Expression of kidney injury molecule-1 in rat model of acute kidney injury induced by gentamycin

Chinese Journal of Biologicals

Volumn 23, Issue 7, 2010, Pages 700-703

  Shi, Yan ^a   Wang, Lu Fei ^b   Luo, Ping ^b   Sun, Bo ^b   Li, Xiang Jun ^b   Dong, De Lu ^b   Ren, Li Qun ^b  

^a JILIN UNIVERSITY   (China)

^b NONE

Author keywords

Acute kidney injury; Gentamycins (GMs); Kidney injury molecule 1 (KIM 1)

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; GENTAMICIN; KIDNEY INJURY MOLECULE 1; MESSENGER RNA; VIMENTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD; CONTROLLED STUDY; KIDNEY INJURY; KIDNEY PARENCHYMA; NONHUMAN; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RAT; UPREGULATION; URINE;

RATTUS;

EID: 77956844277     PISSN: 10045503     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Ozbek E, Cekmen M, Ilbey YO, et al. Atorvastatin prevents gentamicin-induced renal damage in rats through the inhibition of p38-MAPK and NF-kappaB pathways [J]. Ren Fail, 2009, 31 (5): 382-392.
2. Antoine DJ, Srivastava A, Pirmohamed M, et al. Statins inhibit aminoglycoside accumulation and cytotoxicity to renal proximal tubule cells [J]. Biochem Pharmacol, 2010, 79 (4): 647-654.
3. Vaidya VS, Ramirez V, Ichimura T, et al. Urinary kidney injury molecule-1: a sensitive quantitative biomarker for early detection of kidney tubular injury [J]. Am J Physiol Renal Physiol, 2006, 290 (2): F517-F529.
4. Lerner SA, Schmitt BA, Seligsohn R, et al. Comparative study of ototoxicity and nephrotoxicity in patients randomly assigned to treatment with amikacin or gentamicin [J]. Am J Med, 1986, 80 (6B): 98-104.
5. Van Timmeren MM, Bakker SJ, Vaidya VS, et al. Tubular kidney injury molecule-1 in protein-overload nephropathy [J]. Am J Physiol Renal Physiol, 2006, 291 (2): F456-F464.
6. Nogare AL, Joelsons G, Pedroso JA, et al. Quantitative analyses of kidney injury molecule-1 messenger RNA in kidney transplant recipients with graft dysfunction [J] . Transplant Proc, 2010, 42 (2): 473-474.