Phase i study of topotecan in combination with temozolomide (TOTEM) in relapsed or refractory paediatric solid tumours

European Journal of Cancer

Volumn 46, Issue 15, 2010, Pages 2763-2770

  Rubie, Hervé ^a   Geoerger, Birgit ^b   Frappaz, Didier ^c   Schmitt, Antonin ^d   Leblond, Pierre ^e   Ndiaye, Anna ^b   Aerts, Isabelle ^f   Deley, Marie Cécile Le ^b   Gentet, Jean Claude ^g   Paci, Angelo ^b   Chastagner, Pascal ^h   Dias, Nathalie ^b   Djafari, Latifa ⁱ   Pasquet, Marlne ^d   Chatelut, Etienne ^d   Landman Parker, Judith ^j   Corradini, Nadge ^k   Vassal, Gilles ^b  

^a HÔPITAL DES ENFANTS   (France)

^b INSTITUT GUSTAVE ROUSSY   (France)

^c CENTRE LÉON BÉRARD   (France)

^d INSTITUT CLAUDIUS REGAUD   (France)

^e CENTRE OSCAR LAMBRET   (France)

^f INSTITUT CURIE   (France)

^g TIMONE HOSPITAL   (France)

^h Hôpital Mre Enfants   (France)

ⁱ Schering Plough France ^*  (France)

^j ARMAND TROUSSEAU HOSPITAL   (France)

^k Hôpital des Enfants   (France)

more..

Author keywords

Paediatrics; Phase I; Temozolomide; Topotecan

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; TEMOZOLOMIDE; TOPOTECAN;

ABDOMINAL PAIN; ADOLESCENT; ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANOREXIA; AREA UNDER THE CURVE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; ASTHENIA; BLOOD TOXICITY; CANCER COMBINATION CHEMOTHERAPY; CANCER GRADING; CANCER PATIENT; CANCER RELAPSE; CARCINOMATOUS PERITONITIS; CASE REPORT; CHILD; CHILDHOOD CANCER; CLINICAL ARTICLE; CLINICAL TRIAL; DIARRHEA; DRUG CLEARANCE; DRUG DOSE ESCALATION; EPENDYMOMA; FEMALE; FEVER; GLIOMA; GRANULOSA CELL TUMOR; HUMAN; INFANT; MALE; MAXIMUM TOLERATED DOSE; METASTASIS; MULTICENTER STUDY; MULTIPLE CYCLE TREATMENT; NASOPHARYNX CARCINOMA; NAUSEA; NEUROBLASTOMA; NEUTROPENIA; OSTEOSARCOMA; PHASE 1 CLINICAL TRIAL; PRIORITY JOURNAL; RHABDOMYOSARCOMA; SIDE EFFECT; SOLID TUMOR; THROMBOCYTOPENIA; TREATMENT RESPONSE; VOMITING;

ADOLESCENT; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CHILD; CHILD, PRESCHOOL; DACARBAZINE; HUMANS; INFANT; NEOPLASM RECURRENCE, LOCAL; NEOPLASMS; TOPOTECAN; TREATMENT OUTCOME; YOUNG ADULT;

EID: 77957203514     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejca.2010.05.004     Document Type: Article

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