The influence of pre-existing diabetes mellitus on the host immune response and outcome of pneumonia: Analysis of two multicentre cohort studies

Thorax

Volumn 65, Issue 10, 2010, Pages 870-877

  Yende, Sachin ^a   Van Der Poll, Tom ^b   Lee, MinJae ^a,c   Huang, David T ^a   Newman, Anne B ^c   Kong, Lan ^c   Kellum, John A ^a   Harris, Tamara B ^d   Bauer, Doug ^e   Satterfield, Suzanne ^f   Angus, Derek C ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

^c UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^d Demography and Biometry   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTITHROMBIN; BLOOD CLOTTING FACTOR 9; HLA DR ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 6; PLASMINOGEN ACTIVATOR INHIBITOR 1; THROMBIN; THROMBIN ANTITHROMBIN COMPLEX; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR 2;

AGED; ARTICLE; CARDIOVASCULAR DISEASE; COMMUNITY ACQUIRED PNEUMONIA; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE ASSOCIATION; FEMALE; FIBRINOLYSIS; GLUCOSE BLOOD LEVEL; HOSPITALIZATION; HUMAN; IMMUNE RESPONSE; KIDNEY DISEASE; KIDNEY INJURY; MAJOR CLINICAL STUDY; MALE; MORTALITY; POPULATION RESEARCH; PRIORITY JOURNAL; RISK FACTOR;

EID: 77957189516     PISSN: 00406376     EISSN: 14683296     Source Type: Journal    
DOI: 10.1136/thx.2010.136317     Document Type: Article

References (35)

1. Shah BR, Hux JE. Quantifying the risk of infectious diseases for people with diabetes. Diabetes Care 2003;26:510-13.
2. Muller LM, Gorter KJ, Hak E, et al. Increased risk of common infections in patients with type 1 and type 2 diabetes mellitus. Clin Infect Dis 2005;41:281-8.
3. Falguera M, Pifarre R, Martin A, et al. Etiology and outcome of community-acquired pneumonia in patients with diabetes mellitus. Chest 2005;128:3233-9.
4. Kornum JB, Thomsen RW, Riis A, et al. Type 2 diabetes and pneumonia outcomes: a population-based cohort study. Diabetes Care 2007;30:2251-7.
5. Benfield T, Jensen JS, Nordestgaard BG. Influence of diabetes and hyperglycaemia on infectious disease hospitalisation and outcome. Diabetologia 2007;50:549-54. (Pubitemid 46215497)
6. Valdez R, Narayan KM, Geiss LS, et al. Impact of diabetes mellitus on mortality associated with pneumonia and influenza among non-Hispanic black and white US adults. Am J Public Health 1999;89:1715-21. (Pubitemid 29508220)
7. Esper A, Moss M, Martin G. The effect of diabetes mellitus on organ dysfunction with sepsis: an epidemiological study. Crit Care 2009;13:R18.
8. US Renal Data Systems. USRDS 2006 Annual Data Report: Atlas of End-stage Renal Disease in the United States. Bethesda, MD: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, 2007. http://www.usrds.org (accessed Dec 2008).
9. Centers for Disease Control and Prevention (CDC). Prevalence of self-reported cardiovascular disease among persons aged >35 years with diabetes - United States, 1997-2005. MMWR Morb Mortal Wkly Rep 2007;56:1129-32.
10. Timmer JR, Ottervanger JP, Thomas K, et al. Long-term, cause-specific mortality after myocardial infarction in diabetes. Eur Heart J 2004;25:926-31. (Pubitemid 38857866)
11. Lu H, Raptis M, Black E, et al. Influence of diabetes on the exacerbation of an inflammatory response in cardiovascular tissue. Endocrinology 2004;145:4934-9. (Pubitemid 39551110)
12. Krogh-Madsen R, Moller K, Dela F, et al. Effect of hyperglycemia and hyperinsulinemia on the response of IL-6, TNF-{alpha}, and FFAs to low-dose endotoxemia in humans. Am J Physiol Endocrinol Metab 2004;286:E766-72.
13. Reverter JL, Reverter JC, Tassies D, et al. Thrombomodulin and induced tissue factor expression on monocytes as markers of diabetic microangiopathy: a prospective study on hemostasis and lipoproteins in insulin-dependent diabetes mellitus. Am J Hematol 1997;56:93-9.
14. Stegenga ME, van der Crabben SN, Blumer RME, et al. Hyperglycemia enhances coagulation and reduces neutrophil degranulation, whereas hyperinsulinemia inhibits fibrinolysis during human endotoxemia. Blood 2008;112:82-9.
15. Cohen J. The immunopathogenesis of sepsis. Nature 2002;420:885-91.
16. Devaraj S, Dasu MR, Rockwood J, et al. Increased Toll-Like Receptor (TLR) 2 and TLR4 expression in monocytes from patients with Type 1 diabetes: further evidence of a proinflammatory state. J Clin Endocrinol Metab 2008;93:578-83.
17. Levy MM, Fink MP, Marshall JC, et al. 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Crit Care Med 2003;31:1250-6.
18. Barzilay JI, Spiekerman CF, Wahl PW, et al. Cardiovascular disease in older adults with glucose disorders: comparison of American Diabetes Association criteria for diabetes mellitus with WHO criteria. Lancet 1999;354:622-5.
19. Levey AS, Bosch JP, Lewis JB, et al. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group. Ann Intern Med 1999;130:461-70.
20. Yende S, Angus DC, Ali IS, et al. Influence of comorbid conditions on long-term mortality after pneumonia in older people. J Am Geriatr Soc 2007;55:518-25.
21. National Death Index. http://www.cdc.gov/nchs/ndi.htm (accessed Dec 2009).
22. Cowper DC, Kubal JD, Maynard C, et al. A primer and comparative review of major U.S. mortality databases. Ann Epidemiol 2002;12:462-8.
23. Bellomo R, Ronco C, Kellum JA, et al. Acute renal failure - definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Crit Care 2004;8:R204-12.
24. Knaus WA, Wagner DP, Draper EA, et al. The APACHE III prognostic system. Risk prediction of hospital mortality for critically ill hospitalized adults. Chest 1991;100:1619-36.
25. Fine MJ, Auble TE, Yealy DM, et al. A prediction rule to identify low-risk patients with community acquired pneumonia. N Engl J Med 1997;336:243-50.
26. Kellum JA, Kong L, Fink MP, et al. Understanding the inflammatory cytokine response in pneumonia and sepsis: results of the Genetic and Inflammatory Markers of Sepsis (GenIMS) Study. Arch Intern Med 2007;167:1655-63.
27. Yende S, D'Angelo G, Kellum JA, et al. Inflammatory markers at hospital discharge predict subsequent mortality after pneumonia and sepsis. Am J Respir Crit Care Med 2008;177:1242-7.
28. Epstein MP, Lin X, Boehnke M. A tobit variance-component method for linkage analysis of censored trait data. Am J Hum Genet 2003;72:611-20.
29. Hochberg Y, Benjamini Y. More powerful procedures for multiple significance testing. Stat Med 1990;9:811-18.
30. Abosaif NY, Tolba YA, Heap M, et al. The outcome of acute renal failure in the intensive care unit according to RIFLE: model application, sensitivity, and predictability. Am J Kidney Dis 2005;46:1038-48.
31. Mehran R, Aymong ED, Nikolsky E, et al. A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention: development and initial validation. J Am Coll Cardiol 2004;44:1393-9.
32. Ismail N, Becker B, Strzelczyk P, et al. Renal disease and hypertension in non-insulin-dependent diabetes mellitus. Kidney Int 1999;55:1-28.
33. Graves DT, Liu R, Alikhani M, et al. Diabetes-enhanced inflammation and apoptosis - impact on periodontal pathology. J Dent Res 2006;85:15-21.
34. Metersky ML, Ma A, Bratzler DW, et al. Predicting bacteremia in patients with community-acquired pneumonia. Am J Respir Crit Care Med 2004;169:342-7.
35. Joshi N, Caputo GM, Weitekamp MR, et al. Infections in patients with diabetes mellitus. N Engl J Med 1999;341:1906-12.