Inhibition of the alternative pathway of complement activation reduces inflammation in experimental autoimmune uveoretinitis

European Journal of Immunology

Volumn 40, Issue 10, 2010, Pages 2870-2881

  Chen, Mei ^a   Muckersie, Elizabeth ^b   Luo, Chang ^a   Forrester, John V ^b   Xu, Heping ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^b UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

Complement; Complement receptor; Experimental autoimmune uveoretinitis; Retina

Indexed keywords

ALTERNATIVE COMPLEMENT PATHWAY C3 C5 CONVERTASE; COMPLEMENT COMPONENT C3D; COMPLEMENT RECEPTOR; COMPLEMENT RECEPTOR OF THE IMMUNOGLOBULIN SUPERFAMILY FUSION PROTEIN; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 6; NITRIC OXIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; COMPLEMENT ACTIVATION; COMPLEMENT ALTERNATIVE PATHWAY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG ACTIVITY; EXPERIMENTAL AUTOIMMUNE UVEORETINITIS; FEMALE; HISTOPATHOLOGY; LYMPHOCYTE PROLIFERATION; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; UVEORETINITIS;

ANIMALS; AUTOIMMUNITY; COMPLEMENT ACTIVATION; COMPLEMENT C3B; COMPLEMENT FACTOR B; COMPLEMENT PATHWAY, ALTERNATIVE; CYTOKINES; DISEASE MODELS, ANIMAL; FEMALE; IMMUNOHISTOCHEMISTRY; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; NITRIC OXIDE SYNTHASE TYPE II; RECEPTORS, COMPLEMENT; RETINITIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; T-LYMPHOCYTES;

EID: 77957172328     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201040323     Document Type: Article

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