Coccidioidal meningitis: Clinical presentation and management in the fluconazole era

Medicine

Volumn 89, Issue 5, 2010, Pages 251-284

  Mathisen, Glenn ^a,b,c,d   Shelub, Aaron ^a,b   Truong, Jonathan ^a,b,c,d,f   Wigen, Christine ^a,b,c,d,e  

^a Multicampus Infectious Disease Program   (United States)

^b CEDARS SINAI MEDICAL CENTER   (United States)

^c OLIVE VIEW UCLA MEDICAL CENTER   (United States)

^d West Los Angeles Medical Center   (United States)

^e Los Angeles County Department of Public Health   (United States)

^f KAISER PERMANENTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABACAVIR; AMPHOTERICIN B; AMPHOTERICIN B DEOXYCHOLATE; AMPHOTERICIN B LIPID COMPLEX; DARUNAVIR; EMTRICITABINE; FLUCONAZOLE; ITRACONAZOLE; KETOCONAZOLE; LAMIVUDINE; LOPINAVIR PLUS RITONAVIR; MICONAZOLE; NELFINAVIR; POSACONAZOLE; RITONAVIR; TENOFOVIR; VORICONAZOLE; ZIDOVUDINE; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADRENAL INSUFFICIENCY; ADULT; AGED; ARACHNOIDITIS; ARTICLE; CEREBROSPINAL FLUID ANALYSIS; CLINICAL FEATURE; COCCIDIOIDES IMMITIS; COCCIDIOIDOMYCOSIS; COMORBIDITY; DRUG MEGADOSE; DRUG SUBSTITUTION; DRUG WITHDRAWAL; EOSINOPHILIA; EVENING DOSAGE; FEMALE; GASTROINTESTINAL SYMPTOM; HEADACHE; HEART VENTRICLE TACHYCARDIA; HEMATOCRIT; HIGH RISK POPULATION; HISPANIC; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HYDROCEPHALUS; HYPOKALEMIA; HYPOMAGNESEMIA; IMMUNOCOMPROMISED PATIENT; LEUKOCYTOSIS; LIVER TOXICITY; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; MENINGEAL BIOPSY; MONOTHERAPY; MORNING DOSAGE; NAUSEA; NEPHROTOXICITY; NEUROLOGICAL COMPLICATION; NEURORADIOLOGY; NEUROSURGERY; PHOTOSENSITIVITY; PRIORITY JOURNAL; RISK FACTOR; SEROLOGY; SIDE EFFECT; STROKE; THORAX RADIOGRAPHY; TORSADE DES POINTES; VISUAL DISORDER; VOMITING; ACQUIRED IMMUNODEFICIENCY SYNDROME; AIDS-RELATED OPPORTUNISTIC INFECTIONS; CASE REPORT; CEREBROSPINAL FLUID; COCCIDIOIDES; COMPLICATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ISOLATION AND PURIFICATION; MENINGITIS; MICROBIOLOGY; MIDDLE AGED; YOUNG ADULT;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ADULT; AGED; AIDS-RELATED OPPORTUNISTIC INFECTIONS; AMPHOTERICIN B; ANTI-BACTERIAL AGENTS; ANTIFUNGAL AGENTS; COCCIDIOIDES; COCCIDIOIDOMYCOSIS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLUCONAZOLE; HUMANS; HYDROCEPHALUS; MALE; MENINGITIS; MIDDLE AGED; RADIOGRAPHY, THORACIC; YOUNG ADULT;

EID: 77957257351     PISSN: 00257974     EISSN: None     Source Type: Journal    
DOI: 10.1097/MD.0b013e3181f378a8     Document Type: Article

References (71)

1. Abbott KH, Cutler OI. Chronic coccidioidal meningitis: review of the literature and report of seven cases. Arch Pathol. 1936;21:320-330.
2. Ampel NM. Delayed-type hypersensitivity, in vitro T-cell responsiveness and risk of active coccidioidomycosis among HIV-infected patients living in the coccidioidal endemic area. Med Mycol. 1999;37:245-250.
3. Anstead GM, Corcoran G, Lewis J, Berg D, Graybill JR. Refractory coccidioidomycosis treated with posaconazole. Clin Infect Dis. 2005;40:1770-1776. EEpub 2005 May 13.
4. Arsura EL, Johnson R, Penrose J, Stewart K, Kilgore W, Reddy CM, Bobba RK. Neuroimaging as a guide to predict outcomes for patients with coccidioidal meningitis. Clin Infect Dis. 2005;40:624-627.
5. Berry CD, Stevens DA, Hassid EI, Pappagianis D, Happs EL, Sahrakar K. A new method for the treatment of chronic fungal meningitis: continuous infusion into the cerebrospinal fluid for coccidioidal meningitis. Am J Med Sci. 2009;338:79-82.
6. Blair JE, Coakley B, Santelli AC, Hentz JG, Wengenack NL. Serologic testing for symptomatic coccidioidomycosis in immunocompetent and immunosuppressed hosts. Mycopathologia. 2006;162:317-324.
7. Blair JE. Coccidioidomycosis in liver transplantation. Liver Transpl. 2006;12:31-39.
8. Bouza E, Dreyer JS, Hewitt WL, Meyer RD. Coccidioidal meningitis. An analysis of thirty-one cases and review of the literature. Medicine (Baltimore). 1981;60:139-172.
9. Brockmeyer NH, Tillmann I, Mertins L, Barthel B, Goos M. Pharmacokinetic interaction of fluconazole and zidovudine in HIV-positive patients. Eur J Med Res. 1997;2:377-383.
10. Caldwell JW, Arsura EL, Kilgore WB, Garcia AL, Reddy V, Johnson RH. Coccidioidomycosis in pregnancy during an epidemic in California. Obstet Gynecol. 2000;95:236-239.
11. Capilla J, Clemons KV, Sobel RA, Stevens DA. Efficacy of amphotericin B lipid complex in a rabbit model of coccidioidal meningitis. J Antimicrob Chemother. 2007;60:673-676. EEpub 2007 Jul 23.
12. Carbonara S, Regazzi M, Ciraci E, Villani P, Stano F, Cusato M, Heichen M, Monno L. Long-term efficacy and safety of TDM-assisted combination of voriconazole plus efavirenz in an AIDS patient with cryptococcosis and liver cirrhosis. Ann Pharmacother. 2009;43: 978-984. EEpub 2009 Apr 21.
13. Carmichael JK. Coccidioidomycosis in HIV-infected persons. Clin Infect Dis. 2006;42:1059.
14. Classen DC, Burke JP, Smith CB. Treatment of coccidioidal meningitis with fluconazole. J Infect Dis. 1988;158:903-904.
15. Clemons KV, Sobel RA, Williams PL, Pappagianis D, Stevens DA. Efficacy of intravenous liposomal amphotericin B (AmBisome) against coccidioidal meningitis in rabbits. Antimicrob Agents Chemother. 2002;46:2420-2426.
16. Cloud G, Dismukes WE. Ketoconazole treatment of coccidioidal meningitis. Ann N Y Acad Sci. 1988;544:488-496.
17. Cortez KJ, Walsh TJ, Bennett JE. Successful treatment of coccidioidal meningitis with voriconazole. Clin Infect Dis. 2003;36:1619-1622.
18. Courville CB, Abbott KH. Pathology of coccidioidal granuloma of the central nervous system and its envelopes. Bull Los Angeles Neurol Soc. 1938;3:27-e41.
19. Crum NF, Ballon-Landa G. Coccidioidomycosis in pregnancy: case report and review of the literature. Am J Med. 2006;119:993.e11-e17.
20. Derensinski S, Hector R. The History of Coccidioidomycosis I. The Early History of the Disease in North America. II. Biographies of Four Coccidioidomycologists. In: Proceedings of the 5th International Conference of Coccidioidomycosis; Stanford University, 24-27 August, 1994. Washington, DC: National Foundation for Infectious Diseases; 1996.
21. Dewsnup DH, Galgiani JN, Graybill JR, Diaz M, Rendon A, Cloud GA, Stevens DA. Is it ever safe to stop azole therapy for Coccidioides immitis meningitis? Ann Intern Med. 1996;124:305-310.
22. Einstein HE, Holeman CW, Sandidge LL, Holden DH. Coccidioidal meningitis. The use of amphotericin B in treatment. Calif Med. 1961;94:339-343.
23. Fish DG, Ampel NM, Galgiani JN, Dols CL, Kelly PC, Johnson CH, Pappagianis D, Edwards JE, Wasserman RB, Clark RJ, Antoniskis D, Larsen RA, Englender SJ, Petersen EA. Coccidioidomycosis during human immunodeficiency virus infection. A review of 77 patients. Medicine (Baltimore). 1990;69:384-391. (Pubitemid 20386534)
24. Galgiani JN, Ampel NM, Blair J, Catanzaro A, Johnson RH, Stevens DA, Williams PL. Coccidioidomycosis IDSA guidelines. Clin Infect Dis. 2005;41:1217-1223. EEpub 2005 Sep 20.
25. Galgiani JN, Catanzaro A, Cloud GA, Levine BE, Williams PL, Johnson RH, Rendon A, Mirels LF, Lutz JE, Holloway M, Galgiani JN. Fluconazole therapy for coccidioidal meningitis. The NIAID-Mycoses Study Group. Ann Intern Med. 1993;119:28-35.
26. Garbino J, Lew DP, Romand JA, Hugonnet S, Auckenthaler R, Pittet D. Prevention of severe Candida infections in nonneutropenic, high-risk, critically ill patients: a randomized, double-blind, placebo-controlled trial in patients treated by selective digestive decontamination. Intensive Care Med. 2002;28:1708-1717. EEpub 2002 Nov 1.
27. Graybill JR, Sun SH, Ahrens J. Treatment of murine coccidioidal meningitis with fluconazole (UK 49,858). J Med Vet Mycol. 1986;24:113-119. (Pubitemid 17190713)
28. Hooper JE, Lu Q, Pepkowitz SH. Disseminated coccidioidomycosis in pregnancy. Arch Pathol Lab Med. 2007;131:652-655.
29. Johnson LB, Kauffman CA. Voriconazole: a new triazole antifungal agent. Clin Infect Dis. 2003;36:630-637.
30. Johnson RH, Einstein HE. Coccidioidal meningitis. Clin Infect Dis. 2006;42:103-107.
31. Kaplan JE, Benson C, Holmes KH, Brooks JT, Pau A, Masur H; Centers for Disease Control and Prevention (CDC); National Institutes of Health; HIV Medicine Association of the Infectious Diseases Society of America. Guidelines for prevention and treatment of opportunistic infections in HIV-infected adults and adolescents: recommendations from CDC, the National Institutes of Health, and the HIV Medicine Association of the Infectious Diseases Society of America. MMWR Recomm Rep. 2009;58(RR-4):1-207.
32. Kelly PC. Coccidioidal meningitis. In: Stevens DA, ed. Coccidioidomycosis. A Text. New York: Plenum Medical Book Company; 1980:163-193.
33. Kriesel JD, Sutton DA, Schulman S, Fothergill AW, Rinaldi MG. Persistent pulmonary infection with an azole-resistant Coccidioides species. Med Mycol. 2008;46:607-610.
34. Li RK, Ciblak MA, Nordoff N, Pasarell L, Warnock DW, McGinnis MR. In vitro activities of voriconazole, itraconazole, and amphotericin B against Blastomyces dermatitidis, Coccidioides immitis, and Histoplasma capsulatum. Antimicrob Agents Chemother. 2000;44:1734-1736.
35. Liu P, Foster G, Gandelman K, LaBadie RR, Allison MJ, Gutierrez MJ, Sharma A. Steady-state pharmacokinetic and safety profiles of voriconazole and ritonavir in healthy male subjects. Antimicrob Agents Chemother. 2007;51:3617-3626. EEpub 2007 Jul 23.
36. Malani AN, Aronoff DM. Voriconazole-induced photosensitivity. Clin Med Res. 2008;6:83-85. EEpub 2008 Sep 18.
37. Masannat FY, Ampel NM. Coccidioidomycosis in patients with HIV-1 infection in the era of potent antiretroviral therapy. Clin Infect Dis. 2010;50:1-7.
38. McMahon JH, Grayson ML. Torsades de pointes in a patient receiving fluconazole for cerebral cryptococcosis. Am J Health Syst Pharm. 2008;65:619-623.
39. Mischel PS, Vinters HV. Coccidioidomycosis of the central nervous system: neuropathological and vasculopathic manifestations and clinical correlates. Clin Infect Dis. 1995;20:400-405.
40. Morris M. Coccidioides of the central nervous system. Cal West Med. 1924;22:483-485.
41. Nierenberg NE, Thompson GR, Lewis JS, Hogan BK, Patterson TF. Voriconazole use and pharmacokinetics in combination with interferon-gamma for refractory cryptococcal meningitis in a patient receiving low-dose ritonavir. Med Mycol. 2010;48:532-536. EEpub 2009 Oct 19.
42. Norgaard M, Pedersen L, Gislum M, Erichsen R, SLgaard KK, SchLnheyder HC, SLrensen HT. Maternal use of fluconazole and risk of congential malformations: a Danish population-based cohort study. J Antimicrob Chemother. 2008;62:172-176
43. Ophuls W. Coccidioidal granulomas. J Am Med Assoc. 1905;14:1291.
44. Pascual A, Calandra T, Bolay S, Buclin T, Bille J, Marchetti O. Voriconazole therapeutic drug monitoring in patients with invasive mycoses improves efficacy and safety outcomes. Clin Infect Dis. 2008;46:201-211.
45. Peterson CM, Johnson SL, Kelly JV, Kelly PC. Coccidioidal meningitis and pregnancy: a case report. Obstet Gynecol. 1989;73:835-836.
46. Pitisuttithum P, Negroni R, Graybill JR, Bustamante B, Pappas P, Chapman S, Hare RS, Hardalo CJ. Activity of posaconazole in the treatment of central nervous system fungal infections. J Antimicrob Chemother. 2005;56:745-755. EEpub 2005 Aug 31.
47. Posadas A. Un nuevo caso de micosis fungoide con psorospermias. Circulo Medico Argentino. 1892;5:585-597.
48. Prabhu RM, Bonnell M, Currier BL, Orenstein R. Successful treatment of disseminated nonmeningeal coccidioidomycosis with voriconazole. Clin Infect Dis. 2004;39:e74-e77.
49. Proia LA, Tenorio AR. Successful use of voriconazole for treatment of Coccidioides meningitis. Antimicrob Agents Chemother. 2004;48:2341.
50. Pursley TJ, Blomquist IK, Abraham J, Andersen HF, Bartley JA. Fluconazole-induced congenital anomalies in three infants. Clin Infect Dis. 1996;22:336-340.
51. Rex J, Pappas PG, Karchmer AW, Sobel J, Edwards JE, Hadley S, Brass C, Vazquez JA, Chapman SW, Horowitz HW, Zervos M, McKinsey D, Lee J, Babinchak T, Bradsher RW, Cleary JD, Cohen DM, Danziger L, Goldman M, Goodman J, Hilton E, Hyslop NE, Kett DH, Lutz J, Rubin RH, Scheld WM, Schuster M, Simmons B, Stein DK, Washburn RG, Mautner L, Chu TC, Panzer H, Rosenstein RB, Booth J; National Institute of Allergy and Infectious Diseases Mycoses Study Group. A randomized and blinded multicenter trial of high-dose fluconazole plus placebo versus fluconazole plus amphotericin B as therapy for candidemia and its consequences in nonneutropenic subjects. Clin Infect Dis. 2003;36:1221-1228. EEpub 2003 May 8.
52. Rixford E, Gilchrist TC. Two cases of protozoan (coccidioidal) infection of the skin and other organs. Johns Hopkins Hosp Rep. 1896;1:209-269.
53. Romeo JH, Rice LB, McQuarrie IG. Hydrocephalus in coccidioidal meningitis: case report and review of the literature. Neurosurgery. 2000;47:773-777.
54. Santhana Krishnan SG, Cobbs RK. Reversible acute adrenal insufficiency caused by fluconazole in a critically ill patient. Postgrad Med J. 2006;82:e23.
55. Shirvani VN, Gaucher DJ, Johnson RH, et al. Coccidioidal Meningitis: Evaluation of Intrathecal Amphotericin B after Non-Response to Fluconazole. 45th Coccidioidomycosis Study Group. Tucson, Arizona. March 31, 2001.
56. Singh VR, Smith DK, Lawrence J, Kelly PC, Thomas AR, Spitz B, Sarosi GA. Coccidioidomycosis in patients infected with human immunodeficiency virus: review of 91 cases at a single institution. Clin Infect Dis. 1996;23:563-568.
57. Sorensen KN, Sobel RA, Clemons KV, Pappagianis D, Stevens DA, Williams PL. Comparison of fluconazole and itraconazole in a rabbit model of coccidioidal meningitis. Antimicrob Agents Chemother. 2000;44:1512-1517.
58. Spinello IM, Johnson RH, Baqi S. Coccidioidomycosis and pregnancyVa review. Ann N Y Acad Sci. 2007;1111:358-364.
59. Stevens DA, Rendon A, Gaona-Flores V, Catanzaro A, Anstead GM, Pedicone L, Graybill JR. Posaconazole therapy for chronic refractory coccidioidomycosis. Chest. 2007;132:952-958. EEpub 2007 Jun 15.
60. Stevens DA, Shatsky SA. Intrathecal amphotericin in the management of coccidioidal meningitis. Semin Respir Infect. 2001;16:263-269.
61. Sung JP, Grendahl JG, Levine HB. Intravenous and intrathecal miconazole therapy for systemic mycoses. West J Med. 1977;126:5-13.
62. Tholakanahalli VN, Potti A, Hanley JF, Merliss AD. Fluconazole-induced torsade de pointes. Ann Pharmacother. 2001;35:432-434.
63. Tucker RM, Denning DW, Dupont B, Stevens DA. Itraconazole therapy for chronic coccidioidal meningitis. Ann Intern Med. 1990;112:108-112.
64. Tucker RM, Galgiani JN, Denning DW, Hanson LH, Graybill JR, Sharkey K, Eckman MR, Salemi C, Libke R, Klein RA, et al. Treatment of coccidioidal meningitis with fluconazole. Rev Infect Dis. 1990;12(Suppl 3):S380-S389.
65. Vincent T, Galgiani JN, Huppert M, Salkin D. The natural history of coccidioidal meningitis: VA-Armed Forces cooperative studies, 1955-1958. Clin Infect Dis. 1993;16:247-254.
66. Williams PL, Johnson R, Pappagianis D, Einstein H, Slager U, Koster FT, Eron JJ, Morrison J, Aguet J, River ME. Vasculitic and encephalitic complications associated with Coccidioides immitis infection of the central nervous system in humans: report of 10 cases and review. Clin Infect Dis. 1992;14:673-682.
67. Williams PL. Coccidioidal meningitis. Ann N Y Acad Sci. 2007;1111:377-384. EEpub 2007 Mar 15.
68. Williams PL. Vasculitic complications associated with coccidioidal meningitis. Sem Resp Infect. 2001;16:270-279.
69. Winn WA. The use of amphotericin B in the treatment of coccidioidal disease. Am J Med. 1959;27:617.
70. Winston DJ, Kurtz TO, Fleischmann J, Morgan D, Batzdorf U, Stern WE. Successful treatment of spinal arachnoiditis due to coccidioidomycosis. Case report. J Neurosurg. 1983;59:328-331.
71. Yakiwchuk EM, Foisy MM, Hughes CA. Complexity of interactions between voriconazole and antiretroviral agents. Ann Pharmacother. 2008;42:698-703