Proton magnetic resonance spectroscopy of brain in obstructive sleep apnoea in north Indian Asian subjects

Indian Journal of Medical Research

Volumn 132, Issue 9, 2010, Pages 278-286

  Sharma, Surendra K ^a   Sinha, S ^a   Danishad, K A ^a   Sharma, U ^a   Sharma, H ^a   Mishra, H K ^a   Mishra, H ^a   Kadhiravan, T ^a   Reddy, V V ^a   Sreenivas, V ^a   Jagannathan, N R ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Brain metabolites; Glutamate + glutamine (Glx); Magnetic resonance spectroscopy (MRS); Myo inositol (mI); N acetyl aspartate (NAA)Obstructive sleep apnoea (OSA); North indian subjects

Indexed keywords

CHOLINE; CREATINE PHOSPHATE; GLUTAMIC ACID; GLUTAMINE; GYLCEROPHOSPHOCHOLINE; INOSITOL; N ACETYLASPARTIC ACID; N ACETYLASPARTYLGLUTAMIC ACID; PHOSPHORYLCHOLINE; UNCLASSIFIED DRUG; ASPARTIC ACID; DIPEPTIDE; DRUG DERIVATIVE; N ACETYL 1 ASPARTYLGLUTAMIC ACID; N-ACETYL-1-ASPARTYLGLUTAMIC ACID; N-ACETYLASPARTATE;

ADULT; APNEA HYPOPNEA INDEX; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FRONTAL LOBE; HUMAN; INDIAN; MALE; OCCIPITAL LOBE; POLYSOMNOGRAPHY; PROTON NUCLEAR MAGNETIC RESONANCE; SLEEP APNEA SYNDROME; TEMPORAL LOBE; ANALYSIS OF VARIANCE; ANTHROPOMETRY; BRAIN; COMPARATIVE STUDY; INDIA; METABOLISM; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

ADULT; ANALYSIS OF VARIANCE; ANTHROPOMETRY; ASPARTIC ACID; BRAIN; DIPEPTIDES; FEMALE; HUMANS; INDIA; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MIDDLE AGED; POLYSOMNOGRAPHY; SLEEP APNEA, OBSTRUCTIVE;

EID: 77957100917     PISSN: 09715916     EISSN: 09715916     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Sharma SK. Wake-up call for sleep disorders in developing nations! Indian J Med Res 2010; 131: 115.
2. Lam Jamie CM, Sharma SK, Lam Bing. Obstructive sleep apnea: Definitions, epidemiology & natural history. Indian J Med Res 2010; 131: 165-70.
3. Sharma SK, Ahluwalia G. Epidemiology of adult obstructive sleep apnea syndrome in India. Indian J Med Res 2010; 131: 171-5.
4. Gurubhagavatula. Consequences of obstructive sleep apnoea. Indian J Med Res 2010; 131: 188-95.
5. Bruhn H, Frahm J, Gyngell ML, Merboldt KD, Hänicke W, Sauter R. Cerebral metabolism in man after acute stroke: new observations using localized proton NMR spectroscopy. Magn Reson Med 1989; 9: 126-31.
6. Kales A, Caldwell AB, Cadieux RJ, Vela-Bueno A, Ruch LG, Mayes SD. Severe obstructive sleep apnea-II: associated psychopathology and psychosocial consequences. J Chronic Dis 1985; 38: 427-34.
7. Findley LJ, Barth JT, Powers DC, Wilhoit SC, Boyd DG, Suratt PM. Cognitive impairment in patients with obstructive sleep apnea and associated hypoxemia. Chest 1986; 90: 686-90.
8. Greenberg GD, Watson RK, Deptula D. Neuropsychological dysfunction in sleep apnea. Sleep 1987; 10: 254-62.
9. Montplaisir J, Bédard MA, Richer F, Rouleau I. Neurobehavioral manifestations in obstructive sleep apnea syndrome before and after treatment with continuous positive airway pressure. Sleep 1992; 15 (Suppl 6): S17-9.
10. Carskadon MA, Dement WC, Mitler MM, Roth T, Westbrook PR, Keenan S. Guidelines for the multiple sleep latency test (MSLT): a standard measure of sleepiness. Sleep 1986; 9: 519-24.
11. Poceta JS, Timms RM, Jeong DU, Ho SL, Erman MK, Mitler MM. Maintenance of wakefulness test in obstructive sleep apnea syndrome. Chest 1992; 101: 893-7.
12. Macey PM, Henderson LA, Macey KE, Alger JR, Frysinger RC, Woo MA, et al. Brain morphology associated with obstructive sleep apnea. Am J Respir Crit Care Med 2002; 166: 1382-7.
13. Morrell MJ, McRobbie DW, Quest RA, Cummin AR, Ghiassi R, Corfield DR. Changes in brain morphology associated with obstructive sleep apnea. Sleep Med 2003; 4: 451-4.
14. Gale SD, Hopkins RO. Effects of hypoxia on the brain: neuroimaging and neuropsychological findings following carbon monoxide poisoning and obstructive sleep apnea. J Int Neuropsychol Soc 2004; 10: 60-71.
15. O'Donoghue FJ, Briellmann RS, Rochford PD, Abbott DF, Pell GS, Chan CH, et al. Cerebral structural changes in severe obstructive sleep apnea. Am J Respir Crit Care Med 2005; 171: 1185-90.
16. Kamba M, Suto Y, Ohta Y, Inoue Y, Matsuda E. Cerebral metabolism in sleep apnea. evaluation by magnetic resonance spectroscopy. Am J Respir Crit Care Med 1997; 156: 296-8.
17. Kamba M, Inoue Y, Higami S, Suto Y, Ogawa T, Chen W. Cerebral metabolic impairment in patients with obstructive sleep apnoea: an independent association of obstructive sleep apnoea with white matter change. J Neurol Neurosurg Psychiatry 2001; 71: 334-9.
18. Alchanatis M, Deligiorgis N, Zias N, Amfilochiou A, Gotsis E, Karakatsani A, et al. Frontal brain lobe impairment in obstructive sleep apnoea: a proton MR spectroscopy study. Eur Respir J 2004; 24: 980-6.
19. Bartlett DJ, Rae C, Thompson CH, Byth K, Joffe DA, Enright T, et al. Hippocampal area metabolites relate to severity and cognitive function in obstructive sleep apnea. Sleep Med 2004; 5: 593-6.
20. Tonon C, Vetrugno R, Lodi R, Gallassi R, Provini F, Iotti S, et al. Proton magnetic resonance spectroscopy study of brain metabolism in obstructive sleep apnoea syndrome before and after continuous positive airway pressure treatment. Sleep 2007; 30: 305-11.
21. Sarchielli P, Presciutti O, Alberti A, Tarducci R, Gobbi G, Galletti F, et al. A 1H magnetic resonance spectroscopy study in patients with obstructive sleep apnea. Eur J Neurol 2008; 15: 1058-64.
22. Zimmerman ME, Aloia MS. A review of neuroimaging in obstructive sleep apnea. J Clin Sleep Med 2006; 2: 461-71.
23. Halbower AC, Degaonkar M, Barker PB, Earley CJ, Marcus CL, Smith PL, et al. Childhood obstructive sleep apnea associates with neuropsychological deficits and neuronal brain injury. PloS Med 2006; 3: e301.
24. Davies RJ, Stradling JR. The relationship between neck circumference, radiographic pharyngeal anatomy and the obstructive sleep apnoea syndrome. Eur Resp J 1990; 3: 509-14.
25. Sharma SK, Kumpawat S, Banga A, Goel A. Prevalence and risk factors of obstructive sleep apnea syndrome in a population of Delhi, India. Chest 2006; 130: 149-56.
26. Birken DL, Oldendorf WH. N-acetyl-L-aspartic acid: a literature review of a compound prominent in 1H NMR spectroscopic studies of brain. Neurosci Biobehav Rev 1989; 13: 23-31.
27. Neale JH, Bzdega T, Wroblewska B. N-Acetylaspartylglutamate: the most abundant peptide neurotransmitter in the mammalian central nervous system. J Neurochem 2000; 75: 443-52.
28. Sánchez-Olea R, Peña C, Morán J, Pasantes-Morales H. Inhibition of volume regulation and efflux of osmoregulatory amino acids by blockers of Cl- transport in cultured astrocytes. Neurosci Lett 1993; 156: 141-4.
29. Tsai GC, Passani LA, Slusher BS, Carter R, Baer L, Kleinman JE, et al. Abnormal excitatory neurotransmitter metabolism in schizophrenic brains. Arch Gen Psychiatry 1995; 52: 829-36.
30. Tsai GC, Stauch-Slusher B, Sim L, Hedreen JC, Rothstein JD, Kuncl R, et al. Reductions in acidic amino acids and N-acetylaspartylglutamate in amyotrophic lateral sclerosis CNS. Brain Res 1991; 556: 151-6.
31. Ross BD. Biochemical considerations in 1H spectroscopy. Glutamate and glutamine: myo-inositol and related metabolites. NMR Biomed 1991; 4: 59-63.
32. Brzecka A. Role of hypercapnia in brain oxygenation in sleep-disordered breathing. Acta Neurobiol Exp (Wars) 2007; 67: 197-206.