Intestinal permeability assessed by 51Cr-EDTA in rats with CCl4-induced cirrhosis

Arquivos de Gastroenterologia

Volumn 47, Issue 2, 2010, Pages 188-192

  Ramos, Ana Regina L ^a   Matte, Ursula ^a   Goldani, Helena Ayako Sueno ^a   Oliveira, Osmar L M ^a   Vieira, Sandra Maria Gonçalves ^a   Da Silveira, Themis Reverbel ^a  

^a HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

Author keywords

Edetic acid; Intestinal absorption; Liver cirrhosis, experimental; Rats

Indexed keywords

CARBON TETRACHLORIDE; EDETATE CHROMIUM CR 51; INDOMETACIN; OLIVE OIL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASCITES; CONTROLLED STUDY; DIET RESTRICTION; ENTERITIS; EVALUATION; HISTOPATHOLOGY; INTESTINE MUCOSA PERMEABILITY; LIVER CIRRHOSIS; MALE; NONHUMAN; RAT; SINGLE DRUG DOSE; URINARY EXCRETION; URINE VOLUME;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CARBON TETRACHLORIDE; EDETIC ACID; INDOMETHACIN; INTESTINAL ABSORPTION; INTESTINES; LIVER CIRRHOSIS, EXPERIMENTAL; MALE; PERMEABILITY; RATS; RATS, WISTAR;

EID: 77957321989     PISSN: 00042803     EISSN: 16784219     Source Type: Journal    
DOI: 10.1590/S0004-28032010000200014     Document Type: Article

References (26)

1. Almeida J, Galhenage S, Yu J, Kurtovic J, Riordan S. Gut flora and bacterial translocation in chronic liver disease. World J Gastroenterol. 2006;12:1493-502.
2. Antony A, Dhillon AP, Nygard G, Hudson M, Piasecki C, Strong P, Trevethick MA, Clayton NM, Joradan CC, Pounder RE, Wakefield AJ. Early histological features of small intestinal injury induced by indomethacin. Aliment Pharmacol Ther. 1993;7:29-40.
3. Bedossa P, Poynard T. An algorithm for the grading of activity in chronic hepatitis C. Hepatology. 1996;24:289-93. (Pubitemid 26260021)
4. Bernardes-Silva CF, Damião AO, Sipahi AM, Laurindo FR, Iriya K, Lopasso FP, Buchpiguel CA, Lordello ML, Agostinho CL, Laudanna AA. Ursodeoxycholic acid ameliorates experimental ileitis counteracting intestinal barrier dysfunction and oxidative stress. Dig Dis Sci. 2004;49:1569-74.
5. 51Cr-EDTA in rats with experimentally induced enteropathy. Gut 1985;26:579-85.
6. Bjarnason I, Macpherson A, Hollander D. Intestinal permeability: an overview. Gastroenterology. 1995;108:1566-81.
7. Campillo B, Pernet P, Bories PN, Richardet JP, Devanlay M, Aussel C. Intestinal permeability in liver cirrhosis: relationship with severe septic complications. Eur J Gastroenterol Hepatol. 1999;11:755-9. (Pubitemid 29349020)
8. Castilla-Cortázar I, Pascual M, Urdaneta E, Pardo J, Puche Je, Vivas B, Díaz-Casares A, García M, Díaz-Sanchez M, Varela-Nieto I, Castilla A, González-Barón S. Jejunal microvilli atrophy and reduced nutrient transport in rats with advanced liver cirrhosis: improvement by insulin-like growth factor I. BMC Gastroenterol. 2004;4:12.
9. DeMeo MT, Mutlu EA, Keshavarzian A, Tobin MC. Intestinal permeation and gastrointestinal disease. J Clin Gastroenterol. 2002;34:385-96.
10. Farhadi A, Banan A, Fields J, Keshavarzian A. Intestinal barrier: an interface between health and disease. J Gastroenterol Hepatol. 2003;18:479-97.
11. Fernández-Martínez E, Pérez-Àlvarez V, Tsutsumi V, Shibayama M, Muriel P. Chronic bile duct obstruction induces changes in plasma and hepatic levels of cytokines and nitric oxide in the rat. Exp Toxicol Pathol. 2006;58:49-58. (Pubitemid 44093213)
12. Garcia-Tsao G. Bacterial translocation: cause or consequence of decompensation in cirrhosis? J Hepatol. 2001;34:150-5.
13. 4-induced cirrhosis model in rats. Exp Toxicol Pathol. 2007;58:331-7.
14. a edição. Washington D. C.: National Academy Press, 1996.
15. Kalaitzakis E, Johansson JE, Bjarnason I, Björnsson E. Intestinal permeability in cirrhotic patients with and without ascites. Scand J Gastroenterol. 2006;41:326-30.
16. Lorenzo-Zuñiga V, Rodriguez-Ortigosa CM, Bartoli R, Martinez-Chantar ML, Martinez-Peralta L, Pardo A, Ojanguren I, Quiroga J, Planas R, Prieto J. Insulin-like growth factor I improves intestinal barrier function in cirrhotic rats. Gut. 2006;55:1306-12.
17. Natarajan SK, Ramamoorthy P, Thomas S, Basivireddy J, Kang G, Ramachandran A, Pulimood AB, Balasubramanian KA. Intestinal mucosal alterations in rats with carbon tetrachloride-induced cirrhosis: changes in glycosylation and luminal bacteria. Hepatology. 2006;43:837-46.
18. Pascual S, Such J, Esteban A, Zapater P, Casellas JA, Aparicio JR, Girona E, Gutierrez A, Carnices F, Palazon JM, Sola-Vera J, Perez-Mateo M. Intestinal permeability is increased in patients with advanced cirrhosis. Hepatogastroenterology. 2003;50:1482-6.
19. Peeters M, Geypens B, Claus D, Nevens H, Ghoos Y, Verbeke G, Baert F, Vermeire S, Vlietinck R, Rutgeerts P. Clustering of increased small intestinal permeability in families with Crohn's disease. Gastroenterology. 1997;113:802-7.
20. Pérez-Paramo M, Muñoz J, Albillos A, Freile I, Portero F, Santos M, Ortiz- Berrocal J. Effect of propranolol on the factors promoting bacterial translocation in cirrhotic rats with ascites. Hepatology. 2000;31:43-8. (Pubitemid 30033687)
21. Proctor E, Chatamra K. High yield micronodular cirrhosis in the rat. Gastroenterology. 1982;83:1183-90.
22. Ramachandran A, Prabhu R, Thomas S, Reddy JB, Pulimmod A, Balasubramanian KA. Intestinal mucosal alterations in experimental cirrhosis in the rat: role of oxygen free radicals. Hepatology. 2002;35:622-9.
23. Rosa H, Parise ER, Paranhos FRL, Braga AL, Freitas ASO, Hidalgo AN, Mor MBL. Controlled production of cirrhosis in the rat. Arq Gastroenterol. 1991;28:39-43.
24. Such J, Guardiola JV, de Juan J, Casellas JA, Pascual S, Aparicio JR, Sola-Vera J, Perez-Mateo M. Ultrastructural characteristics of distal duodenum mucosa in patients with cirrhosis. Eur J Gastroenterol Hepatol. 2002;14:371-6. (Pubitemid 34439034)
25. Zhang S, Wang W, Ren W, Dai Q, He B, Zhou K. Effects of lactulose on intestinal endotoxin and bacterial translocation in cirrhotic rats. Chin Med J. 2003;116:767-71. (Pubitemid 36701867)
26. Zuckerman MJ, Menzies IS, Path FRC, Ho H, Gregory GG, Casner NA, Crane RS, Hernandez JA. Assessment of intestinal permeability and absorption in cirrhotic patients with ascites using combined sugar probes. Dig Dis Sci. 2004;49:621-6. (Pubitemid 38992551)