Characterization and in vitro cytocompatibility of piezoelectric electrospun scaffolds

Acta Biomaterialia

Volumn 6, Issue 9, 2010, Pages 3550-3556

  Weber, N ^a   Lee, Y S ^a   Shanmugasundaram, S ^a   Jaffe, M ^a   Arinzeh, T L ^a  

^a NEW JERSEY INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Electrospinning; Piezoelectric; Polymer; Scaffold; Tissue engineering

Indexed keywords

CELL ADHESION; CELL PROLIFERATION; DIFFERENTIAL SCANNING CALORIMETRY; ELECTROSPINNING; FLUORESCENCE MICROSCOPY; FLUORINE COMPOUNDS; FOURIER TRANSFORM INFRARED SPECTROSCOPY; GENE EXPRESSION; SCAFFOLDS (BIOLOGY); SCANNING ELECTRON MICROSCOPY; THERMOGRAVIMETRIC ANALYSIS; TISSUE; TISSUE CULTURE; X RAY DIFFRACTION;

CELL BEHAVIOURS; CHARGE INFLUENCE; CYTOCOMPATIBILITY; ELECTRICAL CHARGES; ELECTROSPUN SCAFFOLDS; FIBROUS SCAFFOLDS; IN-VITRO; PIEZOELECTRIC; POLY(VINYLIDENE FLUORIDE-TRIFLUOROETHYLENE); TISSUES ENGINEERINGS;

PIEZOELECTRICITY;

MOLECULAR SCAFFOLD; PIEZOELECTRIC ELECTROSPUN SCAFFOLD; POLY(VINYLIDENE FLUORIDE TRIFLUOROETHYLENE); POLYSTYRENE; UNCLASSIFIED DRUG; BIOMATERIAL; MESSENGER RNA; POLYVINYL DERIVATIVE; VINYLIDENE FLUORIDE-TRIFLUOROETHYLENE COPOLYMER;

ARTICLE; CELL COUNT; CELL PROLIFERATION; CRYSTALLIZATION; DIFFERENTIAL SCANNING CALORIMETRY; ELECTROSPINNING; EXTRACELLULAR MATRIX; FOCAL ADHESION; GENE EXPRESSION; HUMAN; HUMAN CELL; PIEZOELECTRICITY; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPE; SKIN FIBROBLAST; THERMOGRAVIMETRY; X RAY DIFFRACTION; CELL ADHESION; CELL SURVIVAL; CHEMISTRY; CONFOCAL MICROSCOPY; CYTOLOGY; DRUG EFFECTS; ELECTRICITY; FIBROBLAST; GENE EXPRESSION REGULATION; GENETICS; INFRARED SPECTROSCOPY; METABOLISM; POROSITY; PROCEDURES; SCANNING ELECTRON MICROSCOPY; TEMPERATURE; TISSUE ENGINEERING; TISSUE SCAFFOLD;

BIOCOMPATIBLE MATERIALS; CALORIMETRY, DIFFERENTIAL SCANNING; CELL ADHESION; CELL PROLIFERATION; CELL SURVIVAL; ELECTRICITY; FIBROBLASTS; GENE EXPRESSION REGULATION; HUMANS; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, SCANNING; POLYVINYLS; POROSITY; RNA, MESSENGER; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TEMPERATURE; TISSUE ENGINEERING; TISSUE SCAFFOLDS; X-RAY DIFFRACTION;

EID: 77956739173     PISSN: 17427061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actbio.2010.03.035     Document Type: Article

References (31)

1. Sill TJ, von Recum HA. Electrospinning: applications in drug delivery and tissue engineering. Biomaterials 2008;29(13):1989-2006.
2. He W, Ma Z, Teo WE, Dong YX, Robless PA, Lim TC, et al. Tubular nanofiber scaffolds for tissue engineered small-diameter vascular grafts. J Biomed Mater Res: Part A 2009;90(1):205-16.
3. Li WJ, Cooper JA, Mauck RL, Tuan RS. Fabrication and characterization of six electrospun poly (alpha-hydroxyester)-based fibrous scaffolds for tissue engineering applications. Acta Biomater 2006;2(4):377-85.
4. Kim Y, Haftel VK, Kumar S, Bellamkonda RV. The role of aligned polymer fiberbased constructs in the bridging of long peripheral nerve gaps. Biomaterials 2008;29(21):3117-27.
5. Zong X, Bien H, Chung C-Y, Yin L, Fang D, Hsiao BS, et al. Electrospun finetextured scaffolds for heart tissue constructs. Acta Biomater 2005;26(26):5330-8.
6. Patlolla A, Collins G, Livingston Arinzeh T. Solvent-dependent properties of electrospun fibrous composites for bone tissue regeneration. Acta Biomater 2010;6(1):90-101.
7. Leong MF, Rasheed MZ, Lim TC, Chian KS. In vitro cell infiltration and in vivo cell infiltration and vascularization in a fibrous, highly porous poly (D, L-lactide) - scaffold fabricated by cryogenic electrospinning technique. J Biomed Mater Res: Part A 2009;91(1):231-40.
8. Nam J, Huang Y, Agarwal S, Lannutti J. Improved cellular infiltration in electrospun fiber via engineered porosity. Tissue Eng 2007;13(9):2249-57.
9. Yang XL, Gu JW, Zhu HS. Preparation of bioelectret collagen and its influence on cell culture in vitro. J Mater Sci: Mater Med 2005;17(8):767-71.
10. Kotwal A, Schmidt CE. Electrical stimulation alters protein adsorption and nerve cell interactions with electrically conducting biomaterials. Biomaterials 2001;22(10):1055-64.
11. Valentini RF, Vargo TG, Gardella JA, Aebischer P. Electrically charged polymeric substrates enhance nerve fibre outgrowth in vitro. Biomaterials 1992;13(3):183-90.
12. Xu Y, Takai M, Ishihara K. Protein adsorption and cell adhesion on cationic, neutral, and anionic 2-methacryloyloxyethyl phosphorylcholine copolymer surfaces. Biomaterials 2009;30(28):4930-8.
13. Sun T, Mai S, Norton D, Haycock JW, Ryan AJ, MacNeil S. Self-organization of skin cells in three-dimensional electrospun polystyrene scaffolds. Tissue Eng 2005;11(7-8): 1023-33.
14. Eberle G, Schmidt H, Eisenmenger W. Piezoelectric polymer electrets. IEEE Trans Dielectrics Electrical Insulation 1996;3:624-46.
15. Greiner A, Wendorff JH. Review electrospinning: a fascinating method for the preparation of ultrathin fibers. Angew Chem Int Ed 2007;46(30):5670-703.
16. Kim KJ, Kim GB. Curie transition, ferroelectric crystal structure and ferroelectricity of a VDF/TrFE (75/25) copolymer: 2. The effect of poling on curie transition and ferroelectric crystal structure. Polymer 1997;38(19):4881-9.
17. Cebe P, Runt J. P (VDF-TrFE)-layered silicate nanocomposites. Part 1. X-ray scattering and thermal analysis studies. Polymer 2004;45:1923-32.
18. Collins G, Seunguk Y, Recber A, Jaffe M. Thermal analysis of complex relaxation processes in poly (desaminotyrosyl-tyrosine arylates). Polymer 2007;48:975-88.
19. Muller PY, Janovjak H, Miserez AR, Dobbie Z. Processing of gene expression data generated by quantitative real-time RT-PCR. Biotechniques 2002;32(6):1372-4.
20. Pham QP, Sharma U, Mikos AG. Electrospinning of polymeric nanofibers for tissue engineering applications: a review. Tissue Eng 2006;12(5):1197-211.
21. Yee WA, Kotaki M, Liu Y, Lu X. Morphology, polymorphism behavior and molecular orientation of electrospun poly (vinylidene fluoride) fibers. Polymer 2007;48:512-21.
22. Uyar T, Besenbacher F. Electrospinning of uniform polystyrene fibers: the effect of solvent conductivity. Polymer 2008;49(24):5336-43.
23. Koombhongse S, Liu WL, Reneker DH. Flat polymer ribbons and other shapes by electrospinning. J Polym Sci Part B: Polym Phys 2001;39(21):2598-606.
24. Casper CL, Stephen JS, Tassi NG, Chase DB, Rabolt JF. Controlling surface morphology of electrospun polystyrene fibers: effect of humidity and molecular weight in electrospinning process. Macromolecules 2004;37:573-8.
25. Furukawa T, Johnson GE. Dielectric relaxations in a copolymer of vinylidene fluoride and trifluoroethylene. J Appl Phys 1981;52(2):940-3. (Pubitemid 11502287)
26. Lovinger AJ, Davis DD, Cais RE, Kometani JM. Compositional variation of the structure and solid-state transformations of vinylidene fluoride/ tetrafluoroethylene copolymers. Macromolecules 1988;21(1):78-83.
27. Catalani LH, Collins G, Jaffe M. Evidence for molecular orientation and residual charge in the electrospinning of poly (butylene terephthalate) nanofibers. Macromolecules 2007;40(5):1693-7.
28. Steele JG, Johnson G, Underwood PA. Role of serum vitronectin and fibronectin in adhesion of fibroblasts following seeding onto tissue culture polystyrene. J Biomed Mat Res 1992;26(7):861-84.
29. Barker SL, La Rocca PJ. Method of production and control of a commercial tissue culture surface. J Tissue Cult Methods 1994;16:151-3.
30. Stevens MM, George JH. Exploring and engineering the cell surface interface. Science 2005;310(5751):1135-8.
31. Fine EG, Valentini RF, Bellamkonda R, Aebischer P. Improved nerve regeneration through piezoelectric vinylidenefluoride-trifluoroethylene copolymer guidance channels. Biomaterials 1991;12:775-80.