Reduction in tendon elasticity from unloading is unrelated to its hypertrophy

Journal of Applied Physiology

Volumn 109, Issue 3, 2010, Pages 870-877

  Kinugasa, Ryuta ^a,b   Hodgson, John A ^c   Edgerton, V Reggie ^d   Shin, David D ^e   Sinha, Shantanu ^c  

^a WASEDA UNIVERSITY   (Japan)

^b RIKEN   (Japan)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Magnetic resonance imaging; Stiffness; Stress strain; Young's modulus

Indexed keywords

ACHILLES TENDON; ADOLESCENT; ADULT; ARTICLE; BIOMECHANICS; FEMALE; HUMAN; HYPERTROPHY; IMMOBILIZATION; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; PATHOPHYSIOLOGY; THREE DIMENSIONAL IMAGING; TIME; TORQUE; WEIGHT BEARING; WEIGHTLESSNESS; YOUNG MODULUS;

ACHILLES TENDON; ADOLESCENT; ADULT; BIOMECHANICS; ELASTIC MODULUS; FEMALE; HUMANS; HYPERTROPHY; IMAGING, THREE-DIMENSIONAL; IMMOBILIZATION; MAGNETIC RESONANCE IMAGING, CINE; MALE; TIME FACTORS; TORQUE; WEIGHT-BEARING; WEIGHTLESSNESS SIMULATION; YOUNG ADULT;

EID: 77957172704     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00384.2010     Document Type: Article

References (37)

1. Ahmed IM, Lagopoulos M, McConnell P, Soames RW, Sefton GK. Blood supply of the Achilles tendon. J Orthop Res 16:591-596, 1998.
2. Almeida-Silveira MI, Lambertz D, Perot C, Goubel F. Changes in stiffness induced by hindlimb suspension in rat Achilles tendon. Eur J Appl Physiol 81:252-257, 2000.
3. Bailey AJ. Molecular mechanisms of ageing in connective tissues. Mech Ageing Dev 122:735-755, 2001.
4. Berg HE, Dudley GA, Haggmark T, Ohlsen H, Tesch PA. Effects of lower limb unloading on skeletal muscle mass and function in humans. J Appl Physiol 70:1882-1885, 1991.
5. Binkley JM, Peat M. The effects of immobilization on the ultrastructure and mechanical properties of the medial collateral ligament of rats. Clin Orthop Relat Res 203:301-308, 1986.
6. Chi SW, Hodgson JA, Chen JS, Edgerton VR, Shin DD, Roiz RA, Sinha S. Finite element modeling reveals complex strain mechanics in the aponeuroses of contracting skeletal muscle. J Biomech 43:1243-1250, 2010.
7. Christensen B, Dyrberg E, Aagaard P, Kjaer M, Langberg H. Shortterm immobilization and recovery affect skeletal muscle but not collagen tissue turnover in humans. J Appl Physiol 105:1845-1851, 2008.
8. Danielsen CC, Andreassen TT. Mechanical properties of rat tail tendon in relation to proximal-distal sampling position and age. J Biomech 21:207-212, 1988.
9. de Boer MD, Maganaris CN, Seynnes OR, Rennie MJ, Narici MV. Time course of muscular, neural and tendinous adaptations to 23 day unilateral lower-limb suspension in young men. J Physiol 583:1079-1091, 2007.
10. Delgado-Lezama R, Raya JG, Munoz-Martinez EJ. Methods to find aponeurosis and tendon stiffness and the onset of muscle contraction. J Neurosci Methods 78:125-132, 1997.
11. Finni T, Hodgson JA, Lai AM, Edgerton VR, Sinha S. Nonuniform strain of human soleus aponeurosis-tendon complex during submaximal voluntary contractions in vivo. J Appl Physiol 95:829-837, 2003.
12. Heinemeier KM, Olesen JL, Haddad F, Schjerling P, Baldwin KM, Kjaer M. Effect of unloading followed by reloading on expression of collagen and related growth factors in rat tendon and muscle. J Appl Physiol 106:178-186, 2009.
13. Kinugasa R, Shin D, Yamauchi J, Mishra C, Hodgson JA, Edgerton VR, Sinha S. Phase-contrast MRI reveals mechanical behavior of superficial and deep aponeuroses in human medial gastrocnemius during isometric contraction. J Appl Physiol 105:1312-1320, 2008.
14. Kotani Y, Cunningham BW, Cappuccino A, Kaneda K, McAfee PC. The effects of spinal fixation and destabilization on the biomechanical and histologic properties of spinal ligaments. An in vivo study. Spine (Phila Pa 1976) 23:672-683, 1998.
15. Kubo K, Akima H, Ushiyama J, Tabata I, Fukuoka H, Kanehisa H, Fukunaga T. Effects of resistance training during bed rest on the viscoelastic properties of tendon structures in the lower limb. Scand J Med Sci Sports 14:296-302, 2004. (Pubitemid 39360654)
16. Kubo K, Kawakami Y, Kanehisa H, Fukunaga T. Measurement of viscoelastic properties of tendon structures in vivo. Scand J Med Sci Sports 12:3-8, 2002.
17. Lee HD, Finni T, Hodgson JA, Lai AM, Edgerton VR, Sinha S. Soleus aponeurosis strain distribution following chronic unloading in humans: an in vivo MR phase-contrast study. J Appl Physiol 100:2004-2011, 2006.
18. Maganaris CN, Paul JP. Load-elongation characteristics of in vivo human tendon and aponeurosis. J Exp Biol 203:751-756, 2000.
19. Magnusson SP, Hansen P, Aagaard P, Brond J, Dyhre-Poulsen P, Bojsen-Moller J, Kjaer M. Differential strain patterns of the human gastrocnemius aponeurosis and free tendon, in vivo. Acta Physiol Scand 177:185-195, 2003.
20. Magnusson SP, Narici MV, Maganaris CN, Kjaer M. Human tendon behaviour and adaptation, in vivo. J Physiol 586:71-81, 2008.
21. Matsumoto F, Trudel G, Uhthoff HK, Backman DS. Mechanical effects of immobilization on the Achilles' tendon. Arch Phys Med Rehabil 84:662-667, 2003.
22. Nakagawa Y, Totsuka M, Sato T, Fukuda Y, Hirota K. Effect of disuse on the ultrastructure of the achilles tendon in rats. Eur J Appl Physiol Occup Physiol 59:239-242, 1989.
23. Narici MV, Maganaris CN, Reeves ND, Capodaglio P. Effect of aging on human muscle architecture. J Appl Physiol 95:2229-2234, 2003.
24. Paavola M, Kannus P, Jarvinen TA, Khan K, Jozsa L, Jarvinen M. Achilles tendinopathy. J Bone Joint Surg Am 84:2062-2076, 2002. (Pubitemid 35283376)
25. Patterson-Kane JC, Wilson AM, Firth EC, Parry DA, Goodship AE. Comparison of collagen fibril populations in the superficial digital flexor tendons of exercised and nonexercised thoroughbreds. Equine Vet J 29:121-125, 1997.
26. Rack PM, Westbury DR. Elastic properties of the cat soleus tendon and their functional importance. J Physiol 347:479-495, 1984.
27. Reeves ND, Maganaris CN, Ferretti G, Narici MV. Influence of 90-day simulated microgravity on human tendon mechanical properties and the effect of resistive countermeasures. J Appl Physiol 98:2278-2286, 2005.
28. Schulze K, Gallagher P, Trappe S. Resistance training preserves skeletal muscle function during unloading in humans. Med Sci Sports Exerc 34:303-313, 2002.
29. Scott SH, Loeb GE. Mechanical properties of aponeurosis and tendon of the cat soleus muscle during whole-muscle isometric contractions. J Morphol 224:73-86, 1995.
30. Shin D, Finni T, Ahn S, Hodgson JA, Lee HD, Edgerton VR, Sinha S. Effect of chronic unloading and rehabilitation on human Achilles tendon properties: a velocity-encoded phase-contrast MRI study. J Appl Physiol 105:1179-1186, 2008.
31. Shin D, Finni T, Ahn S, Hodgson JA, Lee HD, Edgerton VR, Sinha S. In vivo estimation and repeatability of force-length relationship and stiffness of the human achilles tendon using phase contrast MRI. J Magn Reson Imaging 28:1039-1045, 2008.
32. Siegel S, Castellan Jr NJ. Nonparametric Statistics for the Behavioral Sciences. New York: McGraw-Hill, 1988.
33. Sinha S, Hodgson JA, Finni T, Lai AM, Grinstead J, Edgerton VR. Muscle kinematics during isometric contraction: development of phase contrast and spin tag techniques to study healthy and atrophied muscles. J Magn Reson Imaging 20:1008-1019, 2004.
34. Trestik CL, Lieber RL. Relationship between Achilles tendon mechanical properties and gastrocnemius muscle function. J Biomech Eng 115:225-230, 1993.
35. Tsuchida T, Yasuda K, Kaneda K, Hayashi K, Yamamoto N, Miyakawa K, Tanaka K. Effects of in situ freezing and stress-shielding on the ultrastructure of rabbit patellar tendons. J Orthop Res 15:904-910, 1997.
36. Voigt M. Muscle-Tendon Elasticity In Vivo and Its Significance for Human Perfomance. Copenhagen: University of Copenhagen, 1994.
37. Zajac FE. Muscle and tendon: properties, models, scaling, and application to biomechanics and motor control. Crit Rev Biomed Eng 17:359-411, 1989.