Small molecule ion channel match making: A natural fit for new ASIC ligands

Neuron

Volumn 68, Issue 1, 2010, Pages 1-3

  Bagriantsev, Sviatoslav N ^a   Minor, Daniel L ^a,b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 GUANIDINE 4 METHYLQUINAZOLINE; 5 MERCAPTO 2 NITROBENZOIC ACID; ACID SENSING ION CHANNEL; EPITHELIAL SODIUM CHANNEL; NITROBENZOIC ACID DERIVATIVE; PROTEIN APETX2; PROTEIN INHIBITOR; PSALMOTOXIN 1; UNCLASSIFIED DRUG;

ACIDIFICATION; ACIDOSIS; BINDING AFFINITY; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; DESENSITIZATION; ELECTROPHYSIOLOGY; ENZYME ACTIVATION; EXTRACELLULAR FLUID; HYPERALGESIA; INFLAMMATION; PAIN; PH; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; SHORT SURVEY; STRUCTURE ACTIVITY RELATION;

EID: 77957310023     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuron.2010.09.038     Document Type: Short Survey

References (15)

1. Cushman K.A., Marsh-Haffner J., Adelman J.P., McCleskey E.W. J. Gen. Physiol. 2007, 129:345-350.
2. Deval E., Noël J., Lay N., Alloui A., Diochot S., Friend V., Jodar M., Lazdunski M., Lingueglia E. EMBO J. 2008, 27:3047-3055.
3. Deval E., Gasull X., Noel J., Salinas M., Baron A., Diochot S., Lingueglia E. Pharmacol. Ther. 2010, in press. Published online August 31, 2010. 10.1016/j.pharmthera.2010.08.006.
4. Diochot S., Salinas M., Baron A., Escoubas P., Lazdunski M. Toxicon 2007, 49:271-284.
5. Dunlop J., Bowlby M., Peri R., Vasilyev D., Arias R. Nat. Rev. Drug Discov. 2008, 7:358-368.
6. Erlanson D.A., Wells J.A., Braisted A.C. Annu. Rev. Biophys. Biomol. Struct. 2004, 33:199-223.
7. Gonzales E.B., Kawate T., Gouaux E. Nature 2009, 460:599-604.
8. Jasti J., Furukawa H., Gonzales E.B., Gouaux E. Nature 2007, 449:316-323.
9. Krishtal O. Trends Neurosci. 2003, 26:477-483.
10. Mazzuca M., Heurteaux C., Alloui A., Diochot S., Baron A., Voilley N., Blondeau N., Escoubas P., Gélot A., Cupo A., et al. Nat. Neurosci. 2007, 10:943-945.
11. Regunathan S. AAPS J. 2006, 8:E479-E484.
12. Sluka K.A., Winter O.C., Wemmie J.A. Curr. Opin. Drug Discov. Dev. 2009, 12:693-704.
13. Wemmie J.A., Price M.P., Welsh M.J. Trends Neurosci. 2006, 29:578-586.
14. Xiong Z.G., Pignataro G., Li M., Chang S.Y., Simon R.P. Curr. Opin. Pharmacol. 2008, 8:25-32.
15. Yu Y., Chen Z., Li W.-G., Cao H., Feng E.-G., Yu F., Liu H., Jiang H., Xu T.-L. Neuron 2010, 68:61-72. this issue.