α1-Adrenoceptor Subtypes in the Human Carondiovascular and Urogenital Systems

Advances in Pharmacology

Volumn 42, Issue C, 1997, Pages 394-398

  Michel, Martin C ^a   Taguchi, Katsunari ^a   Schäfers, Rafael S ^a   Williams, Timothy J ^b   Clarke, David E ^b   Ford, Anthony P D W ^b  

^a UNIVERSITY OF DUISBURG ESSEN   (Germany)

^b Neurobiology Unit Roche Bioscience Palo   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 77956724464     PISSN: 10543589     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S1054-3589(08)60772-3     Document Type: Article

References (6)

1. Schäfers R.F., Poller U., Ponicke K., Geissler M., Dad A.E., Michel M.C., and Brodde O.-E. Adrenergic and muscarinergic blockade and the cardiovascular effects of exogenously administered and endogenously released noradrenaline in humans. Naunyn Schmiedebergs Arch. Pharmacol 335 (1996) 239-249
2. 1- and β 2-adrenoceptor-mediated effects in humans. Am. J. Physiol. 254 (1988) H199-H206
3. Michel M.C., Grübbel B., Taguchi K., Verfürth F., Otto T., and Kröpfl D. Drugs for treatment of benign prostatic hyperplasia: Affinity comparison at cloned α 1-adrenoceptor subtypes and in human prostate. J. Auton. Pharmacol 16 (1996) 21-28
4. Ford A.P.D.W., Arredondo N.F., Blue D.R., Bouhaus D.W., Jasper J.R., Kava M.S., Lesnick J., Pfister J.R., Shiely I.A., Vimont R.L., Williams T.J., McNeal J.E., Stamey T.A., and Clarke D.E. RS-17053 (N-[2-cyclopropylmethoxy-phenoxy)-ethyl]-5-chloro-α,α-dimethyl-1H-indole-3-ethanamine hydrochloride), a selective α 1A,-adrenoceptor antagonist, displays low affinity for functional α 1A,-adrenoceptors in human prostate: Implications for adrenoceptor classification. Mol. Pharmacol 49 (1996) 209-215
5. Chess-Williams R., Chapple C.R., Verfürth F., Noble A.J., Couldwell C.J., and Michel M.C. SB 216469, an antagonist which discriminates between the α 1A,-adrenoceptor and the human prostatic α 1-adrenoceptor. Br. J. Pharmacol 119 (1996) 1093-1100
6. Williams T.J., Clarke D.E., and Ford A.P.D.W. Whole-cell radioligand binding assay reveals alL-adrenoceptor (AR) antagonist profile for the human cloned α 1A-AR in Chinese hamster ovary (CHO-K1) cells. Br. J. Pharmacol. 119 (1996) 359 Suppl.