Asthma and gender impact accumulation of T cell subtypes

Respiratory Research

Volumn 11, Issue , 2010, Pages

  Loza, Matthew J ^a   Foster, Susan ^a   Bleecker, Eugene R ^a   Peters, Stephen P ^a   Penn, Raymond B ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 13; INTERLEUKIN 2; CD3 ANTIGEN; IL2 PROTEIN, HUMAN; RECOMBINANT PROTEIN;

ALLERGIC ASTHMA; ARTICLE; ASTHMA; CD3+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EX VIVO STUDY; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOREGULATION; MALE; PERIPHERAL LYMPHOCYTE; SEX DIFFERENCE; T LYMPHOCYTE; TH1 CELL; TH2 CELL; ADULT; CASE CONTROL STUDY; CELL CULTURE; COMPARATIVE STUDY; IMMUNOLOGY; IMMUNOPHENOTYPING; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COUNT; METABOLISM; T LYMPHOCYTE SUBPOPULATION;

ADULT; ANTIGENS, CD28; ANTIGENS, CD3; ASTHMA; CASE-CONTROL STUDIES; CELLS, CULTURED; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNOPHENOTYPING; INTERFERON-GAMMA; INTERLEUKIN-13; INTERLEUKIN-2; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COUNT; MALE; RECOMBINANT PROTEINS; SEX FACTORS; T-LYMPHOCYTE SUBSETS; TH1 CELLS; TH2 CELLS;

EID: 77956695436     PISSN: 14659921     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/1465-9921-11-103     Document Type: Article

References (22)

1. Busse WW, Lemanske RF. Asthma. N Engl J Med 2001, 344:350-362. 10.1056/NEJM200102013440507, 11172168.
2. Colavita AM, Reinach AJ, Peters SP. Contributing factors to the pathobiology of asthma. The Th1/Th2 paradigm. Clin Chest Med 2000, 21:263-77. viii, 10.1016/S0272-5231(05)70265-3, 10907587.
3. Holgate ST. Pathogenesis of asthma. Clin Exp Allergy 2008, 38:872-897. 10.1111/j.1365-2222.2008.02971.x, 18498538.
4. Holtzman MJ, Sampath D, Castro M, Look DC, Jayaraman S. The one-two of T helper cells: does interferon-gamma knock out the Th2 hypothesis for asthma?. Am J Respir Cell Mol Biol 1996, 14:316-318.
5. Krug N, Madden J, Redington AE, Lackie P, Djukanovic R, Schauer U, Holgate ST, Frew AJ, Howarth PH. T-cell cytokine profile evaluated at the single cell level in BAL and blood in allergic asthma. Am J Respir Cell Mol Biol 1996, 14:319-326.
6. Randolph DA, Stephens R, Carruthers CJ, Chaplin DD. Cooperation between Th1 and Th2 cells in a murine model of eosinophilic airway inflammation. J Clin Invest 1999, 104:1021-1029. 10.1172/JCI7631, 408580, 10525040.
7. Shaver JR, Zangrilli JG, Cho SK, Cirelli RA, Pollice M, Hastie AT, Fish JE, Peters SP. Kinetics of the development and recovery of the lung from IgE-mediated inflammation: dissociation of pulmonary eosinophilia, lung injury, and eosinophil-active cytokines. Am J Respir Crit Care Med 1997, 155:442-8.
8. Strachan DP. Hay fever, hygiene, and household size. Bmj 1989, 299:1259-1260. 10.1136/bmj.299.6710.1259, 1838109, 2513902.
9. Druilhe A, Wallaert B, Tsicopoulos A, Lapae Silva JR, Tillie-Leblond I, Tonnel AB, Pretolani M. Apoptosis, proliferation, and expression of Bcl-2, Fas, and Fas ligand in bronchial biopsies from asthmatics. Am J Respir Cell Mol Biol 1998, 19:747-757.
10. Valerius T, Repp R, Kalden JR, Platzer E. Effects of IFN on human eosinophils in comparison with other cytokines. A novel class of eosinophil activators with delayed onset of action. J Immunol 1990, 145:2950-2958.
11. Stock P, DeKruyff RH, Umetsu DT. Inhibition of the allergic response by regulatory T cells. Curr Opin Allergy Clin Immunol 2006, 6:12-16. 10.1097/01.all.0000200502.69672.44, 16505606.
12. Loza MJ, Perussia B. Final steps of natural killer cell maturation: a model for type 1-type 2 differentiation?. Nat Immunol 2001, 2:917-924. 10.1038/ni1001-917, 11577347.
13. Loza MJ, Metelitsa LS, Perussia B. NKT and T cells: coordinate regulation of NK-like phenotype and cytokine production. Eur J Immunol 2002, 32:3453-3462. 10.1002/1521-4141(200212)32:12<3453::AID-IMMU3453>3.0.CO;2-D, 12442327.
14. Loza MJ, Perussia B. Peripheral immature CD2-/low T cell development from type 2 to type 1 cytokine production. J Immunol 2002, 169:3061-3068.
15. Loza MJ, Perussia B. Accumulation of type 2 cytokine+ T cells: differentiation-independent proliferation of pre-existing type 2 T cells. Eur J Immunol 2003, 33:939-949. 10.1002/eji.200323643, 12672060.
16. Loza MJ, Foster S, Peters SP, Penn RB. Interactive effects of steroids and beta-agonists on accumulation of type 2 T cells. J Allergy Clin Immunol 2008, 121:750-755. 10.1016/j.jaci.2007.10.036, 18155275.
17. Loza MJ, Faust JS, Perussia B. Multiple color immunofluorescence for cytokine detection at the single cell level. Methods Mol Biol 2000, 121:193-209.
18. Balzano G, Fuschillo S, Melillo G, Bonini S. Asthma and sex hormones. Allergy 2001, 56:13-20. 10.1034/j.1398-9995.2001.00128.x, 11167347.
19. Loza MJ, Peters SP, Penn RB. Atopy, asthma, and experimental approaches based on the linear model of T cell maturation. Clin Exp Allergy 2005, 35:8-17. 10.1111/j.1365-2222.2004.02148.x, 15649260.
20. Gough PJ, Gordon S. The role of scavenger receptors in the innate immune system. Microbes Infect 2000, 2:305-311. 10.1016/S1286-4579(00)00297-5, 10758407.
21. Janeway CA. The immune system evolved to discriminate infectious nonself from noninfectious self. Immunol Today 1992, 13:11-16. 10.1016/0167-5699(92)90198-G, 1739426.
22. Vrieze A, Postma DS, Kerstjens HA. Perimenstrual asthma: a syndrome without known cause or cure. J Allergy Clin Immunol 2003, 112:271-282. 10.1067/mai.2003.1676, 12897732.