Orthopaedic sequelae of childhood meningococcemia: Management considerations and outcome

Journal of Bone and Joint Surgery

Volumn 92, Issue 12, 2010, Pages 2196-2203

  Canavese, Federico ^a   Krajbich, Joseph I ^a   LaFleur, Brett J ^a  

^a SHRINERS HOSPITAL FOR CHILDREN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; AMPUTATION; ARM AMPUTATION; ARM MALFORMATION; ARTICLE; BACTERIAL OVERGROWTH; BONE INFECTION; CHILD; CLINICAL ARTICLE; FEMALE; FOLLOW UP; FULMINATING PURPURA; GROWTH DISORDER; HUMAN; INFANT; LEG AMPUTATION; LEG MALFORMATION; MALE; MENINGOCOCCEMIA; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; SEPSIS; SOFT TISSUE INFECTION; TREATMENT OUTCOME; MENINGOCOCCOSIS; MUSCULOSKELETAL DISEASE; RETROSPECTIVE STUDY; TIME;

ADOLESCENT; ADULT; AMPUTATION; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; INFANT; MALE; MENINGOCOCCAL INFECTIONS; MUSCULOSKELETAL DISEASES; PURPURA FULMINANS; RETROSPECTIVE STUDIES; SEPSIS; TIME FACTORS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 77956989904     PISSN: 00219355     EISSN: 15351386     Source Type: Journal    
DOI: 10.2106/JBJS.I.01468     Document Type: Article

References (25)

1. Milonovich LM. Meningococcemia: epidemiology, pathophysiology, and management. J Pediatr Health Care. 2007;21:75-80.
2. Leclerc F, Leteurtre S, Cremer R, Fourier C, Sadik A. Do new strategies in meningococcemia produce better outcomes? Crit Care Med. 2000;28(9 Suppl):S60-3.
3. Genoff MC, Hoffer MM, Achauer B, Formosa P. Extremity amputations in meningococcemia-induced purpura fulminans. Plast Reconstr Surg. 1992;89:878-81.
4. Davies MS, Nadel S, Habibi P, Levin M, Hunt DM. The orthopaedic management of peripheral ischaemia in meningococcal septicaemia in children. J Bone Joint Surg Br. 2000;82:383-6.
5. Bache CE, Torode IP. Orthopaedic sequelae of meningococcal septicemia. J Pediatr Orthop. 2006;26:135-9.
6. Nogi J. Physeal arrest in purpura fulminans. A report of three cases. J Bone Joint Surg Am. 1989;71:929-31.
7. Grogan DP, Love SM, Ogden JA, Millar EA, Johnson LO. Chondro-osseous growth abnormalities after meningococcemia. A clinical and histopathological study. J Bone Joint Surg Am. 1989;71:920-8.
8. Barre PS, Thompson GH, Morrison SC. Late skeletal deformities following meningococcal sepsis and disseminated intravascular coagulation. J Pediatr Orthop. 1985;5:584-8.
9. Jacobsen ST, Crawford AH. Amputation following meningococcemia. A sequela to purpura fulminans. Clin Orthop Relat Res. 1984;185:214-9.
10. Patriquin HB, Trias A, Jecquier S, Marton D. Late sequelae of infantile meningococcemia in growing bones of children. Radiology. 1981;141:77-82.
11. Santos E, Boavida JE, Barroso A, Seabra J, Carmona da Mota H. Late osteoarticular lesions following meningococcemia with disseminated intravascular coagulation. Pediatr Radiol. 1989;19:199-202.
12. Palisano R, Rosenbaum P, Walter S, Russell D, Wood E, Galuppi B. Development and reliability of a system to classify gross motor function in children with cerebral palsy. Dev Med Child Neurol. 1997;39:214-23.
13. Fernández F, Pueyo I, Jiménez JR, Vigil E, Guzmán A. Epiphysiometaphyseal changes in children after severe meningococcic sepsis. AJR Am J Roentgenol. 1981;136:1236-8.
14. Robinow M, Johnson GF, Nanagas MT, Mesghali H. Skeletal lesions following meningococcemia and disseminated intravascular coagulation. A recognizable skeletal dystrophy. Am J Dis Child. 1983;137:279-81.
15. Jaramillo D, Shapiro F, Hoffer FA, Winalski CA, Koskinen MF, Frasso R, Johnson A. Posttraumatic growth-plate abnormalities: MR imaging of bony-bridge formation in rabbits. Radiology. 1990;175:767-73.
16. Jaramillo D, Laor T, Zaleske DJ. Indirect trauma to the growth plate: results of MR imaging after epiphyseal and metaphyseal injury in rabbits. Radiology. 1993;187:171-8.
17. Ecklund K, Jaramillo D. Patterns of premature physeal arrest: MR imaging of 111 children. AJR Am J Roentgenol. 2002;178:967-72.
18. Lohman M, Kivisaari A, Vehmas T, Kallio P, Puntila J, Kivisaari L. MRI in the assessment of growth arrest. Pediatr Radiol. 2002;32:41-5.
19. Hamdy RC, Babyn PS, Krajbich JI. Use of bone scan in management of patients with peripheral gangrene due to fulminant meningococcemia. J Pediatr Orthop. 1993;13:447-51.
20. Silbart S, Oppenheim W. Purpura fulminans. Medical, surgical, and rehabilitative considerations. Clin Orthop Relat Res. 1985;193:206-13.
21. Farrar MJ, Bennet GC, Wilson NI, Azmy A. The orthopaedic implications of peripheral limb ischaemia in infants and children. J Bone Joint Surg Br. 1996;78:930-3.
22. Hudson DA, Goddard EA, Millar KN. The management of skin infarction after meningococcal septicaemia in children. Br J Plast Surg. 1993;46:243-6.
23. Toews WH, Bass JW. Skin manifestations of meningococcal infection; an immediate indicator of prognosis. Am J Dis Child. 1974;127:173-6.
24. Canavese F, Krajbich JI, Kuang AA. Application of the vacuum-assisted closure in pediatric patients with orthopedic sequelae of meningococcemia: report of a case successfully treated. J Pediatr Orthop B. 2009 Jul 17 [Epub ahead of print].
25. Fellick JM, Sills JA, Marzouk O, Hart CA, Cooke RW, Thomson AP. Neurodevelopmental outcome in meningococcal disease: a case-control study. Arch Dis Child. 2001;85:6-11.