Mitochondrial Import of Cytochrome C

Advances in Molecular and Cell Biology

Volumn 17, Issue C, 1996, Pages 103-126

  Dumont, Mark E ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

EID: 77956718658     PISSN: 15692558     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S1569-2558(09)60011-4     Document Type: Article

References (76)

1. Baker K.P., and Schatz G. Mitochondrial genes essential for viability mediate protein import into yeast mitochondria. Nature 348 (1991) 605-609
2. Barker P.D., Ferrer J.C., Muthusamy M., Loehr T.M., Feng R., Konishi Y., Funk W., MacGillivray R.T.A., and Mauk A.G. Transmutation of a heme protein. Proc. Natl. Acad. Sci. USA 90 (1993) 6542-6546
3. Basile G., Di Bello C., and Taniuchi H. Formation of and iso-I-cytochrome c-like species containing a covalently bonded heme group from apoprotein by a yeast cell-free system in the presence of hemin. J. Biol. Chem. 255 (1980) 7181-7191
4. Beckman D.L., Trawick D.R., and Kranz R.G. Bacterial cytochromes c biogenesis: Involvement of a putative heme transporter and other novel components. Genes and Dev. 6 (1992) 268-283
5. Beckman D.L., and Kranz R.G. Cytochromes c biogenesis in a photosynthetic bacterium requires a periplasmic thioredoxin-like protein. Proc. Natl. Acad Sci. USA 90 (1993) 2179-2183
6. Bedwell D.M., Klionsky D.L., and Emr S. The yeast F1-ATPase β-subunit contains functionally redundant mitochondrial protein import information. Mol. Cell. Biol. 7 (1987) 4038-4047
7. Cohen J.S., Fisher W., and Schechter A.N. Spectroscopic studies on the conformation of cytochrome c and apocytochrome c. J. Biol. Chem. 249 (1974) 1113-1118
8. de Jongh H.H.J., Killian J.A., and de Kruijff B. A water-lipid interface induces a highly dynamic folded state in apocytochrome c and cytochrome c, which may represent a common folding intermediate. Biochemistry 31 (1992) 1636-1643
9. Cortese J.G., and Hackenbrock C.R. Motional dynamics of functional cytochrome c delivered by low pH fusion into the intermembrane space of intact mitochondria. Biochim. Biophys. Acta 1142 (1993) 194-202
10. Dihanich M., Suda K., and Schatz G. A yeast mutant lacking mitochondrial porin is respiratory-deficient but can recover respiration with simultaneous accumulation of an 86-kd extramitochondrial protein. EMBO J. 6 (1987) 723-728
11. Drygas M.E., Lambowitz A.M., and Nargang F.E. Cloning and analysis of the Neurospora crassa gene for cytochrome c heme lyase. J. Biol. Chem. 264 (1989) 17897-17906
12. Dumont M.E., and Richards F.M. Insertion of apocytochrome c into lipid vesicles. J. Biol. Chem. 259 (1984) 4147-4156
13. Dumont M.E., Ernst J.F., Hampsey D.M., and Sherman F. Identification and sequence of the gene encoding cytochrome c heme lyase in the yeast Saccharomyces cerevisiae. EMBO J. 6 (1987) 235-241
14. Dumont M.E., Ernst J.F., and Sherman F. Coupling of heme attachment to import of cytochrome c into yeast mitochondria: Studies with heme lyase-deficient mitochondria and altered apocytochromes c. J. Biol. Chem. 263 (1988) 15928-15937
15. Dumont M.E., Mathews A.J., Nall B.T., Baim S.B., Eustice D.C., and Sherman F. Differential stability of two apo-isocytochromes c in the yeast Saccharomyces cerevisiae. J. Biol. Chem. 265 (1990) 2733-2739
16. Dumont M.E., Cardillo T.S., Hayes M.K., and Sherman F. Role of cytochrome c heme lyase in mitochondrial import and accumulation of cytochrome c in Saccharomyces cerevisiae. Mol. Cell. Biol. 11 (1991) 5487-5496
17. Dumont M.E., Schlichter J., Cardillo T.S., Hayes M.K., Bethlendy G., and Sherman F. CYC2 encodes a factor involved in mitochondrial import of yeast cytochrome c. Mol. Cell. Biol. 13 (1993) 6442-6451
18. Dumont M.E., Corin A.F., and Campbell G.A. Noncovalent binding of heme induces a compact apocytochrome c structure. Biochemistry 33 (1994) 7368-7378
19. Enosawa S., and Ohashi A. Localization of enzyme for heme attachment to apocytochrome c in yeast mitochondria. Biochem. Biophys. Res. Commun. 141 (1986) 1145-1150
20. Fisher W.R., Taniuchi H., and Anfinson C.B. On the role of heme in the formation of the structure of cytochrome c. J. Biol. Chem. 248 (1973) 3188-3195
21. Fytlovich S., Gervais M., Agrimonti C., and Guiard B. Evidence for an interaction between the CYP1 (HAP1) activator and a cellular factor during heme-dependent transcritptional regulation in the yeast Saccharomyces cerevisiae. EMBO J. 12 (1993) 1209-1218
22. Glick B., and Schatz G. Import of proteins into mitochondria. Annu. Rev. Genet. 25 (1991) 21-44
23. Hakvoort T.B.M., Sprinkle J.R., and Margoliash E. Reversible import of apocytochrome c into mitochondria. Proc. Natl. Acad. Sci. USA 87 (1990) 4996-5000
24. Hampsey D.M., Das G., and Sherman F. Yeast iso-1-cytochrome c: Genetic analysis of structural requirements. FEBS Lett. 231 (1988) 275-283
25. Hartl F.-U., and Neupert W. Protein sorting to mitochondria: Evolutionary conservation of folding and assembly. Science 247 (1990) 930-938
26. Hennig B., and Neupert W. Assembly of cytochrome c: Apocytochrome c is bound to specific sites on mitochondria before its conversion to holocytochrome c. Eur. J. Biochem. 121 (1981) 203-212
27. Hennig B., Koehler H., and Neupert W. Receptor sites involved in post-translational transport of apocytochrome c into mitochondria: Specificity, affinity, and number of sites. Proc. Natl. Acad. Sci. USA 80 (1983) 4963-4967
28. Hennig B., Koehler H., and Neupert W. Transport of cytochrome c into mitochondria: Involvement of specific receptors and of cytochrome c heme lyase. Mitochondria. 30th ed (1983), Walter de Guyer & Co., Berlin 1983
29. Hickey D.R., Jayaraman K., Goodhue C.T., Shah J., Clements J.M., Tsunasawa S., and Sherman F. Synthesis and expression of genes encoding tuna, pigeon, and horse cytochromes c in the yeast Saccharomyces cerevisiae. Gene 105 (1991) 73-81
30. Holzschu D., Principio L., Conklin K.T., Hickey D.R., Short J., Rao R., McLendon G., and Sherman F. Replacement of the invariant lysine 77 by arginine in yeast iso-1-cytochrome c results in enhanced and normal activities in vitro and in vivo. J. Biol. Chem. 262 (1987) 7125-7131
31. Jordi W., Li-Xin Z., Pilon M., Demel R., and de Kruijff B. The importance of the amino terminus of the mitochondrial precursor protein cytochrome c for translocation across model membranes. J. Biol. Chem. 264 (1989) 2292-2301
32. Jordi W., Hergersberg C., and de Kruijff B. Bilayer-penetrating properties enable apocytochrome c to follow a special import pathway into mitochondria. Eur. J. Biochem. 204 (1992) 841-846
33. Kaput J., Brandriss M., and Prussak-Wieckowska T. In vitro import of cytochrome c peroxidase into the intermembrane space: Release of the processed form by intact mitochondria. J. Cell Biol. 109 (1989) 101-112
34. Kiebler M., Brecker K., Pfanner N., and Neupert W. Mitochondrial protein import: Specific recognition and membrane translocation of preproteins. J. Membr. Biol. 135 (1993) 191-207
35. Korb H., and Neupert W. Biogenesis of cytochrome c in Neurospora crassa. Eur. J. Biochem. 91 (1978) 609-620
36. Lamberg R., and Legge J.W. Hematin Compounds and Bile Pigments (1949), Interscience Publishers, New York 456-470
37. Leighton J., and Schatz G. An ABC transporter in the mitochondrial inner membrane is required for normal growth of yeast. EMBO J. 14 (1995) 188-195
38. Lill R., Stuart R.A., Drygas M.E., Nargang F.E., and Neupert W. Import of cytochrome c heme lyase into mitochondria: A novel import pathway into the intermembrane space. EMBO J. 11 (1992) 449-456
39. Magdolen V., Schricker R., Strobel G., Germaier H., and Bandlow W. In vivo import of yeast adenylate kinase into mitochondria affected by site-directed mutagenesis. FEBS Lett. 299 (1992) 262-272
40. Mannella C.A., Guo X.W., and Dias J. Binding of a synthetic peptide to a mitochondrial channel protein. J. Bioenergetics and Biomembranes 24 (1992) 55-61
41. Mannella C.A., Ribeiro A.J., and Frank J.A. Cytochrome c binds to lipid domains in arrays of mitochondrial outer membrane channels. Biophys. J. 51 (1987) 221-226
42. Matner R.R., and Sherman F. Differential accumulation of two apo-iso-cytochromes c in processing mutants of yeast. J. Biol. Chem. 257 (1982) 9811-9821
43. Matsuura S., Arpin M., Hannum C., Margoliash E., Sabatini D.D., and Morimoto T. In vitro synthesis and posttranslational uptake of cytochrome c into isolated mitochondria, role of a specific addressing signal in the apocytochrome. Proc. Natl. Acad. Sci. USA 78 (1981) 4368-4372
44. Mayer A., Neupert W., and Lill R. Translocation of apocytochrome c across the outer mitochondrial membrane of mitochondria. J. Biol. Chem. 270 (1995) 12390-12397
45. Muga A., Mantsch H.H., and Surewicz W.K. Membrane binding induces destabilization of cytochrome c structure. Biochemistry 30 (1991) 7219-7224
46. Murakami H., Pain D., and Blobel G. 70 kD heat shock related protein is one of at least two distinct cytosolic factors stimulating protein import into mitochondria. J. Cell Biol. 107 (1988) 2051-2057
47. Nargang F.E., Drygas M.E., Kwong P.L., Nicholson D.W., and Neupert W. A mutant of Neurospora crassa deficient in cytochrome c heme lyase activity can not import cytochrome c into mitochondria. J. Biol. Chem. 263 (1988) 9388-9394
48. Nicholson D.W., Hergersberg C., and Neupert W. Role of cytochrome c heme lyase in the import of cytochrome c into mitochondria. J. Biol. Chem. 263 (1988) 19034-19042
49. Nicholson D.W., and Neupert W. Import of cytochrome c into mitochondria: Reduction of heme, mediated by NADH and flavin nucleotides is obligatory for its covalent linkage to apocytochrome c. Proc. Natl. Acad. Sci. USA 86 (1989) 4340-4344
50. Nye S.H., and Scarpulla R.C. In vivo expression and mitochondrial targeting of yeast apoiso-***1-cytochrome c fusion proteins. Mol. Cell. Biol. 10 (1990) 5753-5762
51. Nye S.H., and Scarpulla R.C. Mitochondrial targeting of yeast apoiso-1-cytochrome c is mediated through functionally independent structural domains. Mol. Cell. Biol. 10 (1990) 5763-5771
52. Page M.D., and Ferguson S.J. Apo forms of cytochrome c550 and cytochrome cdl are translocated to the periplasm of paracoccus denitificans in the absence of haem incorporation caused by either mutation or inhibition of heme synthesis. Mol. Microbiol 4 (1990) 1181-1192
53. Parr G.R., and Taniuchi H. An investigation of ordered complex formation with chemically modified fragments of cytochrome c. J. Biol. Chem. 255 (1980) 2616-2623
54. Pfanner N., Rasow J., van der Klei I., and Neupert W. A dynamic model of the mitochondrial protein import machinery. Cell 68 (1992) 999-1002
55. Pon L., Moll T., Vestweber D., Marshallsay B., and Schatz G. Protein import into mitochondria: ATP-dependent protein translocation activity in a submitochondrial fraction enriched in membrane contact sites and specific proteins. J. Cell Biol. 109 (1989) 2603-2616
56. Ramseier T.M., Winteler H.V., and Hennecke H. Discovery and sequence analysis of bacterial genes involved in the biogenesis of c-type cytochromes. J. Biol. Chem. 266 (1991) 7793-7803
57. Rietveld A., and De Kruijff B. Is the mitochondrial precursor protein apocytochrome c able to pass a lipid barrier? J. Biol. Chem. 259 (1984) 6704-6707
58. Ritz D., Bott M., and Hennecke H. Formation of several bacterial c-type cytochromes requires a novel membrane-anchored protein that faces the periplasm. Mol. Microbiol. 9 (1993) 729-740
59. Rothstein R.J., and Sherman F. Genes affecting the expression of cytochrome c in yeast: Genetic mapping and genetic interactions. Genetics 94 (1980) 871-889
60. Sadis S., and Hightower L.E. Unfolded proteins stimulate molecular chaperone Hsc70 ATPase by accelerating ADP/ATP exchange. Biochemistry 31 (1992) 9406-9412
61. Söllner T., Griffiths G., Pfaller R., Pfanner N., and Neupert W. MOM19, an import receptor for mitochondrial precursor proteins. Cell 59 (1989) 1061-1070
62. Sanbongi Y., Yang J.-H., Igarashi Y., and Kodoma T. Cloning and nucleotide sequence of the cytochrome c-551 gene from Hydrogenobacter thermopilus. Eur. J. Biochem. 198 (1991) 7-12
63. Sorrell T.N., and Martin P.K. A novel, functional variant of cytochrome c: Replacement of the histidine ligand with arginine via site-directed mutagenesis. J. Am. Chem. Soc. 111 (1989) 766-767
64. Sprinkle J.R., Hakvoort T.B.M., Koshy T.I., Miller D.D., and Margoliash E. Amino acid sequence requirements for the association of apocytochrome c with mitochondria. Proc. Natl. Acad. Sci. USA 87 (1990) 5729-5733
65. Stellwagen E., Rysavy R., and Babul G. The conformation of horse heart apocytochrome c. J. Biol. Chem. 247 (1972) 8074-8077
66. Stuart R.A., and Neupert W. Apocytochrome c an exceptional mitochondrial precursor protein using an exceptional import pathway. Biochemie 72 (1990) 115-121
67. Stuart R.A., Neupert W., and Tropschug M. Deficiency in mRNA splicing in a cytochrome c mutant of Neurospora crassa: Importance of carboxy terminus for import of apocytochrome c into mitochondria. EMBO J. 6 (1987) 2131-2137
68. ***1 sorting pathway. J. Biol. Chem. 265 (1990) 20210-20219
69. Stuart R.A., Nicholson D.W., and Neupert W. Early steps in mitochondrial protein import: Receptor functions can be substituted by the membrane insertion activity of apocytochrome c. Cell 60 (1990) 31-43
70. Takano T., and Dickerson R.E. Conformational change of cytochrome c. 1. Ferrocytochrome c structure refined at 1.5 A resolution. J. Mol. Biol. 153 (1981) 79-94
71. Tanaka Y., Kubota I., Amachi T., Yoshizumi H., and Matsubara H. Site-directed mutated human cytochrome c which retains heme c via only one thioether bond. J. Biochem. 108 (1990) 7-8
72. Veloso D., Juillerat M., and Taniuchi H. Synthesis of a heme fragment of horse cytochrome c which forms a productive complex with native apofragment. J. Biol. Chem. 259 (1984) 6067-6073
73. Wang X., Dumont M.E., and Sherman F. Sequence requirements for mitochondrial import of yeast cytochrome c. J. Biol. Chem. 271 (1996) 6594-6604
74. Wotczak L., and Zaluska H. On the impermeability of the outer mitochondrial membrane to cytochrome c. I. Studies on whole mitochondria. Biochim. Biophys. Acta 193 (1969) 64-72
75. Zimmerman R., Henning B., and Neupert W. Different transport pathways of individual precursor proteins in mitochondria. Eur. J. Biochem. 116 (1981) 455-460
76. ***1-heme lyase. Eur. J. Biochem. 207 (1992) 1093-1100