The effect of acute administration of artemisia persia extracts on arterial blood pressure and heart rate in rats

American Journal of Applied Sciences

Volumn 6, Issue 5, 2009, Pages 730-734

  Esmaeili, Farzaneh ^a   Sepehri, Gholamreza ^a   Moshtaghi Kashanian, Ghollam Reza ^a   Khaksari, Mohammad ^a   Salari, Najme ^a   Sepehri, Ehsan ^a  

^a KERMAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Artemisia persia; Blood pressure; Heart rate; Rat

Indexed keywords

EID: 77957244032     PISSN: 15469239     EISSN: 15543641     Source Type: Journal    
DOI: 10.3844/ajas.2009.843.847     Document Type: Article

References (12)

1. Bilia, A.R., D. Lazari, L. Messori, V. Taglioli, C. Temperini and F.F. Vincieri, 2002. Simple and rapid physico-chemical methods to examine action of antimalarial drugs with hemin: Its application to Artemisia annua constituents. Life Sci, 70:769-778.
2. Dell'Eva, R., U. Pfeffer, R. Vene, L. Anfosso, A. Forlani, A. Albini and T. Efferth, 2004. Inhibition of angiogenesis in vivo and growth of Kaposi's sarcoma xenograft tumors by the anti-malarial artesunate. Biochem. Pharmacol., 68: 2359-2366.
3. Chen, H.H., H.J. Zhou and X. Fang, 2003. Inhibition of human cancer cell line growth and human umbilical vein endothelial cell angiogenesis by artemisinin derivatives in vitro. Pharmacol. Res., 48: 231-236.
4. Lee, S.H., M.Y. Lee, H.M. Kang, D.C. Han, K.H. Son, D.C. Yang, N.D. Sung, C.W. Lee, H.M. Kim and B.M. Kwon, 2003. Anti-tumor activity of the farnesyl-protein transferase inhibitors arteminolides, isolated from Artemisa. Bioorgan. Med. Chem., 11: 4545-4549.
5. Kim, D.H., H.K. Na, T.Y. Oh, W.B. Kim and Y.J. Surh, 2004. Eupatilin, a pharmacologically active flavone derived from Artemisia plants, induces cell cycle arrest in ras-transformed human mammary epithelial cells. Biochem. Pharmacol., 68: 1081-1087.
6. Yamahara, J., G. Kobayashi, H. Matsuda, T. Katayama and H. Fujimura, 1989. The effect of scoparone, a coumarin derivative isolated from the Chinese crude drug Artemisiae capillaris flos, on the heart. Chem. Pharmacol. Bull., 37: 1297-1299.
7. Yamahara, J.K.G., 1989. Vascular dilatory action of Artemisia capillaris bud extracts and their active constituent. J. Ethnopharmacol., 26: 129-136.
8. Anfosso, L., T. Efferth, A. Albini and U. Pfeffer, 2006. Microarray expression profiles of angiogenesis-related genes predict tumor cell response to artemisinins. Pharmacogenom. J., 6: 269-278.
9. Zhou, H.J., W.Q. Wang, G.D. Wu, J. Lee and A. Li, 2007. Artesunate inhibits angiogenesis and downregulates vascular endothelial growth factor expression in chronic myeloid leukemia K562 cells. Vasc. Pharmacol., 47: 131-138.
10. Calderone, V., E. Martinotti, B. Baragatti, M.C. Breschi and I. Morelli, 1999. Vascular effects of aqueous crude extracts of Artemisia verlotorum Lamotte (Compositae): In vivo and in vitro pharmacological studies in rats. Phytother. Res., 13: 645-648.
11. Tigno, X.T. and E. Gumila, 2000. In vivo microvascular actions of Artemisia vulgaris L. in a model of ischemia-reperfusion injury in the rat intestinal mesentery. Clin. Hemorheol. Microcircul., 23: 159-165.
12. Tigno, X.T., F. de Guzman and A.M. Flora, 2000. Phytochemical analysis and hemodynamic actions of Artemisia vulgaris L. Clin. Hemorheol. Microcircul., 23: 167-175.