Lentivirus-mediated RNA interference of vascular endothelial growth factor in monkey eyes with iris neovascularization

Molecular Vision

Volumn 16, Issue , 2010, Pages 1743-1753

  Yuan, Meng Ke ^a   Tao, Yong ^a   Yu, Wen Zhen ^a   Kai, Wang ^a   Jiang, Yan Rong ^a  

^a PEKING UNIVERSITY PEOPLE S HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

GREEN FLUORESCENT PROTEIN; LENTIVIRUS VECTOR; SHORT HAIRPIN RNA; VASCULOTROPIN A; VASCULOTROPIN ANTIBODY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL STRAIN; CELL STRAIN H1299; CONTROLLED STUDY; ECTROPION; EYE SYNECHIA; GENE SILENCING; GENE THERAPY; HUMAN; HUMAN CELL; HYPHEMA; IRIS BLOOD VESSEL; IRIS DISEASE; IRIS NEOVASCULARIZATION; LASER COAGULATION; MONKEY; NONHUMAN; PRIORITY JOURNAL; RETINA VEIN OCCLUSION; RNA INTERFERENCE; RNA SEQUENCE; VIRAL GENE DELIVERY SYSTEM; VIRUS PARTICLE; VIRUS RECOMBINANT;

ANIMALS; DISEASE MODELS, ANIMAL; FLUORESCEIN ANGIOGRAPHY; GREEN FLUORESCENT PROTEINS; HAPLORHINI; IMMUNOHISTOCHEMISTRY; IRIS; LENTIVIRUS; NEOVASCULARIZATION, PATHOLOGIC; RNA INTERFERENCE; RNA, SMALL INTERFERING; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 77956955088     PISSN: None     EISSN: 10900535     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Sivak-Callcott JA, O'Day DM, Gass JD, Tsai JC. Evidencebased recommendations for the diagnosis and treatment of neovascular glaucoma. Ophthalmology 2001; 108:1767-1776.
2. Ferrara N. Role of vascular endothelial growth factor in physiologic and pathologic angiogenesis: therapeutic implications. Semin Oncol 2002; 29:10-14.
3. Aiello LP, Avery RL, Arrigg PG, Keyt BA, Jampel HD, Shah ST, Pasquale LR, Thieme H, Iwamoto MA, Park JE, Nguyen HV, Aiello LM, Ferrara N, King GL. Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders. N Engl J Med 1994; 331:1480-1487.
4. Tripathi RC, Li J, Tripathi BJ, Chalam KV, Adamis AP. Increased level of vascular endothelial growth factor in aqueous humor of patients with neovascular glaucoma. Ophthalmology 1998; 105:232-237.
5. Graham CE, Binz N, Shen WY, Constable IJ, Rakoczy EP. Laser photocoagulation: ocular research and therapy in diabetic retinopathy. Adv Exp Med Biol 2006; 572:195-200.
6. Sedney SC. Photocoagulation in retinal vein occlusion. Doc Ophthalmol 1976; 40:1-241.
7. Chalam KV, Gupta SK, Grover S, Brar VS, Agarwal S. Intracameral Avastin dramatically resolves iris neovascularization and reverses neovascular glaucoma. Eur J Ophthalmol 2008; 18:255-262.
8. Jiang Y, Liang X, Li X, Tao Y, Wang K. Analysis of the clinical efficacy of intravitreal bevacizumab in the treatment of iris neovascularization caused by proliferative diabetic retinopathy. Acta Ophthalmol. 2008 [PMID: 18320519]
9. Wakabayashi T, Oshima Y, Sakaguchi H, Ikuno Y, Miki A, Gomi F, Otori Y, Kamei M, Kusaka S, Tano Y. Intravitreal bevacizumab to treat iris neovascularization and neovascular glaucoma secondary to ischemic retinal diseases in 41 consecutive cases. Ophthalmology 2008; 115:1571-1580.
10. Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC. Potent and specific genetic interference by doublestranded RNA in Caenorhabditis elegans. Nature 1998; 391:806-811.
11. Reich SJ, Fosnot J, Kuroki A, Tang W, Yang X, Maguire AM, Bennett J, Tolentino MJ. Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model. Mol Vis 2003; 9:210-216.
12. Shen J, Samul R, Silva RL, Akiyama H, Liu H, Saishin Y, Hackett SF, Zinnen S, Kossen K, Fosnaugh K, Vargeese C, Gomez A, Bouhana K, Aitchison R, Pavco P, Campochiaro PA. Suppression of ocular neovascularization with siRNA targeting VEGF receptor 1. Gene Ther 2006; 13:225-234.
13. Cheng L, Toyoguchi M, Looney DJ, Lee J, Davidson MC, Freeman WR. Efficient gene transfer to retinal pigment epithelium cells with long-term expression. Retina 2005; 25:193-201.
14. Tschernutter M, Schlichtenbrede FC, Howe S, Balaggan KS, Munro PM, Bainbridge JW, Thrasher AJ, Smith AJ, Ali RR. Long-term preservation of retinal function in the RCS rat model of retinitis pigmentosa following lentivirus-mediated gene therapy. Gene Ther 2005; 12:694-701.
15. Miller JW, Adamis AP, Shima DT, D'Amore PA, Moulton RS, O'Reilly MS, Folkman J, Dvorak HF, Brown LF, Berse B, Yeo TK, Yeo KT. Vascular endothelial growth factor/vascular permeability factor is temporally and spatially correlated with ocular angiogenesis in a primate model. Am J Pathol 1994; 145:574-584.
16. Akiyama H. Inhibition of Ocular Angiogenesis by an Adenovirus Carrying the Human von Hippel-Lindau Tumor-Suppressor Gene In Vivo. Invest Ophthalmol Vis Sci 2004; 45:1289-1296.
17. Nork TM, Tso MO, Duvall J, Hayreh SS. Cellular mechanisms of iris neovascularization secondary to retinal vein occlusion. Arch Ophthalmol 1989; 107:581-586.
18. Noel Weidner. Current pathologic methods for measuring intratumoral microvessel density within breast carcinoma and other solid tumors. Breast Cancer Res Treat 1995; 36:169-180.
19. Guo-You Zhang. Inhibition of vascular endothelial growth factor expression in keloid Wbroblasts by vector-mediated vascular endothelial growth factor shRNA: a therapeutic potential strategy for keloid. Arch Dermatol Res 2008; 300:177-184.
20. Fan XQ, Li J, Fu Y, Jia RB, Lu WJ. Small interference RNA targeting vascular endothelial growth factor inhibits rat corneal neovascularization. Zhonghua yan ke za zhi 2009; 45:746-751.
21. Murata M, Takanami T, Shimizu S, Kubota Y, Horiuchi S, Habano W, Ma JX, Sato S. Inhibition of ocular angiogenesis by diced small interfering RNAs (siRNAs) specific to vascular endothelial growth factor (VEGF). Curr Eye Res 2006; 31:171-180.
22. Wang S, Liu H, Ren L, Pan Y, Zhang Y. Inhibiting colorectal carcinoma growth and metastasis by blocking the expression of VEGF using RNA interference. Neoplasia 2008; 10:399-407.
23. He XW, Yu X, Liu T, Yu SY, Chen DJ. Vector-based RNA interference against vascular endothelial growth factor-C inhibits tumor lymphangiogenesis and growth of colorectal cancer in vivo in mice. Chin Med J (Engl) 2008; 121:439-444.
24. Guo B, Zhang Y, Luo G, Li L, Zhang J. Lentivirus-mediated small interfering RNA targeting VEGF-C inhibited tumor lymphangiogenesis and growth in breast carcinoma. Anat Rec (Hoboken) 2009; 292:633-639.
25. Duxbury MS, Whang EE. RNA interference: a practical approach. J Surg Res 2004; 117:339-344.
26. Dave RS, Pomerantz RJ. RNA interference: on the road to an alternate therapeutic strategy! Rev Med Virol 2003; 13:373-385.
27. Salmon P, Kindler V, Ducrey O, Chapuis B, Zubler RH, Trono D. High-level transgene expression in human hematopoietic progenitors and differentiated blood lineages after transduction with improved lentiviral vectors. Blood 2000; 96:3392-3398.
28. Schomber T, Kalberer CP, Wodnar-Filipowicz A, Skoda RC. Gene silencing by lentivirus-mediated delivery of siRNA in human CD34+ cells. Blood 2004; 103:4511-4513.