Prolonged mechanical unloading preserves myocardial contractility but impairs relaxation in rat heart of dilated cardiomyopathy accompanied by myocardial stiffness and apoptosis

Journal of Thoracic and Cardiovascular Surgery

Volumn 140, Issue 4, 2010, Pages 916-922

  Muranaka, Hiroyuki ^a   Marui, Akira ^a   Tsukashita, Masaki ^a   Wang, Jian ^a   Nakano, Jota ^a   Ikeda, Tadashi ^a   Sakata, Ryuzo ^a  

^a KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; ISOPRENALINE; MESSENGER RNA; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; COLLAGEN TYPE 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CLINICAL EVALUATION; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; HEART MUSCLE CONTRACTILITY; HEART MUSCLE RELAXATION; HEART PAPILLARY MUSCLE; HEART TRANSPLANTATION; MUSCLE CELL; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; CARDIOMYOPATHY, DILATED; DIASTOLE; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECTS; ELASTICITY; FIBROSIS; GENETICS; HEART ASSIST DEVICE; HEART CONTRACTION; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE; LEWIS RAT; MALE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; SYSTOLE; TIME;

ADRENERGIC BETA-AGONISTS; ANIMALS; APOPTOSIS; CARDIOMYOPATHY, DILATED; COLLAGEN TYPE I; DIASTOLE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ELASTICITY; FIBROSIS; HEART TRANSPLANTATION; HEART-ASSIST DEVICES; ISOPROTERENOL; MALE; MYOCARDIAL CONTRACTION; MYOCARDIUM; PAPILLARY MUSCLES; RATS; RATS, INBRED LEW; RNA, MESSENGER; SYSTOLE; TIME FACTORS; VENTRICULAR FUNCTION, LEFT;

EID: 77956878648     PISSN: 00225223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jtcvs.2010.02.006     Document Type: Article

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