메뉴 건너뛰기




Volumn 9, Issue , 2010, Pages

Kinome profiling of myxoid liposarcoma reveals NF-kappaB-pathway kinase activity and Casein Kinase II inhibition as a potential treatment option

Author keywords

[No Author keywords available]

Indexed keywords

4,5,6,7 TETRABROMOBENZOTRIAZOLE; CASEIN KINASE II; CASPASE 3; DASATINIB; ENZYME INHIBITOR; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; HYBRID PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; KINOME; PROTEIN FUS; PROTEIN KINASE; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG; 4,5,6,7-TETRABROMOBENZOTRIAZOLE; ONCOPROTEIN; PROTEIN KINASE INHIBITOR; PYRIMIDINE DERIVATIVE; THIAZOLE DERIVATIVE; TRIAZOLE DERIVATIVE;

EID: 77956877001     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-9-257     Document Type: Article
Times cited : (29)

References (59)
  • 2
    • 77950358766 scopus 로고    scopus 로고
    • Running GAGs: myxoid matrix in tumor pathology revisited: What's in it for the pathologist?
    • 10.1007/s00428-009-0822-y, 2828560, 19705152
    • Willems SM, Wiweger M, Graadt van Roggen JF, Hogendoorn PCW. Running GAGs: myxoid matrix in tumor pathology revisited: What's in it for the pathologist?. Virchows Arch 2010, 456:181-192. 10.1007/s00428-009-0822-y, 2828560, 19705152.
    • (2010) Virchows Arch , vol.456 , pp. 181-192
    • Willems, S.M.1    Wiweger, M.2    Graadt van Roggen, J.F.3    Hogendoorn, P.C.W.4
  • 3
    • 0022970519 scopus 로고
    • Cytogenetic studies of adipose tissue tumors. II. Recurrent reciprocal translocation t(12;16)(q13;p11) in myxoid liposarcomas
    • 10.1016/0165-4608(86)90011-7, 3779625
    • Turc-Carel C, Limon J, Dal Cin P, Rao U, Karakousis C, Sandberg AA. Cytogenetic studies of adipose tissue tumors. II. Recurrent reciprocal translocation t(12;16)(q13;p11) in myxoid liposarcomas. Cancer Genet Cytogenet 1986, 23:291-299. 10.1016/0165-4608(86)90011-7, 3779625.
    • (1986) Cancer Genet Cytogenet , vol.23 , pp. 291-299
    • Turc-Carel, C.1    Limon, J.2    Dal Cin, P.3    Rao, U.4    Karakousis, C.5    Sandberg, A.A.6
  • 8
    • 40549131053 scopus 로고    scopus 로고
    • Diagnosis and management of lipomatous tumors
    • 10.1002/jso.20975, 18286473
    • Dalal KM, Antonescu CR, Singer S. Diagnosis and management of lipomatous tumors. J Surg Oncol 2008, 97:298-313. 10.1002/jso.20975, 18286473.
    • (2008) J Surg Oncol , vol.97 , pp. 298-313
    • Dalal, K.M.1    Antonescu, C.R.2    Singer, S.3
  • 9
    • 34548706418 scopus 로고    scopus 로고
    • Replication and homologous recombination repair regulate DNA double-strand break formation by the antitumor alkylator ecteinascidin 743
    • 10.1073/pnas.0609877104, 1941813, 17656556
    • Soares DG, Escargueil AE, Poindessous V, Sarasin A, de Gramont A, Bonatto D, Henriques JA, Larsen AK. Replication and homologous recombination repair regulate DNA double-strand break formation by the antitumor alkylator ecteinascidin 743. Proc Natl Acad Sci USA 2007, 104:13062-13067. 10.1073/pnas.0609877104, 1941813, 17656556.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 13062-13067
    • Soares, D.G.1    Escargueil, A.E.2    Poindessous, V.3    Sarasin, A.4    de Gramont, A.5    Bonatto, D.6    Henriques, J.A.7    Larsen, A.K.8
  • 10
    • 0029838307 scopus 로고    scopus 로고
    • DNA sequence- and structure-selective alkylation of guanine N2 in the DNA minor groove by ecteinascidin 743, a potent antitumor compound from the Caribbean tunicate Ecteinascidia turbinata
    • 10.1021/bi960306b, 8873596
    • Pommier Y, Kohlhagen G, Bailly C, Waring M, Mazumder A, Kohn KW. DNA sequence- and structure-selective alkylation of guanine N2 in the DNA minor groove by ecteinascidin 743, a potent antitumor compound from the Caribbean tunicate Ecteinascidia turbinata. Biochemistry 1996, 35:13303-13309. 10.1021/bi960306b, 8873596.
    • (1996) Biochemistry , vol.35 , pp. 13303-13309
    • Pommier, Y.1    Kohlhagen, G.2    Bailly, C.3    Waring, M.4    Mazumder, A.5    Kohn, K.W.6
  • 11
    • 0033566150 scopus 로고    scopus 로고
    • Ecteinascidin 743: a minor groove alkylator that bends DNA toward the major groove
    • 10.1021/jm990241l, 10411470
    • Zewail-Foote M, Hurley LH. Ecteinascidin 743: a minor groove alkylator that bends DNA toward the major groove. J Med Chem 1999, 42:2493-2497. 10.1021/jm990241l, 10411470.
    • (1999) J Med Chem , vol.42 , pp. 2493-2497
    • Zewail-Foote, M.1    Hurley, L.H.2
  • 12
    • 73949121479 scopus 로고    scopus 로고
    • Recognition of a new chemotherapeutic vesicant: trabectedin (ecteinascidin-743) extravasation with skin and soft tissue damage
    • 10.1200/JCO.2008.21.6473, 19805684
    • Theman TA, Hartzell TL, Sinha I, Polson K, Morgan J, Demetri GD, Orgill DP, George S. Recognition of a new chemotherapeutic vesicant: trabectedin (ecteinascidin-743) extravasation with skin and soft tissue damage. J Clin Oncol 2009, 27:e198-e200. 10.1200/JCO.2008.21.6473, 19805684.
    • (2009) J Clin Oncol , vol.27
    • Theman, T.A.1    Hartzell, T.L.2    Sinha, I.3    Polson, K.4    Morgan, J.5    Demetri, G.D.6    Orgill, D.P.7    George, S.8
  • 14
    • 0034949674 scopus 로고    scopus 로고
    • Signal transduction pathways in sarcoma as targets for therapeutic intervention
    • 10.1097/00001622-200107000-00007, 11429482
    • Tuveson DA, Fletcher JA. Signal transduction pathways in sarcoma as targets for therapeutic intervention. Curr Opin Oncol 2001, 13:249-255. 10.1097/00001622-200107000-00007, 11429482.
    • (2001) Curr Opin Oncol , vol.13 , pp. 249-255
    • Tuveson, D.A.1    Fletcher, J.A.2
  • 15
    • 38049025794 scopus 로고    scopus 로고
    • Review: side effects of approved molecular targeted therapies in solid cancers
    • 10.1634/theoncologist.12-12-1443, 18165622
    • Widakowich C, de CG, de Azambuja E, Dinh P, Awada A. Review: side effects of approved molecular targeted therapies in solid cancers. Oncologist 2007, 12:1443-1455. 10.1634/theoncologist.12-12-1443, 18165622.
    • (2007) Oncologist , vol.12 , pp. 1443-1455
    • Widakowich, C.1    de, C.G.2    de Azambuja, E.3    Dinh, P.4    Awada, A.5
  • 17
    • 18544379762 scopus 로고    scopus 로고
    • Myxoid liposarcoma FUS-DDIT3 fusion oncogene induces C/EBP beta-mediated interleukin 6 expression
    • 10.1002/ijc.20893, 15688424
    • Goransson M, Elias E, Stahlberg A, Olofsson A, Andersson C, Aman P. Myxoid liposarcoma FUS-DDIT3 fusion oncogene induces C/EBP beta-mediated interleukin 6 expression. Int J Cancer 2005, 115:556-560. 10.1002/ijc.20893, 15688424.
    • (2005) Int J Cancer , vol.115 , pp. 556-560
    • Goransson, M.1    Elias, E.2    Stahlberg, A.3    Olofsson, A.4    Andersson, C.5    Aman, P.6
  • 19
    • 58249116717 scopus 로고    scopus 로고
    • The myxoid liposarcoma FUS-DDIT3 fusion oncoprotein deregulates NF-kappaB target genes by interaction with NFKBIZ
    • 10.1038/onc.2008.378, 18850010
    • Goransson M, Andersson MK, Forni C, Stahlberg A, Andersson C, Olofsson A, Mantovani R, Aman P. The myxoid liposarcoma FUS-DDIT3 fusion oncoprotein deregulates NF-kappaB target genes by interaction with NFKBIZ. Oncogene 2009, 28:270-278. 10.1038/onc.2008.378, 18850010.
    • (2009) Oncogene , vol.28 , pp. 270-278
    • Goransson, M.1    Andersson, M.K.2    Forni, C.3    Stahlberg, A.4    Andersson, C.5    Olofsson, A.6    Mantovani, R.7    Aman, P.8
  • 20
    • 33745298519 scopus 로고    scopus 로고
    • Nuclear factor-kappaB in cancer development and progression
    • 10.1038/nature04870, 16724054
    • Karin M. Nuclear factor-kappaB in cancer development and progression. Nature 2006, 441:431-436. 10.1038/nature04870, 16724054.
    • (2006) Nature , vol.441 , pp. 431-436
    • Karin, M.1
  • 21
    • 0036717195 scopus 로고    scopus 로고
    • Nf-kappa B, chemokine gene transcription and tumour growth
    • 10.1038/nri887, 2668257, 12209135
    • Richmond A. Nf-kappa B, chemokine gene transcription and tumour growth. Nat Rev Immunol 2002, 2:664-674. 10.1038/nri887, 2668257, 12209135.
    • (2002) Nat Rev Immunol , vol.2 , pp. 664-674
    • Richmond, A.1
  • 22
  • 23
    • 0035805108 scopus 로고    scopus 로고
    • Selectivity of 4,5,6,7-tetrabromobenzotriazole, an ATP site-directed inhibitor of protein kinase CK2 ('casein kinase-2')
    • 10.1016/S0014-5793(01)02404-8, 11343704
    • Sarno S, Reddy H, Meggio F, Ruzzene M, Davies SP, Donella-Deana A, Shugar D, Pinna LA. Selectivity of 4,5,6,7-tetrabromobenzotriazole, an ATP site-directed inhibitor of protein kinase CK2 ('casein kinase-2'). FEBS Lett 2001, 496:44-48. 10.1016/S0014-5793(01)02404-8, 11343704.
    • (2001) FEBS Lett , vol.496 , pp. 44-48
    • Sarno, S.1    Reddy, H.2    Meggio, F.3    Ruzzene, M.4    Davies, S.P.5    Donella-Deana, A.6    Shugar, D.7    Pinna, L.A.8
  • 24
    • 70349320107 scopus 로고    scopus 로고
    • Protein kinase CK2 in health and disease: CK2: a key player in cancer biology
    • 10.1007/s00018-009-9154-y, 19387548
    • Trembley JH, Wang G, Unger G, Slaton J, Ahmed K. Protein kinase CK2 in health and disease: CK2: a key player in cancer biology. Cell Mol Life Sci 2009, 66:1858-1867. 10.1007/s00018-009-9154-y, 19387548.
    • (2009) Cell Mol Life Sci , vol.66 , pp. 1858-1867
    • Trembley, J.H.1    Wang, G.2    Unger, G.3    Slaton, J.4    Ahmed, K.5
  • 25
    • 63449112585 scopus 로고    scopus 로고
    • Therapeutic protein kinase inhibitors
    • 10.1007/s00018-008-8539-7, 19011754
    • Grant SK. Therapeutic protein kinase inhibitors. Cell Mol Life Sci 2009, 66:1163-1177. 10.1007/s00018-008-8539-7, 19011754.
    • (2009) Cell Mol Life Sci , vol.66 , pp. 1163-1177
    • Grant, S.K.1
  • 26
    • 49749093990 scopus 로고    scopus 로고
    • FUS-DDIT3 prevents the development of adipocytic precursors in liposarcoma by repressing PPARgamma and C/EBPalpha and activating eIF4E
    • 10.1371/journal.pone.0002569, 2434200, 18596980
    • Perez-Mancera PA, Bermejo-Rodriguez C, Sanchez-Martin M, Abollo-Jimenez F, Pintado B, Sanchez-Garcia I. FUS-DDIT3 prevents the development of adipocytic precursors in liposarcoma by repressing PPARgamma and C/EBPalpha and activating eIF4E. PLoS One 2008, 3:e2569. 10.1371/journal.pone.0002569, 2434200, 18596980.
    • (2008) PLoS One , vol.3
    • Perez-Mancera, P.A.1    Bermejo-Rodriguez, C.2    Sanchez-Martin, M.3    Abollo-Jimenez, F.4    Pintado, B.5    Sanchez-Garcia, I.6
  • 27
    • 50649097541 scopus 로고    scopus 로고
    • Fat and beyond: the diverse biology of PPARgamma
    • 10.1146/annurev.biochem.77.061307.091829, 18518822
    • Tontonoz P, Spiegelman BM. Fat and beyond: the diverse biology of PPARgamma. Annu Rev Biochem 2008, 77:289-312. 10.1146/annurev.biochem.77.061307.091829, 18518822.
    • (2008) Annu Rev Biochem , vol.77 , pp. 289-312
    • Tontonoz, P.1    Spiegelman, B.M.2
  • 28
    • 77957758578 scopus 로고    scopus 로고
    • Imaging mass spectrometry of myxoid sarcomas identifies proteins and lipids specific to tumour type and grade, and reveals biochemical intratumour heterogeneity
    • Willems SM, van RA, van ZR, Deelder AM, McDonnell LA, Hogendoorn PC. Imaging mass spectrometry of myxoid sarcomas identifies proteins and lipids specific to tumour type and grade, and reveals biochemical intratumour heterogeneity. J Pathol 2010,
    • (2010) J Pathol
    • Willems, S.M.1    van, R.A.2    van, Z.R.3    Deelder, A.M.4    McDonnell, L.A.5    Hogendoorn, P.C.6
  • 29
    • 0027227651 scopus 로고
    • Fusion of CHOP a novel RNA-binding protein in human myxoid liposarcoma
    • 10.1038/363640a0, 8510758
    • Crozat A, Aman P, Mandahl P, Ron D. Fusion of CHOP a novel RNA-binding protein in human myxoid liposarcoma. Nature 1993, 363:640-644. 10.1038/363640a0, 8510758.
    • (1993) Nature , vol.363 , pp. 640-644
    • Crozat, A.1    Aman, P.2    Mandahl, P.3    Ron, D.4
  • 30
    • 0030882823 scopus 로고    scopus 로고
    • Oncogenic transformation and inhibition of adipocytic conversion of preadipocytes by TLS/FUS-CHOP type II chimeric protein
    • 1857848, 9284822
    • Kuroda M, Ishida T, Takanashi M, Satoh M, Machinami R, Watanabe T. Oncogenic transformation and inhibition of adipocytic conversion of preadipocytes by TLS/FUS-CHOP type II chimeric protein. Am J Pathol 1997, 151:735-744. 1857848, 9284822.
    • (1997) Am J Pathol , vol.151 , pp. 735-744
    • Kuroda, M.1    Ishida, T.2    Takanashi, M.3    Satoh, M.4    Machinami, R.5    Watanabe, T.6
  • 31
    • 33746924453 scopus 로고    scopus 로고
    • Expression of the FUS-CHOP fusion protein in primary mesenchymal progenitor cells gives rise to a model of myxoid liposarcoma
    • 10.1158/0008-5472.CAN-05-3979, 16849546
    • Riggi N, Cironi L, Provero P, Suva ML, Stehle JC, Baumer K, Guillou L, Stamenkovic I. Expression of the FUS-CHOP fusion protein in primary mesenchymal progenitor cells gives rise to a model of myxoid liposarcoma. Cancer Res 2006, 66:7016-7023. 10.1158/0008-5472.CAN-05-3979, 16849546.
    • (2006) Cancer Res , vol.66 , pp. 7016-7023
    • Riggi, N.1    Cironi, L.2    Provero, P.3    Suva, M.L.4    Stehle, J.C.5    Baumer, K.6    Guillou, L.7    Stamenkovic, I.8
  • 32
    • 33646535436 scopus 로고    scopus 로고
    • The myxoid/round cell liposarcoma fusion oncogene FUS-DDIT3 and the normal DDIT3 induce a liposarcoma phenotype in transfected human fibrosarcoma cells
    • 10.2353/ajpath.2006.050872, 1606602, 16651630
    • Engstrom K, Willen H, Kabjorn-Gustafsson C, Andersson C, Olsson M, Goransson M, Jarnum S, Olofsson A, Warnhammar E, Aman P. The myxoid/round cell liposarcoma fusion oncogene FUS-DDIT3 and the normal DDIT3 induce a liposarcoma phenotype in transfected human fibrosarcoma cells. Am J Pathol 2006, 168:1642-1653. 10.2353/ajpath.2006.050872, 1606602, 16651630.
    • (2006) Am J Pathol , vol.168 , pp. 1642-1653
    • Engstrom, K.1    Willen, H.2    Kabjorn-Gustafsson, C.3    Andersson, C.4    Olsson, M.5    Goransson, M.6    Jarnum, S.7    Olofsson, A.8    Warnhammar, E.9    Aman, P.10
  • 33
    • 0033616795 scopus 로고    scopus 로고
    • Induction of solid tumor differentiation by the peroxisome proliferator-activated receptor-gamma ligand troglitazone in patients with liposarcoma
    • 10.1073/pnas.96.7.3951, 22401, 10097144
    • Demetri GD, Fletcher CDM, Mueller E, Sarraf P, Naujoks R, Campbell N, Spiegelman BM, Singer S. Induction of solid tumor differentiation by the peroxisome proliferator-activated receptor-gamma ligand troglitazone in patients with liposarcoma. Proc Natl Acad Sci USA 1999, 96:3951-3956. 10.1073/pnas.96.7.3951, 22401, 10097144.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 3951-3956
    • Demetri, G.D.1    Fletcher, C.D.M.2    Mueller, E.3    Sarraf, P.4    Naujoks, R.5    Campbell, N.6    Spiegelman, B.M.7    Singer, S.8
  • 34
    • 0242408156 scopus 로고    scopus 로고
    • A phase II trial with rosiglitazone in liposarcoma patients
    • 10.1038/sj.bjc.6601306, 2394353, 14562008
    • Debrock G, Vanhentenrijk V, Sciot R, Debiec-Rychter M, Oyen R, Van Oosterom A. A phase II trial with rosiglitazone in liposarcoma patients. Br J Cancer 2003, 89:1409-1412. 10.1038/sj.bjc.6601306, 2394353, 14562008.
    • (2003) Br J Cancer , vol.89 , pp. 1409-1412
    • Debrock, G.1    Vanhentenrijk, V.2    Sciot, R.3    Debiec-Rychter, M.4    Oyen, R.5    Van Oosterom, A.6
  • 35
    • 0041334078 scopus 로고    scopus 로고
    • Molecular variability of TLS-CHOP structure shows no significant impact on the level of adipogenesis: a comparative ultrastructural and RT-PCR analysis of 14 cases of myxoid/round cell liposarcomas
    • 10.1080/01913120309917, 12907366
    • Huang HY, Antonescu CR. Molecular variability of TLS-CHOP structure shows no significant impact on the level of adipogenesis: a comparative ultrastructural and RT-PCR analysis of 14 cases of myxoid/round cell liposarcomas. Ultrastruct Pathol 2003, 27:217-226. 10.1080/01913120309917, 12907366.
    • (2003) Ultrastruct Pathol , vol.27 , pp. 217-226
    • Huang, H.Y.1    Antonescu, C.R.2
  • 36
    • 33845768987 scopus 로고    scopus 로고
    • Integrating cell-signalling pathways with NF-kappaB and IKK function
    • 10.1038/nrm2083, 17183360
    • Perkins ND. Integrating cell-signalling pathways with NF-kappaB and IKK function. Nat Rev Mol Cell Biol 2007, 8:49-62. 10.1038/nrm2083, 17183360.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 49-62
    • Perkins, N.D.1
  • 37
    • 0037112514 scopus 로고    scopus 로고
    • Protein kinase CK2 promotes aberrant activation of nuclear factor-kappaB, transformed phenotype, and survival of breast cancer cells
    • Romieu-Mourez R, Landesman-Bollag E, Seldin DC, Sonenshein GE. Protein kinase CK2 promotes aberrant activation of nuclear factor-kappaB, transformed phenotype, and survival of breast cancer cells. Cancer Res 2002, 62:6770-6778.
    • (2002) Cancer Res , vol.62 , pp. 6770-6778
    • Romieu-Mourez, R.1    Landesman-Bollag, E.2    Seldin, D.C.3    Sonenshein, G.E.4
  • 39
    • 0035918291 scopus 로고    scopus 로고
    • Involvement of the pro-oncoprotein TLS (translocated in liposarcoma) in nuclear factor-kappa B p65-mediated transcription as a coactivator
    • 10.1074/jbc.M011176200, 11278855
    • Uranishi H, Tetsuka T, Yamashita M, Asamitsu K, Shimizu M, Itoh M, Okamoto T. Involvement of the pro-oncoprotein TLS (translocated in liposarcoma) in nuclear factor-kappa B p65-mediated transcription as a coactivator. J Biol Chem 2001, 276:13395-13401. 10.1074/jbc.M011176200, 11278855.
    • (2001) J Biol Chem , vol.276 , pp. 13395-13401
    • Uranishi, H.1    Tetsuka, T.2    Yamashita, M.3    Asamitsu, K.4    Shimizu, M.5    Itoh, M.6    Okamoto, T.7
  • 40
    • 0030914691 scopus 로고    scopus 로고
    • CREB-binding protein/p300 are transcriptional coactivators of p65
    • 10.1073/pnas.94.7.2927, 20299, 9096323
    • Gerritsen ME, Williams AJ, Neish AS, Moore S, Shi Y, Collins T. CREB-binding protein/p300 are transcriptional coactivators of p65. Proc Natl Acad Sci USA 1997, 94:2927-2932. 10.1073/pnas.94.7.2927, 20299, 9096323.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 2927-2932
    • Gerritsen, M.E.1    Williams, A.J.2    Neish, A.S.3    Moore, S.4    Shi, Y.5    Collins, T.6
  • 41
    • 0030614504 scopus 로고    scopus 로고
    • Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator
    • 10.1126/science.275.5299.523, 8999795
    • Perkins ND, Felzien LK, Betts JC, Leung K, Beach DH, Nabel GJ. Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator. Science 1997, 275:523-527. 10.1126/science.275.5299.523, 8999795.
    • (1997) Science , vol.275 , pp. 523-527
    • Perkins, N.D.1    Felzien, L.K.2    Betts, J.C.3    Leung, K.4    Beach, D.H.5    Nabel, G.J.6
  • 42
    • 0032034216 scopus 로고    scopus 로고
    • A requirement for NF-kappaB activation in Bcr-Abl-mediated transformation
    • 10.1101/gad.12.7.968, 316671, 9531535
    • Reuther JY, Reuther GW, Cortez D, Pendergast AM, Baldwin AS. A requirement for NF-kappaB activation in Bcr-Abl-mediated transformation. Genes Dev 1998, 12:968-981. 10.1101/gad.12.7.968, 316671, 9531535.
    • (1998) Genes Dev , vol.12 , pp. 968-981
    • Reuther, J.Y.1    Reuther, G.W.2    Cortez, D.3    Pendergast, A.M.4    Baldwin, A.S.5
  • 43
    • 38349116517 scopus 로고    scopus 로고
    • Too much of a good thing: the role of protein kinase CK2 in tumorigenesis and prospects for therapeutic inhibition of CK2
    • Duncan JS, Litchfield DW. Too much of a good thing: the role of protein kinase CK2 in tumorigenesis and prospects for therapeutic inhibition of CK2. Biochim Biophys Acta 2008, 1784:33-47.
    • (2008) Biochim Biophys Acta , vol.1784 , pp. 33-47
    • Duncan, J.S.1    Litchfield, D.W.2
  • 44
    • 8444220527 scopus 로고    scopus 로고
    • Molecular mechanisms of caspase regulation during apoptosis
    • 10.1038/nrm1496, 15520809
    • Riedl SJ, Shi Y. Molecular mechanisms of caspase regulation during apoptosis. Nat Rev Mol Cell Biol 2004, 5:897-907. 10.1038/nrm1496, 15520809.
    • (2004) Nat Rev Mol Cell Biol , vol.5 , pp. 897-907
    • Riedl, S.J.1    Shi, Y.2
  • 45
    • 0034641918 scopus 로고    scopus 로고
    • The biochemistry of apoptosis
    • 10.1038/35037710, 11048727
    • Hengartner MO. The biochemistry of apoptosis. Nature 2000, 407:770-776. 10.1038/35037710, 11048727.
    • (2000) Nature , vol.407 , pp. 770-776
    • Hengartner, M.O.1
  • 47
    • 0024040125 scopus 로고
    • The CD4 receptor is complexed in detergent lysates to a protein-tyrosine kinase (pp58) from human T lymphocytes
    • 10.1073/pnas.85.14.5190, 281714, 2455897
    • Rudd CE, Trevillyan JM, Dasgupta JD, Wong LL, Schlossman SF. The CD4 receptor is complexed in detergent lysates to a protein-tyrosine kinase (pp58) from human T lymphocytes. Proc Natl Acad Sci USA 1988, 85:5190-5194. 10.1073/pnas.85.14.5190, 281714, 2455897.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 5190-5194
    • Rudd, C.E.1    Trevillyan, J.M.2    Dasgupta, J.D.3    Wong, L.L.4    Schlossman, S.F.5
  • 49
    • 68349160285 scopus 로고    scopus 로고
    • Validation of immature adipogenic status and identification of prognostic biomarkers in myxoid liposarcoma using tissue microarrays
    • 10.1016/j.humpath.2009.01.011, 19368956
    • Cheng H, Dodge J, Mehl E, Liu S, Poulin N, van de RM, Nielsen TO. Validation of immature adipogenic status and identification of prognostic biomarkers in myxoid liposarcoma using tissue microarrays. Hum Pathol 2009, 40:1244-1251. 10.1016/j.humpath.2009.01.011, 19368956.
    • (2009) Hum Pathol , vol.40 , pp. 1244-1251
    • Cheng, H.1    Dodge, J.2    Mehl, E.3    Liu, S.4    Poulin, N.5    van de, R.M.6    Nielsen, T.O.7
  • 50
    • 65949102791 scopus 로고    scopus 로고
    • Synergistic activity of the SRC family kinase inhibitor dasatinib and oxaliplatin in colon carcinoma cells is mediated by oxidative stress
    • 10.1158/0008-5472.CAN-08-2246, 2709758, 19383922
    • Kopetz S, Lesslie DP, Dallas NA, Park SI, Johnson M, Parikh NU, Kim MP, Abbruzzese JL, Ellis LM, Chandra J, Gallick GE. Synergistic activity of the SRC family kinase inhibitor dasatinib and oxaliplatin in colon carcinoma cells is mediated by oxidative stress. Cancer Res 2009, 69:3842-3849. 10.1158/0008-5472.CAN-08-2246, 2709758, 19383922.
    • (2009) Cancer Res , vol.69 , pp. 3842-3849
    • Kopetz, S.1    Lesslie, D.P.2    Dallas, N.A.3    Park, S.I.4    Johnson, M.5    Parikh, N.U.6    Kim, M.P.7    Abbruzzese, J.L.8    Ellis, L.M.9    Chandra, J.10    Gallick, G.E.11
  • 52
    • 33748794547 scopus 로고    scopus 로고
    • Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies
    • 10.1124/pr.58.3.10, 16968952
    • Chou TC. Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies. Pharmacol Rev 2006, 58:621-681. 10.1124/pr.58.3.10, 16968952.
    • (2006) Pharmacol Rev , vol.58 , pp. 621-681
    • Chou, T.C.1
  • 53
    • 0344069652 scopus 로고    scopus 로고
    • Identification of genes differentially expressed in TLS-CHOP carrying myxoid liposarcomas
    • 10.1002/(SICI)1097-0215(19990924)83:1<30::AID-IJC6>3.0.CO;2-4, 10449603
    • Thelin-Jarnum S, Lassen C, Panagopoulos I, Mandahl N, Aman P. Identification of genes differentially expressed in TLS-CHOP carrying myxoid liposarcomas. Int J Cancer 1999, 83:30-33. 10.1002/(SICI)1097-0215(19990924)83:1<30::AID-IJC6>3.0.CO;2-4, 10449603.
    • (1999) Int J Cancer , vol.83 , pp. 30-33
    • Thelin-Jarnum, S.1    Lassen, C.2    Panagopoulos, I.3    Mandahl, N.4    Aman, P.5
  • 55
    • 33244498017 scopus 로고    scopus 로고
    • Local recurrence of myxofibrosarcoma is associated with increase in tumour grade and cytogenetic aberrations, suggesting a multistep tumour progression model
    • 10.1038/modpathol.3800550, 16415793
    • Willems SM, Debiec-Rychter M, Szuhai K, Hogendoorn PCW, Sciot R. Local recurrence of myxofibrosarcoma is associated with increase in tumour grade and cytogenetic aberrations, suggesting a multistep tumour progression model. Mod Pathol 2006, 19:407-416. 10.1038/modpathol.3800550, 16415793.
    • (2006) Mod Pathol , vol.19 , pp. 407-416
    • Willems, S.M.1    Debiec-Rychter, M.2    Szuhai, K.3    Hogendoorn, P.C.W.4    Sciot, R.5
  • 57
    • 33846924098 scopus 로고    scopus 로고
    • COBRA: combined binary ratio labeling of nucleic-acid probes for multi-color fluorescence in situ hybridization karyotyping
    • 10.1038/nprot.2006.41, 17406243
    • Szuhai K, Tanke HJ. COBRA: combined binary ratio labeling of nucleic-acid probes for multi-color fluorescence in situ hybridization karyotyping. Nat Protoc 2006, 1:264-275. 10.1038/nprot.2006.41, 17406243.
    • (2006) Nat Protoc , vol.1 , pp. 264-275
    • Szuhai, K.1    Tanke, H.J.2
  • 59
    • 39449084394 scopus 로고    scopus 로고
    • Cyclooxygenase-2 inhibition inhibits c-Met kinase activity and Wnt activity in colon cancer
    • 10.1158/0008-5472.CAN-07-5172, 18281498
    • Tuynman JB, Vermeulen L, Boon EM, Kemper K, Zwinderman AH, Peppelenbosch MP, Richel DJ. Cyclooxygenase-2 inhibition inhibits c-Met kinase activity and Wnt activity in colon cancer. Cancer Res 2008, 68:1213-1220. 10.1158/0008-5472.CAN-07-5172, 18281498.
    • (2008) Cancer Res , vol.68 , pp. 1213-1220
    • Tuynman, J.B.1    Vermeulen, L.2    Boon, E.M.3    Kemper, K.4    Zwinderman, A.H.5    Peppelenbosch, M.P.6    Richel, D.J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.