Less is not always more: Sugammadex and the risk of under-dosing

European Journal of Anaesthesiology

Volumn 27, Issue 10, 2010, Pages 849-850

  Fuchs Buder, Thomas ^a  

^a UNIVERSITY HOSPITAL OF NANCY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ATROPINE; BUNGAROTOXIN RECEPTOR; ROCURONIUM; SUGAMMADEX;

DOSE RESPONSE; DRUG ANTAGONISM; DRUG MECHANISM; DRUG RECEPTOR BINDING; DRUG UNDERDOSE; ENCAPSULATION; HUMAN; MUSCLE RELAXATION; NEUROMUSCULAR BLOCKING; NEUROMUSCULAR SYNAPSE; NOTE; RECOMMENDED DRUG DOSE;

DOSE-RESPONSE RELATIONSHIP, DRUG; GAMMA-CYCLODEXTRINS; HUMANS; NEUROMUSCULAR BLOCKADE; NEUROMUSCULAR NONDEPOLARIZING AGENTS;

EID: 77956823654     PISSN: 02650215     EISSN: 13652346     Source Type: Journal    
DOI: 10.1097/EJA.0b013e32833dce3a     Document Type: Note

References (6)

1. Mirakhur RK. Sugammadexin clinical practice. Anaesthesia 2009; 64:45-54.
2. Dahl V, Pendeville PE, Hollmann MW, et al Safety and efficacy of sugammadex for the reversal of rocuronium-induced neuromuscular blockade in cardiac patients undergoing noncardiac surgery. Eur J Anaesthesiol 2009; 26:874-884.
3. Petrun AM, Mekis D, Kamenik M. Successful use of rocuronium and sugammadex in a patient with myasthenia. Eur J Anaesthesiol 2010; 27:917-922.
4. Plaud B, Debaene B, Donati F, Marty J. Residual paralysis after emergence from anesthesia. Anesthesiology 2010; 112:1013-1022.
5. Eleveld DJ, Kuizenga K, Proost JH, Wierda JM. A temporary decrease in twitch response during reversal of rocuronium-induced muscle relaxation with a small dose of sugammadex. Anesth Analg 2007; 104: 582-584.
6. Drobnik L, Sparr HJ, Thorn S-E, et al. A randomized simultaneous comparison of acceleromyography with a peripheral nerve stimulator for assessing reversal of rocuronium-induced neuromuscular blockade with sugammadex. Eur J Anaesthesiol 2010; 27:866-873.