A large, systematic molecular-genetic study of G6PD in Indian populations identifies a new non-synonymous variant and supports recent positive selection

Infection, Genetics and Evolution

Volumn 10, Issue 8, 2010, Pages 1228-1236

  Sarkar, Somosree ^a   Biswas, Nidhan K ^a   Dey, Badal ^a   Mukhopadhyay, Debashis ^b   Majumder, Partha P ^a,c  

^a INDIAN STATISTICAL INSTITUTE   (India)

^b SAHA INSTITUTE OF NUCLEAR PHYSICS   (India)

^c NATIONAL INSTITUTE OF BIOMEDICAL GENOMICS   (India)

Author keywords

Extended haplotype homozygosity; G6PD deficiency; Geographical sub structure; Homology modeling; Natural selection; Non synonymous variant

Indexed keywords

GLUCOSE 6 PHOSPHATE DEHYDROGENASE;

ARTICLE; CONTROLLED STUDY; EXON; FEMALE; GENE FREQUENCY; GENE MUTATION; GENE SEQUENCE; GENETIC VARIABILITY; GENOTYPE; GEOGRAPHIC DISTRIBUTION; GLUCOSE 6 PHOSPHATE DEHYDROGENASE DEFICIENCY; HAPLOTYPE; HOMOZYGOSITY; HUMAN; INDIA; INTRON; MALARIA; MALE; MOLECULAR GENETICS; POPULATION RESEARCH; PRIORITY JOURNAL;

BASE SEQUENCE; CHROMOSOMES, HUMAN, X; ETHNIC GROUPS; FEMALE; GENE FREQUENCY; GENES, X-LINKED; GENETIC VARIATION; GENOTYPE; GLUCOSEPHOSPHATE DEHYDROGENASE; GLUCOSEPHOSPHATE DEHYDROGENASE DEFICIENCY; HAPLOTYPES; HUMANS; IMMUNITY, INNATE; INDIA; MALARIA; MALE; POLYMORPHISM, GENETIC; SELECTION, GENETIC;

EID: 77957295151     PISSN: 15671348     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.meegid.2010.08.003     Document Type: Article

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