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Volumn 84, Issue 19, 2010, Pages 9932-9946

Alterations in the immunogenic properties of soluble trimeric human immunodeficiency virus type 1 envelope proteins induced by deletion or heterologous substitutions of the V1 loop

Author keywords

[No Author keywords available]

Indexed keywords

CROSS REACTING ANTIBODY; GLYCOPROTEIN E1; GLYCOPROTEIN GP 140; NEUTRALIZING ANTIBODY; EPITOPE; GP140 ENVELOPE PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; HUMAN IMMUNODEFICIENCY VIRUS ANTIGEN; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; MONOCLONAL ANTIBODY; PRIMER DNA; RECOMBINANT PROTEIN; VIRUS DNA; VIRUS ENVELOPE PROTEIN;

EID: 77956839028     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00868-10     Document Type: Article
Times cited : (13)

References (61)
  • 2
    • 33947590277 scopus 로고    scopus 로고
    • A comparative immunogenicity study in rabbits of disulfide-stabilized, proteolytically cleaved, soluble trimeric human immunodeficiency virus type 1 gp140, trimeric cleavage-defective gp140 and monomeric gp120
    • DOI 10.1016/j.virol.2006.10.032, PII S0042682206007884
    • Beddows, S., M. Franti, A. Dey, M. Kirschner, S. Iyer, D. Fisch, T. Ketas, E. Yuste, R. Desrosiers, P. Klasse, P. Maddon, W. Olson, and J. Moore. 2007. A comparative immunogenicity study in rabbits of disulfide-stabilized, proteolytically cleaved, soluble trimeric human immunodeficiency virus type 1 gp140, trimeric cleavage-defective gp140 and monomeric gp120. Virology 360:329-340. (Pubitemid 46482615)
    • (2007) Virology , vol.360 , Issue.2 , pp. 329-340
    • Beddows, S.1    Franti, M.2    Dey, A.K.3    Kirschner, M.4    Iyer, S.P.N.5    Fisch, D.C.6    Ketas, T.7    Yuste, E.8    Desrosiers, R.C.9    Klasse, P.J.10    Maddon, P.J.11    Olson, W.C.12    Moore, J.P.13
  • 3
    • 21644445378 scopus 로고    scopus 로고
    • Evaluating the immunogenicity of a disulfide-stabilized, cleaved, trimeric form of the envelope glycoprotein complex of human immunodeficiency virus type 1
    • Beddows, S., N. Schulke, M. Kirschner, K. Barnes, M. Franti, E. Michael, T. Ketas, R. W. Sanders, P. J. Maddon, W. C. Olson, and J. P. Moore. 2005. Evaluating the immunogenicity of a disulfide-stabilized, cleaved, trimeric form of the envelope glycoprotein complex of human immunodeficiency virus type 1. J. Virol. 79:8812-8827.
    • (2005) J. Virol. , vol.79 , pp. 8812-8827
    • Beddows, S.1    Schulke, N.2    Kirschner, M.3    Barnes, K.4    Franti, M.5    Michael, E.6    Ketas, T.7    Sanders, R.W.8    Maddon, P.J.9    Olson, W.C.10    Moore, J.P.11
  • 4
    • 69549086342 scopus 로고    scopus 로고
    • Specificities of broadly neutralizing anti-HIV-1 sera
    • Binley, J. 2009. Specificities of broadly neutralizing anti-HIV-1 sera. Curr. Opin. HIV AIDS 4:364-372.
    • (2009) Curr. Opin. HIV AIDS , vol.4 , pp. 364-372
    • Binley, J.1
  • 5
    • 0033985999 scopus 로고    scopus 로고
    • A recombinant human immunodeficiency virus type 1 envelope glycoprotein complex stabilized by an intermolecular disulfide bond between the gp120 and gp41 subunits is an antigenic mimic of the trimeric virion-associated structure
    • DOI 10.1128/JVI.74.2.627-643.2000
    • Binley, J., R. Sanders, B. Clas, N. Schuelke, A. Master, Y. Guo, F. Kajumo, D. Anselma, P. Maddon, W. Olson, and J. Moore. 2000. A recombinant human immunodeficiency virus type 1 envelope glycoprotein complex stabilized by an intermolecular disulfide bond between the gp120 and gp41 subunits is an antigenic mimic of the trimeric virion-associated structure. J. Virol. 74:627-643. (Pubitemid 30036198)
    • (2000) Journal of Virology , vol.74 , Issue.2 , pp. 627-643
    • Binley, J.M.1    Sanders, R.W.2    Clas, B.3    Schuelke, N.4    Master, A.5    Guo, Y.6    Kajumo, F.7    Anselma, D.J.8    Maddon, P.J.9    Olson, W.C.10    Moore, J.P.11
  • 10
    • 0031010076 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 and 2 envelope glycoproteins oligomerize through conserved sequences
    • Center, R., B. Kemp, and P. Poumbourios. 1997. Human immunodeficiency virus type 1 and 2 envelope glycoproteins oligomerize through conserved sequences. J. Virol. 71:5706-5711.
    • (1997) J. Virol. , vol.71 , pp. 5706-5711
    • Center, R.1    Kemp, B.2    Poumbourios, P.3
  • 11
    • 0025866787 scopus 로고
    • Effect of intron a from human cytomegalovirus (Towne) immediate-early gene on heterologous expression in mammalian cells
    • Chapman, B. S., R. M. Thayer, K. A. Vincent, and N. L. Haigwood. 1991. Effect of intron A from human cytomegalovirus (Towne) immediate-early gene on heterologous expression in mammalian cells. Nucleic Acids Res. 19:3979-3986.
    • (1991) Nucleic Acids Res. , vol.19 , pp. 3979-3986
    • Chapman, B.S.1    Thayer, R.M.2    Vincent, K.A.3    Haigwood, N.L.4
  • 12
    • 37848999666 scopus 로고    scopus 로고
    • The first hypervariable region of the gp120 Env glycoprotein defines the neutralizing susceptibility of heterologous human immunodeficiency virus type 1 isolates to neutralizing antibodies elicited by the SF162 gp140 immunogen
    • Ching, L. K., G. Vlachogiannis, K. A. Bosch, and L. Stamatatos. 2008. The first hypervariable region of the gp120 Env glycoprotein defines the neutralizing susceptibility of heterologous human immunodeficiency virus type 1 isolates to neutralizing antibodies elicited by the SF162 gp140 immunogen. J. Virol. 82:949-956.
    • (2008) J. Virol. , vol.82 , pp. 949-956
    • Ching, L.K.1    Vlachogiannis, G.2    Bosch, K.A.3    Stamatatos, L.4
  • 17
    • 33748650781 scopus 로고    scopus 로고
    • Antibody responses elicited in macaques immunized with human immunodeficiency virus type 1 (HIV-1) SF162-derived gp140 envelope immunogens: Comparison with those elicited during homologous simian/human immunodeficiency virus SHIVSF162P4 and heterologous HIV-1 infection
    • Derby, N. R., Z. Kraft, E. Kan, E. T. Crooks, S. W. Barnett, I. K. Srivastava, J. M. Binley, and L. Stamatatos. 2006. Antibody responses elicited in macaques immunized with human immunodeficiency virus type 1 (HIV-1) SF162-derived gp140 envelope immunogens: comparison with those elicited during homologous simian/human immunodeficiency virus SHIVSF162P4 and heterologous HIV-1 infection. J. Virol. 80:8745-8762.
    • (2006) J. Virol. , vol.80 , pp. 8745-8762
    • Derby, N.R.1    Kraft, Z.2    Kan, E.3    Crooks, E.T.4    Barnett, S.W.5    Srivastava, I.K.6    Binley, J.M.7    Stamatatos, L.8
  • 18
    • 34249827906 scopus 로고    scopus 로고
    • Characterization of human immunodeficiency virus type 1 monomeric and trimeric gp120 glycoproteins stabilized in the CD4-bound state: Antigenicity, biophysics, and immunogenicity
    • DOI 10.1128/JVI.02500-06
    • Dey, B., M. Pancera, K. Svehla, Y. Shu, S. H. Xiang, J. Vainshtein, Y. Li, J. Sodroski, P. D. Kwong, J. R. Mascola, and R. Wyatt. 2007. Characterization of human immunodeficiency virus type 1 monomeric and trimeric gp120 glycoproteins stabilized in the CD4-bound state: antigenicity, biophysics, and immunogenicity. J. Virol. 81:5579-5593. (Pubitemid 46846998)
    • (2007) Journal of Virology , vol.81 , Issue.11 , pp. 5579-5593
    • Dey, B.1    Pancera, M.2    Svehla, K.3    Shu, Y.4    Xiang, S.-H.5    Vainshtein, J.6    Li, Y.7    Sodroski, J.8    Kwong, P.D.9    Mascola, J.R.10    Wyatt, R.11
  • 20
    • 0026029621 scopus 로고
    • Folding, interaction with GRP78-BiP, assembly, and transport of the human immunodeficiency virus type 1 envelope protein
    • Earl, P., L, B. Moss, and R. W. Doms. 1991. Folding, interaction with GRP78-BiP, assembly, and transport of the human immunodeficiency virus type 1 envelope protein. J. Virol. 65:2047-2055.
    • (1991) J. Virol. , vol.65 , pp. 2047-2055
    • Earl, P.1    Moss, L.B.2    Doms, R.W.3
  • 21
    • 0027183021 scopus 로고
    • Mutational analysis of the assembly domain of the HIV-1 envelope glycoprotein
    • Earl, P., and B. Moss. 1993. Mutational analysis of the assembly domain of the HIV-1 envelope glycoprotein. AIDS Res. Hum. Retroviruses 9:589-594.
    • (1993) AIDS Res. Hum. Retroviruses , vol.9 , pp. 589-594
    • Earl, P.1    Moss, B.2
  • 23
    • 70350320582 scopus 로고    scopus 로고
    • Broad neutralization of human immunodeficiency virus type 1 mediated by plasma antibodies against the gp41 membrane proximal external region
    • Gray, E. S., M. C. Madiga, P. L. Moore, K. Mlisana, S. S. Abdool Karim, J. M. Binley, G. M. Shaw, J. R. Mascola, and L. Morris. 2009. Broad neutralization of human immunodeficiency virus type 1 mediated by plasma antibodies against the gp41 membrane proximal external region. J. Virol. 83:11265-11274.
    • (2009) J. Virol. , vol.83 , pp. 11265-11274
    • Gray, E.S.1    Madiga, M.C.2    Moore, P.L.3    Mlisana, K.4    Abdool Karim, S.S.5    Binley, J.M.6    Shaw, G.M.7    Mascola, J.R.8    Morris, L.9
  • 26
    • 9944264023 scopus 로고    scopus 로고
    • Analysis of the neutralizing antibody response elicited in rabbits by repeated inoculation with trimeric HIV-1 envelope glycoproteins
    • DOI 10.1016/j.virol.2004.09.022, PII S0042682204006245
    • Grundner, C., Y. Li, M. Louder, J. Mascola, X. Yang, J. Sodroski, and R. Wyatt. 2005. Analysis of the neutralizing antibody response elicited in rabbits by repeated inoculation with trimeric HIV-1 envelope glycoproteins. Virology 331:33-46. (Pubitemid 39593631)
    • (2005) Virology , vol.331 , Issue.1 , pp. 33-46
    • Grundner, C.1    Li, Y.2    Louder, M.3    Mascola, J.4    Yang, X.5    Sodroski, J.6    Wyatt, R.7
  • 27
    • 0141458878 scopus 로고    scopus 로고
    • Assorted mutations in the envelope gene of simian immunodeficiency virus lead to loss of neutralization resistance against antibodies representing a broad spectrum of specificities
    • Johnson, W. E., H. Sanford, L. Schwall, D. R. Burton, P. W. Parren, J. E. Robinson, and R. C. Desrosiers. 2003. Assorted mutations in the envelope gene of simian immunodeficiency virus lead to loss of neutralization resistance against antibodies representing a broad spectrum of specificities. J. Virol. 77:9993-10003.
    • (2003) J. Virol. , vol.77 , pp. 9993-10003
    • Johnson, W.E.1    Sanford, H.2    Schwall, L.3    Burton, D.R.4    Parren, P.W.5    Robinson, J.E.6    Desrosiers, R.C.7
  • 28
    • 44949262146 scopus 로고    scopus 로고
    • Characterization of neutralizing antibody responses elicited by clade a envelope immunogens derived from early transmitted viruses
    • Kraft, Z., K. Strouss, W. F. Sutton, B. Cleveland, F. Y. Tso, P. Polacino, J. Overbaugh, S. L. Hu, and L. Stamatatos. 2008. Characterization of neutralizing antibody responses elicited by clade A envelope immunogens derived from early transmitted viruses. J. Virol. 82:5912-5921.
    • (2008) J. Virol. , vol.82 , pp. 5912-5921
    • Kraft, Z.1    Strouss, K.2    Sutton, W.F.3    Cleveland, B.4    Tso, F.Y.5    Polacino, P.6    Overbaugh, J.7    Hu, S.L.8    Stamatatos, L.9
  • 30
    • 31144451337 scopus 로고    scopus 로고
    • Characterization of antibody responses elicited by human immunodeficiency virus type 1 primary isolate trimeric and monomeric envelope glycoproteins in selected adjuvants
    • Li, Y., K. Svehla, N. Mathy, G. Voss, J. Mascola, and R. Wyatt. 2006. Characterization of antibody responses elicited by human immunodeficiency virus type 1 primary isolate trimeric and monomeric envelope glycoproteins in selected adjuvants. J. Virol. 80:1414-1426.
    • (2006) J. Virol. , vol.80 , pp. 1414-1426
    • Li, Y.1    Svehla, K.2    Mathy, N.3    Voss, G.4    Mascola, J.5    Wyatt, R.6
  • 31
    • 1842562419 scopus 로고    scopus 로고
    • N-Linked Glycosylation of the V3 Loop and the Immunologically Silent Face of gp120 Protects Human Immunodeficiency Virus Type 1 SF162 from Neutralization by Anti-gp120 and Anti-gp41 Antibodies
    • DOI 10.1128/JVI.78.7.3279-3295.2004
    • McCaffrey, R., C. Saunders, M. Hensel, and L. Stamatatos. 2004. N-linked glycosylation of the V3 loop and the immunologically silent face of gp120 protects human immunodeficiency virus type 1 SF162 from neutralization by anti-gp120 and anti-gp41 antibodies. J. Virol. 78:3279-3295. (Pubitemid 38568268)
    • (2004) Journal of Virology , vol.78 , Issue.7 , pp. 3279-3295
    • McCaffrey, R.A.1    Saunders, C.2    Hensel, M.3    Stamatatos, L.4
  • 32
    • 60349089294 scopus 로고    scopus 로고
    • Measuring HIV neutralization in a luciferase reporter gene assay
    • Montefiori, D. 2009. Measuring HIV neutralization in a luciferase reporter gene assay. Methods Mol. Biol. 485:395-405.
    • (2009) Methods Mol. Biol. , vol.485 , pp. 395-405
    • Montefiori, D.1
  • 34
    • 22544471847 scopus 로고    scopus 로고
    • Soluble mimetics of human immunodeficiency virus type 1 viral spikes produced by replacement of the native trimerization domain with a heterologous trimerization motif: Characterization and ligand binding analysis
    • Pancera, M., J. Lebowitz, A. Schon, P. Zhu, E. Freire, P. D. Kwong, K. H. Roux, J. Sodroski, and R. Wyatt. 2005. Soluble mimetics of human immunodeficiency virus type 1 viral spikes produced by replacement of the native trimerization domain with a heterologous trimerization motif: characterization and ligand binding analysis. J. Virol. 79:9954-9969.
    • (2005) J. Virol. , vol.79 , pp. 9954-9969
    • Pancera, M.1    Lebowitz, J.2    Schon, A.3    Zhu, P.4    Freire, E.5    Kwong, P.D.6    Roux, K.H.7    Sodroski, J.8    Wyatt, R.9
  • 35
    • 0033129374 scopus 로고    scopus 로고
    • CD4 receptor-dependent entry of human immunodeficiency virus type-1 env-pseudotypes into CCR5-, CCR3-, and CXCR4-expressing human alveolar macrophages is preferentially mediated by the CCR5 coreceptor
    • Park, I., H. Koziel, W. Hatch, X. Li, B. Du, and J. Groopman. 1999. CD4 receptor-dependent entry of human immunodeficiency virus type-1 env-pseudotypes into CCR5-, CCR3-, and CXCR4-expressing human alveolar macrophages is preferentially mediated by the CCR5 coreceptor. Am. J. Respir. Cell Mol. Biol. 20:864-871.
    • (1999) Am. J. Respir. Cell Mol. Biol. , vol.20 , pp. 864-871
    • Park, I.1    Koziel, H.2    Hatch, W.3    Li, X.4    Du, B.5    Groopman, J.6
  • 36
    • 0031001740 scopus 로고    scopus 로고
    • Role of the amino-terminal extracellular domain of CXCR-4 in human immunodeficiency virus type 1 entry
    • DOI 10.1006/viro.1997.8506
    • Picard, L., D. Wilkinson, A. McKnight, P. Gray, J. Hoxie, P. Clapham, and R. Weiss. 1997. Role of the amino-terminal extracellular domain of CXCR-4 in human immunodeficiency virus type 1 entry. Virology 231:105-111. (Pubitemid 27238767)
    • (1997) Virology , vol.231 , Issue.1 , pp. 105-111
    • Picard, L.1    Wilkinson, D.A.2    McKnight, A.3    Gray, P.W.4    Hoxie, J.A.5    Clapham, P.R.6    Weiss, R.A.7
  • 37
    • 77951480441 scopus 로고    scopus 로고
    • Anti-gp41 antibodies cloned from HIV-infected patients with broadly neutralizing serologic activity
    • Pietzsch, J., J. F. Scheid, H. Mouquet, M. S. Seaman, C. C. Broder, and M. C. Nussenzweig. 2010. Anti-gp41 antibodies cloned from HIV-infected patients with broadly neutralizing serologic activity. J. Virol. 84:5032-5042.
    • (2010) J. Virol. , vol.84 , pp. 5032-5042
    • Pietzsch, J.1    Scheid, J.F.2    Mouquet, H.3    Seaman, M.S.4    Broder, C.C.5    Nussenzweig, M.C.6
  • 39
    • 77949411309 scopus 로고    scopus 로고
    • Quaternary epitope specificities of anti-HIV-1 neutralizing antibodies generated in rhesus macaques infected by the simian/human immunodeficiency virus SHIVSF162P4
    • Robinson, J. E., K. Franco, D. H. Elliott, M. J. Maher, A. Reyna, D. C. Montefiori, S. Zolla-Pazner, M. K. Gorny, Z. Kraft, and L. Stamatatos. 2010. Quaternary epitope specificities of anti-HIV-1 neutralizing antibodies generated in rhesus macaques infected by the simian/human immunodeficiency virus SHIVSF162P4. J. Virol. 84:3443-3453.
    • (2010) J. Virol. , vol.84 , pp. 3443-3453
    • Robinson, J.E.1    Franco, K.2    Elliott, D.H.3    Maher, M.J.4    Reyna, A.5    Montefiori, D.C.6    Zolla-Pazner, S.7    Gorny, M.K.8    Kraft, Z.9    Stamatatos, L.10
  • 41
    • 0036637385 scopus 로고    scopus 로고
    • The mannose-dependent epitope for neutralizing antibody 2G12 on human immunodeficiency virus type 1 glycoprotein gp120
    • Sanders, R. W., M. Venturi, L. Schiffner, R. Kalyanaraman, H. Katinger, K. O. Lloyd, P. D. Kwong, and J. P. Moore. 2002. The mannose-dependent epitope for neutralizing antibody 2G12 on human immunodeficiency virus type 1 glycoprotein gp120. J. Virol. 76:7293-7305.
    • (2002) J. Virol. , vol.76 , pp. 7293-7305
    • Sanders, R.W.1    Venturi, M.2    Schiffner, L.3    Kalyanaraman, R.4    Katinger, H.5    Lloyd, K.O.6    Kwong, P.D.7    Moore, J.P.8
  • 43
    • 21644446614 scopus 로고    scopus 로고
    • The V1, V2, and V3 regions of the human immunodeficiency virus type 1 envelope differentially affect the viral phenotype in an isolate-dependent manner
    • Saunders, C. J., R. A. McCaffrey, I. Zharkikh, Z. Kraft, S. E. Malenbaum, B. Burke, C. Cheng-Mayer, and L. Stamatatos. 2005. The V1, V2, and V3 regions of the human immunodeficiency virus type 1 envelope differentially affect the viral phenotype in an isolate-dependent manner. J. Virol. 79:9069-9080.
    • (2005) J. Virol. , vol.79 , pp. 9069-9080
    • Saunders, C.J.1    McCaffrey, R.A.2    Zharkikh, I.3    Kraft, Z.4    Malenbaum, S.E.5    Burke, B.6    Cheng-Mayer, C.7    Stamatatos, L.8
  • 44
    • 18244422922 scopus 로고    scopus 로고
    • The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1→2 mannose residues on the outer face of gp120
    • Scanlan, C. N., R. Pantophlet, M. R. Wormald, E. Ollmann Saphire, R. Stanfield, I. A. Wilson, H. Katinger, R. A. Dwek, P. M. Rudd, and D. R. Burton. 2002. The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1→2 mannose residues on the outer face of gp120. J. Virol. 76:7306-7321.
    • (2002) J. Virol. , vol.76 , pp. 7306-7321
    • Scanlan, C.N.1    Pantophlet, R.2    Wormald, M.R.3    Ollmann Saphire, E.4    Stanfield, R.5    Wilson, I.A.6    Katinger, H.7    Dwek, R.A.8    Rudd, P.M.9    Burton, D.R.10
  • 46
    • 70649096029 scopus 로고    scopus 로고
    • Improving the expression of recombinant soluble HIV envelope glycoproteins using pseudo-stable transient transfection
    • Sellhorn, G., Z. Caldwell, C. Mineart, and L. Stamatatos. 2009. Improving the expression of recombinant soluble HIV envelope glycoproteins using pseudo-stable transient transfection. Vaccine 28:430-436.
    • (2009) Vaccine , vol.28 , pp. 430-436
    • Sellhorn, G.1    Caldwell, Z.2    Mineart, C.3    Stamatatos, L.4
  • 47
    • 0037348281 scopus 로고    scopus 로고
    • Effects of HIV type 1 envelope glycoprotein proteolytic processing on antigenicity. AIDS Res. Hum
    • Si, Z., N. Phan, E. Kiprilov, and J. Sodroski. 2003. Effects of HIV type 1 envelope glycoprotein proteolytic processing on antigenicity. AIDS Res. Hum. Retroviruses 19:217-226.
    • (2003) Retroviruses , vol.19 , pp. 217-226
    • Si, Z.1    Phan, N.2    Kiprilov, E.3    Sodroski, J.4
  • 48
    • 10344266976 scopus 로고    scopus 로고
    • Primary, syncytium-inducing human immunodeficiency virus type 1 isolates are dual-tropic and most can use either Lestr or CCR5 as coreceptors for virus entry
    • Simmons, G., D. Wilkinson, J. Reeves, M. Dittmar, S. Beddows, J. Weber, G. Carnegie, U. Desselberger, P. Gray, R. Weiss, and P. Clapham. 1996. Primary, syncytium-inducing human immunodeficiency virus type 1 isolates are dual-tropic and most can use either Lestr or CCR5 as coreceptors for virus entry. J. Virol. 70:8355-8360.
    • (1996) J. Virol. , vol.70 , pp. 8355-8360
    • Simmons, G.1    Wilkinson, D.2    Reeves, J.3    Dittmar, M.4    Beddows, S.5    Weber, J.6    Carnegie, G.7    Desselberger, U.8    Gray, P.9    Weiss, R.10    Clapham, P.11
  • 49
    • 0141788494 scopus 로고    scopus 로고
    • Purification, characterization, and immunogenicity of a soluble trimeric envelope protein containing a partial deletion of the V2 loop derived from SF162, an R5-tropic human immunodeficiency virus type 1 isolate
    • Srivastava, I. K., L. Stamatatos, E. Kan, M. Vajdy, Y. Lian, S. Hilt, L. Martin, C. Vita, P. Zhu, K. H. Roux, L. Vojtech, C. M. D., J. Donnelly, J. B. Ulmer, and S. W. Barnett. 2003. Purification, characterization, and immunogenicity of a soluble trimeric envelope protein containing a partial deletion of the V2 loop derived from SF162, an R5-tropic human immunodeficiency virus type 1 isolate. J. Virol. 77:11244-11259.
    • (2003) J. Virol. , vol.77 , pp. 11244-11259
    • Srivastava, I.K.1    Stamatatos, L.2    Kan, E.3    Vajdy, M.4    Lian, Y.5    Hilt, S.6    Martin, L.7    Vita, C.8    Zhu, P.9    Roux, K.H.10    Vojtech, L.11    D, C.M.12    Donnelly, J.13    Ulmer, J.B.14    Barnett, S.W.15
  • 51
    • 0031666180 scopus 로고    scopus 로고
    • An envelope modification that renders a primary, neutralization- Resistant clade B human immunodeficiency virus type 1 isolate highly susceptible to neutralization by sera from other clades
    • Stamatatos, L., and C. Cheng-Mayer. 1998. An envelope modification that renders a primary, neutralization-resistant clade B human immunodeficiency virus type 1 isolate highly susceptible to neutralization by sera from other clades. J. Virol. 72:7840-7845. (Pubitemid 28421774)
    • (1998) Journal of Virology , vol.72 , Issue.10 , pp. 7840-7845
    • Stamatatos, L.1    Cheng-Mayer, C.2
  • 52
    • 0034235058 scopus 로고    scopus 로고
    • Generation and structural analysis of soluble oligomeric envelope proteins derived from neutralization-resistant and neutralization-susceptible primary HIV-1 isolates
    • Stamatatos, L., M. Lim, and C. Cheng-Mayer. 2000. Generation and structural analysis of soluble oligomeric envelope proteins derived from neutralization-resistant and neutralization-susceptible primary HIV-1 isolates. AIDS Res. Hum. Retroviruses 16:981-994.
    • (2000) AIDS Res. Hum. Retroviruses , vol.16 , pp. 981-994
    • Stamatatos, L.1    Lim, M.2    Cheng-Mayer, C.3
  • 53
    • 0032169683 scopus 로고    scopus 로고
    • Effect of major deletions in the V1 and V2 loops of a macrophage-tropic HIV-1 isolate on viral envelope structure, cell-entry and replication
    • Stamatatos, L., M. Wiskerchen, and C. Cheng-Mayer. 1998. Effect of major deletions in the V1 and V2 loops of a macrophage-tropic HIV-1 isolate on viral envelope structure, cell-entry and replication. AIDS Res. Hum. Retroviruses 14:1129-1139.
    • (1998) AIDS Res. Hum. Retroviruses , vol.14 , pp. 1129-1139
    • Stamatatos, L.1    Wiskerchen, M.2    Cheng-Mayer, C.3
  • 54
    • 0025266354 scopus 로고
    • Intracellular processing of the gp160 HIV-1 envelope precursor. Endoproteolytic cleavage occurs in a cis or medial compartment of the Golgi complex
    • Stein, B., and E. Engleman. 1990. Intracellular processing of the gp160 HIV-1 envelope precursor. Endoproteolytic cleavage occurs in a cis or medial compartment of the Golgi complex. J. Biol. Chem. 265:2640-2649.
    • (1990) J. Biol. Chem. , vol.265 , pp. 2640-2649
    • Stein, B.1    Engleman, E.2
  • 55
    • 0022328654 scopus 로고
    • Characterization of the polypeptide composition of human factor VIII:C and the nucleotide sequence and expression of the human kidney cDNA
    • Truett, M., R. Blacher, R. Burke, D. Caput, C. Chu, D. Dina, K. Hartog, C. Kuo, F. Masiarz, and J. Merryweather. 1985. Characterization of the polypeptide composition of human factor VIII:C and the nucleotide sequence and expression of the human kidney cDNA. DNA 4:333-349.
    • (1985) DNA , vol.4 , pp. 333-349
    • Truett, M.1    Blacher, R.2    Burke, R.3    Caput, D.4    Chu, C.5    Dina, D.6    Hartog, K.7    Kuo, C.8    Masiarz, F.9    Merryweather, J.10
  • 56
    • 33744470143 scopus 로고    scopus 로고
    • Cross-clade recognition and neutralization by the V3 region from clade C human immunodeficiency virus-1 envelope
    • Wu, L., Z. Y. Yang, L. Xu, B. Welcher, S. Winfrey, Y. Shao, J. R. Mascola, and G. J. Nabel. 2006. Cross-clade recognition and neutralization by the V3 region from clade C human immunodeficiency virus-1 envelope. Vaccine 24:4995-5002.
    • (2006) Vaccine , vol.24 , pp. 4995-5002
    • Wu, L.1    Yang, Z.Y.2    Xu, L.3    Welcher, B.4    Winfrey, S.5    Shao, Y.6    Mascola, J.R.7    Nabel, G.J.8
  • 57
    • 8644270507 scopus 로고    scopus 로고
    • Characterization of the outer domain of the gp120 glycoprotein from human immunodeficiency virus type 1
    • Yang, X., V. Tomov, S. Kurteva, L. Wang, X. Ren, M. K. Gorny, S. Zolla-Pazner, and J. Sodroski. 2004. Characterization of the outer domain of the gp120 glycoprotein from human immunodeficiency virus type 1. J. Virol. 78:12975-12986.
    • (2004) J. Virol. , vol.78 , pp. 12975-12986
    • Yang, X.1    Tomov, V.2    Kurteva, S.3    Wang, L.4    Ren, X.5    Gorny, M.K.6    Zolla-Pazner, S.7    Sodroski, J.8
  • 58
    • 0035155850 scopus 로고    scopus 로고
    • Improved elicitation of neutralizing antibodies against primary human immunodeficiency viruses by soluble stabilized envelope glycoprotein trimers
    • DOI 10.1128/JVI.75.3.1165-1171.2001
    • Yang, X., R. Wyatt, and J. Sodroski. 2001. Improved elicitation of neutralizing antibodies against primary human immunodeficiency viruses by soluble stabilized envelope glycoprotein trimers. J. Virol. 75:1165-1171. (Pubitemid 32094675)
    • (2001) Journal of Virology , vol.75 , Issue.3 , pp. 1165-1171
    • Yang, X.1    Wyatt, R.2    Sodroski, J.3
  • 59
    • 33646744353 scopus 로고    scopus 로고
    • Improving on nature: Focusing the immune response on the V3 loop
    • Humoral immune response against HIV-1
    • Zolla-Pazner, S. 2005. Improving on nature: focusing the immune response on the V3 loop. Hum. Antibodies 14:69-72. (Pubitemid 43748236)
    • (2005) Human Antibodies , vol.14 , Issue.3-4 , pp. 69-72
    • Zolla-Pazner, S.1
  • 60
    • 11144227042 scopus 로고    scopus 로고
    • Anti-human immunodeficiency virus type 1 (HIV-1) antibodies 2F5 and 4E10 require surprisingly few crucial residues in the membrane-proximal external region of glycoprotein gp41 to neutralize HIV-1
    • Zwick, M. B., R. Jensen, S. Church, M. Wang, G. Stiegler, R. Kunert, H. Katinger, and D. R. Burton. 2005. Anti-human immunodeficiency virus type 1 (HIV-1) antibodies 2F5 and 4E10 require surprisingly few crucial residues in the membrane-proximal external region of glycoprotein gp41 to neutralize HIV-1. J. Virol. 79:1252-1261.
    • (2005) J. Virol. , vol.79 , pp. 1252-1261
    • Zwick, M.B.1    Jensen, R.2    Church, S.3    Wang, M.4    Stiegler, G.5    Kunert, R.6    Katinger, H.7    Burton, D.R.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.