The use of linezolid in the treatment of paediatric patients with infections caused by enterococci including strains resistant to vancomycin

Journal of Antimicrobial Chemotherapy

Volumn 65, Issue 10, 2010, Pages 2267-2270

  Deville, Jaime G ^a   Goldfarb, Johanna ^b   Kaplan, Sheldon L ^c   Equils, Ozlem ^d   Huang, David B ^d   Ang, Jocelyn Y ^e   Salazar, Juan C ^f  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

^c TEXAS CHILDREN S HOSPITAL   (United States)

^d PFIZER INC   (United States)

^e WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f Division of Pediatric Infectious Diseases   (United States)

Author keywords

Children; Enterococcus; Gram positive infections; Resistant infections

Indexed keywords

LINEZOLID;

ABDOMINAL ABSCESS; ABDOMINAL PAIN; ADOLESCENT; ANTIBACTERIAL ACTIVITY; ANTIBIOTIC SENSITIVITY; BACTEREMIA; BACTERIAL STRAIN; BACTERIUM ISOLATION; BLOOD CULTURE; CARCINOID SYNDROME; CHILD; CLINICAL ARTICLE; CLINICAL LABORATORY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DISK DIFFUSION; DRUG EFFICACY; DRUG ERUPTION; DRUG SAFETY; DRUG WITHDRAWAL; ENTEROCOCCAL INFECTION; ENTEROCOCCUS FAECALIS; ENTEROCOCCUS FAECIUM; ENTEROCOCCUS GALLINARUM; EPSILOMETER TEST; FEMALE; GRAM NEGATIVE BACTERIUM; HEADACHE; HUMAN; HYPERTHYROIDISM; INFANT; INFORMED CONSENT; LETTER; MALE; MINIMUM INHIBITORY CONCENTRATION; MULTICENTER STUDY; NAUSEA; NEEDLE BIOPSY; NEWBORN; NONHUMAN; PEDIATRICS; PHASE 3 CLINICAL TRIAL; PHEOCHROMOCYTOMA; PRESCHOOL CHILD; PROSPECTIVE STUDY; PYELONEPHRITIS; SCHOOL CHILD; SIDE EFFECT; SKIN INFECTION; THROMBOCYTE COUNT; TREATMENT DURATION; TREATMENT RESPONSE; URINARY TRACT INFECTION; URINE CULTURE; VANCOMYCIN RESISTANT ENTEROCOCCUS; VOMITING;

ACETAMIDES; ADOLESCENT; ANTI-BACTERIAL AGENTS; CHILD; CHILD, PRESCHOOL; ENTEROCOCCUS; FEMALE; GRAM-POSITIVE BACTERIAL INFECTIONS; HUMANS; INFANT; INFANT, NEWBORN; MALE; OXAZOLIDINONES; TREATMENT OUTCOME; VANCOMYCIN RESISTANCE;

EID: 77957243849     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkq300     Document Type: Letter

References (3)

1. Jones RN, Della-Latta P, Lee LV et al. Linezolid-resistant Enterococcus faecium isolated from a patient without prior exposure to an oxazolidinone: report from the SENTRY Antimicrobial Surveillance Program. Diagn Microbiol Infect Dis 2002; 42: 137-9.
2. Kaplan SL, Deville JG, Yogev R et al. Linezolid versus vancomycin for treatment of resistant Gram-positive infections in children. Pediatr Infect Dis J 2003; 22: 677-86.
3. Clinical and Laboratory Standards Institute. Performance Standards for Antimicrobial Susceptibility Testing: Sixteenth Informational Supplement M100-S16. CLSI, Wayne, PA, USA, 2006.