Priming the immune system for heart disease: A perspective on group a streptococci

Journal of Infectious Diseases

Volumn 202, Issue 7, 2010, Pages 1059-1067

  Ellis, Nadia M J ^a   Kurahara, David K ^c,d   Vohra, Harpreet ^f,g,h   Mascaro Blanco, Adita ^a   Erdem, Guliz ^c   Adderson, Elisabeth E ^e   Veasy, L George ^e   Stoner, Julie A ^e   Tam, Elizabeth ^b   Hill, Harry R ^c   Yamaga, Karen ^c   Cunningham, Madeleine W ^a  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

^c UNIVERSITY OF HAWAII   (United States)

^d Kapi'olani Medical Center for Women and Children   (United States)

^e UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^f POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

^g Australian National University   (Australia)

^h ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISTREPTOLYSIN; BACTERIAL PROTEIN; CARDIAC MYOSIN; EPITOPE; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G ANTIBODY; M PROTEIN; MYOSIN HEAVY CHAIN BETA; MYOSIN LIGHT CHAIN; MYOSIN SUBFRAGMENT; MYOSIN SUBFRAGMENT 1; MYOSIN SUBFRAGMENT 2; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANTIBODY RESPONSE; ARTICLE; CARDITIS; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GROUP A STREPTOCOCCAL INFECTION; HUMAN; IMMUNOREACTIVITY; INDIA; MOLECULAR MIMICRY; NONHUMAN; PACIFIC ISLANDER; PATHOGENESIS; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN STRUCTURE; RHEUMATIC FEVER; RHEUMATIC HEART DISEASE; SEROTYPE; STREPTOCOCCAL PHARYNGITIS; STREPTOCOCCUS GROUP A; UNITED STATES; CHILD; EPITOPE MAPPING; FEMALE; IMMUNOLOGY; MALE; PRESCHOOL CHILD; STREPTOCOCCUS PYOGENES;

CARDIAC MYOSINS; CHILD; CHILD, PRESCHOOL; EPITOPE MAPPING; EPITOPES; FEMALE; HUMANS; IMMUNOGLOBULIN G; MALE; RHEUMATIC HEART DISEASE; STREPTOCOCCUS PYOGENES;

EID: 77956917627     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/656214     Document Type: Article

References (39)

1. Kaur S, Kumar D, Grover A, et al. Ethnic differences in expression of susceptibility marker(s) in rheumatic fever/rheumatic heart disease patients. Int J Cardiol 1998; 64:9-14.
2. WHO programme for the prevention of rheumatic fever/rheumatic heart disease in 16 developing countries: report from phase 1 (1986-90). Bull World Health Organ 1992; 70:213-218.
3. McDonald M, Currie BJ, Carapetis JR. Acute rheumatic fever: a chink in the chain that links the heart to the throat? Lancet Infect Dis 2004; 4(4):240-245.
4. Martin DR, Meekin GE, Finch LA. Streptococci - are they different in New Zealand? N Z Med J 1983; 96:298-301.
5. Kurahara D, Tokuda A, Grandinetti A, et al. Ethnic differences in risk for pediatric rheumatic illness in a culturally diverse population. J Rheumatol 2002; 29(2):379-383.
6. Veasy LG, Tani LY, Hill HR. Persistence of acute rheumatic fever in the intermountain area of the United States. J Pediatr 1994; 124:9-16.
7. Veasy LG, Wiedmeier SE, Orsmond GS, et al. Resurgence of acute rheumatic fever in the intermountain area of the United States. N Engl J Med 1987; 316(8):421-427. (Pubitemid 17035568)
8. Kaplan EL, Johnson DR, Cleary PP. Group A streptococcal serotypes isolated from patients and sibling contacts during the resurgence of rheumatic fever in the United states in the mid-1980s. J Infect Dis 1989; 159:101-103.
9. Stollerman GH. Rheumatic fever. Lancet 1997; 349:935-942.
10. Veasy LG, Tani LY. A new look at acute rheumatic mitral regurgitation. Cardiol Young 2005; 15(6):568-577.
11. Veasy LG. Rheumatic fever. Lancet Infect Dis 2004; 4(11):661.
12. Roberts S, Kosanke S, Dunn ST, Jankelow D, Duran CMG, Cunningham MW. Immune mechanisms in rheumatic carditis: focus on valvular endothelium. J Infect Dis 2001; 183:507-511.
13. Zabriskie JB, Hsu KC, Seegal BC. Heart-reactive antibody associated with rheumatic fever: characterization and diagnostic significance. Clin Exp Immunol 1970; 7:147-159.
14. Krisher K, Cunningham MW. Myosin: a link between streptococci and heart. Science 1985; 227(4685):413-415.
15. Galvin JE, Hemric ME, Ward K, Cunningham MW. Cytotoxic monoclonal antibody from rheumatic carditis reacts with human endothelium: implications in rheumatic heart disease. J Clin Invest 2000; 106:217-224.
16. Martins TB, Hoffman JL, Augustine NH, et al. Comprehensive analysis of antibody responses to streptococcal and tissue antigens in patients with acute rheumatic fever. Int Immunol 2008; 20(3):445-452.
17. Fae KC, da Silva DD, Oshiro SE, et al. Mimicry in recognition of cardiac myosin peptides by heart-intralesional T cell clones from rheumatic heart disease. J Immunol 2006; 176(9):5662-5670.
18. Quinn A, Kosanke S, Fischetti VA, Factor SM, Cunningham MW. Induction of autoimmune valvular heart disease by recombinant streptococcal M protein. Infect Immun 2001; 69(6):4072-4078.
19. Galvin JE, Hemric ME, Kosanke SD, Factor SM, Quinn A, Cunningham MW. Induction of myocarditis and valvulitis in Lewis rats by different epitopes of cardiac myosin and its implications in rheumatic carditis. Am J Pathol 2002; 160:297-306. (Pubitemid 34052290)
20. Gerber MA, Baltimore RS, Eaton CB, et al. Prevention of rheumatic fever and diagnosis and treatment of acute streptococcal pharyngitis: a scientific statement from the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee of the Council on Cardiovascular Disease in the Young, the Interdisciplinary Council on Functional Genomics and Translational Biology, and the Interdisciplinary Council on Quality of Care and Outcomes Research. Circulation 2009; 119(11):1541-1551.
21. Jaenicke T, Diederich KW, Haas W, et al. Complete sequence of human b myosin. Genomics 1990; 8:194-207.
22. Li Y, Heuser JS, Kosanke SD, Hemric M, Cunningham MW. Cryptic epitope identified in rat and human cardiac myosin S2 region induces myocarditis in the Lewis rat. J Immunol 2004; 172:3225-3234.
23. Cunningham MW, Meissner HC, Heuser J, Leung DYM. Anti-human cardiac myosin autoantibodies in Kawasaki syndrome. J Immunol 1999; 163:1060-1065.
24. Benjamin Y, Hochberg Y. Controlling the false discovery: a practical and powerful approach to multiple testing. J R Stat Soc 1995; 57(series B):289-300.
25. Mehra NK, Taneja V, Kailash S, Raizada N, Vaidya MC. Distribution of HLA antigens in a sample of the North Indian Hindu population. Tissue Antigens 1986; 27(2):64-74. (Pubitemid 16154457)
26. Jaini R, Kaur G, Mehra NK. Heterogeneity of HLA-DRB1*04 and its associated haplotypes in the North Indian population. Hum Immunol 2002; 63(1):24-29.
27. Cunningham MW. Pathogenesis of group a streptococcal infections. Clin Microbiol Rev 2000; 13:470-511.
28. Neu N, Beisel KW, Traystman MD, Rose NR, Craig SW. Autoantibodies specific for the cardiac myosin isoform are found in mice susceptible to coxsackievirus B3 induced myocarditis. J Immunol 1987; 138:2488-2492. (Pubitemid 17051821)
29. Cunningham MW, Antone SM, Smart M, Liu R, Kosanke S. Molecular analysis of human cardiac myosin-cross-reactive B- and T-cell epitopes of the group A streptococcal M5 protein. Infect Immun 1997; 65:3913-3923.
30. Ellis NMJ, Li Y, Hildebrand W, Fischetti VA, Cunningham MW. T cell mimicry and epitope specificity of crossreactive T cell clones from rheumatic heart disease. J Immunol 2005; 175:5448-5456. (Pubitemid 41456431)
31. Beall B, Facklam R, Thompson T. Sequencing emm-specific PCR products for routine and accurate typing of group A streptococci. J Clin Microbiol 1996; 34:953-958.
32. Bisno AL, Brito MO, Collins CM. Molecular basis of group A streptococcal virulence. Lancet Infect Dis 2003; 3(4):191-200.
33. Kaplan EL. The resurgence of group A streptococcal infections and their sequelae [editorial]. Eur J Clin Microbiol Infect Dis 1991; 10(2):55-57.
34. Erdem G, Mizumoto C, Esaki D, et al. Group A streptococcal isolates temporally associated with acute rheumatic fever in Hawaii: differences from the continental United States. Clin Infect Dis 2007; 45:e20-24.
35. Hartas J, Goodfellow AM, Currie BJ, Sriprakash KS. Characterisation of group A streptococcal isolates from tropical Australia with high prevalence of rehumatic fever: probing the signature sequences to identify members of the family of serotype 5. Microb Pathog 1995; 18:345-354.
36. Shikhman AR, Greenspan NS, Cunningham MW. Cytokeratin peptide SFGSGFGGGY mimics N-acetyl-beta-D-glucosamine in reaction with antibodies and lectins, and induces in vivo anti-carbohydrate antibody response. J Immunol 1994; 153(12):5593-5606.
37. Shikhman AR, Greenspan NS, Cunningham MW. A subset of mouse monoclonal antibodies cross-reactive with cytoskeletal proteins and group A streptococcal M proteins recognizes N-acetyl-beta-D-glucosamine. J Immunol 1993; 151(7):3902-3913.
38. Gulizia JM, Cunningham MW, McManus BM. Immunoreactivity of anti-streptococcal monoclonal antibodies to human heart valves. Evidence for multiple cross-reactive epitopes. Am J Pathol 1991; 138(2):285-301.
39. Guilherme L, Cury P, Demarchi LMF, et al. Rheumatic heart disease: pro-inflammatory cytokines play a role in the progression and maintenance of valvular lesions. Am J Pathol 2004; 165:1583-1591.