Regulation of the Stoichiometry of Protein Components of the Stimulatory Adenylyl Cyclase Cascade

Advances in Pharmacology

Volumn 42, Issue C, 1997, Pages 462-465

  Milligan, G ^a   Mullaney, I ^a   Kim, G D ^a   MacEwan, D ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 77956724108     PISSN: 10543589     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S1054-3589(08)60788-7     Document Type: Article

References (5)

1. Adie E.J., and Milligan G. Regulation of basal adenylate cyclase activity in neurohlastoma x glioma hybrid, NG108-15, cells transfected to express the human β 2-adrenoceptor: Evidence for empty receptor stimulation of the adenylate cyclase cascade. Biochem. J 303 (1994) 803-808
2. Adie E.J., and Milligan G. Agonist regulation of cellular G, α-subunit levels in neuroblastoma x glioma hybrid NG108-15 cells transfected to express different levels of the human β 2-adrenoceptor. Biorhem. J 300 (1994) 709-715
3. MacEwan D.J., Kim G.D., and Milligan G. Analysis of the role of receptor number in defining the intrinsic activity and potency of partial agonists in neurohlastoma x glioma hybrid NG108-15 cells transfected to express different levels of the human β 2-adrenoceptor. Mol. Pharmacol 48 (1995) 316-325
4. Mullaney I., and Milligan G. Equivalent regulation of wild type and an epitopetagged variant of G sα by the IP prostanoid receptor following expression in neuroblastoma x glioma hybrid, NG108-15 cells. FEBS Lett 353 (1994) 231-234
5. MacEwan D.J., Kim G.D., and Milligan G. Agonist regulation of adenylate cyclase activity in neuroblastoma x glioma hybrid NG108-15 cells transfected to coexpress adenylate cyclase type II and the β 2-adrenoceptor. Evidence that adenylate cyclase is the limiting component for receptor-mediated stimulation of adenylyl cyclase activity. Biochem. J 318 (1996) 1033-1039