Elastase, α1-proteinase inhibitor, and interleukin-8 in pre-dialyzed and hemodialyzed patients with chronic kidney disease

Pediatrics International

Volumn 52, Issue 5, 2010, Pages 735-743

  Polańska, Bozena ^a   Augustyniak, Daria ^b   Makulska, Irena ^a   Niemczuk, Maria ^a   Zwolińska, Danuta ^a   Jankowski, Adam ^a,b  

^a WROCLAW MEDICAL UNIVERSITY   (Poland)

^b UNIVERSITY OF WROC AW   (Poland)

Author keywords

1 proteinase inhibitor; chronic kidney disease; elastase; hemodialysis; interleukin 8

Indexed keywords

ALPHA 1 ANTITRYPSIN; ELASTASE; INTERLEUKIN 8;

ADOLESCENT; ADULT; ARTICLE; CHILD; CHRONIC KIDNEY DISEASE; CLINICAL ARTICLE; CONSERVATIVE TREATMENT; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HEMODIALYSIS; HUMAN; IMMUNODIFFUSION; INFLAMMATION; LEUKOCYTE ACTIVATION; MALE; PRIORITY JOURNAL; PROTEIN DETERMINATION;

ADOLESCENT; ADULT; AGE FACTORS; ALPHA 1-ANTITRYPSIN; CASE-CONTROL STUDIES; CHILD; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKIN-8; KIDNEY FUNCTION TESTS; LEUKOCYTE ELASTASE; MALE; MIDDLE AGED; PROGNOSIS; REFERENCE VALUES; RENAL DIALYSIS; RENAL INSUFFICIENCY, CHRONIC; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX; SEX FACTORS; STATISTICS, NONPARAMETRIC; YOUNG ADULT;

EID: 77957357773     PISSN: 13288067     EISSN: 1442200X     Source Type: Journal    
DOI: 10.1111/j.1442-200X.2010.03162.x     Document Type: Article

References (45)

1. Sarnak MJ, Jaber BL. Mortality caused by sepsis in patients with end-stage renal disease compared with the general population. Kidney Int. 2000 58 : 1758 1764.
2. Panichi V, Taccola D, Rizza GM et al. Interleukin-8 is a powerful prognostic predictor of all-cause and cardiovascular mortality in dialytic patients. Nephron Clin. Pract. 2006 102 : c51 8.
3. Yao Q, Axelsson J, Heimburger O, Stenvinkel P, Lindholm B. Systemic inflammation in dialysis patients with end-stage renal disease: Causes and consequences. Minerva Urol. Nefrol. 2004 56 : 237 248. (Pubitemid 39222430)
4. Litwin M, Grenda R, Prokurat S et al. Patient survival and causes of death on hemodialysis and peritoneal dialysis: single-center study. Pediatr. Nephrol. 2001 16 : 996 1001.
5. Ece A, Gurkan F, Kervancioglu M et al. Oxidative stress, inflammation and early cardiovascular damage in children with chronic renal failure. Pediatr. Nephrol. 2006 21 : 545 552.
6. Lee WL, Downey GP. Leukocyte elastase: Physiological functions and role in acute lung injury. Am. J. Respir. Crit. Care Med. 2001 164 : 896 904.
7. Costa E, Rocha S, Rocha-Pereira P et al. Neutrophil activation and resistance to recombinant human erythropoietin therapy in hemodialysis patients. Am. J. Nephrol. 2008 28 : 935 940.
8. Morena M, Delbosc S, Dupuy AM, Canaud B, Cristol JP. Overproduction of reactive oxygen species in end-stage disease patients: A potential component of hemodialysis-associated inflammation. Hemodial. Int. 2005 9 : 37 46.
9. Zwolińska D, Grzeszczak W, Szczepańska M, Kiliś-Pstrusińska K, Szprynger K. Vitamins A, E and C as non-enzymatic antioxidants and their relation to lipid peroxidation in children with chronic renal failure. Nephron Clin. Pract. 2006 103 : c12 18.
10. Cowburn AS, Condliffe AM, Farahi N, Summers C, Chilvers ER. Advances in neutrophil biology: clinical implications. Chest 2008 134 : 606 612.
11. Stockley RA. Neutrophilic inflammation: "Don't you go to pieces on me!". Eur. Respir. J. 2006 28 : 257 258.
12. Baggiolini M, Walz A, Kunkel SL. Neutrophil-activating peptide-1/interleukin-8, a novel cytokine that activates neutrophils. J. Clin. Investig. 1989 84 : 1045 1049.
13. Segura RM, Alegre J, Varela E et al. Interleukin-8 and markers of neutrophil degranulation in pleural effusions. Am. J. Respir. Crit. Care Med. 1998 157 : 1565 1572.
14. Baggiolini M, Clark-Lewis I. Interleukin-8, a chemotactic and inflammatory cytokine. FEBS Lett. 1992 307 : 97 101.
15. Donovan KL, Davies M, Coles GA, Williams JD. Relative roles of elastase and reactive oxygen species in the degradation of human glomerular basement membrane by intact human neutrophils. Kidney Int. 1994 45 : 1555 1561.
16. 1-protease inhibitor. Am. J. Respir. Cell Mol. Biol. 2005 32 : 553 559.
17. 1-proteinase inhibitor and human leukocyte elastase is a neutrophil chemoattractant. J. Exp. Med. 1988 167 : 1608 1615.
18. Polańska B, Zwolińska D, Mader I. Usefulness of neutrophil elastase α1-proteinase complex determination in children with idiopathic nephritic syndrome. Pediatr. Pol. 1999 74 : 355 361.
19. Fretzayas A, Moustaki M, Gourgiotis D, Bossios A, Koukoutsakis P, Stavrinadis C. Polymorphonuclear elastase as a diagnostic marker of acute pyelonephritis in children. Pediatrics. 2000 105 : e28 doi: 10.1542/peds.105.2. e28).
20. Anding K, Gross P, Rost JM, Allgaier D, Jacobs E. The influence of uraemia and haemodialysis on neutrophil phagocytosis and antimicrobial killing. Nephrol. Dial. Transplant. 2003 18 : 2067 2073.
21. Sardenberg C, Suassuna P, Andreoli MC et al. Effects of uraemia and dialysis modality on polymorphonuclear cell apoptosis and function. Nephrol Dial. Transplant. 2006 21 : 160 165.
22. Knudsen F, Nielsen AH, Pedersen JO, Jersild C. On the kinetics of complement activation, leukopenia and granulocyte-elastase release induced by haemodialysis. Scand. J. Clin. Lab. Invest. 1985 45 : 759 766. (Pubitemid 16235901)
23. Heidland A, Hörl WH, Heller N, Heine H, Neumann S, Heidbreder E. Release of granulocyte neutral proteinases in patients with acute and chronic renal failure. Adv. Exp. Med. Biol. 1984 167 : 417 431.
24. Hörl WH, Jochum M, Heidland A, Fritz H. Release of granulocyte proteinases during hemodialysis. Am. J. Nephrol. 1983 3 : 213 217.
25. Nairn J, Hodge G, Henning P. Changes in leukocyte subsets: Clinical implications for children with chronic renal failure. Pediatr. Nephrol. 2005 20 : 190 196.
26. Heidland A, Hörl WH, Heller N, Heine H, Neumann S, Heidbreder E. Proteolytic enzymes and catabolism: Enhanced release of granulocyte proteinases in uremic intoxication and during hemodialysis. Kidney Int. 1983 24 (Suppl. 16 S27 36.
27. Ono K, Ueki K, Inose K, Tsuchida A, Yano S, Nojima Y. Plasma levels of myeloperoxidase and elastase are differentially regulated by hemodialysis membranes and anticoagulants. Res. Commun. Mol. Pathol. Pharmacol. 2000 108 : 341 349.
28. Pawlak K, Pawlak D, Myśliwiec M. Impaired renal function and duration of dialysis therapy are associated with oxidative stress and proatherogenic cytokine levels in patients with end-stage renal disease. Clin. Biochem. 2007 40 : 81 5.
29. Tremblay GM, Janelle MF, Bourbonnais Y. Anti-inflammatory activity of neutrophil elastase inhibitors. Curr. Opin. Investig. Drugs. 2003 4 : 556 565.
30. Sponer M, Nick HP, Schnebli HP. Different susceptibility of elastase inhibitors to inactivation by proteinases from Staphylococcus aureus and Pseudomonas aeruginosa. Biol. Chem. Hoppe Seyler 1991 372 : 963 970.
31. 1-proteinase inhibitor. J. Biol. Chem. 1991 266 : 15356 15362.
32. Brown RA, Lever R, Jones NA, Page CP. Effects of heparin and related molecules upon neutrophil aggregation and elastase release in vitro. Br. J. Pharmacol. 2003 139 : 845 853.
33. 1-antitrypsin in cystic fibrosis bronchopulmonary secretions. Pediatr. Pulmonol. 1989 7 : 12 17.
34. 1-antitrypsin in patients on hemodialysis. Clin. J. Am. Soc. Nephrol. 2009 4 : 142 151.
35. 1-antitrypsin but not complement C3 and C4 predicts chronic inflammation in hemodialysis patients. Ren Fail. 2003 25 : 589 593.
36. 1-protease inhibitor at the surface of human polymorphonuclear neutrophils. J. Immunol. 2005 175 : 3329 3338.
37. Owen CA, Campbell MA, Sannes PL, Boukedes SS, Campbell EJ. Cell surface-bound elastase and cathepsin G on human neutrophils: A novel, non-oxidative mechanism by which neutrophils focus and preserve catalytic activity of serine proteinases. J. Cell Biol. 1995 131 : 775 789.
38. Hayama T, Matsuyama M, Funao K et al. Beneficial effect of neutrophil elastase inhibitor on renal warm ischemia-reperfusion injury in the rat. Transplant. Proc. 2006 38 : 2201 2202.
39. Pereira BJG. Balance between pro-inflammatory cytokines and their specific inhibitors in patients on dialysis. Nephrol. Dial. Transplant. 1995 10 (Suppl. 7 27 32.
40. Goldstein SL, Leung JC, Silverstein DM. Pro- and anti-inflammatory cytokines in chronic pediatric dialysis patients: Effect of aspirin. Clin. J. Am. Soc. Nephrol. 2006 1 : 979 986.
41. Tarakçioglu M, Erbagci AB, Usalan C, Deveci R, Kocabaş R. Acute effect of hemodialysis on serum levels of the proinflammatory cytokines. Mediators Inflamm. 2003 12 : 15 19.
42. DeForge LE, Fantone JC, Kenney JS, Remick DG. Oxygen radical scavengers selectively inhibit interleukin-8 production in human whole blood. J. Clin. Invest. 1992 90 : 2123 2129.
43. Hörl WH, Riegel W, Steinhauer HB et al. Granulocyte activation during hemodialysis. Clin. Nephrol. 1986 26 (Suppl. 1 S30 4.
44. Hörl WH, Schaefer RM, Heidland A. Effect of different dialyzers on proteinases and proteinase inhibitors during hemodialysis. Am. J. Nephrol. 1985 5 : 320 326.
45. Rysz J, Banach M, Ciałkowska-Rysz A et al. Blood serum levels of IL-2, IL-6, IL-8, TNF-alpha and IL-1beta in patients on maintenance hemodialysis. Cell Mol. Immunol. 2006 3 : 151 154.