Discontinuation of standard first-line antiretroviral therapy in a cohort of 1434 Malawian children

Journal of the International AIDS Society

Volumn 13, Issue 1, 2010, Pages

  Buck, W Chris ^a   Kabue, Mark M ^b   Kazembe, Peter N ^b   Kline, Mark W ^c  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b Baylor University   (United States)

^c TEXAS CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LAMIVUDINE PLUS NEVIRAPINE PLUS STAVUDINE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; LAMIVUDINE; NEVIRAPINE; STAVUDINE;

ADOLESCENT; ADULT; ARTICLE; CHILD; COHORT ANALYSIS; DRUG DOSE REGIMEN; DRUG WITHDRAWAL; FEMALE; FOLLOW UP; GROUPS BY AGE; HEPATITIS; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; IMMUNE RESPONSE; INFECTION PREVENTION; LACTIC ACIDOSIS; MAJOR CLINICAL STUDY; MALAWI; MALE; OUTCOME ASSESSMENT; PANCREATITIS; PEDIATRICS; PERIPHERAL NEUROPATHY; PRESCHOOL CHILD; PRIORITY JOURNAL; RASH; RETROSPECTIVE STUDY; SCHOOL CHILD; STEVENS JOHNSON SYNDROME; TREATMENT FAILURE; TREATMENT INDICATION; DRUG COMBINATION; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFANT;

ADOLESCENT; ANTI-HIV AGENTS; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; DRUG THERAPY, COMBINATION; FEMALE; FOLLOW-UP STUDIES; HIV INFECTIONS; HUMANS; INFANT; LAMIVUDINE; MALAWI; MALE; NEVIRAPINE; STAVUDINE; YOUNG ADULT;

EID: 77957135518     PISSN: None     EISSN: 17582652     Source Type: Journal    
DOI: 10.1186/1758-2652-13-31     Document Type: Article

References (9)

1. Pharmacokinetics of nevirapine in HIV-infected children receiving an adult fixed-dose combination of stavudine, lamivudine and nevirapine. K Chokephaibulkit N Plipat TR Cressey K Frederix W Phongsamart E Capparelli T Kolladarungkri N Vanprapar, AIDS 2005 19 1495 1499 10.1097/01.aids.0000183625. 97170.59 16135903
2. Nevirapine concentrations in HIV-infected children treated with divided fixed-dose combination antiretroviral tablets in Malawi and Zambia. J Ellis R L'homme F Ewings V Mulenga F Bell R Chileshe E Molyneux J Abernathy J van Oosterhout C Chintu S Walker D Gibb D Burger, Antiviral Therapy 2007 12 253 260 17503667
3. Nevirapine vs. lopinavir-ritonavir-based antiretroviral therapy (ART) in single dose nevirapine (sdNVP)-exposed HIV infected infants: preliminary results from the IMPAACT P1060 trial. P Palumbo A Violari J Lindsey M Hughes P Jean-Philippe L Mofenson L Purdue S Eshleman, HIV Pediatrics Cape Town, abstract LBPEB12, July 2009
4. World Health Organization, Rapid advice: antiretroviral therapy for HIV infection in adults and adolescents. Electronic version 2009 http://www.who.int/hiv/pub/arv/rapid-advice-art.pdf
5. Insights into the reasons for discontinuation of the first highly active antiretroviral therapy (HAART) regimen in a cohort of antiretroviral nave patients. I.CO.N.A. Study Group. Italian Cohort of Antiretroviral-Nave Patients. A d'Arminio Monforte AC Lepri G Rezza P Pezzotti A Antinori AN Phillips G Angarano V Colangeli A De Luca G Ippolito L Caggese F Soscia G Filice F Gritti P Narciso U Tirelli M Moroni, AIDS 2000 14 Suppl 5 499 507 10.1097/00002030- 200003310-00005 10780712
6. Hepatotoxicity in HIV-infected children and adolescents on antiretroviral therapy. AC Gil R Lorenzetti GB Mendes AM Morcillo AA Toro MT Silva MM Vilela, Sao Paulo Med J 2007 125 205 209 10.1590/S1516-31802007000400002 17992389
7. Metabolic complications of HIV therapy in children. G McComsey E Leonard, AIDS 2004 18 1753 1768 10.1097/00002030-200409030-00004 15316336
8. Malawi Ministry of Health, HIV Unit, Treatment of AIDS. A Five-Year Plan for the Provision of Antiretroviral Therapy and Good Management of HIV-related Diseases to HIV-infected Patients in Malawi 2006-2010 http://www.hivunitmohmw. org/uploads/Main/ARV-ScaleUpPlan-2006-2010.pdf
9. Routine versus clinically driven laboratory monitoring of HIV antiretroviral therapy in Africa (DART): a randomised non-inferiority trial. Dart Trial Team, Lancet 2010 375 123 131 10.1016/S0140-6736(09)62067-5 20004464