Loss of lysophosphatidylcholine acyltransferase 1 leads to photoreceptor degeneration in rd11 mice

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 35, 2010, Pages 15523-15528

  Friedman, James S ^a   Chang, Bo ^b   Krauth, Daniel S ^a   Lopez, Irma ^c   Waseem, Naushin H ^d   Hurd, Ron E ^b   Feathers, Kecia L ^e   Branham, Kari E ^e   Shaw, Manessa ^e   Thomas, George E ^e   Brooks, Matthew J ^a   Liu, Chunqiao ^a   Bakeri, Hirva A ^a   Campos, Maria M ^a   Maubaret, Cecilia ^d   Webster, Andrew R ^d   Rodriguez, Ignacio R ^a   Thompson, Debra A ^e   Bhattacharya, Shomi S ^d   Koenekoop, Robert K ^c   Heckenlively, John R ^e   Swaroop, Anand ^a,e   more..

^a NATIONAL EYE INSTITUTE   (United States)

^b JACKSON LABORATORY   (United States)

^c MONTREAL CHILDREN S HOSPITAL   (Canada)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

^e UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Gene discovery; Lipid enzyme; Phospholipid remodeling; Retinal degeneration; Visual dysfunction

Indexed keywords

1 ACYLGLYCEROPHOSPHOCHOLINE ACYLTRANSFERASE;

ANIMAL EXPERIMENT; ARTICLE; CHROMOSOME 13; CONTROLLED STUDY; DEGENERATION; ENZYME BLOOD LEVEL; FOLLOW UP; GENE MUTATION; GENETIC SCREENING; HOMEOSTASIS; LINKAGE ANALYSIS; LIPID ANALYSIS; MOUSE; NONHUMAN; PHOSPHOLIPID SYNTHESIS; PHOTORECEPTOR; PRIORITY JOURNAL; RETINITIS PIGMENTOSA;

1-ACYLGLYCEROPHOSPHOCHOLINE O-ACYLTRANSFERASE; ANIMALS; BASE SEQUENCE; BLOTTING, NORTHERN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMOSOME MAPPING; DNA MUTATIONAL ANALYSIS; HUMANS; IMMUNOBLOTTING; LEBER CONGENITAL AMAUROSIS; LIPIDS; MICE; MICE, INBRED BALB C; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, INBRED STRAINS; MICE, MUTANT STRAINS; MICROSCOPY, ELECTRON, TRANSMISSION; PHOSPHATIDYLCHOLINES; PHOTORECEPTOR CELLS, VERTEBRATE; RETINAL DEGENERATION; RETINITIS PIGMENTOSA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

MUS;

EID: 77957259233     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1002897107     Document Type: Article

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