Neurological Disease

Advances in Pharmacology

Volumn 38, Issue C, 1996, Pages 557-580

  Muller, David P R ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 77956751817     PISSN: 10543589     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S1054-3589(08)60999-0     Document Type: Article

References (147)

1. Adler L.A., Peselow E., Rotroson J., Duncan E., Lee M., Rosenthal M., and Angrist B. Vitamin E treatment of tardive dyskinesia. Am. J. Psych. 150 (1993) 1405-1407
2. Alvarez F., Landrieu P., Laget P., Lemonnier F., Odievre M., and Alagille D. Nervous and ocular disorders in children with cholestasis and vitamin A and E deficiences. Hepatology 3 (1983) 410-414
3. Anderson D.K., and Mearns E.D. Lipid peroxidation in spinal cord: FeCl2 induction and protection with antioxidants. Neurochem. Pathol. 1 (1983) 249-264
4. Avraham K.B., Schickler M., Sapoznikov D., Yarom R., and Groner Y. Down's syndrome: Abnormal neuromuscular function in tongue of transgenic mice with elevated levels of human Cu/Zn superoxide dismutase. Cell 54 (1988) 823-829
5. Azizi E., Zaidman J.L., Eschar J., and Szeinberg A. Abetalipoproteinaemia treated with parenteral and oral vitamins A and E and with medium chain triglycerides. Acta Pediatr. Scand. 67 (1978) 797-801
6. Beckman J.S. The double-edged role of nitric oxide in brain function and superoxide mediated injury. J. Dev. Physiol. 15 (1991) 53-59
7. Beckman J.S., Carson M., and Smith C.D. ALS, SOD and peroxinitrite. Nature 364 (1993) 584
8. Beneveniste H., Drejer J., Schousboe A., and Diemer N.H. Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis. J. Neurochem. 43 (1984) 1369-1374
9. Bishara S., Merin S., Cooper M., Azizi E., Delpre G., and Deckelbaum R.J. Combined vitamin A and E therapy prevents retinal electrophysiological deterioration in abetalipoproteinaemia. Br. J. Ophthalmol. 66 (1982) 767-770
10. Bohlmann H.E., Thiede H., Rosenstiel K., Herdermenten S., Panitz D., and Tackmann W. Abetalipoproteinamie bei drei Geschwiston. Dtsch Med. Wochenschr. 97 (1972) 892-896
11. Bondy S.C. The relation of oxidative stress and hyperexcitation to neurological disease. Proc. Soc. Exp. Biol. Med. 208 (1995) 337-345
12. Bowling A.C., Schulz J.B., Brown R.H.J., and Beal M.F. Superoxide dismutase activity, oxidative damage and mitochondrial energy metabolism in familial and sporadic amyotrophic lateral sclerosis. J. Neurochem. 61 (1993) 2322-2325
13. Braughler J.M., and Hall E.D. Central nervous system trauma and stroke. I. Biochemical considerations for oxygen radical formation and lipid peroxidation. Free Rad. Biol. Med. 6 (1989) 289-301
14. Brooksbank B.W.L., and Balazs R. Superoxide dismutase, glutathione peroxidase and lipoperoxidation in Down's syndrome fetal brain. Dev. Brain Res. 16 (1995) 37-44
15. Brown R.H.J. Amyotrophic lateral sclerosis: Recent insights from genetics and transgenic mice. Cell 80 (1995) 687-692
16. Burton G.W., Joyce A., and Ingold K.U. Is vitamin E the only lipid soluble chain-breaking antioxidant in human blood plasma and erythrocyte membranes?. Arch. Biochem. Biophys. 221 (1983) 281-290
17. Cadet J.L., Lohr J.B., and Jeste D.V. Free radicals and tardive dyskinesia. Trends Neurosci. 9 (1986) 107-108
18. Carney J.M., and Floyd R.A. Protection against oxidative damage to CNS by a-phenyl-tert-butyl nitrone (PBN) and other spin-trapping agents: A novel eries of nonlipid free radical scavengers. J. Mol. Neurosci. 3 (1991) 47-57
19. Ceballos-Picot I., Delabas J.M., Nicole A., Lynch R.E., Hallewell R.A., Kamoun P., and Sinet P.M. Expression of transfected Cu/Zn superoxide dismutase gene in mouse L cells and NS 20Y neuroblastoma cells induces enhancement of glutathione peroxidase activity. Biochim. Biophys. Acta 949 (1988) 58-64
20. Ceballos-Picot I., Nicole A., Briand P., Grimber G., Delacourte A., Defossez A., Javoy-Agid F., Lafon M., Blouin J.L., and Sinet P.M. Neuronal specific expression of human copper-zinc superoxide dismutase in transgenic mice: animal model of gene dosage in Down's syndrome. Brain Res. 552 (1991) 198-214
21. Chan P.H., Fishman R.A., and Longar S.M. Brain injury edema, and vascular permeability changes induced by oxygen-derived free radicals. Neurology 34 (1984) 315-320
22. Chiswick M.L., Johnson M., Woodall C., Gowland M., Davies J., Toner N., and Sims D.G. Protective effect of vitamin E (DL-alpha-tocopherol) against intraventricular haemorrhage in premature babies. BMJ 287 (1983) 81-84
23. Cleeter M.W.J., Cooper J.M., and Schapira A.H.V. Irreversible inhibition of mitochondrial complex 1 by 1-methyl-4-phenylpyridinium: evidence for free radical involvement. J. Neurochem. 58 (1992) 786-789
24. Cohen B.M., and Zubenko G.S. In vivo effects of psychotropic agents on the physical properties of cell membranes in the rat brain. Psychophamacology 86 (1985) 365-368
25. Committee on Fetus and Newborn. Vitamin E and the prevention of retinopathy of prematurity. Pediatrics 76 (1985) 315-316
26. Dabiri L.M., Pasta D., Darby J.K., and Mosbacher D. Effectiveness of vitamin E for treatment of long-term tardive dyskinesia. Am. J. Psych. 151 (1994) 925-926
27. Davis G.C., Williams A.C., Markey S.P., Ebert M.H., Caine E.D., Reichert C.M., and Kopin L.J. Chronic parkinsonism secondary to intravenous injection of merperidine analogues. Psych. Res. 1 (1979) 249-254
28. Dawson T.M., Dawson V.L., and Snyder S.H. A novel neuronal messenger molecule in brain: The free radical, nitric oxide. Ann. Neurol. 32 (1992) 297-311
29. Deng H., Hentati A., Tainer J.A., Iqbal Z., Cayabyab A., Hung W., Getzoff E.D., Hu P., Herzfeldt B., Roos R.P., Warner C., Deng G., Soriano E., Smyth C., Parge H.E., Ahmed A., Roses A.D., Hallewell R.A., Pericak-Vance M.A., and Siddique T. Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase. Science 261 (1993) 1047-1051
30. Dexter D.T., Carayon A., Vidailhet M., Ruberg M., Agid F., Agid Y., Lees A.J., Wells F.R., Jenner P., and Marsden C.D. Decreased ferritin levels in brain in Parkinson's disease. J. Neurochem. 55 (1990) 16-20
31. Dexter D.T., Carter C.J., Wells F.R., Javoy-Agid F., Agid Y., Lees A., Jenner P., and Marsden C.D. Basal lipid peroxidation in substantia nigra is increased in Parkinson's disease. J. Neurochem. 52 (1989) 381-389
32. Dexter D.T., Wells F.R., Lees A.J., Agid F., Agid Y., Jenner P., and Marsden C.D. Increased nigral iron content and alterations in other metal ions occurring in brain in Parkinson's disease. J. Neurochem. 52 (1989) 1830-1836
33. Earle K.M. Studies on Parkinson's disease including X-ray, fluorescent spectroscopy of formalin-fixed brain tissue. J. Neuropathol. Exp. Neurol. 27 (1968) 1-14
34. Egan M.F., Hyde T.M., Albers G.W., Elkashef A., Alexander R.C., Reeve A., Blum A., Saeng R.E., and Wyatt R.J. Treatment of tardive dyskinesia with vitamin E. Am. J. Psych. 149 (1992) 773-777
35. Einarson L. Criticizing review of the concepts of the neuromuscular lesions in experimental vitamin E deficiency, preferably in adult rats. Acta Psych. Sand. 78 (1952) 9-76
36. Elias E., Muller D.P.R., and Scott J. Association of spinocerebellar disorders with cystic fibrosis or chronic childhood cholestasis and very low serum vitamin E. Lancet 2 (1981) 1319-1321
37. Elkashef A.M., Ruskin P.E., Bacher N., and Barren D. Vitamin E in the treatment of tardive dyskinesia. Am. J. Psych. 147 (1990) 505-506
38. Elroy-Stein O., Bernstein Y., and Groner Y. Overproduction of human Cu-Zn super-oxide dismutase in transfected cells: Extenuation of paraquat-mediated cytotoxicity and enhancement of lipid peroxidation. EMBO J. 5 (1986) 615-622
39. Engerson T.D., Mckelvey T.G., Rhyme D.B., Boggio E.B., Snyder S.J., and Jones H.P. Conversion of xanthine dehydrogenase to oxidase in ischemic rat tissues. J. Clin. Invest. 79 (1987) 1564-1570
40. Goss-Sampson M.A., Kriss A., and Muller D.P.R. A longitudinal study of somatosensory, brainstem auditory and peripheral sensory: Motor conduction during vitamin E deficiency in the rat. J. Neurol. Sci. 100 (1990) 79-84
41. Goss-Sampson M.A., Macevilly C.J., and Muller D.P.R. Longitudinal studies of the neurobiology of vitamin E and other antioxidant systems, and neurological function in the vitamin E deficient rat. J. Neurol. Sci. 87 (1988) 25-35
42. Goss-Sampson M.A., Muller D.P.R., and Kriss A. Abnormalities of the electroretinogram and visual evoked potential in vitamin E deficient rats. Exp. Eye Res. 53 (1991) 623-627
43. Gouras P., Carr R.E., and Gunkel R.D. Retinitis pigrnentosa in abetalipoproteinaemia: Effects of vitamin A. Invest. Ophthalmol. 10 (1971) 784-793
44. Graham D.G. On the origin and significance of neuromelanin. Arch. Pathol. Lab. Med. 103 (1979) 359-362
45. Granger D.N., Rutili G., and Mccord J.M. Superoxide radicals in feline intestinal ischemia. Gastroenterology 81 (1981) 22-29
46. Guggenheim M.A., Ringel S.P., Silverman A., and Grabert B.E. Progressive neuromuscular disease in children with chronic cholestasis and vitamin E deficiency: Diagnosis and treatment with alpha tocopherol. J. Pediatr. 100 (1982) 51-58
47. Gurney M.E., Pu H., Chiu A.Y., Canto M.C.D., Polchow C.Y., Alexander D.D., Caliendo J., Hentati A., Kwon Y.W., Deng H., Chen W., Zzhai P., Sufit R.L., and Siddique T. Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation. Science 264 (1994) 1772-1775
48. Gutteridge J.M., Quinlan G.J., Clark I., and Halliwell B. Aluminium salts accelerate peroxidation of membrane lipids stimulated by iron salts. Biochim. Biophys. Acta 835 (1985) 441-447
49. Hall E.D. Novel inhibitors of iron-dependent lipid peroxidation for neurodegenerative disorders. Ann. Neurol. 32 (1992) S137-S142
50. Hall E.D., and Braughler J.M. Central nervous system trauma and stroke. I. Physiological and pharmacological evidence for involvement of oxygen radicals and lipid peroxidation. Free Rad. Biol. Med. 6 (1989) 303-313
51. Hall N.A., Lake B.D., Dewji N.N., and Patrick A.D. Lysosomal storage of subunit C of mitochondrial ATP synthase in Batten's disease; (ceroid-lipofuscinosis). Biochem. J. 275 (1991) 269-272
52. Halliwell B. Oxidants and the central nervous system: some fundamental questions. Acta Neurol. Sand. 126 (1989) 23-33
53. Handelman G.J., and Dratz E.A. The role of antioxidants in the retina and retinal pigment epithelium and the nature of prooxdant-induced damage. Adv. Free Rad. Biol. Med. 2 (1986) 1-89
54. Harding A.E., Muller D.P.R., Thomas P.K., and Willison H.J. Spinocerebellar degeneration secondary to chronic intestinal malabsorption: A vitamin E deficiency syndrome. Ann. Neurol. 12 (1982) 419-424
55. Harries J.T., and Muller D.P.R. Absorption of vitamin E in children with biliary obstruction. Gut 12 (1971) 579-584
56. Hegele A., and Angel A. Arrest of neuropathy and myopathy in abetalipoproteinemia with high-dose vitamin E therapy. Can. Med. Assoc. J. 132 (1985) 41-44
57. Herbert P.N., Gotto A.M., and Fredrickson D.S. Familial lipoprotein deficiency. In: Stanbury J.B., Wyngaarden D.S., and Fredrickson D.S. (Eds). "The Metabolic Basis of Inherited Disease" (1978), McGraw Hill, New York 544-588
58. Hirsch E.C. Why are nigral catecholaminergic neurons more vulnerable than other cells in Parkinson's disease?. Ann. Neurol. 32 (1992) S88-S93
59. Howard L., Oveson L., Satya-Murti S., and Chu R. Reversible neurological symptoms caused by vitamin E deficiency in a patient with short bowel syndrome. Am. J. Clin. Nutr. 36 (1982) 1243-1249
60. Imaizumi S., Woolworth V., Fishman R.A., and Chan P.H. Liposome-entrapped superoxide dismutase reduces cerebral infarction in cerebral ischemia in rats. Stroke 21 (1990) 1312-1317
61. Ingold K.U., Burton G.W., Foster D.O., Hughes L., Lindsay D.A., and Webb A. Biokinetics of and discrimination between dietary RRR- and SRR-α-tocopherols in the male rat. Lipids 22 (1987) 163-172
62. Jeandel C., Nicolas M.B., Dubois F., Nabet-Belleville F., Penin F., and Cury G. Lipid peroxidation and free radical scavengers in Alzheimer's disease. Gerentology 35 (1989) 275-282
63. Jenner P., Sian J.D.D.T., Schapira A.H.V., and Marsden C.D. Oxidative stress as a cause of nigral cell death in Parkinson's disease and incidental Lewy body disease. Ann. Neurol. 32 (1992) S82-S87
64. Kane J.P., and Havel R.J. Disorders of the biogenesis and secretion of lipoproteins containing the B apolipoproteins. In: Scriver C.R., Beaudet A.L., Sly W.S., and Valle D. (Eds). "The Metabolic Basis of Inherited Disease" (1989), McGraw Hill, New York 1139-1164
65. Kellner M.J., and Bagnell R. Alteration of endogenous glutathione peroxidase, manganese superoxide dismutase and glutathione transferase activity in cells transfected with a copper-zinc superoxide dismutase expression vector. J. Biol. Chem. 265 (1990) 10872-10875
66. Kinouchi H., Epstein C.J., Mizui T., Carlson E., Chen S.F., and Chan P.H. Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing Cu Zn superoxide dismutase. Proc. Natl. Acad. Sci. U.S.A. 88 (1991) 11158-11162
67. Korpi E.R., and Wyatt R.J. Reduced haloperidol: Effects on striatal dopamine metabolism and conversion to haloperidol in the rat. Psychopharmacology 83 (1984) 34-37
68. Kretzer F.L., and Hittner H.M. Retinopathy of prematurity: Clinical implications of retinal development. Arch. Dis. Child. 63 (1988) 1151-1167
69. Lake B.D. Lysosomal and peroxisomal disorders. In: Adams J.H., and Duchen L.W. (Eds). "Greenfield's Neuropathology" (1992), Edward Arnold, London 709-810
70. Langston J.W., Ballard P., Tetrud J.W., and Irwin I. Chronic parkinsonism in humans due to a product of merperidine-analog synthesis. Science 219 (1983) 979-980
71. Law M.R., Wijewardene K., and Wald N.J. Is routine vitamin E administration justified in very low birth weight infants?. Dev. Med. Child. Neurol. 32 (1990) 442-450
72. Lemke M., Ames B.N.B., and Faden A.I. Decrease in tissue levels of ubiquinol-9 and -10, ascorbate and α-tocopherol following spinal cord impact trauma in rats. Neurosci. Lett. 108 (1990) 201-206
73. Lohr J.B., Jeste D.V.C.M.A., and Wyatt R.J. Alpha-tocopherol in tardive dyskinesia. Lancet 1 (1987) 913-914
74. Lohr J.B., Kuczenski R., Bracha H.S., Moir M., and Jeste D.V. Increased indices of free radical activity in the cerebrospinal fluid of patients with tardive dyskinesia. Biol. Psych. 28 (1990) 535-539
75. Macevilly C.J., and Muller D.P.R. Lipid peroxidation in neural tissues and fractions from vitamin E deficient rats. Free Rad. Biol. Med. 20 (1996) 639-648
76. Machlin L.J., Filipski R., Nelson J.S., Horn L.R., and Brin M. Effects of a prolonged vitamin E deficiency. J. Nutr. 107 (1977) 1200-1208
77. Mann D.M.A., and Yates P.O. Possible role of neuromelanin in the pathogenesis of Parkinson's disease. Mech. Ageing Dev. 21 (1983) 193-203
78. Martin J.E., Hindmarsh A., Merryweather I., and Muller D.P.R. Antioxidant deficit in the Mnd mouse. Brain Pathol. 4 (1994) 458
79. Martin J.E., Jowatt V., Merryweather I., and Muller D.P.R. The effect of antioxidant supplementation in the Mnd mouse. Nreuropathol. Appl. Neurobiol. 21 (1995) 448
80. Metcalfe T., Bowen D.M., and Muller D.P.R. Vitamin E concentrations in human brain of patients with Alzheimer's disease, fetuses with Down's syndrome, centenarians and controls. Neurochem. Res. 14 (1989) 1209-1212
81. Miller R.G., Davis C.J.F., Illingworth D.R., and Bradley W. The neuropathy of abetalipoproteinemia. Neuropathy 30 (1980) 1286-1289
82. Mink R.B., Dutka A.J., Kumaroo K.K., and Hallenbeck J.M. No conversion of xanthine dehydrogenase to oxidase in canine cerebral ischemia. Am. J. Physiol. 259 (1990) H1655-H1659
83. Mizui T., Kinouchi H., and Chan P.H. Depletion of brain glutathione by buthionine sulfoximine enhances cerebral ischemic injury in rats. Am. J. Physiol. 262 (1992) H313-H317
84. Mogi M., Harada M., Kuichi K., Kondo T., Narabayashi H., Rausch D., Riederer P., Jellinger K., and Nagatsu T. Homospecific activity (activity per enzyme protein) of tyrosine hydroxylase increases in Parkinson's brain. J. Neural Transm. 72 (1988) 77-81
85. Molenaar I., Vos J., and Hommes F.A. Effect of vitamin E deficiency on cellular membranes. Vits. Horms. 30 (1972) 45-82
86. Muller D.P.R. Free radical problems of the newborn. Proc. Nutr. Soc. 46 (1987) 69-75
87. Muller D.P.R. Vitamin E therapy in retinopathy of prematurity. Eye 6 (1992) 221-225
88. Muller D.P.R., and Goss-Sampson M.A. Neurochemical, neurophysiological and neuropathological studies in vitamin E deficiency. Crit. Rev. Neurobiol. 5 (1990) 239-263
89. Muller D.P.R., Harries J.T., and Lloyd J.K. The relative importance of the factors involved in the absorption of vitamin E in children. Gut 15 (1974) 966-971
90. Muller D.P.R., Lloyd J.K., and Bird A.C. Long term management of abetalipoproteinaemia: Possible role for vitamin E. Arch. Dis. Child. 52 (1977) 209-214
91. Muller D.P.R., Lloyd J.K., and Wolff O.H. Vitamin E and neurological function. Lancet 1 (1983) 225-228
92. Nelson J.S. Effects of free radical scavengers on the neuropathology of mammalian vitamin E deficiency. In: Hayaishi O., and Mino M. (Eds). "Clinical and Nutritional Aspects of Vitamin E" (1987), Elsevier, Amsterdam 157-159
93. Nelson J.S., Fitch C.D., Fischer V.W., Broun G.O., and Chou A.C. Progressive neuropathologic lesions in vitamin E deficient Rhesus monkeys. J. Neuropathol. Exp. Neurol. 40 (1981) 166-186
94. Nelson J.S., Fitch C.D., Fischer V.W., Rosenblum J., Keating J., Prensky A., Celisia G., Broun G., Chou A., Machlin L., and Woolsey R. Progressive neuropathologic lesions with vitamin E deficiency in mammals including man. J. Neuropathol. Exp. Neurol. 37 (1978) 666
95. Ng Y.K., Fielder A.R., Shaw D.E., and Levene M.I. Epidemiology of retinopathy of prematurity. Lancet 11 (1988) 1235-1238
96. Olanow C.W. Oxidation reactions in Parkinson's disease. Neurology 40 (1990) 32-37
97. Olanow C.W. A radical hypothesis for neurodegeneration. Trends Neurosci. 16 (1993) 439-944
98. Ouahchi K., Arita M., Kayden H., Hentati F., Hamida M.B., Sokol R., Arai H., Inoue K., Mandel J., and Koenig M. Ataxia with isolated vitamin E deficiency is caused by mutations in the a-tocopherol transfer protein. Nature Genet. 9 (1995) 141-145
99. Owens W.C., and Owens E.U. Retrolental fibroplasia in premature infants. II. Studies on the prophylaxis of the disease: the use of alpha-tocopheryl acetate. Am. J. Ophthalmol. 32 (1949) 1631-1637
100. Parkinson Study Group. Effect of deprenyl on the progression of disability in early Parkinson's disease. N. Engl. J. Med. 321 (1989) 1364-1371
101. Parkinson Study Group. Effects of tocopherol and deprenyl on the progression of disability in early Parkinson's disease. N. Engl. J. Med. 328 (1993) 176-183
102. Phelps D.L. Vitamin E and retrolental fibroplasia in 1982. Pediatrics 70 (1982) 420-425
103. Pietronigro D.D., Housepian M., Demopoulos H.B., and Flamm E.S. Loss of ascorbic acid from injured feline spinal cord. J. Neurochem. 41 (1983) 1072-1076
104. Riederer P., Sofic E., Rausch W., Schmidt B., Reynolds G.P., Jellinger K., and Yaudim M.B.H. Transition metals, ferririn, glutathione, and ascorbic acid in parkinsonian brains. J. Neurochem. 52 (1989) 515-520
105. Rosen D.R., Siddique T., Patterson D., Figlewicz D.A., Sapp P.H.A., Donaldsdon D., Goto J., O'Regan J.P., Deng H., Rohmani Z., Krizus A., Mckenna-Yasek D., Cayabyab A., Gaston S.M., Berger R., Tanzi R.E., Halperin J.J., Hertzfeldt B., Van Den Berg R., Hung W., Bird T., Deng G., Mulder D.W., Smyth C., Laing N.G., Soriano E., Pericak-Vance M.A., Haines J., Rouleau G.A., Gusella J.S., Horvitz H.R., and Brown Jr. R.H. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 362 (1993) 59-62
106. Rosenblum J.L., Keating J.P., Prensky A.L., and Nelson J.S. A progressive neurologic syndrome in children with chronic liver disease. N. Engl. J. Med. 304 (1981) 503-508
107. Rossetti Z.L., Sotgiu Sharp D.E.A., Hadjiconstantinou M., and Neff N.H. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and free radicals in vitro. Biochem. Pharmacol. 37 (1988) 4573-4574
108. Rothstein J.D., Bristol L.A., Hostler B., Brown R.H.J., and Kuncl R.W. Chronic inhibition of superoxide dismutase produces apoptotic death of spinal neurons. Proc. Natl. Acad. Sci. USA 91 (1994) 4155-4159
109. Sakamoto A., Ohniski S.T., Ohnishi T., and Ogawa R. Relationship between free radical production and lipid peroxidation during ischemia-reperfusion injury in the rat brain. Brain Res. 554 (1991) 186-192
110. Santavuori P., Heiskala H., Westermarck T., Sainio K., and Moren R. Experience over 17 years with antioxidant treatment in Spielmeyer-Sjogren disease. Am. J. Med. Gen. Suppl. 5 (1988) 265-274
111. Saunders R.D., Dugan L.L., Demeduik P., Means E.D., Horrocks L.A., and Anderson D.K. Effects of methylprednisolone and the combination of α-tocopherol and selenium on arachidonic acid metabolism and lipid peroxidation in traumatized spinal cord tissue. J. Neurochem. 49 (1987) 24-31
112. Schapira A.H.V., Mann V.M., Cooper J.M., Krige D., Jenner P.J., and Marsden C.D. Mitochondrial function in Parkinson's disease. Ann. Neural. 32 (1992) S116-S124
113. Schapira A.H.V., Mann V.M., Dexter D., Cooper J.M., Daniel S.E., Jenner P., Clark J.B., and Marsden C.D. Anatomic and disease specificity of NADH CoQ reductase (complex 1) deficiency in Parkinson's disease. J. Neurochem. 55 (1990) 2142-2145
114. Shah S.N., and Johnson R.C. Antioxidant vitamin (A and E) status of Down's syndrome subjects. Nutr. Res. 9 (1989) 709-715
115. Sharp D., Blinderman K., Combs K.A., Kienzle B., Ricci B., Wager-Smith K., Gil C.M., Turck C.W., Bouma M., Rader D.J., Aggerbeck L.P., Gregg R.E., Gordon D.A., and Wetterau J.R. Cloning and Gene defects in microsomal triglyceride transfer protein associated with abetalipoproteinaemia. Nature 365 (1993) 65-69
116. Sian J., Dexter D.T., Lees A.L., Daniel S., Jenner P., and Marsden C.D. Glutathione-related enzymes in brain in Parkinson's disease. Ann. Neurol. 36 (1994) 356-361
117. Sinet P.M., Lejeune J., and Jerome H. Trisomy 21 (Down's syndrome), glutathione peroxidase, hexose monophosphate shunt and I.Q. Life Sci. 24 (1979) 29-34
118. Sinet P.M., Michelson A.M., Bazin A., Lejeune J., and Jerome H. Increase in glutathione peroxidase activity in erythrocytes from trisomy 21 subjects. Biochem. Biophys. Res. Commun. 67 (1975) 910-915
119. Smith C.D., Carney J.M., Starke-Reed P.E., Oliver C.N., Stadtman E.R., Floyd R.A., and Markesberry W.R. Excess brain protein oxidation and enzyme dysfunction in normal aging and Alzheimer's disease. Proc. Natl. Acad. Sci. U.S.A. 88 (1991) 10540-10543
120. Sokol R.J., Butler-Simon N., Conner C., Huebi J.E., Sinatra F.R., Suchy F.J., Heyman M.B., Perrault J., Rothbaum R.J., Levy J., Iannaccone S.T., Shneider B.L., Koch T.K., and Narkewicz M.R. Multicenter trial of d-α-tocopheryl polyethylene glycol 1000 succinate for treatment of vitamin E deficiency in children with chronic cholestasis. Gastroenterology 104 (1993) 1727-1735
121. Sokol R.J., Guggenheim M.A., Iannaccone S.T., Barkhaus P.E., Miller C., Silverman A., Ballistreri W.F., and Heubi J.E. Improved neurologic function after long term correction of vitamin E deficiency in children with chronic cholestasis. N. Engl. J. Med. 313 (1985) 1580-1586
122. Sokol R.J., Heubi J.E., Butler-Simon N., Mcclung H.J., Lilly J., and Silverman A. Treatment of vitamin E deficiency during chronic childhood cholestasis with oral d-α- tocopheryl polyethylene glycol-1000 succinate. Gastroenterology 93 (1987) 975-985
123. Sokol R.J., Kayden H.J., Bettis D.B., Traber M.G., Neville H., Ringel S., Wilson W.B., and Stumpf D.A. Isolated vitamin E deficiency in the absence of fat malabsorption-familiar and sporadic cases: Characterisation and investigation of causes. J. Lab. Clin. Med. 111 (1988) 548-559
124. Southam E., Thomas P.K., King R.H.M., Goss-Sampson M.A., and Muller D.P.R. Experimental vitamin E deficiency in rats: Morphological and functional evidence of abnormal axonal transport secondary to free radical damage. Brain 114 (1991) 915-936
125. Sperling M.A., Hiles D.A., and Kennerdell J.S. Electroretinographic responses following vitamin A therapy in a-beta-lipoproteinaemia. Am. J. Opthalmol. 73 (1972) 342-351
126. Subbarao K.V., Richardson J.S., and Ang L.C. Autopsy samples of Alzheimer's cortex show increased lipid peroxidation in vitro. J. Neurochem. 55 (1990) 342-345
127. Sung J.H., Park S.H., Mastri A.R., and Warwick W.J. Axonal dystrophy in the gracile nucleus in congenital biliary atresia and cystic fibrosis (mucoviscidosis): Beneficial effect of vitamin E therapy. J. Neuropathol. Exp. Neurol. 39 (1980) 584-597
128. Terry T.L. Extreme prematurity and fibroblastic overgrowth of persistent vascular sheath behind each crystalline lens. I. Preliminary report. Am. J. Ophthalmol. 25 (1942) 203-204
129. Tetrud J.W., and Langston J.W. The effect of deprenyl (Selegiline) on the natural history of Parkinson's disease. Science 245 (1989) 519-522
130. Thomas P.K., Cooper J.M., King R.H.M., Workman J.M., Schapira A.H.V., Goss-Sampson M.A., and Muller D.P.R. Myopathy in vitamin E deficient rats: Muscle fibre necrosis associated with disturbances of mitochondrial function. J. Anat. 183 (1993) 451-461
131. Thomas P.K., Landon D.N., and King R.H.M. Diseases of the peripheral nerve. In: Hume Adams J., Corsellis J.A.N., and Duchen L.W. (Eds). "Greenfield's Neuropathology" (1984), Edward Arnold, London
132. Towfighi J. Effects of chronic vitamin E deficiency on the nervous system of the rat. Acta Neuropatbol. 54 (1981) 261-267
133. Traystman R.J., Kirsch J.R., and Koehler R.C. Oxygen radical mechanisms of brain injury following ischemia and reperfusion. J. Appl. Physiol. 71 (1991) 1185-1195
134. Vatassery G.T., Angerhofer C.K., and Peterson F.J. Vitamin E concentrations in the brains and some selected peripheral tissues of selenium-deficient and vitamin E-deficient mice. J. Neurochem. 42 (1984) 554-558
135. Vatassery G.T., and Younoszai R. Alpha-tocopherol levels in various regions of the central nervous system of the rat and guinea pig. Lipids 13 (1978) 828-831
136. Volicer L., and Crino P.B. Involvement of free radicals in dementia of the Alzheimer type: A hypothesis. Neurobiol. Aging 11 (1990) 567-571
137. Wetterau J.R., Aggerbeck L.P., Bouma M., Eisenberg C., Munck A., Hermier M., Schmitz J., Gay G., Rader D.J., and Gregg R.E. Absence of microsomal triglyceride transfer protein in individuals with abetalipoproteinaemia. Science 258 (1992) 999-1001
138. Wichman A., Buchthal F., Pezeshkpour G.H., and Gregg R.E. Peripheral neuropathy in abetalipoproteinemia. Neurology 35 (1985) 1279-1289
139. Wijner L.M.M., Menteba-Van Heusel M., Pearson P.L., and Khan P.M. Assignment of a gene for glutathione peroxidase (GPXl) to human chromosome 3. Cytogenet. Cell. Genet. 22 (1978) 232-235
140. Willison H.J., Muller D.P.R., Matthews S., Jones S., Kriss A., Stead R.J., Hodson M.E., and Harding A.E. A study of the relationship between neurological function and serum vitamin E concentrations in patients with cystic fibrosis. J. Neurol. Neurosurg. Psych. 48 (1985) 1097-1102
141. Wisniewski K.E., Wisniewski H.M., and Wen G.Y. Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome. Ann. Neurol. 17 (1985) 278-282
142. Wolff O.H., Lloyd J.K., and Tonks E.L. A-beta-lipoproteinaemia with special reference to the visual defect. Exp. Eye Res. 3 (1964) 439-442
143. Yamarnoto M., Shirna T., Uozumi T., Sogabe T., Yamada K., and Kawasaki K. A possible role of lipid peroxidation in cellular damages caused by cerebral ischemia and the protective effect of alpha-tocopherol administration. Stroke 14 (1983) 977-982
144. Yoshida S., Abe K., Busto R., Watson B.D., Kogure K., and Ginsberg M.D. Influence of transient ischemia on lipid-soluble antioxidants, free fatty acids and energy metabolites in rat brain. Brain Res. 245 (1982) 307-316
145. Yoshida S., Busto R., Santiso M., and Ginsberg M.D. Brain lipid peroxidation induced by postischemic reoxygenation in vitro: Effect of vitamin E. J. Cereb. Blood Flow Metab. 4 (1984) 466-469
146. Zaman Z., Roche S., Fielder P., Frost P.G., Nirieila D.C., and Cayley A.C.D. Plasma concentrations of vitamins A and E and carotenoids in Alzheimer's disease. Age Ageing 21 (1992) 91-94
147. Zubenko G.S., and Cohen B.M. Effects of psychotropic agents on the physical properties of platelet membranes in vitro. Psychopharmacology 86 (1985) 369-373