Primary pulmonary biphasic synovial sarcoma confirmed by molecular detection of a SYT SSX2 fusion gene: Report of 1 case

Korean Journal of Internal Medicine

Volumn 25, Issue 3, 2010, Pages 331-336

  Park, Jae Seok ^a   Min, Bo Ram ^a   Park, Soon Hyo ^a   Kwon, Kun Young ^a   Keum, Dong Yoon ^a   Choi, Won II ^a  

^a Dongsan Medical Center   (South Korea)

Author keywords

Gene fusion; Lung neoplasms; Sarcoma; Synovial

Indexed keywords

BETA CATENIN; CD99 ANTIGEN; FLUORODEOXYGLUCOSE F 18; HYBRID PROTEIN; PROTEIN BCL 2; PROTEIN S 100; RNA; SYT SSX2 FUSION PROTEIN; UNCLASSIFIED DRUG; ONCOPROTEIN; PRIMER DNA; SYT-SSX FUSION PROTEIN;

ADULT; ARTICLE; CANCER TISSUE; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; FROZEN SECTION; GENE AMPLIFICATION; GENETIC ANALYSIS; GENOME SIZE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; LUNG BIOPSY; LUNG LOBECTOMY; LUNG SARCOMA; LYMPH NODE DISSECTION; MALE; POSITRON EMISSION TOMOGRAPHY; PULMONARY BIPHASIC SYNOVIAL SARCOMA; RECURRENT CANCER; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; THORAX RADIOGRAPHY; GENETICS; KOREA; LUNG NEOPLASMS; MIDDLE AGED; NUCLEOTIDE SEQUENCE; ONCOGENE; SARCOMA, SYNOVIAL;

BASE SEQUENCE; DNA PRIMERS; HUMANS; KOREA; LUNG NEOPLASMS; MALE; MIDDLE AGED; ONCOGENE PROTEINS, FUSION; ONCOGENES; SARCOMA, SYNOVIAL;

EID: 77957040131     PISSN: 12263303     EISSN: 20056648     Source Type: Journal    
DOI: 10.3904/kjim.2010.25.3.331     Document Type: Article

References (12)

1. Hosono T, Hironaka M, Kobayashi A, et al. Primary pulmonary synovial sarcoma confirmed by molecular detection of SYT-SSX1 fusion gene transcripts: a case report and review of the literature. Jpn J Clin Oncol 2005;35:274-279.
2. Kawai A, Woodruff J, Healey JH, Brennan MF, Antonescu CR, Ladanyi M. SYT-SSX gene fusion as a determinant of morphology and prognosis in synovial sarcoma. N Engl J Med 1998;338:153-160.
3. Coindre JM, Pelmus M, Hostein I, Lussan C, Bui BN, Guillou L. Should molecular testing be required for diagnosing synovial sarcoma? A prospective study of 204 cases. Cancer 2003;98: 2700-2707.
4. Begueret H, Galateau-Salle F, Guillou L, et al. Primary intrathoracic synovial sarcoma: a clinicopathologic study of 40 t(X;18)-positive cases from the French Sarcoma Group and the Mesopath Group. Am J Surg Pathol 2005;29:339-346.
5. Ladanyi M, Antonescu CR, Leung DH, et al. Impact of SYT-SSX fusion type on the clinical behavior of synovial sarcoma: a multiinstitutional retrospective study of 243 patients. Cancer Res 2002;62:135-140.
6. Guillou L, Benhattar J, Bonichon F, et al. Histologic grade, but not SYT-SSX fusion type, is an important prognostic factor in patients with synovial sarcoma: a multicenter, retrospective analysis. J Clin Oncol 2004;22:4040-4050.
7. Lee EA, Lee DY, Kwag HJ, et al. A case of monophasic fibrous synovial sarcoma confirmed primary pulmonary origin by 18FFDG PET/CT. Tuberc Respir Dis 2006;60:673-677.
8. Shin SH, Song DS, Jung WS, et al. Primary pulmonary synovial sarcoma with brain metastasis. Korean J Thorac Cardiovasc Surg 2000;33:329-332.
9. Song SH, Lee KH, Oh JH, et al. A case of primary pulmonary sarcoma with morphologic features of biphasic synovial sarcoma. Tuberc Respir Dis 1998;45:1284-1289.
10. Yoon GS, Park SY, Kang GH, Kim OJ. Primary pulmonary sarcoma with morphologic features of biphasic synovial sarcoma: a case report. J Korean Med Sci 1998;13:71-76.
11. Kim MH, Kim KT, Kim HJ. Primary pulmonary synovial sarcoma: a case report. Korean J Thorac Cardiovasc Surg 1997;30:1259-1261.
12. Shin JS, Hwang JJ, Choi YH, Kim HJ. Intrapulmonary synovial sarcoma: a case report. Korean J Thorac Cardiovasc Surg 1993;26:726-729.