Diminished cartilage creep properties and increased trabecular bone density following a single, sub-fracture impact of the rabbit femoral condyle

Journal of Orthopaedic Research

Volumn 28, Issue 10, 2010, Pages 1307-1314

  Borrelli Jr , Joseph ^a   Zaegel, Melissa A ^b   Martinez, Mario D ^b   Silva, Matthew J ^b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cartilage; Creep indentation; Impact; Rabbit knee; Trabecular bone

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTICULAR CARTILAGE; BONE DENSITY; CONTROLLED STUDY; EXPERIMENTAL RABBIT; FEMUR CONDYLE; FEMUR FRACTURE; HISTOPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; TRABECULAR BONE; ANIMAL; BIOMECHANICS; BONE DEVELOPMENT; DISEASE MODEL; ELASTICITY; JOINT; MECHANICAL STRESS; OSTEOARTHRITIS; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; RABBIT;

ANIMALS; BIOMECHANICAL PHENOMENA; BONE DENSITY; CARTILAGE, ARTICULAR; DISEASE MODELS, ANIMAL; ELASTICITY; JOINTS; OSTEOARTHRITIS; OSTEOGENESIS; RABBITS; STRESS, MECHANICAL;

EID: 77957205002     PISSN: 07360266     EISSN: 1554527X     Source Type: Journal    
DOI: 10.1002/jor.21122     Document Type: Article

References (19)

1. Borrelli J Jr, Burns ME, Ricci WM, et al. 2002. A method for delivering variable impact stresses to the articular cartilage of rabbit knees. J Orthop Trauma 16:182-188.
2. Borrelli J Jr, Silva MJ, Zaegel MA, et al. 2009. Single high-energy impact load causes post-traumatic OA in young rabbits via a decrease in cellular metabolism. J Orthop Res 27:347-352.
3. Borrelli J Jr, Zhu Y, Burns M, et al. 2004. Cartilage tolerates single impact loads of as much as half the joint fracture threshold. Clin Orthop 426:266-273. (Pubitemid 39167140)
4. Ewers BJ, Weaver BT, Sevensma ET, et al. 2002. Chronic changes in rabbit retro-patellar cartilage and subchondral bone after blunt impact loading of the patellofemoral joint. J Orthop Res 20:545-550. (Pubitemid 34461013)
5. Haut RC, Ide TM, De Camp CE. 1995. Mechanical responses of the rabbit patello-femoral joint to blunt impact. J Biomech Eng 117:402-408.
6. Huser CA, Davies ME. 2006. Validation of an in vitro single-impact load model of the initiation of osteoarthritis-like changes in articular cartilage. J Orthop Res 24:725-732.
7. Lahm A, Kreuz PC, Oberst M, et al. 2006. Subchondral and trabecular bone remodeling in canine experimental osteoarthritis. Arch Orthop Trauma Surg 126:582-587.
8. Milentijevic D, Rubel IF, Liew AS, et al. 2005. An in vivo rabbit model for cartilage trauma: a preliminary study of the influence of impact stress magnitude on chondrocyte death and matrix damage. J Orthop Trauma 19:466-473.
9. Mink JH, Deutsch AL. 1989. Occult cartilage and bone injuries of the knee: detection, classification, and assessment with MR imaging. Radiology 170:823-829.
10. Mow VC, Gibbs MC, Lai WM, et al. 1989. Biphasic indentation of articular cartilage - II. A numerical algorithm and an experimental study. J Biomech 22:853-861.
11. Nakamae A, Engebretsen L, Bahr R, et al. 2006. Natural history of bone bruises after acute knee injury: clinical outcome and histopathological findings. Knee Surg Sports Traumatol Arthrosc 14:1252-1258. (Pubitemid 44800651)
12. Newberry WN, Mackenzie CD, Haut RC. 1998. Blunt impact causes changes in bone and cartilage in a regularly exercised animal model. J Orthop Res 16:348-354.
13. Newberry WN, Zukosky DK, Haut RC. 1997. Subfracture insult to a knee joint causes alterations in the bone and in the functional stiffness of overlying cartilage. J Orthop Res 15:450-455.
14. Athanasiou KA, Rosenwasser MP, Buckwalter JA, et al. 1991. Interspecies comparisons of in situ intrinsic mechanical properties of distal femoral cartilage. J Orthop Res 9:330-340.
15. Natoli RM, Scott CC, Athanasiou KA. 2008. Temporal effects of impact on articular cartilage cell death, gene expression, matrix biochemistry, and biomechanics. Ann Biomed Eng 36:780-792.
16. Jeffrey JE, Thomson LA, Aspden RM. 1997. Matrix loss and synthesis following a single impact load on articular cartilage in vitro. Biochim Biophys Acta 1334:223-232.
17. Radin EL, Rose RM. 1986. Role of subchondral bone in the initiation and progression of cartilage damage. Clin Orthop 213:34-40.
18. Williamson AK, Chen AC, Sah RL. 2001. Compressive properties and function-composition relationships of developing bovine articular cartilage. J Orthop Res 19:1113-1121.
19. Masoud I, Shapiro F, Kent R, et al. 1986. A longitudinal study of the growth of the New Zealand white rabbit: cumulative and biweekly incremental growth rates for body length, body weight, femoral length, and tibial length. J Orthop Res 4:221-231. (Pubitemid 16025835)