The cleavage of N-cadherin is essential for chondrocyte differentiation

Biochemical and Biophysical Research Communications

Volumn 400, Issue 4, 2010, Pages 493-499

  Nakazora, Shigeto ^a   Matsumine, Akihiko ^a   Iino, Takahiro ^a   Hasegawa, Masahiro ^a   Kinoshita, Ayae ^b   Uemura, Kengo ^b   Niimi, Rui ^a   Uchida, Atsumasa ^a   Sudo, Akihiro ^a  

^a MIE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

N cadherin

Indexed keywords

ADAM10 ENDOPEPTIDASE; AGGRECAN; CELL MARKER; COLLAGEN TYPE 10; COLLAGEN TYPE 2; INSULIN; MUTANT PROTEIN; NERVE CELL ADHESION MOLECULE; PROTEOGLYCAN;

ANIMAL CELL; ARTICLE; CARTILAGE CELL; CELL AGGREGATION; CELL CLONING; CELL DIFFERENTIATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EMBRYO; GENE OVEREXPRESSION; MARKER GENE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN METABOLISM; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WILD TYPE;

ADAM PROTEINS; AMINO ACID SEQUENCE; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ANTIGENS, CD; CADHERINS; CARTILAGE; CELL DIFFERENTIATION; CELL LINE, TUMOR; CHONDROCYTES; CHONDROGENESIS; HUMANS; MEMBRANE PROTEINS; MICE; MOLECULAR SEQUENCE DATA; MUTATION; PROTEOGLYCANS;

EID: 77957252954     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.08.070     Document Type: Article

References (28)

1. Provot S., Schipani E. Molecular mechanisms of endochondral bone development. Biochem. Biophys. Res. Commun. 2005, 328:658-665.
2. Goldring M.B., Tsuchimochi K., Ijiri K. The control of chondrogenesis. J. Cell Biochem. 2006, 97:33-44.
3. Tuan R.S. Cellular signaling in developmental chondrogenesis: N-cadherin, Wnts, and BMP-2. J Bone Joint Surg. Am. 2003, 85-A(Suppl. 2):137-141.
4. Tuan R.S. Biology of developmental and regenerative skeletogenesis. Clin. Orthop. Relat. Res. 2004, S105-S117.
5. Woods A., Wang G., Beier F. Regulation of chondrocyte differentiation by the actin cytoskeleton and adhesive interactions. J Cell Physiol. 2007, 213:1-8.
6. DeLise A.M., Tuan R.S. Alterations in the spatiotemporal expression pattern and function of N-cadherin inhibit cellular condensation and chondrogenesis of limb mesenchymal cells in vitro. J. Cell Biochem. 2002, 87:342-359.
7. Pokutta S., Herrenknecht K., Kemler R., Engel J. Conformational changes of the recombinant extracellular domain of E-cadherin upon calcium binding. Eur. J. Biochem. 1994, 223:1019-1026.
8. Tong K.I., Yau P., Overduin M., Bagby S., Porumb T., Takeichi M., Ikura M. Purification and spectroscopic characterization of a recombinant amino-terminal polypeptide fragment of mouse epithelial cadherin. FEBS Lett. 1994, 352:318-322.
9. Shapiro L., Fannon A.M., Kwong P.D., Thompson A., Lehmann M.S., Grubel G., Legrand J.F., Als-Nielsen J., Colman D.R., Hendrickson W.A. Structural basis of cell-cell adhesion by cadherins. Nature 1995, 374:327-337.
10. Aberle H., Schwartz H., Kemler R. Cadherin-catenin complex: protein interactions and their implications for cadherin function. J. Cell Biochem. 1996, 61:514-523.
11. Yagi T., Takeichi M. Cadherin superfamily genes: functions, genomic organization, and neurologic diversity. Genes Dev. 2000, 14:1169-1180.
12. Kemler R. From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion. Trends Genet. 1993, 9:317-321.
13. Jou T.S., Stewart D.B., Stappert J., Nelson W.J., Marrs J.A. Genetic and biochemical dissection of protein linkages in the cadherin-catenin complex. Proc. Natl. Acad. Sci. USA 1995, 92:5067-5071.
14. Uemura K., Kihara T., Kuzuya A., Okawa K., Nishimoto T., Ninomiya H., Sugimoto H., Kinoshita A., Shimohama S. Characterization of sequential N-cadherin cleavage by ADAM10 and PS1. Neurosci. Lett. 2006, 402:278-283.
15. Reiss K., Maretzky T., Ludwig A., Tousseyn T., de Strooper B., Hartmann D., Saftig P. ADAM10 cleavage of N-cadherin and regulation of cell-cell adhesion and beta-catenin nuclear signalling. Embo J. 2005, 24:742-752.
16. Reiss K., Saftig P. The " a disintegrin and metalloprotease" (ADAM) family of sheddases: physiological and cellular functions. Semin. Cell Dev. Biol. 2009, 20:126-137.
17. Haas I.G., Frank M., Veron N., Kemler R. Presenilin-dependent processing and nuclear function of gamma-protocadherins. J. Biol. Chem. 2005, 280:9313-9319.
18. Wakabayashi T., Matsumine A., Nakazora S., Hasegawa M., Iino T., Ota H., Sonoda H., Sudo A., Uchida A. Fbulin-3 negatively regulates chondro. Biochem. Biophys. Res. Commun. 2010, 391:1116-1121.
19. Hatta K., Takeichi M. Expression of N-cadherin adhesion molecules associated with early morphogenetic events in chick development. Nature 1986, 320:447-449.
20. Hatta K., Takagi S., Fujisawa H., Takeichi M. Spatial and temporal expression pattern of N-cadherin cell adhesion molecules correlated with morphogenetic processes of chicken embryos. Dev. Biol. 1987, 120:215-227.
21. Fujimori T., Takeichi M. Disruption of epithelial cell-cell adhesion by exogenous expression of a mutated nonfunctional N-cadherin. Mol. Biol. Cell 1993, 4:37-47.
22. Fujimori T., Miyatani S., Takeichi M. Ectopic expression of N-cadherin perturbs histogenesis in Xenopus embryos. Development 1990, 110:97-104.
23. Haas A.R., Tuan R.S. Chondrogenic differentiation of murine C3H10T1/2 multipotential mesenchymal cells: II. Stimulation by bone morphogenetic protein-2 requires modulation of N-cadherin expression and function. Differentiation 1999, 64:77-89.
24. Oberlender S.A., Tuan R.S. Expression and functional involvement of N-cadherin in embryonic limb chondrogenesis. Development 1994, 120:177-187.
25. Chubinskaya S., Cs-Szabo G., Kuettner K.E. ADAM-10 message is expressed in human articular cartilage. J. Histochem. Cytochem. 1998, 46:723-729.
26. Dallas D.J., Genever P.G., Patton A.J., Millichip M.I., McKie N., Skerry T.M. Localization of ADAM10 and Notch receptors in bone. Bone 1999, 25:9-15.
27. Jin E.J., Park K.S., Kim D., Lee Y.S., Sonn J.K., Jung J.C., Bang O.S., Kang S.S. TGF-beta3 inhibits chondrogenesis by suppressing precartilage condensation through stimulation of N-cadherin shedding and reduction of cRREB-1 expression. Mol. Cells 2010, 29:425-432.
28. Le T.L., Yap A.S., Stow J.L. Recycling of E-cadherin: a potential mechanism for regulating cadherin dynamics. J. Cell Biol. 1999, 146:219-232.