Chapter 24. Inhibition of Matrix Metalloproteinases.

Annual Reports in Medicinal Chemistry

Volumn 31, Issue C, 1996, Pages 231-240

  Hagmann, William K ^a   Lark, Michael W ^b   Becker, Joseph W ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b SmithKline Beecham Pharmaceuticals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 77957150716     PISSN: 00657743     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0065-7743(08)60463-7     Document Type: Article

References (111)

1. Alexander C.W., and Werb Z. In: Hay E.D. (Ed). Cell Biology of the Extracellular Matrix. 2nd Edn. (1991), Plenum Press, New York 255
2. Matrisian L.M. BioEssays 14 (1992) 455
3. Lohmander S. Arch. Biochem. Biophys. 186 (1987) 93
4. Armstrong P.W., Moe G.W., Howard R.J., Grima E.A., and Cruz T.F. Exp. Cardiol. 10 (1994) 214
5. Ray J.M., and Stetler-Stevenson W.G. EMBO J. 14 (1995) 908
6. Galis Z.S., Sukhova G.K., Lark M.W., and Libby P. J. Clin. Invest. 94 (1994) 2493
7. Lohmander L.S., Hoerrner L.A., and Lark M.W. Arthrit. Rheum. 36 (1993) 181
8. Walakovits L.A., Moore V.L., Bhardwaj N., Gallick G.S., and Lark M.W. Arthrit. Rheum. 35 (1992) 35
9. Tezuka K., Nemato K., Tezuka Y., Sato T., Ikeda Y., Kobori M., Kawashima H., Eguchi H., Hakeda Y., and Kumegawa M. J. Biol. Chem. 269 (1994) 15006
10. Haerian A., Adonogianaki E., Mooney J., Docherty J.P., and Kinane D.F. J. Clin. Periodontal. 22 (1995) 505
11. Perides G., Asher R.A., Lark M.W., and Bignami A. Biochem. J. 312 (1995) 377
12. Murphy G. AAS 35: Progress in Inflammation Research and Therapy (1991), Verlag Birkhauser, Basel 69
13. Apte S.S., Olsen B.R., and Murphy G. J. Biol. Chem. 270 (1995) 14313
14. Murphy G.M., Cockett M.I., Stephens P.E., Smith B.J., and Docherty A.J.P. Biochem. J. 248 (1987) 265
15. Quantin B., Murphy G., and Breathnach R. Biochem. 28 (1989) 5327
16. Sato H., Takino T., Okada Y., Cao J., Shinagawa A., Yamamoto E., and Seiki M. Nature 370 (1994) 61
17. Will B., and Hinzmann B. Eur. J. Biochem. 231 (1995) 602
18. Takino T., Sato H., Shinagawa A., and Seiki M. J. Biol. Chem. 270 (1995) 23013
19. Puente X.S., Pondas A.M., Llano E., Velasco G., and Lopez-Olin C. Canc. Res. 56 (1996) 944
20. McGeehan G.M., Becherer J.D., Blast Jr. R.C., Boyer C.M., Champion B., Connolly K.M., Conway J.G., Furdon P., Karp S., Kidao S., McElroy A.B., Nichols J., Pryzwansky K.M., Schoenen F., Sekut L., Truesdale A., Verghese M., Warner J., and Ways J.P. Nature 370 (1994) 558
21. Mullberg J., Durie F.H., Otten-Evans C., Alderson M.R., Rose-John S., Cosman D., Black R.A., and Mohler K.M. J. Immunol. 155 (1995) 5198
22. Kayagaki N., Kawasaki A., Ebata T., Ohmoto H., Ikeda S., Inoue S., Yoshino K., Okumura K., and Yagita H. J. Exp. Med. 182 (1995) 1777
23. Ramachandran R., and Sen I. Biochem. 34 (1995) 12645
24. Couet J., Sar S., Jolivet A., Hai M.-T.V., Milgrom E., and Misrah M. J. Biol. Chem. 271 (1996) 4545
25. G. Christie and B.J. Weston PCT WO 96/02240 (1996).
26. Okada Y., Harris E.D., and Nagase H. Biochem. J. 254 (1988) 731
27. Okada Y., and Nakanishi I. FEBS. Lett. 249 (1989) 353
28. Nagase H., Enghild J.J., Suzuki K., and Salvesen G. Biochem. 29 (1990) 5783
29. Koklitis P.A., Murphy G., Sutton C., and Angal S. Biochem. J. 276 (1991) 217
30. Murrell G.A.C., Jang D., and Williams R.J. Biochem. Biophys. Res. Comm. 206 (1995) 15
31. Okada Y., Konomi H., Yada T., Kimata K., and Nagase H. FEBS. Lett. 244 (1989) 473
32. Okada Y., Nagase H., and Harris E.D. J. Biol. Chem. 261 (1986) 14245
33. Marcy A.I., Eiberger L.L., Harrison R., Chan H.K., Hutchinson N.I., Hagmann W.K., Cameron P.M., Boulton D.A., and Hermes J.D. Biochem. 30 (1991) 6476
34. Ye Q.-Z., Johnson L.L., Nordan I., Hupe D., and Hupe L. J. Med. Chem. 37 (1994) 206
35. Becker J.W., Marcy A.I., Rokosz L.L., Axel M.G., Burbaum J.J., Fitzgerald P.M.D., Cameron P.M., Esser C.K., Hagmann W.K., Hermes J.D., and Springer J.P. ProteinSci. 4 (1995) 1966
36. Gooley P.R., O'Connell J.F., Marcy A.I., Cuca G.C., Salowe S.P., Bush B.L., Hermes J.D., Esser C.K., Hagmann W.K., Springer J.P., and Johnson B.A. NatureStruct. Biol. 1 (1994) 111
37. Borkakoti N., Winkler F.K., Williams D.H., Darcy A., Broadhurst M.J., Brown P.A., Johnson W.H., and Murray E.J. NatureStruct. Biol. 1 (1994) 106
38. Lovejoy B., Cleasby A., Hassell A.M., Longley K., Luther M.A., Weigl D., McGeehan G., McElroy A.B., Drewry D., Lambert M.H., and Jordan S.R. Science 263 (1994) 375
39. Lovejoy B., Hassell A.M., Luther M.A., Weigl D., and Jordan S.R. Biochem. 33 (1994) 8207
40. Spurlino J.C., Smallwood A.M., Carlton D.D., Banks T.M., Vavra K.J., Johnson J.S., Cook E.R., Falvo J., Wahl R.C., Pulvino T.A., Wendoloski J.J., and Smith D.L. Proteins: Struct. Func. Genet. 19 (1994) 98
41. Bode W., Reinemer P., Huber R., Kleine T., Schnierer S., and Tschesche H. EMBO J. 13 (1994) 1263
42. Stams T., Spurlino J.C., Smith D.L., Wahl R.C., Ho T.F., Qoronfleh M.W., Banks T.M., and Rubin B. NatureStruct. Biol. 1 (1994) 119
43. Browner M.F., Smith W.W., and Castelhano A.L. Biochem. 34 (1995) 6602
44. Grams F., Crimmin M., Hinnes L., Huxley P., Pieper M., Tschesche H., and Bode W. Biochem. 34 (1995) 14012
45. Grams F., Reinemer P., Powers J.C., Kleine T., Pieper M., Tschesche H., Huber R., and Bode W. Eur. J. Biochem. 228 (1995) 830
46. Van Doren S.R., Kurochkin A.V., Hu W.D., Ye Q.Z., Johnson L.L., Hupe D.J., and Zuiderweg E.R.P. ProteinSci. 4 (1995) 2487
47. Faber H.R., Groom C.R., Baker H.M., Morgan W.T., Smith A., and Baker E.N. Structure 3 (1995) 551
48. Li J., Brick P., O'Hare M.C., Skarzynski T., Lloyd L.F., Curry V.A., Clark I.M., Bigg H.F., Hazleman B.L., Cawston T.E., and Blow D.M. Structure 3 (1995) 541
49. Libson A.M., Gittis A.G., Collier I.E., Marmer B.L., Goldberg G.I., and Lattman E.E. NatureStruct. Biol. 2 (1995) 938
50. Gohlke U., Gomis-Rüth F.-X., Crabbe T., Murphy G., Docherty A.J.P., and Bode W. FEBS Lett. 378 (1996) 126
51. Bode W., Gomis-Rüth F.X., and Stockler W. FEBSLett. 331 (1993) 134
52. Gomis-Rüth F.X., Kress L.F., Kellermann J., Mayr I., Lee X., Huber R., and Bode W. J. Molec. Biol. 239 (1994) 513
53. Stöcker W., Grams F., Baumann U., Reinemer P., Gomis-Rüth F.X., McKay D.B., and Bode W. ProteinSci. 4 (1995) 823
54. Matthews B.H. Acct. Chem. Res. 21 (1988) 333
55. Johnson W.H., Roberts N.A., and Borkakoti N. J. Enz. Inhib. 2 (1987) 1
56. Henderson B., Docherty A.J.P., and Beeley N.R.A. Drugs Future 15 (1990) 495
57. Johnson W.H. Drug News Perspective 3 (1990) 453
58. Wahl R.C., Dunlap R.P., and Morgan B.A. Ann. Rep. Med. Chem. 25 (1990) 177
59. Schwartz M.A., and Van Wart H.E. In: Ellis G.P., and Luscombe D.K. (Eds). Progress in Medicinal Chemistry 29 (1992), Elsevier Sci. Publ., London 271 Ch. 8
60. Beeley N.R.A., Ansell P.R.J., and Docherty A.J.P. Curr. Opin. Ther. Patents 4 (1994) 7
61. Brown P.A. Osteoarthritis: Advances in Pathology, Diagnosis and Treatment (1994), Internal. Bus. Commun., London 1
62. Brown P.D. Adv. Enz. Regul. 35 (1995) 293
63. Morphy J.R., Millican T.A., and Porter J.R. Curr. Med. Chem. 2 (1995) 743
64. Beckett P.D., Davidson A.H., Drummond A.H., Huxley P., and Whittaker M. DrugDesignToday 1 (1996) 16
65. Watson S.A., Morris T.M., Robinson G., Crimmin M.J., Brown P.D., and Hardcastle J.D. Canc. Res. 55 (1995) 3629
66. Sledge G.W., Qulali M., Goulet R., Bone E.A., and Fife R. J. Natl. Canc. Inst. 87 (1995) 1546
67. Scrip 2041 (1995) 7
68. Scrip 2084 (1995) 23
69. Scrip 1775 (1992) 24
70. Hewson A.K., Smith T., Leonard J.P., and Cuzner M.L. Inflamm. Res. 44 (1995) 345
71. M.J. Broadhurst, P.A. Brown and W.H. Johnson, PCT WO 95/33709 (1995).
72. Chapman K.T., Kopka I.E., Durette P.L., Esser C.K., Lanza T.J., Izquierdo-Martin M., Niedzwiecki L., Chang B., Harrison R.K., Kuo D.W., Lin T.-Y., Stein R.L., and Hagmann W.K. J. Med. Chem. 36 (1993) 4293
73. Esser C.K., Kopka I.E., Durette P.L., Harrison R.K., Niedzwiecki L.M., Izquierdo-Martin M., Stein R.L., and Hagmann W.K. Bioorg. Med. Chem. Lett. 5 (1995) 539
74. Sahoo S.P., Caldwell C.G., Chapman K.T., Durette P.L., Esser C.K., Polo S.A., Sperow K.M., Niedzwiecki L.M., Izquierdo-Martin M., Chang B.C., Harrison R.K., Stein R.L., MacCoss M., and Hagmann W.K. Bioorg. Med. Chem. Lett. 5 (1995) 2441
75. Chapman K.T., Wales J., Sahoo S.P., Niedzwiecki L.M., Izquierdo-Martin M., Chang B.C., Harrison R.K., Stein R.L., and Hagmann W.K. Bioorg. Med. Chem. Lett. 6 (1996) 329
76. Xue C.-B., He X., Roderick J., Degrado W.F., Decicco C., and Copeland R.A. Bioorg. Med. Chem. Lett. 6 (1996) 379
77. Brown F.K., Brown P.J., Bickett D.M., Chambers C.L., Davies H.G., Deaton D.N., Drewry D., Foley M., McElroy A.B., Gregson M., McGeehan G.M., Myers P.L., Norton D., Salovich J., Schoenen F.J., and Ward P. J. Med. Chem. 37 (1994) 674
78. Chapman K.T., Durette P.L., Caldwell C.G., Sperow K.M., Niedzwiecki L.M., Harrison R.K., Saphos C., Christen A.J., Olszewski J.M., Moore V.L., MacCoss M., and Hagmann W.K. Bioorg. Med. Chem. Lett. 6 (1996) 803
79. K.M. Donahue, B.J. Cronin, B.P. Jones, P.G. Mitchell, L. Lopresti-Morrow, J.A. Ragan, L.M. Reeves, J. P Rizzi, R.P. Robinson and S.A. Yocum, Abstracts of Papers, 211th ACS Nat'l. Mtg., New Orleans, LA, March 1996, Abs. # MEDI 212.
80. A. Miller, P.R. Beckett, F.M. Martin and M. Whittaker, PCT WO 95/32944 (1995).
81. Caldwell C.G., Sahoo S.P., Polo S.A., Eversole R.R., Lanza T.J., Mills S.G., Niedzwiecki L.M., Izquierdo-Martin M., Chang B.C., Harrison R.K., Kuo D.W., Lin T.-Y., Stein R.L., Durette P.L., and Hagmann W.K. Bioorg. Med. Chem. Lett. 6 (1996) 323
82. Hughes I., Harper G.P., Karran E.H., Markwell R.E., and Miles-Williams A.J. Bioorg. Med. Chem. Lett. 5 (1995) 3039
83. J. Montana, J. Dickens, D.A. Owen and A.D. Baxter, PCT WO 95/13289 (1995).
84. M.A. Schwartz and H. Van Wart, PCT WO 95/9620 (1995).
85. Bird J., Harper G.P., Hughes I., Hunter D.J., Karran E.H., Markwell P.E., Miles-Williams A.J., Rahman S.S., and Ward R.W. Bioorg. Med. Chem. Lett. 5 (1995) 2593
86. Castelhano A.L., Billedeau R., Dewdney N., Donnelly S., Horne S., Kurz L.J., Liak T.J., Martin R., Uppington R., Yuan Z., and Krantz A. Bioorg. Med. Chem. Lett. 5 (1995) 1415
87. M. Sakamoto, T. Imaoka, M. Motoyama, Y. Yamamoto and H. Takasu PCT WO 94/21612 (1994).
88. M. Nitta, R. Hirayama and M. Yamamoto, Jap. Pat. Applic. JP7304770 (1995).
89. M. Nitta and M. Yamamoto, Jap. Pat. Applic. JP7304746 (1995).
90. J.S. Frazee, J.G. Gleason and B.W. Metcalf, PCT WO95/23790 (1995).
91. C. P DeCicco, I.C. Jacobson, R.L. Magolda, D.J. Nelson and R.J. Cherney, PCT WO95/29892 (1995).
92. M.J. Broadhurst, P.A. Brown and W.H. Johnson, PCT WO 95/33731 (1995).
93. Tanzawa K., Ishii M., Ogita T., and Shimada K. J. Antibiotics 45 (1992) 1733
94. Tamaki K., Tanzawa K., Kurihara S., Oikawa T., Monma S., Shimada K., and Sugimura Y. Chem. Pharm. Bull. 43 (1995) 1883
95. Nugiel D.A., Jacobs K., DeCicco C.P., Nelson D.J., Copeland R.A., and Hardman K.D. Bioorg. Med. Chem. Lett. 5 (1995) 3053
96. M.J. Broadhurst, P.A. Brown and W.H. Johnson, EPA 0684240A1 (1995)
97. L.J. MacPherson and D.T. Parker, U.S. Patent 5, 455, 258 (1995).
98. O'Byme E.M., Parker D.T., Roberts E.D., Goldberg R.L., MacPherson L.J., Blancuzzi V., Wilson D., Singh H.N., Ludewig R., and Ganu V.S. Inflamm. Res. 44 suppl. 2 (1995) S177
99. Spirito S., Doughty J., O'Byrne E., Ganu V., and Goldberg R.L. Inflamm. Res. 44 suppl. 2 (1995) S131
100. L.J. MacPherson, D.T. Parker and A.Y. Jeng, PCT WO 96/00214 (1996).
101. A. Miller, M. Whittaker and R.P. Beckett, PCT WO 95/35275 (1995).
102. A. Miller, M. Whittaker and R.P. Beckett, PCT WO 95/35276 (1995).
103. Mohler K.M., Sleath P.R., Fitzner J.N., Cerretti D.P., Alderson M., Kerwar S.S., Torrance D.S., Otten-Evans C., Greenstreet T., Weerawarna K., Kronheim S.R., Peteren M., Gerhart M., Kozlosky C.J., March C.J., and Black R.A. Nature 370 (1994) 218
104. Gearing A.J.H., Beckett P., Christodoulou M., Churchill M., Clements J., Davidson A.H., Drummond A.H., Galloway W.A., Gilbert R., Gordon J.L., Leber T.M., Mangan M., Miller K., Nayee P., Owen K., Patel S., Thomas W., Wells G., Wood L.M., and Wooley K. Nature 370 (1994) 555
105. Crowe P.D., Walter B.N., Mohler K.M., Otten-Evans C., Black R.A., and Ware C.F. J. Exp. Med. 181 (1995) 1205
106. Hollander A.P., Pidoux I., Reiner A., Rorabeck C., Bourne R., and Poole A.R. J. Clin. Invest. 96 (1995) 2859
107. Lark M.W., Bayne E.K., and Lohmander L.S. Acta Orthp. Scand. 66 (1995) 92
108. Lark M.W., Gordy J.T., Weidner J.R., Ayala J., Kimura J.H., Williams H.R., Mumford R.A., Flannery C.R., Carlson S.S., Iwata M., and Sandy J.D. J. Biol. Chem. 270 (1995) 2550
109. Wang X., Fu X., Brown P.D., Crimmin M.J., and Hoffman R.M. Can. Res. 54 (1994) 4726
110. Conway J.G., Wakefield J.A., Brown R.H., Marron B.E., Sekut L., Stimpson S.A., McElroy A., Menius J.A., Jeffreys J.J., Clark R.L., McGeehan G.M., and Connolly K.M. J. Exp. Med. 182 (1995) 449
111. Prata M.A. Inflam. Res. 44 (1995) 458