Fermentative metabolism by the human gut microbiota;Activités métaboliques du microbiote intestinal humain.

Gastroenterologie Clinique et Biologique

Volumn 34, Issue SUPPL. 1, 2010, Pages

  Bernalier Donadille, A ^a  

^a CEMAGREF   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; AMMONIA; CELLULOSE; HEMICELLULOSE; MUCIN; NITROGEN; PANCREAS ENZYME; POLYSACCHARIDE; PROTEINASE; PEPTIDE; PROTEIN;

AMINO ACID METABOLISM; ANAEROBIC BACTERIUM; ARTICLE; BACTEROIDES; BIFIDOBACTERIUM; BILE SECRETION; BIODEGRADATION; CARBOHYDRATE METABOLISM; CLOSTRIDIUM; DEAMINATION; DESQUAMATION; DIETARY FIBER; ENTEROCOCCUS; EPITHELIUM CELL; EUBACTERIUM; FERMENTATION; GASTROINTESTINAL ABSORPTION; GRAM POSITIVE BACTERIUM; HEALTH; HOMEOSTASIS; HOST; HUMAN; HYDROLYSIS; INTESTINE FLORA; LARGE INTESTINE; METABOLITE; NUTRITION; PROTEIN DEGRADATION; PROTEIN METABOLISM; ROSEBURIA; RUMINOCOCCUS; ALGORITHM; COLON; DIET; GASTROINTESTINAL TRACT; HEALTH STATUS; METABOLISM; METAGENOME; MICROBIOLOGY;

ALGORITHMS; COLON; DIET; DIETARY FIBER; FERMENTATION; GASTROINTESTINAL TRACT; HEALTH STATUS; HUMANS; METAGENOME; PEPTIDES; POLYSACCHARIDES; PROTEINS;

EID: 77957351543     PISSN: 03998320     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0399-8320(10)70016-6     Document Type: Article

References (31)

1. Flourié B., Florent C., Etanchaud F. Fonction digestive du caecum chez l'homme normal. Cah Nut Diet 1988, 23:111-115.
2. Macfarlane G.T., Cummings J.H. The colonic flora, fermentation and large bowel digestive function. The large intestine: physiology, pathophysiology, disease 1991, 51-92. Raven Press, NY. S.F. Phillips, J.H. Pemberton, R.G. Shorter (Eds.).
3. Englyst H.N., Hay S., Macfarlane G.T. Polysaccharides breakdown by mixed populations of human faecal bacteria. FEMS Microbiol Lett 1987, 45:163-171.
4. Flint H.J., Bayer E.A., Rincon M.T., Lamed R., White B.A. Polysaccharide utilization by gut bacteria: potential for new insights from genomic analysis. Nat Rev Microbiol 2008, 6:121-131.
5. Leitch E.C., Walker A.W., Duncan S.H., Holtrop G., Flint H.J. Selective colonization of insoluble substrates by human faecal bacteria. Environ Microbiol 2007, 9:667-679.
6. Walker A.W., Duncan S.H., Harmsen H.J., Holtrop G., Welling G.W., Flint H.J. The species composition of the human intestinal microbiota differs between particle-associated and liquid phase communities. Environ Microbiol 2008, 10:3275-3283.
7. McCarthy R.E., Salyers A.A. Evidence that polygalacturonic acid is not an important substrate for Bacteroides species in the colon. Appl Environ Microbiol 1986, 52:9-16.
8. Ramsay A.G., Scott K.P., Martin J.C., Rincon M.T., Flint H.J. Cell-associated α-amylases of butyrate-producing Firmicute bacteria from the human colon. Microbiology 2006, 152:3281-3290.
9. Robert C., Bernalier-Donadille A. The cellulolytic microflora of the human colon: evidence of microcrystalline cellulosedegrading bacteria in methane-excreting subjects. FEMS Microbiol Ecol 2003, 46:81-89.
10. Chassard C., Goumy V., Leclerc M., Del'homme C., Bernalier-Donadille A. Characterization of the xylan-degrading microbial community from human faeces. FEMS Microbiol Ecol 2007, 61:121-131.
11. Salyers A.A. Fermentation of polysaccharides by human colonic anaerobes. Dietary Fibre 1995, 29-35. John Libbey Eurotext, Paris. C. Cherbut, J.L. Barry, D. Lairon, M. Durand (Eds.).
12. 2-utilizing microorganisms from the human colon. FEMS Microbiol Lett 2001, 205:209-214.
13. 2-producing cellulolytic bacteria from the human colon. FEMS Microbiol Lett 2005, 242:339-344.
14. 2 and acetate transfers during xylan fermentation between a butyrate-producing xylanolytic species and hydrogenotrophic microorganisms from the human gut. FEMS Microbio Lett 2006, 254:116-122.
15. Bernalier-Donadille A. Main Metabolic functions of the human intestinal microflora. Gut Microflora: digestive physiology and pathology 2006, 61-80. John Libbey Eurotext, Paris. J.C. Rambaud, J.P. Buts, G. Corthier, B. Flourié (Eds.).
16. Flint H.J., Duncan S.H., Scott K.P., Louis P. Interactions and competition within the microbial community of the human colon: links between diet and health. Environ Microbiol 2007, 9:1101-1111.
17. Louis P., Scott K.P., Duncan S.H., Flint H.J. Understanding the effects of diet on bacterial metabolism in the large intestine. J Appl Microbiol 2007, 102:1197-1208.
18. Pryde S.E., Ducan S.H., Hold G.L., Stewart C.S., Flint H.J. The microbiology of butyrate formation in the human colon. FEMS Microbiol Lett 2002, 217:133-139.
19. Barcenilla A., Pryde S.E., Martin J.C., Duncan S.H., Stewart C.S., Henderson C., et al. Phylogenetic relationship of butyrateproducing bacteria from the human gut. Appl Environ Microbiol 2000, 72:3593-3599.
20. Hold G.L., Schwiertz A., Aminov R.I., Blaut M., Flint H.J. Oligonucleotide probes that detect quantitatively significant groups of butyrate-producing bacteria in human feces. Appl Environ Microbiol 2003, 69:4320-4324.
21. Aminov R.I., Walker A.W., Duncan S.H., Harmsen H.J., Welling G.W., Flint H.J. Molecular diversity, cultivation and improved detection by fluorescent in situ hybridization of a dominant group of human gut bacteria related to Roseburia spp. or Eubacterium rectale. Appl Environ Microbiol 2006, 72:6371-6376.
22. Duncan S.H., Barcenilla A., Stewart C.S., Pryde S.E., Flint H.J. Acetate uilization and butyryl coenzyme A (CoA): acetate-CoA transferase in butyrate-producing bacteria from the human large intestine. Appl Environ Microbiol 2002, 68:5186-5190.
23. Louis P., Flint H.J. Diversity, metabolism and microbial ecology of butyrate-producing bacteria from the human large intestine. FEMS Microbiol Lett 2009, 294:1-8.
24. Bourriaud C., Robins R.J., Martin L., Kozlowski F., Tenailleau E., Cherbut C., et al. Lactate is mainly fermented to butyrate by human intestinal microfloras but inter-individual variation is evident. J Appl Microbiol 2005, 99:201-212.
25. Chassard C., Scott K.P., Marquet P., Martin J.C., Del'homme C., Dapoigny M., et al. Assessment of metabolic diversity within the intestinal microbiota from healthy humans using combined molecular and cultural approaches. FEMS Microbiol Ecol 2008, 66:496-504.
26. Duncan S.H., Louis P., Flint H.J. Lactate-utilizing bacteria, isolated from human feces, that produce butyrate as a major fermentation product. Appl Environ Microbiol 2004, 70:5810-5817.
27. 13C] lactate in the rumen of dairy cattle. Appl Environ Microbiol 1981, 42:649-655.
28. Gibson G.R., Cummings J.H., Macfarlane G.T., Allison C., Segal I., Vorster H.H., et al. Alternative pathways for hydrogen disposal during fermentation in the human colon. Gut 1990, 31:679-683.
29. Marquet P., Duncan S.H., Chassard C., Bernalier-Donadille A., Flint H.J. Lactate has the potential to promote hydrogen sulphide formation in the human colon. FEMS Microbiol Lett 2009, 299:128-134.
30. Cummings J.H., Macfarlane G.T. The control and consequence of bacterial fermentation in the human colon. J Appl Bacteriol 1991, 70:443-459.
31. Macfarlane G.T., Gibson G.R. Metabolic activities of the normal colonic flora. Human Health. The contribution of microorganisms 1994, 17-52. Springer-Verlag, Londres. S.A.W.W. Gibson (Ed.).