Y chromosome TSPY copy numbers and semen quality

Fertility and Sterility

Volumn 94, Issue 5, 2010, Pages 1744-1747

  Nickkholgh, Bita ^a   Noordam, Michiel J ^a   Hovingh, Suzanne E ^a   Van Pelt, Ans M M ^a   Van Der Veen, Fulco ^a   Repping, Sjoerd ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

gene copy number; quantitative PCR; semen quality; spermatogenesis; TSPY; Y chromosome

Indexed keywords

GENOMIC DNA; PROTEIN; TESTIS SPECIFIC PROTEIN Y; UNCLASSIFIED DRUG; CELL CYCLE PROTEIN; TSPY1 PROTEIN, HUMAN;

ADULT; ARTICLE; CASE CONTROL STUDY; CELL SPECIFICITY; COHORT ANALYSIS; CONTROLLED STUDY; GENE DOSAGE; HUMAN; MAJOR CLINICAL STUDY; MALE; MALE INFERTILITY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEMEN ANALYSIS; SOUTHERN BLOTTING; SPERMATOGENESIS; SPERMATOZOON COUNT; SPERMATOZOON MOTILITY; Y CHROMOSOME; GENETICS; MIDDLE AGED; RETROSPECTIVE STUDY;

ADULT; CASE-CONTROL STUDIES; CELL CYCLE PROTEINS; CHROMOSOMES, HUMAN, Y; GENE DOSAGE; HUMANS; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; SEMEN ANALYSIS; SPERM COUNT; SPERM MOTILITY;

EID: 77957199173     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2009.09.051     Document Type: Article

References (17)

1. F. Schnieders, T. Dork, J. Arnemann, T. Vogel, M. Werner, and J. Schmidtke Testis-specific protein, Y-encoded (TSPY) expression in testicular tissues Hum Mol Genet 5 1996 1801 1807
2. F. Honecker, H. Stoop, R.R. de Krijger, Y.F. Chris Lau, C. Bokemeyer, and L.H. Looijenga Pathobiological implications of the expression of markers of testicular carcinoma in situ by fetal germ cells J Pathol 203 2004 849 857
3. T. Kido, and Y.F. Lau The human Y-encoded testis-specific protein interacts functionally with eukaryotic translation elongation factor eEF1A, a putative oncoprotein Int J Cancer 123 2008 1573 1585
4. Y. Li, and Y.F. Lau TSPY and its X-encoded homologue interact with cyclin B but exert contrasting functions on cyclin-dependent kinase 1 activities Oncogene 27 2008 6141 6150
5. C. Tyler-Smith, L. Taylor, and U. Muller Structure of a hypervariable tandemly repeated DNA sequence on the short arm of the human Y chromosome J Mol Biol 203 1988 837 848
6. H. Skaletsky, T. Kuroda-Kawaguchi, P.J. Minx, H.S. Cordum, L. Hillier, and L.G. Brown The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes Nature 423 2003 825 837
7. M.A. Jobling, I.C. Lo, D.J. Turner, G.R. Bowden, A.C. Lee, and Y. Xue Structural variation on the short arm of the human Y chromosome: recurrent multigene deletions encompassing Amelogenin Y Hum Mol Genet 16 2007 307 316
8. S. Repping, S.K. van Daalen, L.G. Brown, C.M. Korver, J. Lange, and J.D. Marszalek High mutation rates have driven extensive structural polymorphism among human Y chromosomes Nat Genet 38 2006 463 467
9. S. Repping, H. Skaletsky, L. Brown, S.K. van Daalen, C.M. Korver, and T. Pyntikova Polymorphism for a 1.6-Mb deletion of the human Y chromosome persists through balance between recurrent mutation and haploid selection Nat Genet 35 2003 247 251
10. S.A. Miller, D.D. Dykes, and H.F. Polesky A simple salting out procedure for extracting DNA from human nucleated cells Nucleic Acids Res 16 1988 1215
11. J.S. Zhang, T.L. Yang-Feng, U. Muller, T.K. Mohandas, P.J. de Jong, and Y.F. Lau Molecular isolation and characterization of an expressed gene from the human Y chromosome Hum Mol Genet 1 1992 717 726
12. R. Vodicka, R. Vrtel, L. Dusek, A.R. Singh, K. Krizova, and V. Svacinova TSPY gene copy number as a potential new risk factor for male infertility Reprod Biomed Online 14 2007 579 587
13. V.L. Ernster Nested case-control studies Prevent Med 23 1994 587 590
14. C.J. Biesheuvel, Y. Vergouwe, R. Oudega, A.W. Hoes, D.E. Grobbee, and K.G. Moons Advantages of the nested case-control design in diagnostic research BMC Med Res Method 8 2008 48
15. S. Vijayakumar, D.C. Hall, X.T. Reveles, D.A. Troyer, I.M. Thompson, and D. Garcia Detection of recurrent copy number loss at Yp11.2 involving TSPY gene cluster in prostate cancer using array-based comparative genomic hybridization Cancer Res 66 2006 4055 4064
16. Y.F. Lau, H.W. Lau, and L.G. Komuves Expression pattern of a gonadoblastoma candidate gene suggests a role of the Y chromosome in prostate cancer Cytogenet Genome Res 101 2003 250 260
17. Y. Li, Z.L. Tabatabai, T.L. Lee, S. Hatakeyama, C. Ohyama, and W.Y. Chan The Y-encoded TSPY protein: a significant marker potentially plays a role in the pathogenesis of testicular germ cell tumors Hum Pathol 38 2007 1470 1481