Pituitary adenomas in childhood, adolescence and young adulthood: Presentation, management, endocrine and metabolic outcomes

European Journal of Endocrinology

Volumn 163, Issue 4, 2010, Pages 515-522

  Steele, Caroline A ^a   MacFarlane, Ian A ^a   Blair, Joanne ^b   Cuthbertson, Daniel J ^a   Didi, Mohammed ^b   Mallucci, Conor ^c   Javadpour, Mohsen ^c   Daousi, Christina ^a  

^a ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST   (United Kingdom)

^b ALDER HEY CHILDREN'S NHS FOUNDATION TRUST   (United Kingdom)

^c WALTON CENTRE FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIHYPERTENSIVE AGENT; BROMOCRIPTINE; CABERGOLINE; DESMOPRESSIN; GROWTH HORMONE; HYDROCORTISONE; PROLACTIN; QUINAGOLIDE; SEX HORMONE; TETRAHYDROLIPSTATIN; THYROXINE; DOPAMINE RECEPTOR STIMULATING AGENT;

ACROMEGALY; ACTH SECRETING ADENOMA; ADOLESCENCE; ADOLESCENT; ADULT; ADULTHOOD; ARTICLE; BODY MASS; CANCER RADIOTHERAPY; CARDIOVASCULAR RISK; CHILD; CHILDHOOD; CLINICAL ARTICLE; CUSHING DISEASE; DRUG SUBSTITUTION; DRUG WITHDRAWAL; DYSLIPIDEMIA; ENDOCRINE SURGERY; FEMALE; FEMALE INFERTILITY; FOLLOW UP; GROWTH HORMONE DEFICIENCY; GROWTH HORMONE SECRETING ADENOMA; HORMONE SUBSTITUTION; HUMAN; HYPOPHYSIS ADENOMA; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONFUNCTIONING PITUITARY ADENOMA; OBESITY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROLACTIN BLOOD LEVEL; PROLACTINOMA; RETROSPECTIVE STUDY; SCHOOL CHILD; UNITED KINGDOM; UNSPECIFIED SIDE EFFECT; WEIGHT GAIN; COMPLICATION; MIDDLE AGED; PITUITARY ACTH HYPERSECRETION; PITUITARY NEOPLASMS; RISK FACTOR; YOUNG ADULT;

ADOLESCENT; ADULT; CHILD; DOPAMINE AGONISTS; FEMALE; HUMANS; MALE; MIDDLE AGED; PITUITARY ACTH HYPERSECRETION; PITUITARY NEOPLASMS; PROLACTINOMA; RETROSPECTIVE STUDIES; RISK FACTORS; YOUNG ADULT;

EID: 77957135657     PISSN: 08044643     EISSN: 1479683X     Source Type: Journal    
DOI: 10.1530/EJE-10-0519     Document Type: Article

References (41)

1. Lafferty AR & Chrousos GP. Pituitary tumors in children and adolescents. Journal of Clinical Endocrinology and Metabolism 1999 84 4317-4323. (doi:10.1210/jc.84.12.4317)
2. Webb C & Prayson RA. Pediatric pituitary adenomas. Archives of Pathology and Laboratory Medicine 2008 132 77-80.
3. Mehrazin M. Pituitary tumors in children: clinical analysis of 21 cases. Child's Nervous System 2007 23 391-398. (doi:10.1007/s00381-006-0259-4) (Pubitemid 46766855)
4. Mukai K, Seljeskog EL & Dehner LP. Pituitary adenomas in patients under 20 years old. A clinicopathological study of 12 cases. Journal of Neuro-Oncology 1986 4 79-89. (doi:10.1007/BF02158007)
5. Lee AG, Sforza PD, Fard AK, Repka MX, Baskin DS & Dauser RC. Pituitary adenoma in children. Journal of Neuro-Ophthalmology 1998 18 102-105.
6. Cannavo S, Venturino M, Curto L, De Menis E, D'Arrigo C, Tita P, Billeci D & Trimarchi F. Clinical presentation and outcome of pituitary adenomas in teenagers. Clinical Endocrinology 2003 58 519-527. (doi:10.1046/j.1365-2265. 2003.01748.x)
7. Pandey P, Ojha BK & Mahapatra AK. Pediatric pituitary adenoma: a series of 42 patients. Journal of Clinical Neuroscience 2005 12 124-127. (doi:10.1016/j.jocn.2004.10.003) (Pubitemid 40326653)
8. Tamura T, Tanaka R, Korii K & Okazaki H. Pediatric pituitary adenoma. Endocrine Journal 2000 47 S95-S99. (doi:10.1507/endocrj.47.SupplMarch-S95)
9. Colao A, Loche S, Cappa M, Di Sarno A, Landi ML, Sarnacchiaro F, Facciolli G & Lombardi G. Prolactinomas in children and adolescents. clinical presentation and long-term follow-up. Journal of Clinical Endocrinology and Metabolism 1998 83 2777-2780. (doi:10.1210/jc.83.8.2777)
10. Mindermann T & Wilson CB. Pediatric pituitary adenomas. Neurosurgery 1995 36 259-269. (doi:10.1227/00006123-199502000-00004)
11. Kunwar S & Wilson CB. Pediatric pituitary adenomas. Journal of Clinical Endocrinology and Metabolism 1999 84 4385-4389. (doi:10.1210/jc.84.12. 4385)
12. Mindermann T & Wilson CB. Age-related and gender-related occurrence of pituitary adenomas. Clinical Endocrinology 1994 41 359-364. (doi:10.1111/j.1365-2265.1994.tb02557.x)
13. Abe T, Ludecke DK & Saeger W. Clinically nonsecreting pituitary adenomas in childhood and adolescence. Neurosurgery 1998 42 744-750. (doi:10.1097/00006123-199804000-00037) (Pubitemid 28208358)
14. Dyer EH, Civit T, Visot A, Delalande O & Derome P. Transsphenoidal surgery for pituitary adenomas in children. Neurosurgery 1994 34 207-212. (doi:10.1227/00006123-199402000-00001)
15. Hirshfeld-Cytron J & Kim HH. Treatment of infertility in women with pituitary tumors. Expert Review of Anticancer Therapy 2006 6 (Supplement 9) S55-S62. (doi:10.1586/14737140.6.9s.S55)
16. Hall R, Manski-Nankervis J, Goni N, Davies MC & Conway GS. Fertility outcomes in women with hypopituitarism. Clinical Endocrinology 2006 65 71-74. (doi:10.1111/j.1365-2265.2006.02550.x)
17. Green DM, Kawashima T, Stovall M, Leisenring W, Sklar CA, Mertens AC, Donaldson SS, Byrne J & Robison LL. Fertility of female survivors of childhood cancer: a report from the childhood cancer survivor study. Journal of Clinical Oncology 2009 27 2677-2685. (doi:10.1200/JCO.2008.20.1541)
18. Tomlinson JW, Holden N, Hills RK, Wheatley K, Clayton RN, Bates AS, Sheppard MC & Stewart PM. Association between premature mortality and hypopituitarism. West Midlands prospective hypopituitary study group. Lancet 2001 357 425-431. (doi:10.1016/S0140-6736(00)04006-X)
19. Deepak D, Furlong NJ, Wilding JP & MacFarlane IA. Cardiovascular disease, hypertension, dyslipidaemia and obesity in patients with hypothalamic-pituitary disease. Postgraduate Medical Journal 2007 83 277-280. (doi:10.1136/pgmj.2006.052241) (Pubitemid 46663016)
20. Daousi C, Dunn AJ, Foy PM, MacFarlane IA & Pinkney JH. Endocrine and neuroanatomic features associated with weight gain and obesity in adult patients with hypothalamic damage. American Journal of Medicine 2005 118 45-50. (doi:10.1016/j.amjmed.2004.06.035)
21. Health Survey for England. Available from: http://www.dh.gov. uk/en/Publicationsandstatistics/Publications/PublicationsStatistics/DH-4098712, 2003.
22. Casanueva FF, Molitch ME, Schlechte JA, Abs R, Bonert V, Bronstein MD, Brue T, Cappabianca P, Colao A, Fahlbusch R, Fideleff H, Hadani M, Kelly P, Kleinberg D, Laws E, Marek J, Scanlon M, Sobrinho LG, Wass JA & Giustina A. Guidelines of the Pituitary Society for the diagnosis and management of prolactinomas. Clinical Endocrinology 2006 65 265-273. (doi:10.1111/j.1365-2265. 2006.02562.x)
23. Leinung MC, Kane LA, Scheithauer BW, Carpenter PC, Laws ER Jr & Zimmerman D. Long term follow-up of transsphenoidal surgery for the treatment of Cushing's disease in childhood. Journal of Clinical Endocrinology and Metabolism 1995 80 2475-2479. (doi:10.1210/jc.80.8.2475)
24. Linglart A & Visot A. Cushing's disease in children and adolescents. Neuro-Chirurgie 2002 48 271-280.
25. Magiakou MA, Mastorakos G, Oldfield EH, Gomez MT, Doppman JL, Cutler GB Jr, Nieman LK & Chrousos GP. Cushing's syndrome in children and adolescents. Presentation, diagnosis, and therapy. New England Journal of Medicine 1994 331 629-636. (doi:10.1056/NEJM199409083311002)
26. Massoud AF, Powell M, Williams RA, Hindmarsh PC & Brook CG. Transsphenoidal surgery for pituitary tumours. Archives of Disease in Childhood 1997 76 398-404. (doi:10.1136/adc.76.5.398)
27. Styne DM, Grumbach MM, Kaplan SL, Wilson CB & Conte FA. Treatment of Cushing's disease in childhood and adolescence by transsphenoidal microadenomectomy. New England Journal of Medicine 1984 310 889-893. (doi:10.1056/NEJM198404053101405)
28. Partington MD, Davis DH, Laws ER Jr & Scheithauer BW. Pituitary adenomas in childhood and adolescence. Results of transsphenoidal surgery. Journal of Neurosurgery 1994 80 209-216. (doi:10.3171/jns.1994.80.2.0209)
29. Greenman Y, Tordjman K & Stern N. Increased body weight associated with prolactin secreting pituitary adenomas: weight loss with normalization of prolactin levels. Clinical Endocrinology 1998 48 547-553. (doi:10.1046/j.1365- 2265.1998.00403.x) (Pubitemid 28252990)
30. Soran H, Wilding J & MacFarlane I. Body weight and prolactinoma: a retrospective study. International Journal of Obesity and Related Metabolic Disorders 2004 28 183. (doi:10.1038/sj.ijo.0802492)
31. McCrindle BW, Urbina EM, Dennison BA, Jacobson MS, Steinberger J, Rocchini AP, Hayman LL, Daniels SR & American Heart Association Atherosclerosis, Hypertension, and Obesity in Youth Committee, American Heart Association Council of Cardiovascular Disease in the Young & American Heart Association Council on Cardiovascular Nursing. Drug therapy of high-risk lipid abnormalities in children and adolescents: a scientific statement from the American Heart Association Atherosclerosis, Hypertension, and Obesity in Youth Committee, Council of Cardiovascular Disease in the Young, with the Council on Cardiovascular Nursing. Circulation 2007 115 1948-1967. (doi:10.1161/ CIRCULATIONAHA.107.181946)
32. Magnussen CG, Venn A, Thomson R, Juonala M, Srinivasan SR, Viikari JS, Berenson GS, Dwyer T & Raitakari OT. The association of pediatric low- and high-density lipoprotein cholesterol dyslipidemia classifications and change in dyslipidemia status with carotid intima-media thickness in adulthood evidence from the cardiovascular risk in young Finns study, the Bogalusa heart study, and the CDAH (childhood determinants of adult health) study. Journal of the American College of Cardiology 2009 53 860-869. (doi:10.1016/j.jacc.2008.09.061)
33. Adachi M, Muroya K & Asakura Y. Unfavorable lipoprotein profile in childhood cancer survivors with suprasellar brain tumors - a high apo B level and increased small dense LDL-cholesterol. Child's Nervous System 2009 25 669-675. (doi:10.1007/s00381-009-0837-3)
34. Daly AF, Tichomirowa MA & Beckers A. Update on familial pituitary tumors: from multiple endocrine neoplasia type 1 to familial isolated pituitary adenoma. Hormone Research 2009 71 (Supplement 1) 105-111. (doi:10.1159/ 000178050)
35. Leontiou CA, Gueorguiev M, van der Spuy J, Quinton R, Lolli F, Hassan S, Chahal HS, Igreja SC, Jordan S, Rowe J, Stolbrink M, Christian HC, Wray J, Bishop-Bailey D, Berney DM, Wass JA, Popovic V, Ribeiro-Oliveira AJr Jr, Gadelha MR, Monson JP, Akker SA, Davis JR, Clayton RN, Yoshimoto K, Iwata T, Matsuno A, Eguchi K, Musat M, Flanagan D, Peters G, Bolger GB, Chapple JP, Frohman LA, Grossman AB & Korbonits M. The role of the aryl hydrocarbon receptor-interacting protein gene in familial and sporadic pituitary adenomas. Journal of Clinical Endocrinology and Metabolism 2008 93 2390-2401. (doi:10.1210/jc.2007-2611)
36. Naves LA, Daly AF, Vanbellinghen JF, Casulari LA, Spilioti C, Magalhaes AV, Azevedo MF, Giacomini LA, Nascimento PP, Nunes RO, Rosa JW, Jaffrain-Rea ML, Bours V & Beckers A. Variable pathological and clinical features of a large Brazilian family harboring a mutation in the aryl hydrocarbon receptor-interacting protein gene. European Journal of Endocrinology 2007 157 383-391. (doi:10.1530/EJE-07-0533)
37. Vierimaa O, Georgitsi M, Lehtonen R, Vahteristo P, Kokko A, Raitila A, Tuppurainen K, Ebeling TM, Salmela PI, Paschke R, Gundogdu S, De Menis E, Makinen MJ, Launonen V, Karhu A & Aaltonen LA. Pituitary adenoma predisposition caused by germline mutations in the AIP gene. Science 2006 312 1228-1230. (doi:10.1126/science.1126100)
38. Toledo RA, Lourenco DM Jr, Liberman B, Cunha-Neto MB, Cavalcanti MG, Moyses CB, Toledo SP & Dahia PL. Germline mutation in the aryl hydrocarbon receptor interacting protein gene in familial somatotropinoma. Journal of Clinical Endocrinology and Metabolism 2007 92 1934-1937. (doi:10.1210/jc.2006- 2394) (Pubitemid 46997212)
39. Cazabat L, Libe R, Perlemoine K, Rene-Corail F, Burnichon N, Gimenez-Roqueplo AP, Dupasquier-Fediaevsky L, Bertagna X, Clauser E, Chanson P, Bertherat J & Raffin-Sanson ML. Germline inactivating mutations of the aryl hydrocarbon receptor-interacting protein gene in a large cohort of sporadic acromegaly: mutations are found in a subset of young patients with macroadenomas. European Journal of Endocrinology 2007 157 1-8. (doi:10.1530/EJE-07-0181)
40. Georgitsi M, De Menis E, Cannavò S, Mäkinen MJ, Tuppurainen K, Pauletto P, Curtò L, Weil RJ, Paschke R, Zielinski G, Wasik A, Lubinski J, Vahteristo P, Karhu A & Aaltonen LA. Aryl hydrocarbon receptor interacting protein (AIP) gene mutation analysis in children and adolescents with sporadic pituitary adenomas. Clinical Endocrinology 2008 69 621-627. (doi:10.1111/j.1365-2265.2008.03266.x)
41. Daly AF, Tichomirowa MA & Beckers A. The epidemiology and genetics of pituitary adenomas. Best Practice and Research. Clinical Endocrinology and Metabolism 2009 23 543-554. (doi:10.1016/j.beem.2009.05.008)