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Badros, A.Z., Goloubeva, O., Rapoport, A.P., Ratterree, B., Gahres, N., Meisenberg, B., Takebe, N., Heyman, M., Zwiebel, J., Streicher, H., Gocke, C.D., Tomic, D., Flaws, J.A., Zhang, B. Fenton, R.G. (2005) Phase II study of G3139, a Bcl-2 antisense oligonucleotide, in combination with dexamethasone and thalidomide in relapsed multiple myeloma patients. Journal of Clinical Oncology, 23, 4089 4099.
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Final results of PX-171-003-A0, part 1 of an open-label, single-arm, phase II study of carfilzomib (CFZ) in patients (pts) with relapsed and refractory multiple myeloma (MM)
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Abstract 8504
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Jagannath, S., Vij, R., Stewart, K., Somlo, G., Jakubowiak, A., Trudel, S., Schwartz, R., Siegel, D., Kunkel, L. The Multiple Myeloma Research, C. (2009) Final results of PX-171-003-A0, part 1 of an open-label, single-arm, phase II study of carfilzomib (CFZ) in patients (pts) with relapsed and refractory multiple myeloma (MM). Journal of Clinical Oncology (ASCO Meeting Abstracts), 27, 435s. Abstract 8504.
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Phase i results of perifosine (KRX-0401) in combination with lenalidomide and dexamethasone in patients with relapsed or refractory multiple myeloma (MM)
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Abstract 3691
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Jakubowiak, A., Richardson, P., Zimmerman, T.M., Alsina, M., Kaufman, J.L., Harvey, C., Brozo, C., Kendall, T., McAllister, A., Hideshima, T., Sportelli, P., Gardner, L., Anderson, K.C. Giusti, K. (2008) Phase I results of perifosine (KRX-0401) in combination with lenalidomide and dexamethasone in patients with relapsed or refractory multiple myeloma (MM). Blood (ASH Annual Meeting Abstracts), 112, 1264. Abstract 3691.
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37
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Lenalidomide, bortezomib, pegylated liposomal doxorubicin hydrochloride, and dexamethasone in newly diagnosed multiple myeloma: Initial results of phase I/II MMRC trial
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Abstract 8517
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Jakubowiak, A.J., Hofmeister, C.C., Campagnaro, E.L., Zimmerman, T.M., Schlossman, R.L., Lonial, S., Reece, D.E., Kaminski, M.S., Anderson, K.C. Richardson, P.G. (2009a) Lenalidomide, bortezomib, pegylated liposomal doxorubicin hydrochloride, and dexamethasone in newly diagnosed multiple myeloma: initial results of phase I/II MMRC trial. Journal of Clinical Oncology (ASCO Meeting Abstracts), 27, 438s. Abstract 8517.
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Jakubowiak, A.J.1
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Lonial, S.6
Reece, D.E.7
Kaminski, M.S.8
Anderson, K.C.9
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38
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Phase 1/2 study of elotuzumab in combination with bortezomib in patients with multiple myeloma with one to three prior therapies: Interim results
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Abstract 3876
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Jakubowiak, A.J., Bensinger, W., Siegel, D., Zimmerman, T.M., Van Tornout, J.M., Zhao, C., Singhal, A. Anderson, K. (2009b) Phase 1/2 study of elotuzumab in combination with bortezomib in patients with multiple myeloma with one to three prior therapies: interim results. Blood (ASH Annual Meeting Abstracts), 114, 1491. Abstract 3876.
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Zhao, C.6
Singhal, A.7
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70449477567
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Improved survival of patients with multiple myeloma after the introduction of novel agents and the applicability of the International Staging System (ISS) an analysis of the Greek Myeloma Study Group (GMSG)
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Abstract 655
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Kastritis, E., Zervas, K., Symeonidis, A., Terpos, E., Delimpassi, S., Anagnostopoulos, N., Michali, E., Zomas, A., Katodritou, I., Gika, D., Pouli, A., Christoulas, D., Roussou, M., Economopoulos, T. Dimopoulos, M.A. (2008) Improved survival of patients with multiple myeloma after the introduction of novel agents and the applicability of the International Staging System (ISS) an analysis of the Greek Myeloma Study Group (GMSG). Blood (ASH Annual Meeting Abstracts), 112, 244. Abstract 655.
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Kawauchi, K., Ogasawara, T., Yasuyama, M., Otsuka, K. Yamada, O. (2009) The PI3K/Akt pathway as a target in the treatment of hematologic malignancies. Anti-Cancer Agents in Medicinal Chemistry, 9, 550 559.
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Activation of SHIP via a small molecule agonist kills multiple myeloma cells
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Kennah, M., Yau, T.Y., Nodwell, M., Krystal, G., Andersen, R.J., Ong, C.J. Mui, A.L. (2009) Activation of SHIP via a small molecule agonist kills multiple myeloma cells. Experimental Hematology, 37, 1274 1283.
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Potent activity of carfilzomib, a novel, irreversible inhibitor of the ubiquitin-proteasome pathway, against preclinical models of multiple myeloma
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Kuhn, D.J., Chen, Q., Voorhees, P.M., Strader, J.S., Shenk, K.D., Sun, C.M., Demo, S.D., Bennett, M.K., van Leeuwen, F.W., Chanan-Khan, A.A. Orlowski, R.Z. (2007) Potent activity of carfilzomib, a novel, irreversible inhibitor of the ubiquitin-proteasome pathway, against preclinical models of multiple myeloma. Blood, 110, 3281 3290.
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Prognostic Value of Syndecan-1 in Multiple Myeloma and its Relationship with Other Prognostic Factors
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Abstract 2402
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Kumar, S., Blood, E., Oken, M.M. Greipp, P.R. (2004) Prognostic Value of Syndecan-1 in Multiple Myeloma and its Relationship with Other Prognostic Factors. Blood (ASH Annual Meeting Abstracts), 104, 660a. Abstract 2402.
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Abstract 3404
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Kyrtsonis, M.-C., Vassilakopoulos, T.P., Papadogiannis, A., Tzenou, T., Kalpadakis, C., Antoniadis, A., Dimopoulou, M.N., Siakantaris, M.P., Kokoris, S.I., Dimitriadou, E.M., Angelopoulou, M.K., Plata, E., Tsaftaridis, P. Pangalis, G.A. (2005) Serum Soluble Syndecan-1 Levels at Diagnosis Constitute an Independent Prognostic Factor of Survival in Myeloma That May Further Differentiate Patients within the ISS Stages. Blood (ASH Annual Meeting Abstracts), 106, 951a. Abstract 3404.
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Lacy, M.Q., Hayman, S.R., Gertz, M.A., Allred, J.B., Mandrekar, S.J., Dispenzieri, A., Zeldenrust, S.R., Kumar, S., Greipp, P.R., Lust, J.A., Russell, S.J., Buadi, F., Kyle, R.A., Bergsagel, P.L., Fonseca, R., Roy, V., Mikhael, J., Stewart, A.K. Rajkumar, S.V. (2008) Pomalidomide (CC4047) plus low-dose dexamethasone (pom/dex) is highly effective therapy in relapsed multiple myeloma. Blood (ASH Annual Meeting Abstracts), 112, 320. Abstract 866.
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Lin, P., Owens, R., Tricot, G. Wilson, C.S. (2004) Flow cytometric immunophenotypic analysis of 306 cases of multiple myeloma. American Journal of Clinical Pathology, 121, 482 488.
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Abstract 432
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Syndecan-1 is essential for the myeloma cell growth factor activity of EGF-family ligands in multiple myeloma
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Mahtouk, K., Cremer, F.W., Reme, T., Jourdan, M., Baudard, M., Moreaux, J., Requirand, G., Fiol, G., De Vos, J., Moos, M., Quittet, P., Goldschmidt, H., Rossi, J.-F., Hose, D. Klein, B. (2005) Syndecan-1 Is Essential for the Myeloma Cell Growth Factor Activity of EGF-Family Ligands in Multiple Myeloma. Blood (ASH Annual Meeting Abstracts), 106, 186a. Abstract 626.
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Neural cell adhesion molecule expression in plasma cells in bone marrow biopsies and aspirates allows discrimination between multiple myeloma, monoclonal gammopathy of uncertain significance and polyclonal plasmacytosis
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Mikhael, J.R., Belch, A.R., Prince, H.M., Lucio, M.N., Maiolino, A., Corso, A., Petrucci, M.T., Musto, P., Komarnicki, M. Stewart, A.K. (2009) High response rate to bortezomib with or without dexamethasone in patients with relapsed or refractory multiple myeloma: results of a global phase 3b expanded access program. British Journal Haematology, 144, 169 175.
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