Structural and Functional Characteristics of the Dopamine D4 Receptor

Advances in Pharmacology

Volumn 42, Issue C, 1997, Pages 486-490

  Van Tol, Hubert H M ^a  

^a CENTRE FOR ADDICTION AND MENTAL HEALTH   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 77957141456     PISSN: 10543589     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S1054-3589(08)60794-2     Document Type: Article

References (13)

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2. Seeman P., and Van Tol H.H.M. Dopamine receptors. Trends Pharmacol. Sci 15 (1994) 264-270
3. Van Tol H.H.M., and Seeman P. The dopamine D4 receptor: A novel site for antipsychotic action. Clin. Neuropharmacol. 18 Suppl 1 (1995) S143-S153
4. Van Tol H.H.M., Wu C.M., Guan H.C., Ohara K., Bunzow J.R., Civelli O., Kennedy J., Seeman P., Niznik H.B., and Jovanovic V. Multiple dopamine D4 receptor variants in rhe human population. Nature 358 (1992) 149-152
5. Lichter J.B., Barr C.L., Kennedy J.L., Van Tol H.H.M., Kidd K.K., and Livak K.J. A hypervariable segment in the human dopamine receptor D4 (DRD4) gene. Hum. Mol. Genet 2 (1993) 767-773
6. Asghari V., Schoots O., Van Kats S., Ohara K., Jovanovic V., Guan H.C., Bunzow J.R., Petronis A., and Van Tol H.H.M. The dopamine D4 receptor repeat: Analysis of different native and mutant forms of the human and rat gene. Mol. Pharmacol 46 (1994) 364-373
7. Asghar V., Sanyal S., Buchwaldt S., Paterson A., Jovanovic V., and Van Tol H.H.M. Modulation of intracellular cyclic AMP levels by different human dopamine D4 receptor variants. J. Neurochem 65 (1995) 1157-1165
8. Liu I.S.C., Seeman P., Sanyal S., Ulpian C., Rodgers-Johnson P.E.B., Serjeant G.R., and Van Tol H.H.M. Dopamine D4 receptor variant in Africans, D4Valine194Glycine, is insensitive to dopamine and clozapine. Report of a homozygous individual. Am. J. Med. Genet 61 (1996) 277-282
9. Schoots O., Sanyal S., Guan H.C., Jovanovic V., and Van Tol H.H.M. Cryptic initiation at the human D4 receptor reveals a functional role for the amino-terminus. Biochemistry 35 (1996) 3614-3618
10. Benjamin J., Li L., Patterson C., Greenberg B.D., Murphy D.L., and Hamer D.H. Population and familial association between the D4 dopamine receptor gene and measures of novelty seeking. Nat. Genet 12 (1996) 81-84
11. Ebstein R.P., Novick O., Umansky R., Priel B., Osher Y., Blaine D., Bennett E.R., Nemanov L., Katz M., and Belmaker R.H. Dopamine D4 receptor (D4DR) exon III polymorphism associated with the human personality trait of novelty seeking. Nat. Genet 12 (1996) 78-80
12. LaHoste G.J., Swanson J.M., Wigal S.B., Glabe C., Wigal T., King N., and Kennedy J.L. Dopamine D4 receptor gene polymorphism in association with attention deficit hyperactivity disorder. Mol. Psychiatry 1 (1996) 121-124
13. Shaikh S., Collier D., Kenvin R.W., Pilowsky L.S., Gill M., Xu X.M., and Thornton A. Dopamine D4 subtypes and response to clozapine. Lancet 341 (1993) 116