A review of synergy concepts of nonlinear blending and dose-reduction profiles

Frontiers in Bioscience - Scholar

Volumn 2 S, Issue 2, 2010, Pages 483-503

  Peterson, John J ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

Antagonism; Berenbaum interaction index; Bliss independence; Coalism; Combination index; Confidence region; Dose reduction index; Dose reduction profile; Dosewise additivity; Excess over highest single agent; Isobole; Isobologram; Loewe synergy; Min test; Minto white model; Nonlinear blending; Partial inhibitor; Potentiation; Response surface; Review; Synergy

Indexed keywords

FOLIC ACID; GLUTAMIC ACID DERIVATIVE; N [[5 [2 (2 AMINO 4,6,7,8 TETRAHYDRO 4 OXO 1H PYRIMIDO[5,4 B][1,4]THIAZIN 6 YL)ETHYL] 2 THIENYL]CARBONYL]GLUTAMIC ACID; PYRIMIDINE DERIVATIVE; TRIMETREXATE;

DOSE RESPONSE; DRUG COMBINATION; DRUG POTENTIATION; REVIEW; THEORETICAL MODEL;

DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; DRUG SYNERGISM; FOLIC ACID; GLUTAMATES; MODELS, THEORETICAL; PYRIMIDINES; TRIMETREXATE;

EID: 77957305891     PISSN: 19450516     EISSN: 19450524     Source Type: Journal    
DOI: 10.2741/s80     Document Type: Review

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