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Volumn 46, Issue 10, 2010, Pages 705-711

Human papilloma virus in locally advanced stage III/IV squamous cell cancer of the oropharynx and impact on choice of therapy

Author keywords

Chemoradiotherapy; Clinical trials; Human papillomavirus; Locally advanced; Oral oncology; Oropharyngeal cancer

Indexed keywords

CARBOPLATIN; CETUXIMAB; CISPLATIN; DOCETAXEL; FLUOROURACIL; FOLINIC ACID; NIMORAZOLE; PACLITAXEL; PLACEBO; TIRAPAZAMINE; VORINOSTAT;

EID: 77957344295     PISSN: 13688375     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2010.07.006     Document Type: Review
Times cited : (20)

References (52)
  • 1
    • 0031964379 scopus 로고    scopus 로고
    • Etiological involvement of oncogenic human papillomavirus in tonsillar squamous cell carcinomas lacking retinoblastoma cell cycle control
    • T. Andl, T. Kahn, and A. Pfuhl Etiological involvement of oncogenic human papillomavirus in tonsillar squamous cell carcinomas lacking retinoblastoma cell cycle control Cancer Res 58 1998 5 13
    • (1998) Cancer Res , vol.58 , pp. 5-13
    • Andl, T.1    Kahn, T.2    Pfuhl, A.3
  • 2
    • 0034600339 scopus 로고    scopus 로고
    • Evidence for a causal association between human papillomavirus and a subset of head and neck cancers
    • M.L. Gillison, W.M. Koch, and R.B. Capone Evidence for a causal association between human papillomavirus and a subset of head and neck cancers J Natl Cancer Inst 92 2000 709 720
    • (2000) J Natl Cancer Inst , vol.92 , pp. 709-720
    • Gillison, M.L.1    Koch, W.M.2    Capone, R.B.3
  • 4
    • 34248350674 scopus 로고    scopus 로고
    • Case-control study of human papillomavirus and oropharyngeal cancer
    • G. D'Souza, A.R. Kreimer, and R. Viscidi Case-control study of human papillomavirus and oropharyngeal cancer N Engl J Med 356 2007 1944 1956
    • (2007) N Engl J Med , vol.356 , pp. 1944-1956
    • D'Souza, G.1    Kreimer, A.R.2    Viscidi, R.3
  • 5
    • 33644849030 scopus 로고    scopus 로고
    • Molecular classification identifies a subset of human papillomavirus-associated oropharyngeal cancers with favorable prognosis
    • P.M. Weinberger, Z. Yu, and B.G. Haffty Molecular classification identifies a subset of human papillomavirus-associated oropharyngeal cancers with favorable prognosis J Clin Oncol 24 2006 736 747
    • (2006) J Clin Oncol , vol.24 , pp. 736-747
    • Weinberger, P.M.1    Yu, Z.2    Haffty, B.G.3
  • 6
    • 0035575774 scopus 로고    scopus 로고
    • Prevalence, distribution, and viral load of human papillomavirus 16 DNA in tonsillar carcinomas
    • J.P. Klussmann, S.J. Weissenborn, and U. Wieland Prevalence, distribution, and viral load of human papillomavirus 16 DNA in tonsillar carcinomas Cancer 92 2001 2875 2884
    • (2001) Cancer , vol.92 , pp. 2875-2884
    • Klussmann, J.P.1    Weissenborn, S.J.2    Wieland, U.3
  • 7
    • 39149104081 scopus 로고    scopus 로고
    • Incidence trends for human papillomavirus-related and -unrelated oral squamous cell carcinomas in the United States
    • A.K. Chaturvedi, E.A. Engels, W.F. Anderson, and M.L. Gillison Incidence trends for human papillomavirus-related and -unrelated oral squamous cell carcinomas in the United States J Clin Oncol 26 2008 612 619
    • (2008) J Clin Oncol , vol.26 , pp. 612-619
    • Chaturvedi, A.K.1    Engels, E.A.2    Anderson, W.F.3    Gillison, M.L.4
  • 8
    • 34548297669 scopus 로고    scopus 로고
    • The incidence of tonsillar cancer in Sweden is increasing
    • L. Hammarstedt, H. Dahlstrand, and D. Lindquist The incidence of tonsillar cancer in Sweden is increasing Acta Otolaryngol 127 2007 988 992
    • (2007) Acta Otolaryngol , vol.127 , pp. 988-992
    • Hammarstedt, L.1    Dahlstrand, H.2    Lindquist, D.3
  • 9
    • 77955282693 scopus 로고    scopus 로고
    • HPV-associated head and neck cancer: A virus-related cancer epidemic
    • May 5. [Epub ahead of print]
    • Marur S, D'Souza G, Westra WH, Forastiere AA. HPV-associated head and neck cancer: a virus-related cancer epidemic. Lancet Oncol 2010 May 5. [Epub ahead of print].
    • (2010) Lancet Oncol
    • Marur, S.1    D'Souza, G.2    Westra, W.H.3    Forastiere, A.A.4
  • 10
    • 85047700479 scopus 로고    scopus 로고
    • Involvement of intact HPV16 E6/E7 gene expression in head and neck cancers with unaltered p53 status and perturbed pRb cell cycle control
    • T. Wiest, E. Schwarz, C. Enders, C. Flechtenmacher, and F.X. Bosch Involvement of intact HPV16 E6/E7 gene expression in head and neck cancers with unaltered p53 status and perturbed pRb cell cycle control Oncogene 21 2002 1510 1517
    • (2002) Oncogene , vol.21 , pp. 1510-1517
    • Wiest, T.1    Schwarz, E.2    Enders, C.3    Flechtenmacher, C.4    Bosch, F.X.5
  • 11
    • 0642286494 scopus 로고    scopus 로고
    • Centrosome abnormalities and genomic instability induced by human papillomavirus oncoproteins
    • S. Duensing, and K. Münger Centrosome abnormalities and genomic instability induced by human papillomavirus oncoproteins Prog Cell Cycle Res 5 2003 383 391
    • (2003) Prog Cell Cycle Res , vol.5 , pp. 383-391
    • Duensing, S.1    Münger, K.2
  • 12
    • 34548819077 scopus 로고    scopus 로고
    • Human papillomavirus and oropharyngeal cancer. Author reply
    • M. Gillison Human papillomavirus and oropharyngeal cancer. Author reply N Engl J Med 357 2007 1157 1158
    • (2007) N Engl J Med , vol.357 , pp. 1157-1158
    • Gillison, M.1
  • 13
    • 0025900477 scopus 로고
    • Human papillomavirus type 16 immortalized cervical keratinocytes contain transcripts encoding E6, E7, and E2 initiated at the P97 promoter and express high levels of E7
    • M. Nasseri, J.R. Gage, A. Lorincz, and F.O. Wettstein Human papillomavirus type 16 immortalized cervical keratinocytes contain transcripts encoding E6, E7, and E2 initiated at the P97 promoter and express high levels of E7 Virology 184 1991 131 140
    • (1991) Virology , vol.184 , pp. 131-140
    • Nasseri, M.1    Gage, J.R.2    Lorincz, A.3    Wettstein, F.O.4
  • 14
    • 0026425686 scopus 로고
    • Role of the human papillomaviruses in human cancer
    • P.M. Howley Role of the human papillomaviruses in human cancer Cancer Res 51 18 Suppl. 1991 5019s 5022s
    • (1991) Cancer Res , vol.51 , Issue.18 SUPPL.
    • Howley, P.M.1
  • 15
    • 0024412885 scopus 로고
    • Continued expression of HPV-16 E7 protein is required for maintenance of the transformed phenotype of cells co-transformed by HPV-16 plus EJ- ras
    • T. Crook, J.P. Morgenstern, L. Crawford, and L. Banks Continued expression of HPV-16 E7 protein is required for maintenance of the transformed phenotype of cells co-transformed by HPV-16 plus EJ- ras EMBO J 8 1989 513 519
    • (1989) EMBO J , vol.8 , pp. 513-519
    • Crook, T.1    Morgenstern, J.P.2    Crawford, L.3    Banks, L.4
  • 16
    • 77953815901 scopus 로고    scopus 로고
    • INK4a overexpression predicts translational active human papillomavirus infection in tonsillar cancer
    • Jan 20 [Epub ahead of print]
    • INK4a overexpression predicts translational active human papillomavirus infection in tonsillar cancer. Int J Cancer 2010 Jan 20 [Epub ahead of print].
    • (2010) Int J Cancer
    • Hoffmann, M.1    Ihloff, A.S.2    Görögh, T.3
  • 17
    • 77953450510 scopus 로고    scopus 로고
    • HPV & head and neck cancer: A descriptive update
    • P.K. Goon, M.A. Stanley, and J. Ebmeyer HPV & head and neck cancer: a descriptive update Head Neck Oncol 1 2009 36
    • (2009) Head Neck Oncol , vol.1 , pp. 36
    • Goon, P.K.1    Stanley, M.A.2    Ebmeyer, J.3
  • 18
    • 34247331367 scopus 로고    scopus 로고
    • High-risk human papillomavirus affects prognosis in patients with surgically treated oropharyngeal squamous cell carcinoma
    • L. Licitra, F. Perrone, and P. Bossi High-risk human papillomavirus affects prognosis in patients with surgically treated oropharyngeal squamous cell carcinoma J Clin Oncol 24 2006 5630 5636
    • (2006) J Clin Oncol , vol.24 , pp. 5630-5636
    • Licitra, L.1    Perrone, F.2    Bossi, P.3
  • 19
    • 33947140297 scopus 로고    scopus 로고
    • Combined analysis of HPV-DNA, p16 and EGFR expression to predict prognosis in oropharyngeal cancer
    • N. Reimers, H.U. Kasper, and S.J. Weissenborn Combined analysis of HPV-DNA, p16 and EGFR expression to predict prognosis in oropharyngeal cancer Int J Cancer 120 2007 1731 1738
    • (2007) Int J Cancer , vol.120 , pp. 1731-1738
    • Reimers, N.1    Kasper, H.U.2    Weissenborn, S.J.3
  • 20
    • 77449138742 scopus 로고    scopus 로고
    • Head and neck squamous cell cancer and the human papillomavirus: Summary of a National Cancer Institute State of the Science Meeting
    • November 9-10, Washington, DC
    • Adelstein DJ, Ridge JA, Gillison ML, et al. Head and neck squamous cell cancer and the human papillomavirus: summary of a National Cancer Institute State of the Science Meeting, November 9-10, 2008, Washington, DC, Head Neck, vol. 31; 2009. p. 1393-1422.
    • (2008) Head Neck , vol.31 , pp. 1393-1422
    • Adelstein, D.J.1    Ridge, J.A.2    Gillison, M.L.3
  • 21
    • 66549089889 scopus 로고    scopus 로고
    • Squamous cell carcinoma of the head and neck: ESMO clinical recommendations for diagnosis, treatment and follow up
    • L. Licitra, and E. Felip Squamous cell carcinoma of the head and neck: ESMO clinical recommendations for diagnosis, treatment and follow up Ann Oncol 20 Suppl. 4 2009 iv121 iv122
    • (2009) Ann Oncol , vol.20 , Issue.SUPPL. 4
    • Licitra, L.1    Felip, E.2
  • 23
    • 70350569994 scopus 로고    scopus 로고
    • Current trends in initial management of oropharyngeal cancer: The declining use of open surgery
    • M. Haigentz Jr., C.E. Silver, and J. Corry Current trends in initial management of oropharyngeal cancer: the declining use of open surgery Eur Arch Otorhinolaryngol 266 2009 1845 1855
    • (2009) Eur Arch Otorhinolaryngol , vol.266 , pp. 1845-1855
    • Haigentz Jr., M.1    Silver, C.E.2    Corry, J.3
  • 24
    • 0345647111 scopus 로고    scopus 로고
    • Surgery versus radiation therapy as single-modality treatment of tonsillar fossa carcinoma: The Roswell Park Cancer Institute experience (1971-1991)
    • W.L. Hicks Jr., M.A. Kuriakose, and T.R. Loree Surgery versus radiation therapy as single-modality treatment of tonsillar fossa carcinoma: The Roswell Park Cancer Institute experience (1971-1991) Laryngoscope 108 1998 1014 1019
    • (1998) Laryngoscope , vol.108 , pp. 1014-1019
    • Hicks Jr., W.L.1    Kuriakose, M.A.2    Loree, T.R.3
  • 25
    • 0033572407 scopus 로고    scopus 로고
    • Randomized trial of radiation therapy versus concomitant chemotherapy and radiation therapy for advanced-stage oropharynx carcinoma
    • G. Calais, M. Alfonsi, and E. Bardet Randomized trial of radiation therapy versus concomitant chemotherapy and radiation therapy for advanced-stage oropharynx carcinoma J Natl Cancer Inst 91 1999 2081 2086
    • (1999) J Natl Cancer Inst , vol.91 , pp. 2081-2086
    • Calais, G.1    Alfonsi, M.2    Bardet, E.3
  • 26
    • 3042701812 scopus 로고    scopus 로고
    • Final results of the 94-01 French head and neck oncology and radiotherapy group randomized trial comparing radiotherapy alone with concomitant radiochemotherapy in advanced-stage oropharynx carcinoma
    • F. Denis, P. Garaud, and E. Bardet Final results of the 94-01 French head and neck oncology and radiotherapy group randomized trial comparing radiotherapy alone with concomitant radiochemotherapy in advanced-stage oropharynx carcinoma J Clin Oncol 22 2004 69 76
    • (2004) J Clin Oncol , vol.22 , pp. 69-76
    • Denis, F.1    Garaud, P.2    Bardet, E.3
  • 29
    • 2342517421 scopus 로고    scopus 로고
    • Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck
    • J.S. Cooper, T.F. Pajak, and A.A. Forastiere Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck N Engl J Med 350 2004 1937 1944
    • (2004) N Engl J Med , vol.350 , pp. 1937-1944
    • Cooper, J.S.1    Pajak, T.F.2    Forastiere, A.A.3
  • 30
    • 18944395784 scopus 로고    scopus 로고
    • State-of-the-art management of locally advanced head and neck cancer
    • T.Y. Seiwert, and E.E. Cohen State-of-the-art management of locally advanced head and neck cancer Br J Cancer 92 2005 1341 1348
    • (2005) Br J Cancer , vol.92 , pp. 1341-1348
    • Seiwert, T.Y.1    Cohen, E.E.2
  • 31
    • 60349109660 scopus 로고    scopus 로고
    • Surgical salvage of cancer of the oropharynx after chemoradiation
    • J.M. Bumpous Surgical salvage of cancer of the oropharynx after chemoradiation Curr Oncol Rep 11 2009 151 155
    • (2009) Curr Oncol Rep , vol.11 , pp. 151-155
    • Bumpous, J.M.1
  • 32
    • 0038503645 scopus 로고    scopus 로고
    • Studies in the quality of life of head and neck cancer patients: Results of a two-year longitudinal study and a comparative cross-sectional cross-cultural survey
    • R.P. Morton Studies in the quality of life of head and neck cancer patients: results of a two-year longitudinal study and a comparative cross-sectional cross-cultural survey Laryngoscope 113 2003 1091 1103
    • (2003) Laryngoscope , vol.113 , pp. 1091-1103
    • Morton, R.P.1
  • 34
    • 0032889741 scopus 로고    scopus 로고
    • A prospective study on quality of life of patients with cancer of the oral cavity or oropharynx treated with surgery with or without radiotherapy
    • A. de Graeff, J.R. de Leeuw, W.J. Ros, G.J. Hordijk, G.H. Blijham, and J.A. Winnubst A prospective study on quality of life of patients with cancer of the oral cavity or oropharynx treated with surgery with or without radiotherapy Oral Oncol 35 1999 27 32
    • (1999) Oral Oncol , vol.35 , pp. 27-32
    • De Graeff, A.1    De Leeuw, J.R.2    Ros, W.J.3    Hordijk, G.J.4    Blijham, G.H.5    Winnubst, J.A.6
  • 36
    • 70350033525 scopus 로고    scopus 로고
    • Long-term quality of life after treatment for locally advanced oropharyngeal carcinoma: Surgery and postoperative radiotherapy versus concurrent chemoradiation
    • P. Boscolo-Rizzo, M. Stellin, R. Fuson, C. Marchiori, A. Gava, and M.C. Da Mosto Long-term quality of life after treatment for locally advanced oropharyngeal carcinoma: surgery and postoperative radiotherapy versus concurrent chemoradiation Oral Oncol 45 2009 953 957
    • (2009) Oral Oncol , vol.45 , pp. 953-957
    • Boscolo-Rizzo, P.1    Stellin, M.2    Fuson, R.3    Marchiori, C.4    Gava, A.5    Da Mosto, M.C.6
  • 37
    • 49249135921 scopus 로고    scopus 로고
    • Chemoselection as a strategy for organ preservation in advanced oropharynx cancer: Response and survival positively associated with HPV16 copy number
    • F.P. Worden, B. Kumar, and Lee JS Wolf Chemoselection as a strategy for organ preservation in advanced oropharynx cancer: Response and survival positively associated with HPV16 copy number J Clin Oncol 26 2008 3138 3146
    • (2008) J Clin Oncol , vol.26 , pp. 3138-3146
    • Worden, F.P.1    Kumar, B.2    Wolf, L.J.3
  • 38
    • 49249095295 scopus 로고    scopus 로고
    • EGFR, p16, HPV titer, Bcl-xL and p53, sex, and smoking as indicators of response to therapy and survival in oropharyngeal cancer
    • B. Kumar, K.G. Cordell, and J.S. Lee EGFR, p16, HPV titer, Bcl-xL and p53, sex, and smoking as indicators of response to therapy and survival in oropharyngeal cancer J Clin Oncol 26 2008 3128 3137
    • (2008) J Clin Oncol , vol.26 , pp. 3128-3137
    • Kumar, B.1    Cordell, K.G.2    Lee, J.S.3
  • 39
    • 39649109915 scopus 로고    scopus 로고
    • Improved survival of patients with human papillomavirus-positive head and neck squamous cell carcinoma in a prospective clinical trial
    • C. Fakhry, W.H. Westra, and S. Li Improved survival of patients with human papillomavirus-positive head and neck squamous cell carcinoma in a prospective clinical trial J Natl Cancer Inst 100 2008 261 269
    • (2008) J Natl Cancer Inst , vol.100 , pp. 261-269
    • Fakhry, C.1    Westra, W.H.2    Li, S.3
  • 40
    • 67650079783 scopus 로고    scopus 로고
    • Human papillomavirus infection as a prognostic factor in oropharyngeal squamous cell carcinomas treated in a prospective phase II clinical trial
    • S. Jo, A. Juhasz, and K. Zhang Human papillomavirus infection as a prognostic factor in oropharyngeal squamous cell carcinomas treated in a prospective phase II clinical trial Anticancer Res 29 2009 1467 1474
    • (2009) Anticancer Res , vol.29 , pp. 1467-1474
    • Jo, S.1    Juhasz, A.2    Zhang, K.3
  • 41
    • 73949102962 scopus 로고    scopus 로고
    • Induction chemotherapy and cetuximab for locally advanced squamous cell carcinoma of the head and neck: Results from a phase II prospective trial
    • M.S. Kies, F.C. Holsinger, and J.J. Lee Induction chemotherapy and cetuximab for locally advanced squamous cell carcinoma of the head and neck: results from a phase II prospective trial J Clin Oncol 28 2010 8 14
    • (2010) J Clin Oncol , vol.28 , pp. 8-14
    • Kies, M.S.1    Holsinger, F.C.2    Lee, J.J.3
  • 42
    • 70449709569 scopus 로고    scopus 로고
    • Racial survival disparity in head and neck cancer results from low prevalence of human papillomavirus infection in black oropharyngeal cancer patients
    • K. Settle, M.R. Posner, and L.M. Schumaker Racial survival disparity in head and neck cancer results from low prevalence of human papillomavirus infection in black oropharyngeal cancer patients Cancer Prev Res (Phila Pa) 2 2009 776 781
    • (2009) Cancer Prev Res (Phila Pa) , vol.2 , pp. 776-781
    • Settle, K.1    Posner, M.R.2    Schumaker, L.M.3
  • 43
    • 63449100560 scopus 로고    scopus 로고
    • Trans-tasman radiation oncology group phase III study of tirapazamine, cisplatin and radiation versus cisplatin and radiation for advanced squamous cell carcinoma of the head and neck
    • D. Rischin, L. Peters, and B. O'Sullivan Trans-tasman radiation oncology group phase III study of tirapazamine, cisplatin and radiation versus cisplatin and radiation for advanced squamous cell carcinoma of the head and neck J Clin Oncol 26 15S 2008 [Abstract LBA6008]
    • (2008) J Clin Oncol , vol.26 , Issue.15 S
    • Rischin, D.1    Peters, L.2    O'Sullivan, B.3
  • 44
    • 77954190940 scopus 로고    scopus 로고
    • Human papillomavirus and survival of patients with oropharyngeal cancer
    • June 7. [Epub ahead of print]
    • Ang AK, Harris J, Wheeler R, et al. Human papillomavirus and survival of patients with oropharyngeal cancer. N Engl J Med 2010 June 7. [Epub ahead of print].
    • (2010) N Engl J Med
    • Ang, A.K.1    Harris, J.2    Wheeler, R.3
  • 46
    • 74549123751 scopus 로고    scopus 로고
    • HPV-associated p16-expression and response to hypoxic modification of radiotherapy in head and neck cancer
    • P. Lassen, J.G. Eriksen, and S. Hamilton-Dutoit HPV-associated p16-expression and response to hypoxic modification of radiotherapy in head and neck cancer Radiother Oncol 94 2010 30 35
    • (2010) Radiother Oncol , vol.94 , pp. 30-35
    • Lassen, P.1    Eriksen, J.G.2    Hamilton-Dutoit, S.3
  • 47
    • 76749164984 scopus 로고    scopus 로고
    • Tobacco use in human papillomavirus-positive advanced oropharynx cancer patients related to increased risk of distant metastases and tumor recurrence
    • J.H. Maxwell, B. Kumar, and F.Y. Feng Tobacco use in human papillomavirus-positive advanced oropharynx cancer patients related to increased risk of distant metastases and tumor recurrence Clin Cancer Res 16 2010 1226 1235
    • (2010) Clin Cancer Res , vol.16 , pp. 1226-1235
    • Maxwell, J.H.1    Kumar, B.2    Feng, F.Y.3
  • 48
    • 77954600968 scopus 로고    scopus 로고
    • Critical impact of radiotherapy protocol compliance and quality in the treatment of advanced head and neck cancer: Results from TROG 02 02
    • L.J. Peters, B. O'Sullivan, and J. Giralt Critical impact of radiotherapy protocol compliance and quality in the treatment of advanced head and neck cancer: results from TROG 02 02 J Clin Oncol 28 2010 2996 3001
    • (2010) J Clin Oncol , vol.28 , pp. 2996-3001
    • Peters, L.J.1    O'Sullivan, B.2    Giralt, J.3
  • 49
    • 0034688905 scopus 로고    scopus 로고
    • Clinical significance of p53 functional loss in squamous cell carcinoma of the oropharynx
    • A. Obata, M. Eura, and J. Sasaki Clinical significance of p53 functional loss in squamous cell carcinoma of the oropharynx Int J Cancer 89 2000 187 193
    • (2000) Int J Cancer , vol.89 , pp. 187-193
    • Obata, A.1    Eura, M.2    Sasaki, J.3
  • 50
    • 0031040705 scopus 로고    scopus 로고
    • Human papillomavirus E6 and E7 oncoproteins alter cell cycle progression but not radiosensitivity of carcinoma cells treated with low-dose-rate radiation
    • T.L. DeWeese, and J.C. Walsh Human papillomavirus E6 and E7 oncoproteins alter cell cycle progression but not radiosensitivity of carcinoma cells treated with low-dose-rate radiation Int J Radiat Oncol Biol Phys 37 1997 145 154
    • (1997) Int J Radiat Oncol Biol Phys , vol.37 , pp. 145-154
    • Deweese, T.L.1    Walsh, J.C.2
  • 51
    • 14844299843 scopus 로고    scopus 로고
    • Human papillomavirus-16 associated squamous cell carcinoma of the head and neck (SCCHN): A natural disease model provides insights into viral carcinogenesis
    • R.L. Ferris, I. Martinez, and N. Sirianni Human papillomavirus-16 associated squamous cell carcinoma of the head and neck (SCCHN): a natural disease model provides insights into viral carcinogenesis Eur J Cancer 41 2005 807 815
    • (2005) Eur J Cancer , vol.41 , pp. 807-815
    • Ferris, R.L.1    Martinez, I.2    Sirianni, N.3
  • 52
    • 34147178690 scopus 로고    scopus 로고
    • The epidermal growth factor receptor (EGFR) in head and neck cancer: Its role and treatment implications
    • M. Zimmermann, A. Zouhair, D. Azria, and M. Ozsahin The epidermal growth factor receptor (EGFR) in head and neck cancer: its role and treatment implications Radiat Oncol 1 2006 11
    • (2006) Radiat Oncol , vol.1 , pp. 11
    • Zimmermann, M.1    Zouhair, A.2    Azria, D.3    Ozsahin, M.4


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