Chapter 19. Estrogen Receptor Modulators: Effects in Non-Traditional Target Tissues

Annual Reports in Medicinal Chemistry

Volumn 31, Issue C, 1996, Pages 181-190

  Grese, Timothy A ^a   Dodge, Jeffrey A ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 77956727943     PISSN: 00657743     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0065-7743(08)60458-3     Document Type: Article

References (122)

1. Henderson B.E., Ross R.K., and Bemstein L. Cancer Res. 48 (1988) 246
2. Smith E.P., Boyd J., Frank G.R., Takahashi H., Cohen R.M., Specker B., Williams T.C., Lugahn D.B., and Korach K.S. N. Engl. J. Med. 331 (1994) 1056
3. Ciocca D.R., and Vargas Roig L.M. Endocr. Rev. 16 (1995) 35
4. Lindsay R., and Riggs B.L. In: Melton L.J. (Ed). Osteoporosis: Etiology, Diagnosis, and Management (1988), Raven, New York 333
5. Ross R.K., Pike M.C., Mack T.M., and Henderson B.E. In: Drife J.O., and Studd J.W.W. (Eds). HRT and Osteoporosis (1990), Springer-Verlag, London 209
6. Gath D., and Iles S. In: Drife J.O., and Studd J.W.W. (Eds). HRT and Osteoporosis (1990), Springer-Verlag, London 35
7. Henderson V.W., Paganini-Hill A., Emanuel C.K., Dunn M.E., and Buckwalter J.G. Arch. Neurol. 51 (1994) 896
8. Holinka C.F. Ann. N.Y. Acad. Sci. 734 (1994) 271
9. Session D.R., Kelly A.C., and Jewelewicz R. Fertility Sterility 2 (1993) 277
10. Colditz G.A., Hankinson S.E., Hunter D.J., Willett W.C., Manson J.E., Stampfer M.J., Hennekens C., Rosner B., and Speizer F.E. N. Engl. J. Med. 332 (1995) 1589
11. Miquei J.-F., and Gilbert J. J. Steroid. Biochem. Molec. Biol. 31 (1988) 525
12. Magarian R.A., Oveacre L.B., Singh S., and Meyer K.L. Curr. Med. Chem. 1 (1994) 61
13. Chander S.K., Sahota S.S., Evans T.R.J., and Luqmani Y.A. Crit. Rev. Oncol. Hematol. 15 (1993) 243
14. Jordan V.C. J. Cell. Biochem. (1995) 51
15. Evans G.L., and Turner R.T. Bone 17 (1995) 181S
16. McDonnell D.P., Clemm D.L., Hermann T., Goldman M.E., and Pike J.W. Mol. Endocrinol. 9 (1995) 660
17. Honjo H., Tanaka H., Kashiwagi T., Urabe M., Okada H., Hayashi M., and Hayashi K. Hormone Metab. Res. 27 (1995) 204
18. Sherwin B.B. Ann. N.Y. Acad. Sci. 749 (1994) 213
19. Barrett-Connor E., and Kritz-Silverstein D. J. Am. Med. Assn. 265 (1991) 1861
20. Stampfer M.J., and Colditz G.A. Prev. Med. 20 (1991) 47
21. Punnonen R.H., Jokela H.A., Dastidar P.S., Nevala M., and Laippala P.J. Maturitas 21 (1995) 179
22. J. Am. Med. Assn. 273 (1995) 199 Writing Group for the PEPI Trial
23. LaRosa J.C. Fertility and Sterility 62 suppl. 2 (1994) 140S
24. Mendelsohn M.E., and Karas R.H. Curr. Opin. Cardiol. 9 (1994) 619
25. Turner R.T., Riggs B.L., and Spelsberg T.C. Endocrine Rev. 15 (1994) 275
26. Lindsay R., Aitken J.M., and Anderson J.B. Lancet 1 (1976) 1038
27. Oursler M.J., Landers J.P., Riggs B.L., and Spelsberg T.C. Ann. Med. 25 (1993) 361
28. Clark J.H., and Markaverich B.M. Pharmacol. Ther. 21 (1982) 621
29. Lemon L.H. Acta Endocrinol. Supp. 233 (1980) 17
30. Fotsis T., Zhang Y., Pepper M.S., Adlercreutz H., Montesano R., Nawroth P.P., and Schweigerer L. Nature 268 (1994) 237
31. Mueller G.P., Johns W.F., Cook D.L., and Edgren R.A. J. Am. Chem. Soc. 80 (1958) 1769
32. Chinn L.J., Dygos J.H., Mares S.E., Aspinall R.L., and Ranney R.E. J. Med. Chem. 17 (1974) 351
33. Dygos J.H., and Chinn L.J. J. Org. Chem. 40 (1975) 685
34. Washburn S.A., Adams M.R., Clarkson T.B., and Adelman S.J. Am. J. Obstet. Gynecol. 169 (1993) 251
35. Bryant H.U., Wilson P.K., Adrian M.D., Cole H.W., Short L.L., Dodge J.A., Grese T.A., Sluka J.P., and Glasebrook A.L. J. Soc. Gynecol. Invest. 3 Suppl. (1996) 152A
36. J.A. Dodge, D.E. Magee, P. Shetter, H. Cole, D. Adrian and H.U. Bryant, J. Steroid Biochem. Molec. Biol., in press.
37. Tsutimi N. Biol. Pharm. Bull. 18 (1995) 1012
38. Dodge J.A., Glasebrook A., Phillips D.L., Cole H.W., Magee D.E., Serlin B., and Bryant H.U. J. Bone Miner. Res. 9 suppl. 1 (1994) S134
39. Utian W.H. Br. Med. J. 1 (1973) 579
40. Huppert L.C. Fertility and Sterility 31 (1979) 1
41. Beall P.T., Misra L.K., Yound R.L., Spjut H.J., Evans H.J., and Leblanc A. Calcif. Tissue Int. 36 (1984) 123
42. Chakraborty P.K., Brown J.L., Ruff C.B., Nelson M., and Mitchell A.S. J. Steroid Biochem. Molec. Biol. 40 (1991) 725
43. Stewart P.J., and Stem P.H. Endocrinology 118 (1986) 125
44. Young R.L., Goldzieher J.W., Elkind-Hirsch K., Hickox P.G., and Chakraborty P.K. Int. J. Fertility 36 (1991) 167
45. Clark J.H., and Markaverich B.M. Pharmac. Ther. 15 (1982) 467
46. Clark J.H., and Guthrie S.C. Biol. Reprod. 25 (1981) 667
47. Young R.L., Goldzieher J.W., Chakraborty P.K., Panko W.B., and Bridges C.N. Int. J. Fertility 36 (1991) 291
48. Jordan V.C. Br. J. Pharmacol. 110 (1993) 507
49. Turner R.T., Wakley G.K., Hannon K.S., and Bell N.H. Endocrinology 122 (1988) 1146
50. Grey A.B., Stapleton J.P., Evans M.C., Tatnell M.A., Ames R.W., and Reid I.R. Am. J. Med. 99 (1995) 636
51. Love R.R., Barden H.S., Mazess R.B., Epstein S., and Chappell R.J. Arch. Intem. Med. 154 (1994) 2585
52. Ward R.L., Morgan G., Dalley D., and Kelly P.J. Bone Mineral 22 (1993) 87
53. Kristensen B., Ejlertsen B., Dalgaard P., Larsen L., Holmegaard S.N., Transbøl I., and Mouridsen H.T. J. Clin. Oncol. 12 (1994) 992
54. Kenny A.M., Prestwood K.M., Pilbeam C.C., and Raisz L.G. J. Clin. Endocr. Metab. 80 (1995) 3287
55. Sismondi P., Biglia N., Giai M., Sgro L., and Campagnoli C. Anticancer Res. 14 (1994) 2237
56. Grey A.B., Stapleton J.P., Evans M.C., and Reid I.R. J. Clin. Endocr. Metab. 80 (1995)
57. Shewmon D.A., Stock J.L., Rosen C.J., Heiniluoma K.M., Hogue M.M., Morrison A., Doyle E.M., Ukena T., Weale V., and Baker S. Arterioscler. Thromb. 14 (1994) 1586
58. Love R.R., Wiebe D.A., Feyzi J.M., Newcomb P.A., and Chappell R.J. J. Natl. Cancer Inst. 86 (1994) 1534
59. Rutqvist L.E., and Mattson A. J. Natl. Cancer Inst. 85 (1993) 1398
60. Fisher B., Constantino J.P., Redmond C.K., Fisher E.R., Wickerham D.L., and Cronin W.M. J. Natl. Cancer Inst. 86 (1994) 527
61. Lancet 339 (1992) 1 Early Breast Cancer Trialists' Collaborative Group
62. Gylling H., Äntylä E.M., and Miettinen T.A. Atherosclerosis 96 (1992) 245
63. Guetta V., and Cannon III R.O. Circulation 92 suppl. 1 (1995) 164
64. Wiseman H., Quinn P., and Halliwell B. FEBS 330 (1993) 53
65. Williams J.K., and Adams M.R. Circulation 92 suppl. 1 (1995) 627
66. Fuchs-Young R., Glasebrook A.L., Short L.L., Draper M.W., Rippy M.K., Cole H.W., Magee D.E., Termine J.D., and Bryant H.U. Ann. N.Y. Acad. Sci. 761 (1995) 355
67. Kedar R.P., Bourne T.H., Powles T.J., Collins W.P., Ashley S.E., Cosgrove D.O., and Campbell S. Lancet 343 (1994) 1318
68. Assikis V.J., and Jordan V.C. Endocr. Relat. Cancer 2 (1995) 235
69. Kuo D.Y.-S., and Runowicz C.D. Med. Oncol. 12 (1995) 87
70. Robinson D.C., Bloss J.D., and Schiano M.A. Gynecol. Oncol. 59 (1995) 186
71. Osborne M.R., Hewer A., Hardcastle I.R., Carmichael P.L., and Phillips D.H. Cancer Research 56 (1996) 66
72. Williams G.M., Latropoulos M.J., Djordjevic M.V., and Kaltenberg O. Carcinogenisis 14 (1993) 315
73. Rauschning W., and Pritchard K. Breast Cancer Res. Treat. 31 (1994) 83
74. Sterbygaard L.E., Hernstedt J., and Thomsen J.F. Breast Cancer Res. Treat. 25 (1993) 57
75. Coombes R.C., Haynes B.P., Dowsett M., Quigley M., English J., Judson I.R., Griggs L.J., Potter G.A., McCague R., and Jarman M. Cancer Res. 55 (1995) 1070
76. Koh J.-I., Kubota T., Asanuma F., Yamada Y., Kawamura E., Hosoda Y., Hashimoto M., Yamamoto O., Sakai S., Maeda K., and Shiina E. J. Surg. Oncol. 51 (1992) 254
77. Gylling H., Pyrhönen S., Mäntylä E., Mäqenpää H., Kangas L., and Miettinen T.A. J. Clin. Oncol. 13 (1995) 2900
78. di Salle E., Zaccheo T., and Omati G. J. Steroid Biochem. Molec. Biol. 36 (1990) 203
79. Tomás E., Kauppila A., Blanco G., Apaja-Sarkkinen M., and Laatikainen T. Gynecol. Oncol. 59 (1995) 261
80. Löser R., Seibel K., Roos W., and Eppenberger U. J. Cancer Clin. Oncol. 21 (1985) 985
81. Ke H.Z., Simmons H.A., Pirie C.M., Crawford D.T., and Thompson D.D. Endocrinology 136 (1995) 2435
82. Chen H.K., Ke H.Z., Li C.H., Ma Y.F., Qi H., Crawford D.T., Pirie C.M., Simmons H.A., Jee W.S.S., and Thompson D.D. Bone 17 suppl. (1995) 175S
83. Ke H.Z., Chen H.K., Qi H., Pirie C.M., Simmons H.A., Ma Y.F., Jee W.S.S., and Thompson D.D. Bone 17 (1995) 491
84. White I.N.H., de Mattheis F., Davis A., Smith L.L., Croften-Sleigh C., Venitt S., Hewer A., and Phillips D.H. Carcinogenesis 13 (1992) 2197
85. Hard G.C., Latropoulos M.J., Jordan K., Radi L., Kaltenberg O.P., Imondi A.R., and Williams G.M. Cancer Res. 53 (1993) 4534
86. Willson T.M., Henke B.R., Momtahen T.M., Charifson P.S., Batchelor K.W., Lubahn D.B., Moore L.B., Oliver B.B., Sauls H.R., Triantafillou J.A., Wolfe S.G., and Baer P.G. J. Med. Chem. 37 (1994) 1550
87. Bain S.D., Celino D.L., Bailey M.C., Strachan M.J., Piggott J.R., and Labroo V.M. Calcified Tiss. 55 (1994) 338
88. Trivedi R.N., Chauhan S.C., Dwivedi A., Kamboj V.P., and Singh M.M. Contraception 51 (1995) 367
89. Hall T.J., Nyugen H., Schaueblin M., and Foumier B. Biochem. Biophys. Res. Comm. 216 (1995) 662
90. Sato M., Glasebrook A.L., and Bryant H.U. J. Bone Miner. Metab. 12 suppl. 2 (1995) S9
91. Anzano M.A., Peer C.W., Smith J.M., Mullen L.T., Shrader M.W., Logsdon D.L., Driver C.L., Brown C.C., Roberts A.B., and Sporn M.B. J. Natl. Cancer inst. 88 (1996) 123
92. Jones C.D., Jevnikar M.G., Pike A.J., Peters M.K., Black L.J., Thompson A.R., Falcone J.F., and Clemens J.A. J. Med. Chem. 27 (1984) 1057
93. Black L.J., Sato M., Rowley E.R., Magee D.E., Bekele A., Williams D.C., Cullinan G.J., Bendele R., Kauffman R.F., Bensch W.R., Frolik C.A., Termine J.D., and Bryant H.U. J. Clin. Invest 93 (1994) 63
94. Kauffman R.F., and Bryant H.U. Drug News Perspec 8 (1995) 531
95. M.W. Draper, D.E. Flowers, W.J. Huster and J.A. Neild in "Proceedings of the Fourth International Symposium on Osteoporosis and Consensus Development Conference", 1993 C. Christiansen, B. Riis, Eds., Handelstrykkeriert Aalborg Aps, Aalborg, Denmark, 1993, p. 119.
96. Evans G., Bryant H.U., Magee D., Sato M., and Turner R.T. Endocrinology 134 (1994) 2283
97. Turner C.H., Sato M., and Bryant H.U. Endocrinology 135 (1994) 2001
98. Fiorelli G., Gori F., Frediani U., Morelli A.M., Falchetti A., Benvenuti S., Masi L., and Brandi M.L. Biochem. Biophys. Res. Comm. 211 (1995) 857
99. Perez M.C., Furth E.E., Matzumura P.D., and Lyttle C.R. Biol. Reprod. 54 (1996) 249
100. Fuchs-Young R., Magee D.E., Cole H.W., Short L., Glasebrook A.L., Rippy M.K., Termine J.D., and Bryant H.U. Endocrinology 136 suppl. (1995) 57
101. T.A. Grese, J.P. Sluka, H.U. Bryant, H.W. Cole, J.R. Kim, D.E. Magee, E.R. Rowley and M. Sato, Biorg. Med. Chem. Lett., 6, in press (1996).
102. Kojima M., Tsuttsumi N., Nagata H., Itoh F., Ujiie A., Kawashima K., Endo H., and Okazaki M. Biol. Pharm. Bull. 17 (1994) 504
103. Tsutsumi N., Kawashima K., Arai N., Nagata H., Kojima M., Ujiie A., and Endo H. Bone and Mineral 24 (1994) 201
104. Wakeling A.E., and Bowler J. J. Steroid Biochem. Molec. Biol. 31 (1988) 645
105. Dukes M., Chester R., Yarwood L., and Wakeling A.E. J. Endocrinology 141 (1994) 335
106. Dodge J.A., Stocksdale M.G., Black L.J., Rowley E.R., Bekele A., Cole H.W., Brown C.E., Magee D.E., Dehoney G.A., and Bryant H.U. J. Bone Miner. Res. 8 suppl. 1 (1993) S278
107. Wakeling A.E. Breast Cancer Res. Treat 25 (1993) 1
108. Baer P.G., Willson T.M., and Morris D.C. Calcifed Tissue Int. 55 (1994) 338
109. Jordan V.C. Cancer 70 (1992) 977
110. Weiss D.J., and Gurpide E. J. Steroid Biochem. Molec. Biol. 31 (1988) 671
111. Nemere I., Zhou L.-X., and Norman A.W. Receptor 3 (1993) 277
112. Colletta A.A., Benson J.R., and Baum M. Breast Cancer Res. Treat. 31 (1994) 5
113. Hendry L.B., Chu C.K., Rosser M.L., Copland J.A., Wood J.C., and Mahesh V.V. J. Steroid Biochem. Molec. Biol. 49 (1994) 269
114. Wolf D.M., and Fuqua S.A.W. Cancer Treat. Rev. 21 (1995) 247
115. Katzenellenbogen B.S., Montano M.M., Le Goff P., Schodin D.J., Kraus W.L., Bhardwaj B., and Fujimoto N. J. Steroid Biochem. Molec. Biol. 53 (1995) 387
116. Kumar V., Green S., Stack G., Berry M., Jin J.R., and Chambon P. Cell 54 (1988) 199
117. Berry M., Metzger D., and Chambon P. EMBO J. 9 (1990) 2811
118. Tzukerman M.T., Esty A., Santiso-Mere D., Danielian P., Parker M.G., Stein R.B., Pike J.W., and McDonnell D.P. Mol. Endocrinol. 8 (1994) 21
119. Umayahara Y., Kawamori R., Watada H., Imano E., Iwams N., Morishima T., Yamasaki Y., Kajimoto Y., and Kamada T. J. Biol. Chem. 269 (1994) 16433
120. Webb P., Lopez G.N., Uht R.M., and Kushner P.J. Mol. Endocrinol. 9 (1995) 443
121. Yang N.N., and Hardiker S. J. Bone Miner. Res. 9 suppl. 1 (1994) S144
122. McDonnell D.P., Dana S.L., Hoener P.A., Lieberman B.A., Imhof M.O., and Stein R.B. Ann. N.Y. Acad. Sci. 761 (1995) 121