Hypoxia enhances the angiogenic potential of human dental pulp cells

Journal of Endodontics

Volumn 36, Issue 10, 2010, Pages 1633-1637

  Aranha, Andreza M F ^a,b   Zhang, Zhaocheng ^a   Neiva, Kathleen G ^a   Costa, Carlos A S ^b   Hebling, Josimeri ^b   Nör, Jacques E ^a,c,d  

^a UNIVERSITY OF MICHIGAN   (United States)

^b SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^d The Department of Civil and Environmental Engineering   (United States)

Author keywords

Angiogenesis; dental pulp; endodontics; tissue regeneration; trauma

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; VASCULOTROPIN A;

ADULT STEM CELL; ANGIOGENESIS; ARTICLE; BIOSYNTHESIS; CELL CULTURE; CELL HYPOXIA; CYTOLOGY; DRUG ANTAGONISM; FIBROBLAST; HUMAN; METABOLISM; NONPARAMETRIC TEST; PHYSIOLOGY; REGENERATION; SIGNAL TRANSDUCTION; TOOTH PULP; VASCULAR ENDOTHELIUM;

ADULT STEM CELLS; CELL HYPOXIA; CELLS, CULTURED; DENTAL PULP; ENDOTHELIUM, VASCULAR; FIBROBLASTS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; NEOVASCULARIZATION, PHYSIOLOGIC; REGENERATION; SIGNAL TRANSDUCTION; STATISTICS, NONPARAMETRIC; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 77956966710     PISSN: 00992399     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joen.2010.05.013     Document Type: Article

References (26)

1. J.O. Andreasen, M.K. Borum, H.L. Jacobsen, and F.M. Andreasen Replantation of 400 avulsed permanent incisors: 2 - factors related to pulpal healing Endod Dent Traumatol 11 1995 59 68
2. J.O. Andreasen, F.M. Andreasen, L.K. Bakland, and M.T. Flores Traumatic dental injuries 2nd ed. 2000 Blackwell Munksgaard Copenhagen, Denmark
3. J. Folkman, and Y. Shing Angiogenesis J Biol Chem 267 1992 10931 10934
4. C.W. Pugh, and P.J. Ratcliffe Regulation of angiogenesis by hypoxia: role of the HIF system Nat Med 9 2003 677 684
5. B.H. Jiang, E. Rue, G.L. Wang, R. Roe, and G.L. Semenza Dimerization, DNA binding and transactivation properties of hypoxia inducible factor 1 J Biol Chem 271 1996 17771 17778
6. G.L. Semenza, and G.L. Wang A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation Mol Cell Biol 12 1992 5447 5454
7. G.L. Wang, B.H. Jiang, E.A. Rue, and G.L. Semenza Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cell OXYGEN tension Proc Natl Acad Sci 92 1995 5510 5514
8. J.A. Forsythe, B.H. Jiang, and N.V. Iyer Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1 Mol Cell Biol 16 1996 4604 4613
9. B.D. Kelly, S.F. Hackett, and K. Hirota Cell type-specific regulation of angiogenic growth factor gene expression and induction of angiogenesis in nonischemic tissue by a constitutively active form of hypoxia-inducible factor 1 Circ Res 93 2003 1074 1081
10. D.J. Manalo, A. Rowan, and T. Lavoie Transcriptional regulation of vascular endothelial cell responses to hypoxia Blood 105 2005 659 669
11. L. Tran-Hung, P. Laurent, and I. Camps About Quantification of angiogenic growth factors released by human dental cells after injury Arch Oral Biol 53 2008 9 13
12. M. Yamakawa, L.X. Liu, and T. Date Hypoxia-inducible factor-1 mediates activation of cultured vascular endothelial cells by inducing multiple angiogenic factors Circ Res 93 2003 664 673
13. S. Koch, C. Yao, G. Grieb, P. Prevel, E.M. Noah, and G.C.M. Steffens Enhancing angiogenesis in collagen matrices by covalent incorporation of VEGF J Mater Sci Mater Med 17 2006 735 741
14. J.E. Nör, J. Christensen, D.J. Mooney, and P.J. Polverini Vascular endothelial growth factor (VEGF)-mediated angiogenesis is associated with enhanced endothelial cell survival and induction of Bcl-2 expression Am J Pathol 154 1999 375 384
15. L.E. Benjamin, I. Hemo, and E. Keshet A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF Development 125 1998 1591 1598
16. H.C. Haspel, G.M. Scicli, G. McMahon, and G.M. Scicli Inhibition of vascular endothelial growth factor-associated tyrosine kinase activity with SU5416 blocks sprouting in the microvascular endothelial cell spheroid model of angiogenesis Microvasc Res 63 2002 304 315
17. E.M. Mullane, Z. Dong, and C.M. Sedgley Effect of VEGF on the revascularization of severed human dental pulps J Dent Res 87 2008 1144 1148
18. L. Tran-Hung, S. Mathieu, and I. About Role of human pulp fibroblasts in angiogenesis J Dent Res 85 2006 819 823
19. G.L. Wang, and G.L. Semenza Purification and characterization of hypoxia-inducible factor 1 J Biol Chem 270 1995 1230 1237
20. J. Höper Spectrophotometric in vivo determination of local mitochondrial metabolism by use of a tetrazolium salt Physiol Meas 18 1997 61 66
21. S.L. Pan, J.H. Guh, and C.Y. Peng YC-1 [3-(5'-hydroxymethyl-2'-furyl)-1- benzyl indazole] inhibits endothelial cell functions induced by angiogenic factors in vitro and angiogenesis in vivo models J Pharmacol Exp Ther 314 2005 35 42
22. Y. Dai, M. Xu, Y. Wang, Z. Pasha, T. Li, and M. Ashraf HIF-1alpha induced-VEGF over-expression in bone marrow stem cells protects cardiomyocytes against ischemia J Mol Cell Cardiol 42 2007 1036 1044
23. J. Ke, Y. Liu, and X. Long Up-regulation of vascular endothelial growth factor in synovial fibroblasts from human timeromandibular joint by hypoxia J Oral Pathol Med 36 2007 290 296
24. B.H. Jiang, G.L. Semenza, C. Bauer, and H.H. Marti Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of oxygen tension Am J Physiol 271 1996 C1172 C1180
25. P. Carmeliet, V. Ferreira, and G. Breier Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele Nature 380 1996 435 439
26. J. Fang, L. Yan, Y. Shing, and M.A. Moses HIF-1alpha-mediated up-regulation of vascular endothelial growth factor, independent of basic fibroblast growth factor, is important in the switch to the angiogenic phenotype during early tumorigenesis Cancer Res 61 2001 5731 5735