UPLC-Q-TOF-MS analysis of naringin and naringenin and its metabolites in rat plasma after intragastrical administration of alcohol extract of exocarpium Citri grandis

Zhongguo Zhongyao Zazhi

Volumn 35, Issue 12, 2010, Pages 1580-1585

  Sun, Guoling ^a   Qian, Dawei ^b   Duan, Jin'ao ^b   Li, Xiangming ^c   Wan, Jianyi ^c   Guo, Jianming ^b  

^a JIANGSU UNIVERSITY   (China)

^b NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^c Huazhou Green Life CoLtd   (China)

Author keywords

Citri grandis; Metabolites; Naringenin; Naringin; UPLC Q TOF MS

Indexed keywords

AURANTIIN; CITRI GRANDIS EXTRACT; DRUG METABOLITE; NARINGENIN; NARINGIN 4 O GLUCURONIDE; NARINGIN 4 O SULFATE; NARINGIN 5 O GLUCURONIDE; PLANT EXTRACT; UNCLASSIFIED DRUG; FLAVANONE DERIVATIVE;

ARTICLE; BLOOD SAMPLING; CITRI GRANDIS; GLUCURONIDATION; HYDROXYLATION; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; METABOLITE; METHYLATION; NONHUMAN; PLANT; PLASMA; RAT; SULFATION; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ANIMAL; BLOOD; CHEMISTRY; CITRUS; DRUG ADMINISTRATION ROUTE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; METABOLISM; RANDOMIZATION; SPRAGUE DAWLEY RAT;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CITRUS; DRUG ADMINISTRATION ROUTES; FLAVANONES; MALE; MASS SPECTROMETRY; PLANT EXTRACTS; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY;

EID: 77957100556     PISSN: 10015302     EISSN: None     Source Type: Journal    
DOI: 10.4268/cjcmm20101217     Document Type: Article

References (8)

1. Junmei Zhang, Jennifer S Brodbelt. Screening flavonoid metabolites of naringin and narirutin in urine after human consumption of grapefruit juice by LC-MS and LC-MS/MS[J]. Analyst, 2004,129:1227.