Identifying the ion channels responsible for signaling gastro-intestinal based pain

Pharmaceuticals

Volumn 3, Issue 9, 2010, Pages 2768-2798

  Brierley, Stuart M ^a,b   Hughes, Patrick A ^a,b   Harrington, Andrea M ^a,b   Rychkov, Grigori Y ^b   Blackshaw, L Ashley ^a,b  

^a ROYAL ADELAIDE HOSPITAL   (Australia)

^b UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

ASICs; TRPA1; TRPV1; TRPV4; Visceral pain

Indexed keywords

ACID SENSING ION CHANNEL; ALLYL ISOTHIOCYANATE; ANTISENSE OLIGODEOXYNUCLEOTIDE; ION CHANNEL; PROTEINASE ACTIVATED RECEPTOR 2; SODIUM CHANNEL NAV1.8; SODIUM CHANNEL NAV1.9; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1; TRANSIENT RECEPTOR POTENTIAL CHANNEL AFFECTING AGENT; TUMOR NECROSIS FACTOR ALPHA; VANILLOID RECEPTOR 1; VANILLOID RECEPTOR 1 ANTAGONIST; VANILLOID RECEPTOR 4; VOLTAGE GATED POTASSIUM CHANNEL; VOLTAGE GATED SODIUM CHANNEL;

CLINICAL TRIAL; COLITIS; DISEASE SEVERITY; DRUG EFFICACY; DRUG MECHANISM; FUNCTIONAL DISEASE; GASTROINTESTINAL PAIN; GASTROINTESTINAL SYMPTOM; GENE EXPRESSION; HUMAN; HYPERALGESIA; HYPERSENSITIVITY; INTESTINE INNERVATION; NERVE CONDUCTION; NEUROGENIC INFLAMMATION; NOCICEPTIVE RECEPTOR; NONHUMAN; PAIN THRESHOLD; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; REVIEW; SENSORY NERVE; SIGNAL TRANSDUCTION; STIMULUS RESPONSE; ULCERATIVE COLITIS; VAGUS NERVE STIMULATION; VISCERAL PAIN;

EID: 77957262934     PISSN: None     EISSN: 14248247     Source Type: Journal    
DOI: 10.3390/ph3092768     Document Type: Review

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