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Volumn 151, Issue 1, 2010, Pages 3-15

Development of target-specific treatments in multiple myeloma

Author keywords

bortezomib; lenalidomide; multiple myeloma; tanespimycin; thalidomide

Indexed keywords

1 (1 CYANO 1 METHYLETHYL) 3 METHYL 8 (3 QUINOLINYL)IMIDAZO[4,5 C]QUINOLIN 2(1H,3H) ONE; ARSENIC TRIOXIDE; BORTEZOMIB; CARFILZOMIB; DEXAMETHASONE; GIVINOSTAT; HEAT SHOCK PROTEIN 90; HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; LENALIDOMIDE; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; MELPHALAN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MONOCLONAL ANTIBODY; OBLIMERSEN; PANOBINOSTAT; PERIFOSINE; POMALIDOMIDE; PREDNISONE; PROTEASOME INHIBITOR; PROTEIN BCL 2; PROTEIN KINASE B; TANESPIMYCIN; TELOMERASE; TELOMERASE INHIBITOR; TEMSIROLIMUS; THALIDOMIDE; VORINOSTAT; ANTINEOPLASTIC AGENT;

EID: 77956814361     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2010.08262.x     Document Type: Review
Times cited : (20)

References (94)
  • 1
    • 33947280591 scopus 로고    scopus 로고
    • Targeted therapy of multiple myeloma based upon tumor-microenvironmental interactions
    • Anderson, K.C. (2007) Targeted therapy of multiple myeloma based upon tumor-microenvironmental interactions. Experimental Hematology, 35, 155 162.
    • (2007) Experimental Hematology , vol.35 , pp. 155-162
    • Anderson, K.C.1
  • 7
    • 34047271640 scopus 로고    scopus 로고
    • Arsenic trioxide induces apoptosis via the mitochondrial pathway by upregulating the expression of Bax and Bim in human B cells
    • Baysan, A., Yel, L., Gollapudi, S., Su, H. Gupta, S. (2007) Arsenic trioxide induces apoptosis via the mitochondrial pathway by upregulating the expression of Bax and Bim in human B cells. International Journal of Oncology, 30, 313 318.
    • (2007) International Journal of Oncology , vol.30 , pp. 313-318
    • Baysan, A.1    Yel, L.2    Gollapudi, S.3    Su, H.4    Gupta, S.5
  • 16
    • 63149128755 scopus 로고    scopus 로고
    • Dendritic cell-based therapeutic vaccination against myeloma: Vaccine formulation determines efficacy against light chain myeloma
    • Cohen, S., Haimovich, J. Hollander, N. (2009) Dendritic cell-based therapeutic vaccination against myeloma: vaccine formulation determines efficacy against light chain myeloma. Journal of Immunology, 182, 1667 1673.
    • (2009) Journal of Immunology , vol.182 , pp. 1667-1673
    • Cohen, S.1    Haimovich, J.2    Hollander, N.3
  • 17
    • 72049083386 scopus 로고    scopus 로고
    • Exploring mammalian target of rapamycin (mTOR) inhibition for treatment of mantle cell lymphoma and other hematologic malignancies
    • Coiffier, B. Ribrag, V. (2009) Exploring mammalian target of rapamycin (mTOR) inhibition for treatment of mantle cell lymphoma and other hematologic malignancies. Leukaemia & Lymphoma, 50, 1916 1930.
    • (2009) Leukaemia & Lymphoma , vol.50 , pp. 1916-1930
    • Coiffier, B.1    Ribrag, V.2
  • 18
    • 61349121551 scopus 로고    scopus 로고
    • Regulation of the CD56 promoter and its association with proliferation, anti-apoptosis and clinical factors in multiple myeloma
    • Damgaard, T., Knudsen, L.M., Dahl, I.M., Gimsing, P., Lodahl, M. Rasmussen, T. (2009) Regulation of the CD56 promoter and its association with proliferation, anti-apoptosis and clinical factors in multiple myeloma. Leukaemia & Lymphoma, 50, 236 246.
    • (2009) Leukaemia & Lymphoma , vol.50 , pp. 236-246
    • Damgaard, T.1    Knudsen, L.M.2    Dahl, I.M.3    Gimsing, P.4    Lodahl, M.5    Rasmussen, T.6
  • 19
    • 72149090432 scopus 로고    scopus 로고
    • Evaluating temsirolimus activity in multiple tumors: A review of clinical trials
    • Dancey, J.E., Curiel, R. Purvis, J. (2009) Evaluating temsirolimus activity in multiple tumors: a review of clinical trials. Seminars in Oncology, 36 (Suppl 3 S46 S58.
    • (2009) Seminars in Oncology , vol.36 , Issue.SUPPL. 3
    • Dancey, J.E.1    Curiel, R.2    Purvis, J.3
  • 20
    • 34948890040 scopus 로고    scopus 로고
    • Heat shock protein inhibition is associated with activation of the unfolded protein response pathway in myeloma plasma cells
    • Davenport, E.L., Moore, H.E., Dunlop, A.S., Sharp, S.Y., Workman, P., Morgan, G.J. Davies, F.E. (2007) Heat shock protein inhibition is associated with activation of the unfolded protein response pathway in myeloma plasma cells. Blood, 110, 2641 2649.
    • (2007) Blood , vol.110 , pp. 2641-2649
    • Davenport, E.L.1    Moore, H.E.2    Dunlop, A.S.3    Sharp, S.Y.4    Workman, P.5    Morgan, G.J.6    Davies, F.E.7
  • 23
    • 67649625171 scopus 로고    scopus 로고
    • Tanespimycin: The opportunities and challenges of targeting heat shock protein 90
    • Erlichman, C. (2009) Tanespimycin: the opportunities and challenges of targeting heat shock protein 90. Expert Opinion on Investigational Drugs, 18, 861 868.
    • (2009) Expert Opinion on Investigational Drugs , vol.18 , pp. 861-868
    • Erlichman, C.1
  • 26
    • 74049113834 scopus 로고    scopus 로고
    • A phase II multiple dose clinical trial of histone deacetylase inhibitor ITF2357 in patients with relapsed or progressive multiple myeloma
    • Galli, M., Salmoiraghi, S., Golay, J., Gozzini, A., Crippa, C., Pescosta, N. Rambaldi, A. (2010) A phase II multiple dose clinical trial of histone deacetylase inhibitor ITF2357 in patients with relapsed or progressive multiple myeloma. Annals of Hematology, 89, 185 190.
    • (2010) Annals of Hematology , vol.89 , pp. 185-190
    • Galli, M.1    Salmoiraghi, S.2    Golay, J.3    Gozzini, A.4    Crippa, C.5    Pescosta, N.6    Rambaldi, A.7
  • 28
    • 67049115481 scopus 로고    scopus 로고
    • Proteomic and functional analyses reveal a dual molecular mechanism underlying arsenic-induced apoptosis in human multiple myeloma cells
    • Ge, F., Lu, X.P., Zeng, H.L., He, Q.Y., Xiong, S. Jin, L. (2009) Proteomic and functional analyses reveal a dual molecular mechanism underlying arsenic-induced apoptosis in human multiple myeloma cells. J Proteome Res, 8, 3006 3019.
    • (2009) J Proteome Res , vol.8 , pp. 3006-3019
    • Ge, F.1    Lu, X.P.2    Zeng, H.L.3    He, Q.Y.4    Xiong, S.5    Jin, L.6
  • 35
    • 70349643684 scopus 로고    scopus 로고
    • Final results of PX-171-003-A0, part 1 of an open-label, single-arm, phase II study of carfilzomib (CFZ) in patients (pts) with relapsed and refractory multiple myeloma (MM)
    • Abstract 8504
    • Jagannath, S., Vij, R., Stewart, K., Somlo, G., Jakubowiak, A., Trudel, S., Schwartz, R., Siegel, D., Kunkel, L. The Multiple Myeloma Research, C. (2009) Final results of PX-171-003-A0, part 1 of an open-label, single-arm, phase II study of carfilzomib (CFZ) in patients (pts) with relapsed and refractory multiple myeloma (MM). Journal of Clinical Oncology (ASCO Meeting Abstracts), 27, 435s. Abstract 8504.
    • (2009) Journal of Clinical Oncology (ASCO Meeting Abstracts) , vol.27
    • Jagannath, S.1    Vij, R.2    Stewart, K.3    Somlo, G.4    Jakubowiak, A.5    Trudel, S.6    Schwartz, R.7    Siegel, D.8    Kunkel, L.9
  • 39
    • 0141484615 scopus 로고    scopus 로고
    • A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors
    • Kamal, A., Thao, L., Sensintaffar, J., Zhang, L., Boehm, M.F., Fritz, L.C. Burrows, F.J. (2003) A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors. Nature, 425, 407 410.
    • (2003) Nature , vol.425 , pp. 407-410
    • Kamal, A.1    Thao, L.2    Sensintaffar, J.3    Zhang, L.4    Boehm, M.F.5    Fritz, L.C.6    Burrows, F.J.7
  • 45
    • 33745124885 scopus 로고    scopus 로고
    • Prognostic Value of Syndecan-1 in Multiple Myeloma and its Relationship with Other Prognostic Factors
    • Abstract 2402
    • Kumar, S., Blood, E., Oken, M.M. Greipp, P.R. (2004) Prognostic Value of Syndecan-1 in Multiple Myeloma and its Relationship with Other Prognostic Factors. Blood (ASH Annual Meeting Abstracts), 104, 660a. Abstract 2402.
    • (2004) Blood (ASH Annual Meeting Abstracts) , vol.104
    • Kumar, S.1    Blood, E.2    Oken, M.M.3    Greipp, P.R.4
  • 47
    • 44049083639 scopus 로고    scopus 로고
    • Targeting the Bcl-2-regulated apoptosis pathway by BH3 mimetics: A breakthrough in anticancer therapy?
    • Labi, V., Grespi, F., Baumgartner, F. Villunger, A. (2008) Targeting the Bcl-2-regulated apoptosis pathway by BH3 mimetics: a breakthrough in anticancer therapy? Cell Death and Differentiation, 15, 977 987.
    • (2008) Cell Death and Differentiation , vol.15 , pp. 977-987
    • Labi, V.1    Grespi, F.2    Baumgartner, F.3    Villunger, A.4
  • 52
    • 77953663858 scopus 로고    scopus 로고
    • Antibody-maytansinoid conjugates for the treatment of myeloma
    • Lutz, R.J. Whiteman, K.R. (2009) Antibody-maytansinoid conjugates for the treatment of myeloma. mAbs, 1, 548 551.
    • (2009) MAbs , vol.1 , pp. 548-551
    • Lutz, R.J.1    Whiteman, K.R.2
  • 54
    • 1842844361 scopus 로고    scopus 로고
    • Neural cell adhesion molecule expression in plasma cells in bone marrow biopsies and aspirates allows discrimination between multiple myeloma, monoclonal gammopathy of uncertain significance and polyclonal plasmacytosis
    • Martin, P., Santon, A. Bellas, C. (2004) Neural cell adhesion molecule expression in plasma cells in bone marrow biopsies and aspirates allows discrimination between multiple myeloma, monoclonal gammopathy of uncertain significance and polyclonal plasmacytosis. Histopathology, 44, 375 380.
    • (2004) Histopathology , vol.44 , pp. 375-380
    • Martin, P.1    Santon, A.2    Bellas, C.3
  • 58
    • 58149086029 scopus 로고    scopus 로고
    • High response rate to bortezomib with or without dexamethasone in patients with relapsed or refractory multiple myeloma: Results of a global phase 3b expanded access program
    • Mikhael, J.R., Belch, A.R., Prince, H.M., Lucio, M.N., Maiolino, A., Corso, A., Petrucci, M.T., Musto, P., Komarnicki, M. Stewart, A.K. (2009) High response rate to bortezomib with or without dexamethasone in patients with relapsed or refractory multiple myeloma: results of a global phase 3b expanded access program. British Journal Haematology, 144, 169 175.
    • (2009) British Journal Haematology , vol.144 , pp. 169-175
    • Mikhael, J.R.1    Belch, A.R.2    Prince, H.M.3    Lucio, M.N.4    Maiolino, A.5    Corso, A.6    Petrucci, M.T.7    Musto, P.8    Komarnicki, M.9    Stewart, A.K.10
  • 63
    • 44849085132 scopus 로고    scopus 로고
    • Bcl-2-targeted antisense therapy (Oblimersen sodium): Towards clinical reality
    • Moreira, J.N., Santos, A. Simoes, S. (2006) Bcl-2-targeted antisense therapy (Oblimersen sodium): towards clinical reality. Reviews on Recent Clinical Trials, 1, 217 235.
    • (2006) Reviews on Recent Clinical Trials , vol.1 , pp. 217-235
    • Moreira, J.N.1    Santos, A.2    Simoes, S.3
  • 64
    • 56449128746 scopus 로고    scopus 로고
    • New drugs in multiple myeloma: Mechanisms of action and phase I/II clinical findings
    • Ocio, E.M., Mateos, M.V., Maiso, P., Pandiella, A. San-Miguel, J.F. (2008) New drugs in multiple myeloma: mechanisms of action and phase I/II clinical findings. The Lancet Oncology, 9, 1157 1165.
    • (2008) The Lancet Oncology , vol.9 , pp. 1157-1165
    • Ocio, E.M.1    Mateos, M.V.2    Maiso, P.3    Pandiella, A.4    San-Miguel, J.F.5
  • 66
    • 36349005782 scopus 로고    scopus 로고
    • Anticancer therapy targeting telomeres and telomerase : Current status
    • Parkinson, E.K. Minty, F. (2007) Anticancer therapy targeting telomeres and telomerase : current status. BioDrugs, 21, 375 385.
    • (2007) BioDrugs , vol.21 , pp. 375-385
    • Parkinson, E.K.1    Minty, F.2
  • 67
    • 2542523228 scopus 로고    scopus 로고
    • Synergistic induction of oxidative injury and apoptosis in human multiple myeloma cells by the proteasome inhibitor bortezomib and histone deacetylase inhibitors
    • Pei, X.Y., Dai, Y. Grant, S. (2004) Synergistic induction of oxidative injury and apoptosis in human multiple myeloma cells by the proteasome inhibitor bortezomib and histone deacetylase inhibitors. Clinical Cancer Research, 10, 3839 3852.
    • (2004) Clinical Cancer Research , vol.10 , pp. 3839-3852
    • Pei, X.Y.1    Dai, Y.2    Grant, S.3
  • 69
    • 36448955418 scopus 로고    scopus 로고
    • Telomerase and its potential for therapeutic intervention
    • Phatak, P. Burger, A.M. (2007) Telomerase and its potential for therapeutic intervention. British Journal of Pharmacology, 152, 1003 1011.
    • (2007) British Journal of Pharmacology , vol.152 , pp. 1003-1011
    • Phatak, P.1    Burger, A.M.2
  • 70
    • 67449152479 scopus 로고    scopus 로고
    • Toward an effective targeted chemotherapy for multiple myeloma
    • Polson, A.G. Sliwkowski, M.X. (2009) Toward an effective targeted chemotherapy for multiple myeloma. Clinical Cancer Research, 15, 3906 3907.
    • (2009) Clinical Cancer Research , vol.15 , pp. 3906-3907
    • Polson, A.G.1    Sliwkowski, M.X.2
  • 72
    • 34848826210 scopus 로고    scopus 로고
    • Management of multiple myeloma: The changing landscape
    • Reece, D.E. (2007) Management of multiple myeloma: the changing landscape. Blood Reviews, 21, 301 314.
    • (2007) Blood Reviews , vol.21 , pp. 301-314
    • Reece, D.E.1
  • 80
    • 67849084851 scopus 로고    scopus 로고
    • The efficacy of arsenic trioxide for the treatment of relapsed and refractory multiple myeloma: A systematic review
    • Rollig, C. Illmer, T. (2009) The efficacy of arsenic trioxide for the treatment of relapsed and refractory multiple myeloma: a systematic review. Cancer Treatment Reviews, 35, 425 430.
    • (2009) Cancer Treatment Reviews , vol.35 , pp. 425-430
    • Rollig, C.1    Illmer, T.2
  • 86
    • 76449105686 scopus 로고    scopus 로고
    • The potential role of epigenetic therapy in multiple myeloma
    • Smith, E.M., Boyd, K. Davies, F.E. (2010) The potential role of epigenetic therapy in multiple myeloma. British Journal of Haematology, 148, 702 713.
    • (2010) British Journal of Haematology , vol.148 , pp. 702-713
    • Smith, E.M.1    Boyd, K.2    Davies, F.E.3


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