Malondialdehyde (MDA) and protein carbonyl (PCO) levels as biomarkers of oxidative stress in subjects with familial hypercholesterolemia

Clinical Biochemistry

Volumn 43, Issue 15, 2010, Pages 1220-1224

  Pirinccioglu, Ayfer Gözü ^a   Gökalp, Deniz ^a   Pirinccioglu, Mihdiye ^a   Kizil, Göksel ^a   Kizil, Murat ^a  

^a DICLE UNIVERSITY   (Turkey)

Author keywords

Atherosclerosis; Familial; Hypercholesterolemia; Lipid peroxidation; Malondialdehyde; Oxidative stress; Protein carbonylation

Indexed keywords

CARBONYL DERIVATIVE; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPOPROTEIN A; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MALONALDEHYDE; TRIACYLGLYCEROL;

ADOLESCENT; ADULT; ARTERIAL WALL THICKNESS; ARTICLE; ATHEROSCLEROSIS; CHILD; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; FAMILIAL HYPERCHOLESTEROLEMIA; FEMALE; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; LIPID PEROXIDATION; LIPOPROTEIN BLOOD LEVEL; MALE; OXIDATIVE STRESS; PRIORITY JOURNAL; SCHOOL CHILD;

ADOLESCENT; ADULT; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CHILD; FEMALE; HUMANS; HYPERLIPOPROTEINEMIA TYPE II; MALE; MALONDIALDEHYDE; OXIDATIVE STRESS; PROTEIN CARBONYLATION; YOUNG ADULT;

EID: 77956757897     PISSN: 00099120     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clinbiochem.2010.07.022     Document Type: Article

References (39)

1. Goldstein J.L., Brown M.S. The LDL receptor focus and relation to genetics of familial hypercholesterolaemia. Annu Rev 1979, 13:259-289.
2. Risk of fatal coronary heart disease in familial hypercholesterolemia. BMJ 1991, 303:893-896. Scientific Steering Committee on behalf of the Simon Broome Register Group.
3. Goldstein J.L., Hobbs H., Brown M.S. Familial hypercholesterolemia. The methabolic and molecular basis of inherited disease 2001, 2863-2913. McGraw-Hill, New York, USA. C. Scriver, A. Beaude, W. Sly, D. Vall (Eds.).
4. Rader D.J., Cohen J., Hobbs H.H. Monogenic hypercholesterolemia: new insights in pathogenesis and treatment. J Clin Invest 2003, 111:1795-1803.
5. Hartvigsen K., Chou M.Y., Hansen L.F., Shaw P.X., Tsimikas S., Binder C.J., Witztum J.L. The role of innate immunity in atherogenesis. J Lipid Res 2009, S388-S393.
6. Duarte M.M.M.F., Rocha J.B.T., Moresco R.N., Duarte T., Da Cruz I.B.M., Loro V.L., Schetinger M.R.C. Association between ischemia-modified albumin, lipids and inflammation biomarkers in patients with hypercholesterolemia. Clin Biochem 2009, 42:666-671.
7. Vassalle C., Pratali L., Boni C. An oxidative stress score as a combined measure of the pro-oxidant and anti-oxidant counterparts in patients with coronary artery disease. Clin Biochem 2008, 41:1162-1167.
8. Cederberg J., Basu S., Eriksson U.J. Increased rate of lipid peroxidation and protein carbonylation in experimental diabetic pregnancy. Diabetologia 2001, 44:766-774.
9. Kirkova M., Ivancheva E., Russannova E. Lipid peroxidation and antioxidant enzyme activity in aspirin-treated rats. Gen Pharmacol 1995, 26:613-617.
10. Mates J.M., Perez-Gomez C., Olalla L., Segura J.M., Blanca M. Allergy to drugs: antioxidant enzymic activities, lipid peroxidation and protein oxidative damage in human blood. Cell Biochem Funct 2000, 18:77-84.
11. Dalle-Donne I., Adlini G., Carini M., Colombo R., Rossi R., Milzani A. Protein carbonylation, cellular dysfunction, and disease progression. J Cell Mol Med 2006, 10:389-406.
12. Dalle-Donne I., Giustarini D., Colombo R., Rossi R., Milzani A. Protein carbonylation in human diseases. Trends Mol Med 2003, 9:169-176.
13. Stadtman E.R., Levine R.L. Free radical-mediated oxidation of free amino acids and amino acid residues in proteins. Amino Acids 2005, 25:207-218.
14. Friedewald W.T., Levy R.I., Fredrickson D.S. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 1972, 18:499-502.
15. Lowry O.H., Rosebrough N.J., Farr A.L., Randall R.J. Protein measurement with the folin-phenol reagent. J Biol Chem 1951, 193:265-275.
16. Buege J.A., Aust J.D. Microsomal lipid peroxidation. Methods Enzymol 1978, 52:302-310.
17. Levine R.L., Garland D., Oliver C.N., Amici A., Climent I., Lenz A.G., Ahn B.W., Shaltiel S., Statdtman E.R. Determination of carbonyl content in oxidatively modified proteins. Methods Enzymol 1990, 186:464-478.
18. Dalle-Donne I., Rossi R., Colombo R., Giustarini D., Milzani A. Biomarkers of oxidative damage in human disease. Clin Chem 2006, 52:601-623.
19. Ungvari Z., Parrado-Fermamdez C., Csoszar A., de Caba R. Mechanisms underlying caloric restriction and lifespan regulation. Implication for vascular aging. Circ Res 2008, 102:519-528.
20. Fung T.T., Rexrode K.M., Mantzoros C.S., Manson J.E., Willett W.C., Hu F.B. Mediterranean diet and incidence of and mortality from coronary heart disease and stroke in women. Circulation 2009, 119:1093-1100.
21. Konhilas J.P., Leinwand L.A. The effect of biological sex and diet on the development of heart failure. Circulation 2007, 116:2747-2759.
22. Romero J.C., Reckelhoff J.F. Role of angiotensin and oxidative stress in essential hypertension. Hypertension 1999, 34:943-949.
23. Redon J., Oliva M.R., Tormos C., Giner V., Chaves J., Iradi A., Saez G.T. Antioxidant activities and oxidative byproducts in human hypertension. Hypertension 2003, 41:1096-2001.
24. Murray C.J.L., Lopez A.D. Global mortality, disability, and the contribution of risk factors: global burden of disease study. Lancet 1997, 349:1436-1442.
25. Heistad D.D. Oxidative stress and vascular disease: 2005 Duff lecture. Arterioscler Thromb Vasc Biol 2006, 26:689-695.
26. Papaharalambus C.A., Griendling K.K. Basic mechanisms of oxidative stress and reactive oxygen species in cardiovascular injury. Trends Cardiovasc Med 2007, 17:48-54.
27. Dalle-Donne I., Giustarini D., Colombo R., Rossi R., Milzani A. Protein carbonylation in human diseases. Trends Mol Med 2003, 9:169-176.
28. Stadtman E.R., Levine R.L. Free radical-mediated oxidation of free amino acids and amino acid residues in proteins. Amino Acids 2003, 25:207-218.
29. Nourooz-Zadeh J., Smith C.C.T., Betteridge D.J. Measures of oxidative stress in heterozygous familial hypercholesterolaemia. Atherosclerosis 2001, 156:435-441.
30. Wittenstein B., Klein M., Finckh B., Ullrich K., Kohlschutter A. Plasma antioxidants in pediatric patients with glycogen storage disease, diabetes mellitus, and hypercholesterolemia. Free Radic Biol Med 2002, 33:103-110.
31. Kurtoglu E., Ugur A., Sait Gonen M., Kisakol G. Effect of lipoprotein apheresis on oxidative stress and antioxidant status in familial hypercholesterolemic patients. Int J Artif Organ 2003, 26:1039-1043.
32. Efe H., Kirci D., Deger O., Yildirmis S., Uydu H.A., Orem C. Erythrocyte antioxidant enzyme activities and lipid peroxidation in patients with types IIb and IV hyperlipoproteinemias. Tohoku J Exp Med 2004, 202:163-172.
33. Real J.T., Martinez-Hervas S., Tormos M.C., Domenech E., Pallardo F.V., Saez-Tormo G., Redon J., Carmena R., Chaves F.J., Ascaso J.F., Garcia-Garcia A.B. Increased oxidative stress levels and normal antioxidant enzyme activity in circulating mononuclear cells from patients of familial hypercholesterolemia. Metabolism 2010, 59:293-298.
34. Jarvisalo M.J., Jartti L., Nanto-Salonen K., Irjala K., Ronnemaa T., Hartiala J.J., Celermajer D.S., Raitakari O.T. Increased aortic intima-media thickness: a marker of preclinical atherosclerosis in high-risk children. Circulation 2001, 104:2943-2947.
35. Wiegman A., Hutten B.A., de Groot E., Rodenburg J., Bakker H.D., Buller H.R., Sijbrands E.J., Kastelein J.J.P. Efficacy and safety of statin therapy in children with familial hypercholesterolemia: a randomized controlled trial. JAMA 2004, 292:331-337.
36. de Jongh S., Lilien M.R., op't Roodt R.J., Stroes E.S., Bakker H.D., Kastelein J.J. Early statin therapy restores endothelial function in children with familial hypercholesterolemia. J Am Coll Cardiol 2002, 40:2117-2121.
37. Celermajer D.S., Sorensen K.E., Gooch V.M., Sullivan I.D., Lloyd J.K., Deanfield J.E. Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis. Lancet 1992, 340:1111-1115.
38. Sorensen K.E., Celermajer D.S., Georgakopoulos D., Hatcher G., Betteridge D.J., Deanfield J.E. Impairment of endothelium-dependent dilation is an early event in children with familial hypercholesterolemia and is related to the lipoprotein(a) level. J Clin Invest 1994, 93:50-55.
39. Galle J., Schollmeyer P., Wanner C. Impairment of endothelium-dependent vasodilation in rabbit renal arteries by oxidized lipoprotein(a). Role of oxygen-derived radicals. Circulation 1995, 92:1582-1589.