Analysis of distribution of oxygen transfer rate in stirred bioreactors for yeasts broths

Romanian Biotechnological Letters

Volumn 15, Issue 4, 2010, Pages 5423-5435

  Galaction, Anca Irina ^a   Caşcaval, Dan ^b   Cǎmǎruţ, Ştefǎnica ^b  

^a GRIGORE T POPA UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^b GHEORGHE ASACHI TECHNICAL UNIVERSITY OF IASI   (Romania)

Author keywords

Kla; Mass transfer; Mass transfer coefficient; Saccharomyces cerevisiae; Specific power input; Stirred bioreactor; Superficial air velocity

Indexed keywords

BACTERIA (MICROORGANISMS); SACCHAROMYCES CEREVISIAE;

EID: 77957002503     PISSN: 12245984     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. AIBA S., HUMPHREY A.E., MILLIS N.F. Biochemical Engineering, Academic Press, New York, 1973, pp. 183.
2. MOO-YOUNG M., COONEY CH.L., HUMPHREY A.E. (Eds.). Comprehensive Biotechnology, vol. 2, Pergamon Press, Oxford, 1985, pp. 16.
3. HO C.S., OLSHUE J.Y. (Eds.). Biotechnology Processes Scale-up and Mixing, American Institute of Chemical Engineering, 1987, pp. 128.
4. VAN'T RIET K., TRAMPER J. Basic Bioreactor Design, M. Dekker Inc., New York, 1991, pp. 236.
5. GALACTION A.I., CASCAVAL D., ONISCU C., TURNEA M. Prediction of oxygen transfer coefficients in stirred bioreactors for bacteria, yeasts and fungus broths, Biochem. Eng. J., 20, 85-94 (2004).
6. PUTHLI M.S., RATHOD V.K., PANDIT A.B. Optimization of lipase production in a triple impeller bioreactor, Biochem. Eng. J., 27, 287-294 (2006).
7. VAN'T RIET K. Review of measuring methods and results in nonviscous gas-liquid mass transfer in stirred vessels, Ind. Chem. Proc. Des. Dev., 18, 357-362 (1979).
8. La in yeasts broths, Proc. Biochem., 34, 549-554 (1999).
9. BAKKER A., VAN DEN AKKER H.E.A., Gas-liquid contacting with axial flow impellers. Chemical engineering research and design, Trans. I.Chem.E., 72 (Part A), 594-606 (1994).
10. HJERTAGER B.H. Computational fluid dynamics (CFD) analysis of multiphase chemical reactor, Trends Chem. Eng., 4, 45-91 (1998).
11. LANE G.L., SCHWARZ M.P., EVANS G.M. Predicting gas-liquid flow in a mechanically stirred tank, Appl. Mathem. Model., 26, 223-235 (2002).
12. BUJALSKI J.M, Ph.D. Thesis, University of Birmingham, 2003, p. 22.
13. LANE G.L., SCHWARZ M.P., Evans G.M. Numerical modelling of gas-liquid flow in stirred tanks, Chem. Eng. Sci., 60, 2203-2214 (2005).
14. KERDOUSS F., BANNARI A., PROULX P. CFD modeling of gas dispersion and bubble size in a double turbine stirred tank, Chem. Eng. Sci., 61, 3313-3322 (2006).
15. KERDOUSS, F., BANNARI, A., PROULX, P., BANNARI, R., SKRGA, M., LABRECQUE Y. Two-phase mass transfer coefficients prediction in a bioreactor with a CFD model, Computer Chem. Eng., 32, 1943-1955 (2008).
16. ONISCU C., GALACTION A.I., CASCAVAL D., UNGUREANU F. Modeling of mixing in stirred bioreactors. 2. Mixing time for non-aerated fermentation broths, Biochem. Eng. J., 12, 61-65 (2002).
17. GALACTION A.I., CASCAVAL D., ONISCU C., TURNEA M. Evaluation and modeling of the aerobic stirred bioreactor performances for fungus broths, Chem. Biochem. Eng. Quart., 19, 87-97 (2005).
18. GALACTION A.I., CǍMǍRUT S., CAŞCAVAL D., TUDOSE R. Evaluation and modeling of the aerobic stirred bioreactor performances for fungus broths, Environ. Eng. Manag. J., 7, 199-211 (2008).
19. CASCAVAL D., GALACTION A.I., TURNEA M. Comparative analysis of mixing distribution in aerobic stirred bioreactor for simulated, yeasts and fungus broths, J. Ind. Microbiol. Biotechnol., 34, 35-47 (2007).
20. CAŞCAVAL D., GALACTION A.I., CǍMǍRUT S. Analysis of distribution of oxygen transfer rate in stirred bioreactors for bacterial broths, Environ. Eng. Manag. J., 8, 17-27 (2009).
21. GALACTION A.I., CAŞCAVAL D., CǍMǍRUT S., TURNEA M. Evaluation of the hydrodynamic regime of aerobic stirred bioreactors using the mixing distribution criteria. 2. Saccharomyces cerevisiae broths, Roum. Biotechnol. Lett., 11, 2739-2748 (2006).
22. MIYACHI M., IGUCHI A., UCHIDA S., KOIDE K. Effect of solid particles in liquid-phase on liquid-side mass transfer coefficient, Can. J. Chem. Eng., 59, 640-645 (1981).
23. OZBEK B., GAYIK S. The studies on the oxygen mass transfer coefficient in a bioreactor, Proc. Biochem., 36, 729-741 (2001).
24. WEBER M.E., PADDOCK D. Interceptional and gravitational collision efficiencies for single collectors at intermediate Reynolds numbers, J. Colloid. Interface Sci., 94, 328-335 (1983).
25. JU L.K., SUNDARARAJAN A. The effects of cells on oxygen. transfer in bioreactors: Physical presence of cells as solid particles, Chem. Eng. J., 56, B 15-22 (1994).
26. CHISTI Y., JAUREGUI-HAZA U.J. Oxygen transfer and mixing in mechanically agitated airlift bioreactors, Biochem. Eng. J., 10, 143-153 (2002).