메뉴 건너뛰기




Volumn 80, Issue 2-3, 2010, Pages 155-165

Molecular profile and cellular characterization of human bone marrow mesenchymal stem cells: Donor influence on chondrogenesis

Author keywords

Bone marrow; Cartilage; Cell therapy; Chondrogenesis; Osteoarthritis

Indexed keywords

BETA1 INTEGRIN; ENDOGLIN; MESSENGER RNA; OCTAMER TRANSCRIPTION FACTOR 4; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2;

EID: 77957310167     PISSN: 03014681     EISSN: 14320436     Source Type: Journal    
DOI: 10.1016/j.diff.2010.06.001     Document Type: Article
Times cited : (25)

References (55)
  • 3
    • 69249105385 scopus 로고    scopus 로고
    • Differentiation of synovial CD-105+ human mesenchymal stem cells into chondrocyte-like cells through spheroid formation
    • Arufe M.C., De la Fuente A., Fuentes-Boquete I., De Toro F.J., Blanco F.J. Differentiation of synovial CD-105+ human mesenchymal stem cells into chondrocyte-like cells through spheroid formation. J. Cell. Biochem. 2009, 108:145-155.
    • (2009) J. Cell. Biochem. , vol.108 , pp. 145-155
    • Arufe, M.C.1    De la Fuente, A.2    Fuentes-Boquete, I.3    De Toro, F.J.4    Blanco, F.J.5
  • 4
    • 0141483387 scopus 로고    scopus 로고
    • Beta1 integrins regulate chondrocyte rotation, G1 progression, and cytokinesis
    • Aszodi A., Hunziker E.B., Brakebusch C., Fässler R. Beta1 integrins regulate chondrocyte rotation, G1 progression, and cytokinesis. Genes Dev. 2003, 17:2465-2479.
    • (2003) Genes Dev. , vol.17 , pp. 2465-2479
    • Aszodi, A.1    Hunziker, E.B.2    Brakebusch, C.3    Fässler, R.4
  • 5
    • 0031602467 scopus 로고    scopus 로고
    • Articular cartilage: degeneration and osteoarthritis, repair, regeneration, and transplantation
    • Buckwalter J.A., Mankin H.J. Articular cartilage: degeneration and osteoarthritis, repair, regeneration, and transplantation. Instr. Course Lect. 1998, 47:487-504.
    • (1998) Instr. Course Lect. , vol.47 , pp. 487-504
    • Buckwalter, J.A.1    Mankin, H.J.2
  • 6
    • 0034988303 scopus 로고    scopus 로고
    • Bone marrow stromal stem cells: nature, biology, and potential applications
    • Bianco P., Riminucci M., Gronthos S., Robey P.G. Bone marrow stromal stem cells: nature, biology, and potential applications. Stem Cells 2001, 19:180-192.
    • (2001) Stem Cells , vol.19 , pp. 180-192
    • Bianco, P.1    Riminucci, M.2    Gronthos, S.3    Robey, P.G.4
  • 7
    • 0033547347 scopus 로고    scopus 로고
    • The monoclonal antibody SH-2, raised against human mesenchymal stem cells, recognizes an epitope on endoglin (CD105)
    • Barry F.P., Boynton R.E., Haynesworth S.E., Murphy J.M., Zaia J. The monoclonal antibody SH-2, raised against human mesenchymal stem cells, recognizes an epitope on endoglin (CD105). Biochem. Biophys. Res. Commun. 1999, 265:134-139.
    • (1999) Biochem. Biophys. Res. Commun. , vol.265 , pp. 134-139
    • Barry, F.P.1    Boynton, R.E.2    Haynesworth, S.E.3    Murphy, J.M.4    Zaia, J.5
  • 8
    • 0027259431 scopus 로고
    • Identification and expression of two forms of the human transforming growth factor-beta-binding protein endoglin with distinct cytoplasmic regions
    • Bellon T., Corbi A., Lastres P., Cales C., Cebrian M., Vera S., Cheifetz S., Massague J., Letarte M., Bernabeu C. Identification and expression of two forms of the human transforming growth factor-beta-binding protein endoglin with distinct cytoplasmic regions. Eur. J. Immunol. 1993, 23:2340-2345.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 2340-2345
    • Bellon, T.1    Corbi, A.2    Lastres, P.3    Cales, C.4    Cebrian, M.5    Vera, S.6    Cheifetz, S.7    Massague, J.8    Letarte, M.9    Bernabeu, C.10
  • 9
    • 0033534572 scopus 로고    scopus 로고
    • Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily
    • Barbara N.P., Wrana J.L., Letarte M. Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily. J. Biol. Chem. 1999, 274:584-594.
    • (1999) J. Biol. Chem. , vol.274 , pp. 584-594
    • Barbara, N.P.1    Wrana, J.L.2    Letarte, M.3
  • 11
    • 0026646785 scopus 로고
    • Endoglin is a component of the transforming growth factor-beta receptor system in human endothelial cells
    • Cheifetz S., Bellón T., Calés C., Vera S., Bernabeu C., Massagué J., Letarte M. Endoglin is a component of the transforming growth factor-beta receptor system in human endothelial cells. J. Biol. Chem. 1992, 267:19027-19030.
    • (1992) J. Biol. Chem. , vol.267 , pp. 19027-19030
    • Cheifetz, S.1    Bellón, T.2    Calés, C.3    Vera, S.4    Bernabeu, C.5    Massagué, J.6    Letarte, M.7
  • 13
    • 64049106881 scopus 로고    scopus 로고
    • Integrin signaling and cell spreading alterations by rottlerin treatment of chick limb bud mesenchymal cells
    • Choi Y.A., Kim D.K., Kang S.S., Sonn J.K., Jin E.J. Integrin signaling and cell spreading alterations by rottlerin treatment of chick limb bud mesenchymal cells. Biochimie 2009, 91:624-631.
    • (2009) Biochimie , vol.91 , pp. 624-631
    • Choi, Y.A.1    Kim, D.K.2    Kang, S.S.3    Sonn, J.K.4    Jin, E.J.5
  • 14
    • 0029945149 scopus 로고    scopus 로고
    • Limbs: a model for pattern formation within the vertebrate body plan
    • Cohn M.J., Tickle C. Limbs: a model for pattern formation within the vertebrate body plan. Trends Genet. 1996, 12:253-257.
    • (1996) Trends Genet. , vol.12 , pp. 253-257
    • Cohn, M.J.1    Tickle, C.2
  • 15
    • 0344076113 scopus 로고    scopus 로고
    • Expression of N-cadherin, N-CAM, fibronectin and tenascin is stimulated by TGF-beta1, beta2, beta3 and beta5 during the formation of precartilage condensations
    • Chimal-Monroy J., Díaz de León L. Expression of N-cadherin, N-CAM, fibronectin and tenascin is stimulated by TGF-beta1, beta2, beta3 and beta5 during the formation of precartilage condensations. Int. J. Dev. Biol. 1999, 43:59-67.
    • (1999) Int. J. Dev. Biol. , vol.43 , pp. 59-67
    • Chimal-Monroy, J.1    Díaz de León, L.2
  • 17
    • 0033643593 scopus 로고    scopus 로고
    • Embryonic limb mesenchyme micromass culture as an in vitro model for chondrogenesis and cartilage maturation
    • DeLise A.M., Stringa E., Woodward W.A., Mello M.A., Tuan R.S. Embryonic limb mesenchyme micromass culture as an in vitro model for chondrogenesis and cartilage maturation. Methods Mol. Biol. 2000, 137:359-375.
    • (2000) Methods Mol. Biol. , vol.137 , pp. 359-375
    • DeLise, A.M.1    Stringa, E.2    Woodward, W.A.3    Mello, M.A.4    Tuan, R.S.5
  • 18
    • 33747620865 scopus 로고    scopus 로고
    • Glucocorticoids promote chondrogenic differentiation of adult human mesenchymal stem cells by enhancing expression of cartilage extracellular matrix genes
    • Derfoul A., Perkins G.L., Hall D.J., Tuan R.S. Glucocorticoids promote chondrogenic differentiation of adult human mesenchymal stem cells by enhancing expression of cartilage extracellular matrix genes. Stem Cells 2006, 24:1487-1495.
    • (2006) Stem Cells , vol.24 , pp. 1487-1495
    • Derfoul, A.1    Perkins, G.L.2    Hall, D.J.3    Tuan, R.S.4
  • 19
    • 0036788662 scopus 로고    scopus 로고
    • Analysis of N-cadherin function in limb mesenchymal chondrogenesis in vitro
    • DeLise A.M., Tuan R.S. Analysis of N-cadherin function in limb mesenchymal chondrogenesis in vitro. Dev. Dyn. 2002, 225:195-204.
    • (2002) Dev. Dyn. , vol.225 , pp. 195-204
    • DeLise, A.M.1    Tuan, R.S.2
  • 20
    • 0030678549 scopus 로고    scopus 로고
    • Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation
    • Ducy P., Zhang R., Geoffroy V., Ridall A.L., Karsenty G. Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation. Cell 1997, 89:747-754.
    • (1997) Cell , vol.89 , pp. 747-754
    • Ducy, P.1    Zhang, R.2    Geoffroy, V.3    Ridall, A.L.4    Karsenty, G.5
  • 22
    • 84885937068 scopus 로고    scopus 로고
    • Tissue engineering: chondrocytes and cartilage
    • Hardingham T., Tew S., Murdoch A. Tissue engineering: chondrocytes and cartilage. Arthritis Res. 2002, 4(Suppl. 3):S63-S68.
    • (2002) Arthritis Res. , vol.4 , Issue.SUPPL. 3
    • Hardingham, T.1    Tew, S.2    Murdoch, A.3
  • 24
    • 10444269518 scopus 로고    scopus 로고
    • Directing stem cell differentiation into the chondrogenic lineage in vitro
    • Heng B.C., Cao T., Lee E.H. Directing stem cell differentiation into the chondrogenic lineage in vitro. Stem Cells 2004, 22:1152-1167.
    • (2004) Stem Cells , vol.22 , pp. 1152-1167
    • Heng, B.C.1    Cao, T.2    Lee, E.H.3
  • 25
    • 0023666065 scopus 로고
    • Integrins: a family of cell surface receptors
    • Hynes R.O. Integrins: a family of cell surface receptors. Cell 1987, 48:549-554.
    • (1987) Cell , vol.48 , pp. 549-554
    • Hynes, R.O.1
  • 26
    • 0025218924 scopus 로고
    • VLA-proteins in the integrin family: structure, functions and their role on leucocytes
    • Hemler M.E. VLA-proteins in the integrin family: structure, functions and their role on leucocytes. Annu. Rev. Immunol. 1990, 8:365-400.
    • (1990) Annu. Rev. Immunol. , vol.8 , pp. 365-400
    • Hemler, M.E.1
  • 27
    • 69749128644 scopus 로고    scopus 로고
    • A comparison of autologous and allogenic bone marrow-derived mesenchymal stem cell transplantation in canine spinal cord injury
    • Jung D.I., Ha J., Kang B.T., Kim J.W., Quan F.S., Lee J.H., Woo E.J., Park H.M. A comparison of autologous and allogenic bone marrow-derived mesenchymal stem cell transplantation in canine spinal cord injury. J. Neurol. Sci. 2009, 285:67-77.
    • (2009) J. Neurol. Sci. , vol.285 , pp. 67-77
    • Jung, D.I.1    Ha, J.2    Kang, B.T.3    Kim, J.W.4    Quan, F.S.5    Lee, J.H.6    Woo, E.J.7    Park, H.M.8
  • 28
    • 58949104353 scopus 로고    scopus 로고
    • Advantage of mesenchymal stem cells (MSC) expansion directly from purified bone marrow CD105+ and CD271+ cells
    • Jarocha D., Lukasiewicz E., Majka M. Advantage of mesenchymal stem cells (MSC) expansion directly from purified bone marrow CD105+ and CD271+ cells. Folia Histochem. Cytobiol. 2008, 46:307-314.
    • (2008) Folia Histochem. Cytobiol. , vol.46 , pp. 307-314
    • Jarocha, D.1    Lukasiewicz, E.2    Majka, M.3
  • 29
  • 31
    • 57349172324 scopus 로고    scopus 로고
    • Isolation of human bone marrow mesenchymal stem cells using different membrane markers: comparison of colony/cloning efficiency, differentiation potential and molecular profile
    • Kastrinaki M.C., Andreakou I., Charbord P., Papadaki H.A. Isolation of human bone marrow mesenchymal stem cells using different membrane markers: comparison of colony/cloning efficiency, differentiation potential and molecular profile. Tissue Eng. Part C Methods 2008, 14:333-339.
    • (2008) Tissue Eng. Part C Methods , vol.14 , pp. 333-339
    • Kastrinaki, M.C.1    Andreakou, I.2    Charbord, P.3    Papadaki, H.A.4
  • 32
    • 55349109288 scopus 로고    scopus 로고
    • Hypoxic chondrogenic differentiation of human embryonic stem cells enhances cartilage protein synthesis and biomechanical functionality
    • Koay E.J., Athanasiou K.A. Hypoxic chondrogenic differentiation of human embryonic stem cells enhances cartilage protein synthesis and biomechanical functionality. Osteoarthritis Cartilage 2008, 16:1450-1456.
    • (2008) Osteoarthritis Cartilage , vol.16 , pp. 1450-1456
    • Koay, E.J.1    Athanasiou, K.A.2
  • 34
    • 0030899814 scopus 로고    scopus 로고
    • SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1(II) collagen gene
    • Lefebvre V., Huang W., Harley V.R., Goodfellow P.N., de Crombrugghe B. SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1(II) collagen gene. Mol. Cell. Biol. 1997, 4:2336-2346.
    • (1997) Mol. Cell. Biol. , vol.4 , pp. 2336-2346
    • Lefebvre, V.1    Huang, W.2    Harley, V.R.3    Goodfellow, P.N.4    de Crombrugghe, B.5
  • 36
    • 33845930820 scopus 로고    scopus 로고
    • The human OCT-4 isoforms differ in their ability to confer self-renewal
    • Lee J., Kim H.K., Rho J.Y., Han Y.M., Kim J. The human OCT-4 isoforms differ in their ability to confer self-renewal. J. Biol. Chem. 2006, 281:33554-33565.
    • (2006) J. Biol. Chem. , vol.281 , pp. 33554-33565
    • Lee, J.1    Kim, H.K.2    Rho, J.Y.3    Han, Y.M.4    Kim, J.5
  • 38
    • 0033838427 scopus 로고    scopus 로고
    • Isolation, characterization, and chondrogenic potential of human bone marrow-derived multipotential stromal cells
    • Majumdar M.K., Banks V., Peluso D.P., Morris E.A. Isolation, characterization, and chondrogenic potential of human bone marrow-derived multipotential stromal cells. J. Cell. Physiol. 2000, 185:98-106.
    • (2000) J. Cell. Physiol. , vol.185 , pp. 98-106
    • Majumdar, M.K.1    Banks, V.2    Peluso, D.P.3    Morris, E.A.4
  • 39
    • 0023603372 scopus 로고
    • Tenascin is associated with chondrogenic and osteogenic differentiation in vivo and promotes chondrogenesis in vitro
    • Mackie E.J., Thesleff I., Chiquet-Ehrismann R. Tenascin is associated with chondrogenic and osteogenic differentiation in vivo and promotes chondrogenesis in vitro. J. Cell. Biol. 1987, 105:2569-2579.
    • (1987) J. Cell. Biol. , vol.105 , pp. 2569-2579
    • Mackie, E.J.1    Thesleff, I.2    Chiquet-Ehrismann, R.3
  • 41
    • 0442276482 scopus 로고    scopus 로고
    • Matrix remodeling during endochondral ossification
    • Ortega N., Behonick D.J., Werb Z. Matrix remodeling during endochondral ossification. Trends Cell. Biol. 2004, 14:86-93.
    • (2004) Trends Cell. Biol. , vol.14 , pp. 86-93
    • Ortega, N.1    Behonick, D.J.2    Werb, Z.3
  • 42
    • 84934443078 scopus 로고    scopus 로고
    • Mesenchymal stem cells from adult bone marrow
    • Pittenger M.F. Mesenchymal stem cells from adult bone marrow. Methods Mol. Biol. 2008, 449:27-44.
    • (2008) Methods Mol. Biol. , vol.449 , pp. 27-44
    • Pittenger, M.F.1
  • 44
    • 33750321974 scopus 로고    scopus 로고
    • Premature induction of hypertrophy during in vitro chondrogenesis of human mesenchymal stem cells correlates with calcification and vascular invasion after ectopic transplantation in SCID mice
    • Pelttari K., Winter A., Steck E., Goetzke K., Hennig T., Ochs B.G., Aigner T., Richter W. Premature induction of hypertrophy during in vitro chondrogenesis of human mesenchymal stem cells correlates with calcification and vascular invasion after ectopic transplantation in SCID mice. Arthritis Rheum. 2006, 54:3254-3266.
    • (2006) Arthritis Rheum. , vol.54 , pp. 3254-3266
    • Pelttari, K.1    Winter, A.2    Steck, E.3    Goetzke, K.4    Hennig, T.5    Ochs, B.G.6    Aigner, T.7    Richter, W.8
  • 46
    • 0014841367 scopus 로고
    • The in vitro cultivation and differentiation capacities of myogenic cell lines
    • Richler C., Yaffe D. The in vitro cultivation and differentiation capacities of myogenic cell lines. Dev. Biol. 1970, 23:1-22.
    • (1970) Dev. Biol. , vol.23 , pp. 1-22
    • Richler, C.1    Yaffe, D.2
  • 47
    • 69949190806 scopus 로고    scopus 로고
    • Beta1 integrin deficiency results in multiple abnormalities of the knee joint
    • Raducanu A., Hunziker E.B., Drosse I., Aszódi A. Beta1 integrin deficiency results in multiple abnormalities of the knee joint. J. Biol. Chem. 2009, 284:23780-23792.
    • (2009) J. Biol. Chem. , vol.284 , pp. 23780-23792
    • Raducanu, A.1    Hunziker, E.B.2    Drosse, I.3    Aszódi, A.4
  • 50
    • 0037007146 scopus 로고    scopus 로고
    • In vitro cartilage formation by human adult stem cells from bone marrow stroma defines the sequence of cellular and molecular events during chondrogenesis
    • Sekiya I., Vuoristo J.T., Larson B.L., Prockop D.J. In vitro cartilage formation by human adult stem cells from bone marrow stroma defines the sequence of cellular and molecular events during chondrogenesis. Proc. Natl. Acad. Sci. USA 2002, 99:4397-4402.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 4397-4402
    • Sekiya, I.1    Vuoristo, J.T.2    Larson, B.L.3    Prockop, D.J.4
  • 52
    • 0031868887 scopus 로고    scopus 로고
    • Inhibition of chondrogenesis by integrin antibody in vitro
    • Shakibaei M. Inhibition of chondrogenesis by integrin antibody in vitro. Exp. Cell. Res. 1998, 240:95-106.
    • (1998) Exp. Cell. Res. , vol.240 , pp. 95-106
    • Shakibaei, M.1
  • 53
    • 4544245138 scopus 로고    scopus 로고
    • Isolation of BM mesenchymal stem cells by plastic adhesion or negative selection: phenotype, proliferation kinetics and differentiation potential
    • Tondreau T., Lagneaux L., Dejeneffe M., Delforge A., Massy M., Mortier C., Bron D. Isolation of BM mesenchymal stem cells by plastic adhesion or negative selection: phenotype, proliferation kinetics and differentiation potential. Cytotherapy 2004, 6:372-379.
    • (2004) Cytotherapy , vol.6 , pp. 372-379
    • Tondreau, T.1    Lagneaux, L.2    Dejeneffe, M.3    Delforge, A.4    Massy, M.5    Mortier, C.6    Bron, D.7
  • 54
    • 0142103359 scopus 로고    scopus 로고
    • Transforming growth factor-beta-mediated chondrogenesis of human mesenchymal progenitor cells involves N-cadherin and mitogenactivated protein kinase and Wnt signaling cross-talk
    • Tuli R., Tuli S., Nandi S., Huang X., Manner P.A., Hozack W.J., Danielson K.G., Hall D.J., Tuan R.S. Transforming growth factor-beta-mediated chondrogenesis of human mesenchymal progenitor cells involves N-cadherin and mitogenactivated protein kinase and Wnt signaling cross-talk. J. Biol. Chem. 2003, 278:41227-41236.
    • (2003) J. Biol. Chem. , vol.278 , pp. 41227-41236
    • Tuli, R.1    Tuli, S.2    Nandi, S.3    Huang, X.4    Manner, P.A.5    Hozack, W.J.6    Danielson, K.G.7    Hall, D.J.8    Tuan, R.S.9
  • 55
    • 34548489858 scopus 로고    scopus 로고
    • Regulation of chondrocyte differentiation by the actin cytoskeleton and adhesive interactions
    • Woods A., Wang G., Beier F. Regulation of chondrocyte differentiation by the actin cytoskeleton and adhesive interactions. J. Cell. Physiol. 2007, 213:1-8.
    • (2007) J. Cell. Physiol. , vol.213 , pp. 1-8
    • Woods, A.1    Wang, G.2    Beier, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.