T-cell regulation by casitas B-lineage lymphoma (Cblb) is a critical failsafe against autoimmune disease due to autoimmune regulator (Aire) deficiency

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 33, 2010, Pages 14709-14714

  Teh, Charis E ^a   Daley, Stephen R ^a   Enders, Anselm ^a   Goodnow, Christopher C ^a  

^a Australian National University   (Australia)

Author keywords

Anergy; Autoimmunity; Pancreatitis; Tolerance; Ubiquitin ligase

Indexed keywords

AUTOIMMUNE REGULATOR PROTEIN; CD28 ANTIGEN; FAS LIGAND; TRANSCRIPTION FACTOR FOXP3; CBL PROTEIN; CBLB PROTEIN, MOUSE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TRANSCRIPTION FACTOR;

ACINAR CELL; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNE PANCREATITIS; AUTOIMMUNE REGULATOR PROTEIN DEFICIENCY; AUTOIMMUNITY; B CELL LYMPHOMA; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL DEATH; CELL LINEAGE; COMPETITIVE INHIBITION; CONTROLLED STUDY; EMBRYO; EXOCRINE CELL; FEMALE; GENETIC DISORDER; HAPLOTYPE; IMMUNOLOGICAL TOLERANCE; IMMUNOREGULATION; LYMPHOCYTE SUBPOPULATION; LYMPHOCYTIC INFILTRATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; REGULATORY T LYMPHOCYTE; SUBMANDIBULAR GLAND; T LYMPHOCYTE; ADOPTIVE TRANSFER; ANIMAL; AUTOIMMUNE POLYENDOCRINOPATHY; BONE MARROW CELL; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; GENOTYPE; HISTOCOMPATIBILITY; HUMAN; IMMUNOLOGY; METABOLISM; MOUSE MUTANT; MOUSE STRAIN; PANCREAS; PATHOLOGY; SALIVARY GLAND; STOMACH;

MUS;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADOPTIVE TRANSFER; ANIMALS; BONE MARROW CELLS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; FEMALE; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENOTYPE; HUMANS; MALE; MICE; MICE, INBRED STRAINS; MICE, KNOCKOUT; PANCREAS; POLYENDOCRINOPATHIES, AUTOIMMUNE; PROTO-ONCOGENE PROTEINS C-CBL; SALIVARY GLANDS; STOMACH; T-LYMPHOCYTES, REGULATORY; TRANSCRIPTION FACTORS; TRANSPLANTATION CHIMERA;

EID: 77957036387     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1009209107     Document Type: Article

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