A quality management systems approach for CD4 testing in resource-poor settings

American Journal of Clinical Pathology

Volumn 134, Issue 4, 2010, Pages 556-567

  Westerman, Larry E ^a   Kohatsu, Luciana ^a   Ortiz, Astrid ^a   McClain, Bernice ^a   Kaplan, Jonathan ^a   Spira, Thomas ^a   Marston, Barbara ^a   Jani, Ilesh V ^b   Nkengasong, John ^a   Parsons, Linda M ^a  

^a CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^b Institut Nacional da Saude   (Mozambique)

Author keywords

AIDS; CD4 testing; HIV; Laboratory

Indexed keywords

REAGENT; ANTIRETROVIRUS AGENT;

BLOOD SAMPLING; CD4+ T LYMPHOCYTE; CLINICAL COMPETENCE; CLINICAL LABORATORY; CONFERENCE PAPER; DIAGNOSTIC ACCURACY; EQUIPMENT; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MEDICAL DOCUMENTATION; PRIORITY JOURNAL; QUALITY CONTROL; SAFETY; STORAGE; TOTAL QUALITY MANAGEMENT; TRAINING; ACQUIRED IMMUNODEFICIENCY SYNDROME; CD4 LYMPHOCYTE COUNT; DEVICES; DIAGNOSTIC PROCEDURE; EDUCATION; HEALTH CARE QUALITY; HOSPITAL SERVICE; LABORATORY; LABORATORY DIAGNOSIS; LABORATORY PERSONNEL; POVERTY; PROCEDURES; STANDARDS;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ANTI-RETROVIRAL AGENTS; CD4 LYMPHOCYTE COUNT; CLINICAL LABORATORY TECHNIQUES; HUMANS; LABORATORIES; MAINTENANCE; MEDICAL LABORATORY PERSONNEL; POVERTY; QUALITY ASSURANCE, HEALTH CARE; SPECIMEN HANDLING;

EID: 77957347552     PISSN: 00029173     EISSN: 19437722     Source Type: Journal    
DOI: 10.1309/AJCPP7MCHFYLX2FM     Document Type: Conference Paper

References (18)

1. Department of Health and Human Services Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents. 2008:1-139. http://aidsinfo.nih.gov/contentfiles/AdultandAdolescentGL.pdf. Accessed October 16, 2009.
2. Walensky RP, Wolf LL, Wood R, et al; for the CEPAS (Cost-Effectiveness of Preventing AIDS Complication)- International Investigators. When to start antiretroviral therapy in resource-limited settings. Ann Intern Med. 2009;151:157-166.
3. World Health Organization. HIV technical briefs: adult ARV treatment guidelines (2006 version). Updated May 28, 2007. http://www.who.int/hiv/pub/ toolkits/ART%20Technical%20Update%2028%20May%2007.pdf. Accessed October 16, 2009.
4. Gilks CF, Crowley S, Ekpini R, et al. The WHO public-health approach to antiretroviral treatment against HIV in resource-limited settings. Lancet. 2006;368:505-510. (Pubitemid 44142772)
5. World Health Organization. Rapid advice: antiretroviral therapy of HIV infection in adults and adolescents. November 2009. http://www.who.int/hiv/ topics/treatment/revisions/en/index.html. Accessed December 21, 2009.
6. Peter T, Badrichani A, Wu E, et al. Challenges in implementing CD4 testing in resource-limited settings. Cytometry B Clin Cytom. 2008;74B(suppl 1):S123-S130. (Pubitemid 351569280)
7. Birx D, deSouza M, Nkengasong JN. Laboratory challenges in the scaling up of HIV, TB, and malaria programs: the interaction of health and laboratory systems, clinical research, and service delivery. Am J Clin Pathol. 2009;131:849-851.
8. Vitoria M, Granich R, Gilks CF, et al. The global fight against HIV/AIDS, tuberculosis, and malaria: current status and future perspectives. Am J Clin Pathol. 2009;131:844-848.
9. Peter TF, Shimada Y, Freeman RR, et al. The need for standardization in laboratory networks. Am J Clin Pathol. 2009;131:867-874.
10. Stevens W, Gelman R, Glencross DK, et al. Evaluating new CD4 enumeration technologies for resource-constrained countries. Nat Rev Microbiol. 2008;6(suppl):S29-S38.
11. Glencross DK, Janossy G, Coetzee LM, et al. Large-scale affordable PanLeucogated CD4 testing with proactive internal and external quality assessment: in support of the South African National Comprehensive Care, Treatment and Management Programme for HIV and AIDS. Cytometry B Clin Cytom. 2008;74B(suppl 1):S40-S51. (Pubitemid 351569271)
12. Mandy F, Janossy G, Bergeron M, et al. Affordable CD4 T-cell enumeration for resource-limited regions: a status report for 2008. Cytometry B Clin Cytom. 2008;74B(suppl 1):S27-S39. (Pubitemid 351569270)
13. Ruiz AR, Perez Fernandez I, Perea Baena JM, et al. Influence of sample storage time and temperature on lymphocyte subset counts using a FACSCount system [letter]. Haematologica. 2000;85:550-551.
14. Mergia A, O'Connell BO, Fishwild D, et al. Effect of blood storage temperature on absolute CD4 and CD8 counts. Presented as a poster at the 2004 Annual Meeting of the Clinical Cytometry Society; October 17-19, 2004; Long Beach, CA.
15. International Air Transport Association. Infectious substances shipping guidelines. http://www.iata.org/NR/rdonlyres/9C7E382B-2536-47CE-84B4- 9A883ECFA040/0/Guidance-Doc62DGR-50.pdf. Accessed October 16, 2009.
16. Westgard JO. QC: the calculations: Westgard QC. http://www.westgard.com/ qc-the-calculations/pdf.htm. Accessed October 17, 2009.
17. Glencross DK, Aggett HM, Stevens WS, et al. African regional external quality assessment for CD4 T-cell enumeration: development, outcomes, and performance of laboratories. Cytometry B Clin Cytom. 2008;74B(suppl 1):S69-S79.
18. Centers for Disease Control and Prevention. Guidelines for performing single-platform absolute CD4+ T-cell determinations with CD45 gating for persons infected with human immunodeficiency virus. MMWR Recomm Rep. 2003;52(RR-2):1-13.