
, pp. 747-753
-
-
Manolio, T.A.1
Collins, F.S.2
Cox, N.J.3
-
2
-
-
38649132270
-
Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans
-
DOI 10.1038/ng.75, PII NG75
-
Kathiresan S, Melander O, Guiducci C, et al. Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. Nat Genet 2008; 40:189-197. (Pubitemid 351171402)
-
(2008)
Nature Genetics
, vol.40
, Issue.2
, pp. 189-197
-
-
Kathiresan, S.1
Melander, O.2
Guiducci, C.3
Surti, A.4
Burtt, N.P.5
Rieder, M.J.6
Cooper, G.M.7
Roos, C.8
Voight, B.F.9
Havulinna, A.S.10
Wahlstrand, B.11
Hedner, T.12
Corella, D.13
Tai, E.S.14
Ordovas, J.M.15
Berglund, G.16
Vartiainen, E.17
Jousilahti, P.18
Hedblad, B.19
Taskinen, M.-R.20
Newton-Cheh, C.21
Salomaa, V.22
Peltonen, L.23
Groop, L.24
Altshuler, D.M.25
Orho-Melander, M.26
more..
-
3
-
-
58149163149
-
Common variants at 30 loci contribute to polygenic dyslipidemia
-
Kathiresan S, Willer CJ, Peloso GM, et al. Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet 2009; 41:56-65.
-
(2009)
Nat Genet
, vol.41
, pp. 56-65
-
-
Kathiresan, S.1
Willer, C.J.2
Peloso, G.M.3
-
4
-
-
65949107547
-
Common genetic variation and human traits
-
Goldstein DB. Common genetic variation and human traits. N Engl J Med 2009; 360:1696-1698.
-
(2009)
N Engl J Med
, vol.360
, pp. 1696-1698
-
-
Goldstein, D.B.1
-
5
-
-
75149150236
-
Polymorphisms identified through genomewide association studies and their associations with type 2 diabetes in Chinese, Malays, and Asian-Indians in Singapore
-
Tan JT, Ng DP, Nurbaya S, et al. Polymorphisms identified through genomewide association studies and their associations with type 2 diabetes in Chinese, Malays, and Asian-Indians in Singapore. J Clin Endocrinol Metab 2010; 95:390-397.
-
(2010)
J Clin Endocrinol Metab
, vol.95
, pp. 390-397
-
-
Tan, J.T.1
Ng, D.P.2
Nurbaya, S.3
-
6
-
-
64349100189
-
Polymorphisms at newly identified lipid-associated loci are associated with blood lipids and cardiovascular disease in an Asian Malay population
-
Tai ES, Sim XL, Ong TH, et al. Polymorphisms at newly identified lipid-associated loci are associated with blood lipids and cardiovascular disease in an Asian Malay population. J Lipid Res 2009; 50:514-520.
-
(2009)
J Lipid Res
, vol.50
, pp. 514-520
-
-
Tai, E.S.1
Sim, X.L.2
Ong, T.H.3
-
7
-
-
76249098866
-
Long-range gene regulation links genomic type 2 diabetes and obesity risk regions to HHEX, SOX4, and IRX3
-
Ragvin A, Moro E, Fredman D, et al. Long-range gene regulation links genomic type 2 diabetes and obesity risk regions to HHEX, SOX4, and IRX3. Proc Natl Acad Sci U S A 2010; 107:775-780.
-
(2010)
Proc Natl Acad Sci u S A
, vol.107
, pp. 775-780
-
-
Ragvin, A.1
Moro, E.2
Fredman, D.3
-
8
-
-
70349640639
-
Genome-wide comparisons of variation in linkage disequilibrium
-
Teo YY, Fry AE, Bhattacharya K, et al. Genome-wide comparisons of variation in linkage disequilibrium. Genome Res 2009; 19:1849-1860.
-
(2009)
Genome Res
, vol.19
, pp. 1849-1860
-
-
Teo, Y.Y.1
Fry, A.E.2
Bhattacharya, K.3
-
9
-
-
77249134594
-
Rare variants create synthetic genome-wide associations
-
Dickson SP, Wang K, Krantz I, et al. Rare variants create synthetic genome-wide associations. PLoS Biol 2010; 8:e1000294.
-
(2010)
PLoS Biol
, vol.8
-
-
Dickson, S.P.1
Wang, K.2
Krantz, I.3
-
10
-
-
3843056691
-
Multiple rare alleles contribute to low plasma levels of HDL cholesterol
-
DOI 10.1126/science.1099870
-
Cohen JC, Kiss RS, Pertsemlidis A, et al. Multiple rare alleles contribute to low plasma levels of HDL cholesterol. Science 2004; 305:869-872. (Pubitemid 39038422)
-
(2004)
Science
, vol.305
, Issue.5685
, pp. 869-872
-
-
Cohen, J.C.1
Kiss, R.S.2
Pertsemlidis, A.3
Marcel, Y.L.4
McPherson, R.5
Hobbs, H.H.6
-
11
-
-
32444441330
-
Multiple rare variants in NPC1L1 associated with reduced sterol absorption and plasma low-density lipoprotein levels
-
DOI 10.1073/pnas.0508483103
-
Cohen JC, Pertsemlidis A, Fahmi S, et al. Multiple rare variants in NPC1L1 associated with reduced sterol absorption and plasma low-density lipoprotein levels. Proc Natl Acad Sci U S A 2006; 103:1810-1815. (Pubitemid 43228775)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.6
, pp. 1810-1815
-
-
Cohen, J.C.1
Pertsemlidis, A.2
Fahmi, S.3
Esmail, S.4
Vega, G.L.5
Grundy, S.M.6
Hobbs, H.H.7
-
12
-
-
65249186429
-
Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans
-
Edmondson AC, Brown RJ, Kathiresan S, et al. Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans. J Clin Invest 2009; 119:1042-1050.
-
(2009)
J Clin Invest
, vol.119
, pp. 1042-1050
-
-
Edmondson, A.C.1
Brown, R.J.2
Kathiresan, S.3
-
13
-
-
46249103255
-
Functional characterization of genetic variants in NPC1L1 supports the sequencing extremes strategy to identify complex trait genes
-
DOI 10.1093/hmg/ddn108
-
Fahmi S, Yang C, Esmail S, et al. Functional characterization of genetic variants in NPC1L1 supports the sequencing extremes strategy to identify complex trait genes. Hum Mol Genet 2008; 17:2101-2107. (Pubitemid 351911979)
-
(2008)
Human Molecular Genetics
, vol.17
, Issue.14
, pp. 2101-2107
-
-
Fahmi, S.1
Yang, C.2
Esmail, S.3
Hobbs, H.H.4
Cohen, J.C.5
-
14
-
-
41649098656
-
Cardiovascular disease risk prediction using genetic information (gene scores): Is it really informative?
-
DOI 10.1097/MOL.0b013e3282f5283e, PII 0004143320080400000006
-
Humphries SE, Yiannakouris N, Talmud PJ. Cardiovascular disease risk prediction using genetic information (gene scores): is it really informative? Curr Opin Lipidol 2008; 19:128-132. (Pubitemid 351483299)
-
(2008)
Current Opinion in Lipidology
, vol.19
, Issue.2
, pp. 128-132
-
-
Humphries, S.E.1
Yiannakouris, N.2
Talmud, P.J.3
-
15
-
-
40949149395
-
Polymorphisms associated with cholesterol and risk of cardiovascular events
-
DOI 10.1056/NEJMoa0706728
-
Kathiresan S, Melander O, Anevski D, et al. Polymorphisms associated with cholesterol and risk of cardiovascular events. N Engl J Med 2008; 358:1240-1249. (Pubitemid 351439225)
-
(2008)
New England Journal of Medicine
, vol.358
, Issue.12
, pp. 1240-1249
-
-
Kathiresan, S.1
Melander, O.2
Anevski, D.3
Guiducci, C.4
Burtt, N.P.5
Roos, C.6
Hirschhorn, J.N.7
Berglund, G.8
Hedblad, B.9
Groop, L.10
Altshuler, D.M.11
Newton-Cheh, C.12
Orho-Melander, M.13
-
16
-
-
43049135919
-
Evaluation of a variant in the transcription factor 7-like 2 (TCF7L2) gene and prostate cancer risk in a population-based study
-
DOI 10.1002/pros.20732
-
Agalliu I, Suuriniemi M, Prokunina-Olsson L, et al. Evaluation of a variant in the transcription factor 7-like 2 (TCF7L2) gene and prostate cancer risk in a population-based study. Prostate 2008; 68:740-747. (Pubitemid 351632945)
-
(2008)
Prostate
, vol.68
, Issue.7
, pp. 740-747
-
-
Agalliu, I.1
Suuriniemi, M.2
Prokunina-Olsson, L.3
Johanneson, B.4
Collins, F.S.5
Stanford, J.L.6
Ostrander, E.A.7
-
17
-
-
58949097704
-
Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship
-
Anderson CA, Massey DC, Barrett JC, et al. Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship. Gastroenterology 2009; 136:523.e3-529.e3.
-
(2009)
Gastroenterology
, vol.136
-
-
Anderson, C.A.1
Massey, D.C.2
Barrett, J.C.3
-
18
-
-
39749118602
-
Multiple loci identified in a genome-wide association study of prostate cancer
-
DOI 10.1038/ng.91, PII NG91
-
Thomas G, Jacobs KB, Yeager M, et al. Multiple loci identified in a genome-wide association study of prostate cancer. Nat Genet 2008; 40:310-315. (Pubitemid 351311773)
-
(2008)
Nature Genetics
, vol.40
, Issue.3
, pp. 310-315
-
-
Thomas, G.1
Jacobs, K.B.2
Yeager, M.3
Kraft, P.4
Wacholder, S.5
Orr, N.6
Yu, K.7
Chatterjee, N.8
Welch, R.9
Hutchinson, A.10
Crenshaw, A.11
Cancel-Tassin, G.12
Staats, B.J.13
Wang, Z.14
Gonzalez-Bosquet, J.15
Fang, J.16
Deng, X.17
Berndt, S.I.18
Calle, E.E.19
Feigelson, H.S.20
Thun, M.J.21
Rodriguez, C.22
Albanes, D.23
Virtamo, J.24
Weinstein, S.25
Schumacher, F.R.26
Giovannucci, E.27
Willett, W.C.28
Cussenot, O.29
Valeri, A.30
Andriole, G.L.31
Crawford, E.D.32
Tucker, M.33
Gerhard, D.S.34
Fraumeni Jr., J.F.35
Hoover, R.36
Hayes, R.B.37
Hunter, D.J.38
Chanock, S.J.39
more..
|